Nothing Special   »   [go: up one dir, main page]

DK3117012T3 - Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager - Google Patents

Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager Download PDF

Info

Publication number
DK3117012T3
DK3117012T3 DK15761889.3T DK15761889T DK3117012T3 DK 3117012 T3 DK3117012 T3 DK 3117012T3 DK 15761889 T DK15761889 T DK 15761889T DK 3117012 T3 DK3117012 T3 DK 3117012T3
Authority
DK
Denmark
Prior art keywords
methods
transplant recipient
immunosuppressive therapies
monitoring
monitoring immunosuppressive
Prior art date
Application number
DK15761889.3T
Other languages
English (en)
Inventor
Robert Woodward
Marica Grskovic
Jim Yee
Mitch Nelles
David Hiller
Original Assignee
Caredx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54072508&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3117012(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Caredx Inc filed Critical Caredx Inc
Application granted granted Critical
Publication of DK3117012T3 publication Critical patent/DK3117012T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK15761889.3T 2014-03-14 2015-03-13 Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager DK3117012T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461953582P 2014-03-14 2014-03-14
PCT/US2015/020603 WO2015138997A1 (en) 2014-03-14 2015-03-13 Methods of monitoring immunosuppressive therapies in a transplant recipient

Publications (1)

Publication Number Publication Date
DK3117012T3 true DK3117012T3 (da) 2019-05-13

Family

ID=54072508

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15761889.3T DK3117012T3 (da) 2014-03-14 2015-03-13 Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager

Country Status (15)

Country Link
US (9) US11767559B2 (da)
EP (1) EP3117012B1 (da)
CN (2) CN113528645A (da)
AU (3) AU2015229083B2 (da)
BR (1) BR112016021038B1 (da)
CA (1) CA2970916A1 (da)
DK (1) DK3117012T3 (da)
ES (1) ES2726650T3 (da)
HR (1) HRP20190759T1 (da)
HU (1) HUE043288T2 (da)
PL (1) PL3117012T3 (da)
PT (1) PT3117012T (da)
SI (1) SI3117012T1 (da)
TR (1) TR201907106T4 (da)
WO (1) WO2015138997A1 (da)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11111543B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US10113196B2 (en) 2010-05-18 2018-10-30 Natera, Inc. Prenatal paternity testing using maternal blood, free floating fetal DNA and SNP genotyping
CN102597266A (zh) 2009-09-30 2012-07-18 纳特拉公司 无创性产前倍性调用的方法
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US20190284623A1 (en) * 2010-05-18 2019-09-19 Natera, Inc. Methods for non-invasive prenatal ploidy calling
EP2854057B1 (en) 2010-05-18 2018-03-07 Natera, Inc. Methods for non-invasive pre-natal ploidy calling
US11332785B2 (en) * 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11339429B2 (en) * 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
JP6153874B2 (ja) 2011-02-09 2017-06-28 ナテラ, インコーポレイテッド 非侵襲的出生前倍数性呼び出しのための方法
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
PL3004388T5 (pl) * 2013-05-29 2023-10-09 Chronix Biomedical Wykrywanie i oznaczanie ilościowe pozakomórkowego dna dawcy w układzie krążenia biorców przeszczepów organów
US10577655B2 (en) 2013-09-27 2020-03-03 Natera, Inc. Cell free DNA diagnostic testing standards
DK3117012T3 (da) * 2014-03-14 2019-05-13 Caredx Inc Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager
CN113774132A (zh) 2014-04-21 2021-12-10 纳特拉公司 检测染色体片段中的突变和倍性
US10435750B2 (en) 2014-07-03 2019-10-08 Multiplicom N.V. Methods for non-invasive detection of transplant health or rejection
EP3294906B1 (en) 2015-05-11 2024-07-10 Natera, Inc. Methods for determining ploidy
CN106544407B (zh) * 2015-09-18 2019-11-08 广州华大基因医学检验所有限公司 确定受体cfDNA样本中供体来源cfDNA比例的方法
CN105483123B (zh) * 2015-11-23 2019-02-22 元码基因科技(北京)股份有限公司 遗传标记组合、个体基因身份证及其用途
US11485996B2 (en) 2016-10-04 2022-11-01 Natera, Inc. Methods for characterizing copy number variation using proximity-litigation sequencing
US20190367972A1 (en) * 2016-11-02 2019-12-05 The Medical College Of Wisconsin, Inc. Methods for assessing risk using total and specific cell-free dna
CN106520982B (zh) * 2016-12-05 2019-11-08 中国人民解放军军事医学科学院放射与辐射医学研究所 一种用于身份鉴定的复合分型系统
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
CN107058562B (zh) * 2017-05-17 2018-04-10 成都仕康美生物科技有限公司 Snp位点的应用及其检测试剂盒
CA3067637A1 (en) 2017-06-20 2018-12-27 The Medical College Of Wisconsin, Inc. Assessing transplant complication risk with total cell-free dna
US20210139983A1 (en) * 2017-06-20 2021-05-13 The Medical College Of Wisconsin, Inc. Transplant patient monitoring with cell-free dna
JP2021506342A (ja) 2017-12-14 2021-02-22 ティーエーアイ ダイアグノスティックス インコーポレイテッドTai Diagnostics,Inc. 移植のための移植片適合性の評価
AU2018383191B2 (en) * 2017-12-15 2023-02-16 Acrannolife Genomics Pvt. Ltd. A non-invasive method for monitoring transplanted organ status in organ-transplant recipients
CN107937571B (zh) * 2018-01-16 2021-12-07 良培基因生物科技(武汉)有限公司 一种基于信息snp集及其引物的核酸质谱亲权鉴定方法
EP3517629A1 (en) 2018-01-30 2019-07-31 Myway Genetics S.r.L. Use of cfdna fragments as biomarkers in patients after organ transplantation
EP3781714A1 (en) 2018-04-14 2021-02-24 Natera, Inc. Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna
CN112752852A (zh) * 2018-07-03 2021-05-04 纳特拉公司 用于检测供体来源的细胞游离dna的方法
US11525159B2 (en) * 2018-07-03 2022-12-13 Natera, Inc. Methods for detection of donor-derived cell-free DNA
CA3107467A1 (en) * 2018-09-07 2020-03-12 Sequenom, Inc. Methods, and systems to detect transplant rejection
WO2020076957A1 (en) * 2018-10-09 2020-04-16 Tai Diagnostics, Inc. Cell lysis assay for cell-free dna analysis
US20220073989A1 (en) * 2018-12-20 2022-03-10 The Regents Of The University Of California Optimizing Detection of Transplant Injury by Donor-Derived Cell-Free DNA
CA3128894A1 (en) * 2019-02-19 2020-08-27 Sequenom, Inc. Compositions, methods, and systems to detect hematopoietic stem cell transplantation status
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples
JP2023515665A (ja) * 2020-03-06 2023-04-13 デノボ バイオファーマ エルエルシー 神経伝達物質トランスポーターの阻害剤の有効性を評価するための組成物及び方法
US20210395835A1 (en) * 2020-06-19 2021-12-23 Caredx, Inc. Methods for monitoring allogeneic cells
CN113061666A (zh) * 2020-12-30 2021-07-02 中南大学湘雅二医院 肝移植后巨细胞病毒的检测方法、应用及系统
WO2023004203A1 (en) * 2021-07-23 2023-01-26 Georgetown University Use of genetic and epigenetic markers to detect cell death
US20230348985A1 (en) * 2022-03-21 2023-11-02 CarexDx, Inc. Methods for non-invasively monitoring organ health in cross-species transplantation

