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DK3207481T3 - Reduktion af fejl ved forudsigelse af genetiske slægtskab - Google Patents

Reduktion af fejl ved forudsigelse af genetiske slægtskab Download PDF

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Publication number
DK3207481T3
DK3207481T3 DK15850218.7T DK15850218T DK3207481T3 DK 3207481 T3 DK3207481 T3 DK 3207481T3 DK 15850218 T DK15850218 T DK 15850218T DK 3207481 T3 DK3207481 T3 DK 3207481T3
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DK
Denmark
Prior art keywords
reducing errors
genetic relationships
predicting genetic
predicting
relationships
Prior art date
Application number
DK15850218.7T
Other languages
English (en)
Inventor
Mathew J Barber
Yong Wang
Keith D Noto
Kenneth G Chahine
Catherine Ann Ball
Original Assignee
Ancestry Com Dna Llc
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Filing date
Publication date
Application filed by Ancestry Com Dna Llc filed Critical Ancestry Com Dna Llc
Application granted granted Critical
Publication of DK3207481T3 publication Critical patent/DK3207481T3/da

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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40Population genetics; Linkage disequilibrium
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N5/00Computing arrangements using knowledge-based models
    • G06N5/04Inference or reasoning models
    • G06N5/048Fuzzy inferencing
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N7/00Computing arrangements based on specific mathematical models
    • G06N7/01Probabilistic graphical models, e.g. probabilistic networks
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B10/00ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Software Systems (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • Data Mining & Analysis (AREA)
  • Physiology (AREA)
  • General Physics & Mathematics (AREA)
  • Computing Systems (AREA)
  • Mathematical Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioethics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Ecology (AREA)
  • Automation & Control Theory (AREA)
  • Fuzzy Systems (AREA)
  • Computational Linguistics (AREA)
  • Mathematical Analysis (AREA)
  • Probability & Statistics with Applications (AREA)
  • Mathematical Optimization (AREA)
DK15850218.7T 2014-10-14 2015-10-14 Reduktion af fejl ved forudsigelse af genetiske slægtskab DK3207481T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462063849P 2014-10-14 2014-10-14
PCT/US2015/055579 WO2016061260A1 (en) 2014-10-14 2015-10-14 Reducing error in predicted genetic relationships

Publications (1)

Publication Number Publication Date
DK3207481T3 true DK3207481T3 (da) 2020-02-03

Family

ID=55747284

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15850218.7T DK3207481T3 (da) 2014-10-14 2015-10-14 Reduktion af fejl ved forudsigelse af genetiske slægtskab

Country Status (9)