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39920E1 (en) * 1997-05-30 2007-11-13 Xenomics, Inc. Methods for detection of nucleic acid sequences in urine
US6132997A (en) 1999-05-28 2000-10-17 Agilent Technologies Method for linear mRNA amplification
ES2532153T3 (es) * 2008-07-18 2015-03-24 Trovagene, Inc. Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR
CN102712954A (zh) 2009-11-06 2012-10-03 小利兰·斯坦福大学托管委员会 器官移植患者移植排斥的非侵入性诊断
US20120034603A1 (en) 2010-08-06 2012-02-09 Tandem Diagnostics, Inc. Ligation-based detection of genetic variants
US10131947B2 (en) * 2011-01-25 2018-11-20 Ariosa Diagnostics, Inc. Noninvasive detection of fetal aneuploidy in egg donor pregnancies
CN102618626B (zh) * 2011-01-30 2014-05-14 杭州优思达生物技术有限公司 一种快速单核苷酸多态性的检测方法及试剂盒
US20130024127A1 (en) 2011-07-19 2013-01-24 John Stuelpnagel Determination of source contributions using binomial probability calculations
CA3069089A1 (en) * 2011-09-22 2013-03-28 Lineage Biosciences, Inc. Compositions and methods for analyzing heterogeneous samples
AU2012321053B2 (en) 2011-10-07 2018-04-19 Murdoch Childrens Research Institute Diagnostic assay for tissue transplantation status
CN204440396U (zh) * 2012-04-12 2015-07-01 维里纳塔健康公司 用于确定胎儿分数的试剂盒
EP2839036A4 (en) 2012-04-19 2016-03-16 Wisconsin Med College Inc HIGHLY SENSITIVE SURVEILLANCE USING ACELLULAR DNA DETECTION
PL3004388T5 (pl) 2013-05-29 2023-10-09 Chronix Biomedical Wykrywanie i oznaczanie ilościowe pozakomórkowego dna dawcy w układzie krążenia biorców przeszczepów organów
DK3117012T3 (da) * 2014-03-14 2019-05-13 Caredx Inc Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager
WO2018187226A1 (en) 2017-04-04 2018-10-11 The Board Of Trustees Of The Leland Stanford Junior University Quantification of transplant-derived circulating cell-free dna in the absence of a donor genotype
SG11201911538YA (en) 2017-06-20 2020-01-30 Illumina Inc Methods and systems for decomposition and quantification of dna mixtures from multiple contributors of known or unknown genotypes
CA3067418C (en) 2017-06-20 2022-08-16 Illumina, Inc. Methods for accurate computational decomposition of dna mixtures from contributors of unknown genotypes
CA3128894A1 (en) 2019-02-19 2020-08-27 Sequenom, Inc. Compositions, methods, and systems to detect hematopoietic stem cell transplantation status
US20210395835A1 (en) 2020-06-19 2021-12-23 Caredx, Inc. Methods for monitoring allogeneic cells

Also Published As

Publication number Publication date
US20230407393A1 (en) 2023-12-21
HUE043288T2 (hu) 2019-08-28
US20160145682A1 (en) 2016-05-26
US11767559B2 (en) 2023-09-26
US20230407394A1 (en) 2023-12-21
CN106536752B (zh) 2021-08-06
US20230407396A1 (en) 2023-12-21
EP3117012A4 (en) 2017-08-30
CN113528645A (zh) 2021-10-22
US20230399696A1 (en) 2023-12-14
AU2023208145A1 (en) 2023-08-17
AU2015229083B2 (en) 2021-06-17
US20230399694A1 (en) 2023-12-14
EP3117012B1 (en) 2019-02-20
EP3117012A1 (en) 2017-01-18
CA2970916A1 (en) 2015-09-17
ES2726650T3 (es) 2019-10-08
US20230399695A1 (en) 2023-12-14
BR112016021038B1 (pt) 2023-12-12
AU2015229083A1 (en) 2016-09-08
WO2015138997A1 (en) 2015-09-17
HRP20190759T1 (hr) 2019-06-14
PT3117012T (pt) 2019-05-30
AU2021204489A1 (en) 2021-07-29
BR112016021038A2 (pt) 2017-08-15
CN106536752A (zh) 2017-03-22
TR201907106T4 (tr) 2019-06-21
PL3117012T3 (pl) 2019-08-30
AU2021204489B2 (en) 2023-04-27
US20230407392A1 (en) 2023-12-21
SI3117012T1 (sl) 2019-07-31
US20230407395A1 (en) 2023-12-21

Similar Documents

Publication Publication Date Title
DK3117012T3 (da) Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager
DK3278041T3 (da) Automatiseret kryogent opbevaringssystem
DK3186376T3 (da) Fremgangsmåder til forbedring af cas9-medieret manipulationseffektivitet
DK3224648T3 (da) System til monitorering af et maritimt miljø
DK3207481T3 (da) Reduktion af fejl ved forudsigelse af genetiske slægtskab
DK3105252T3 (da) Bispecifikke antistoffer til anvendelse ved stamcelletransplantation
DK3113883T3 (da) Cellesorteringssystem der anvender mikrofremstillede komponenter
DK3198026T3 (da) Fremgangsmåde til bestemmelse af pik3ca-mutationsstatus i en prøve
DK3122444T3 (da) Fremgangsmåde til fremstilling af membraner
DK3196572T3 (da) Køleindretning til container
DK3345687T3 (da) Mobilt system til rengøring af en beholder
DK3125898T3 (da) Farmakofor til trail-induktion
DK3193594T3 (da) Fremgangsmåder til frembringelse af cellebank med ultrahøj densitet
IL257678A (en) Methods of stem cell transplantation
DK2983680T3 (da) Forbedring af organer til transplantation
DK3105873T3 (da) Teknik til lagring af softbits
DK3304037T3 (da) Fremgangsmåde til opsamling af cellekolonier
DK3028646T3 (da) Foldelig indretning til opsamling af en afføringsprøve
DK3190875T3 (da) Fremgangsmåder og systemer til udklækning af æg
DK3163041T3 (da) Indretning til rensning af udstødning
DK3126521T3 (da) HNF4G-RSPO2-fusionsgen
DK3230013T3 (da) Kuffert til opbevaring af værktøjer eller smådele
DK3207009T3 (da) Fremgangsmåde til fremstilling af halogensubstituerede benzener
DK3446866T3 (da) Maskine til fremstilling af beholdere
SG11201610359QA (en) Method for determining a protein-protein interaction