Country Link
US (2) US10720229B2 (da)
EP (2) EP3207481B1 (da)
AU (1) AU2015332507B2 (da)
CA (1) CA2964780C (da)
DK (1) DK3207481T3 (da)
ES (1) ES2762942T3 (da)
MX (1) MX2017004989A (da)
PL (1) PL3207481T3 (da)
WO (1) WO2016061260A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9336177B2 (en) 2007-10-15 2016-05-10 23Andme, Inc. Genome sharing
WO2009051766A1 (en) 2007-10-15 2009-04-23 23Andme, Inc. Family inheritance
WO2010077336A1 (en) 2008-12-31 2010-07-08 23Andme, Inc. Finding relatives in a database
US8990250B1 (en) 2011-10-11 2015-03-24 23Andme, Inc. Cohort selection with privacy protection
US10437858B2 (en) 2011-11-23 2019-10-08 23Andme, Inc. Database and data processing system for use with a network-based personal genetics services platform
US10025877B2 (en) 2012-06-06 2018-07-17 23Andme, Inc. Determining family connections of individuals in a database
US9836576B1 (en) 2012-11-08 2017-12-05 23Andme, Inc. Phasing of unphased genotype data
US9213947B1 (en) 2012-11-08 2015-12-15 23Andme, Inc. Scalable pipeline for local ancestry inference
AU2015332507B2 (en) * 2014-10-14 2021-09-02 Ancestry.Com Dna, Llc Reducing error in predicted genetic relationships
MX2017004980A (es) 2014-10-17 2017-12-07 Ancestry Com Dna Llc Genomas humanos ancestrales.
MX2017006028A (es) 2014-11-06 2018-01-23 Ancestryhealth Com Llc Prediccion de resultados de salud.
AU2016293485B2 (en) * 2015-07-13 2021-05-13 Ancestry.Com Dna, Llc Local genetic ethnicity determination system
WO2018031739A1 (en) * 2016-08-10 2018-02-15 New York Genome Center, Inc. Ultra-low coverage genome sequencing and uses thereof
WO2020035821A1 (en) 2018-08-17 2020-02-20 Ancestry.Com Dna, Llc Prediction of phenotypes using recommender systems
AU2019370896A1 (en) 2018-10-31 2021-06-17 Ancestry.Com Dna, Llc Estimation of phenotypes using DNA, pedigree, and historical data
CA3147888A1 (en) 2019-07-19 2021-01-28 23Andme, Inc. Phase-aware determination of identity-by-descent dna segments
US12050629B1 (en) 2019-08-02 2024-07-30 Ancestry.Com Dna, Llc Determining data inheritance of data segments
CA3149354A1 (en) * 2019-08-02 2021-02-11 Ancestry.Com Dna, Llc Clustering of matched segments to determine linkage of dataset in a database
WO2021051018A1 (en) 2019-09-13 2021-03-18 23Andme, Inc. Methods and systems for determining and displaying pedigrees
GB2608502A (en) * 2019-11-18 2023-01-04 Embark Veterinary Inc Methods and systems for determining ancestral relatedness
US11817176B2 (en) 2020-08-13 2023-11-14 23Andme, Inc. Ancestry composition determination
EP4200858A4 (en) 2020-10-09 2024-08-28 23Andme Inc FORMATTING AND STORAGE OF GENETIC MARKERS
AU2022276402A1 (en) 2021-05-20 2024-01-18 Ancestry.Com Operations Inc. Domain knowledge guided selection of nodes for addition to data trees
WO2023281450A1 (en) 2021-07-09 2023-01-12 Ancestry.Com Operations Inc. Handwriting recognition pipelines for genealogical records
WO2023152692A1 (en) 2022-02-10 2023-08-17 Ancestry.Com Operations Inc. Determining relationships of historical data records
US20230281310A1 (en) * 2022-03-01 2023-09-07 Meta Plataforms, Inc. Systems and methods of uncertainty-aware self-supervised-learning for malware and threat detection
US20230325373A1 (en) 2022-03-15 2023-10-12 Ancestry.Com Operations Inc. Machine-learning based automated document integration into genealogical trees
WO2023200976A1 (en) 2022-04-13 2023-10-19 Ancestry.Com Dna, Llc Accelerated hidden markov models for genotype analysis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010077336A1 (en) * 2008-12-31 2010-07-08 23Andme, Inc. Finding relatives in a database
WO2011139797A2 (en) 2010-04-27 2011-11-10 Spiral Genetics Inc. Method and system for analysis and error correction of biological sequences and inference of relationship for multiple samples
WO2012099890A1 (en) * 2011-01-18 2012-07-26 University Of Utah Research Foundation Estimation of recent shared ancestry
US20140067355A1 (en) * 2012-09-06 2014-03-06 Ancestry.Com Dna, Llc Using Haplotypes to Infer Ancestral Origins for Recently Admixed Individuals
EP2973130B1 (en) 2013-03-15 2021-11-24 Ancestry.com DNA, LLC Family networks
AU2015332507B2 (en) * 2014-10-14 2021-09-02 Ancestry.Com Dna, Llc Reducing error in predicted genetic relationships
US20170213127A1 (en) * 2016-01-24 2017-07-27 Matthew Charles Duncan Method and System for Discovering Ancestors using Genomic and Genealogic Data
WO2018031739A1 (en) * 2016-08-10 2018-02-15 New York Genome Center, Inc. Ultra-low coverage genome sequencing and uses thereof
WO2019051233A1 (en) * 2017-09-07 2019-03-14 Regeneron Pharmaceuticals, Inc. SYSTEM AND METHOD FOR PREDICTING PARENTALITY IN A HUMAN POPULATION

Also Published As

Publication number Publication date
EP3207481A4 (en) 2018-04-04
US10720229B2 (en) 2020-07-21
WO2016061260A1 (en) 2016-04-21
US20200286591A1 (en) 2020-09-10
AU2015332507A1 (en) 2017-06-01
MX2017004989A (es) 2017-11-13
CA2964780A1 (en) 2016-04-21
EP3207481A1 (en) 2017-08-23
AU2015332507B2 (en) 2021-09-02
US20170220738A1 (en) 2017-08-03
EP3207481B1 (en) 2019-12-04
CA2964780C (en) 2023-03-21
EP3621080A1 (en) 2020-03-11
ES2762942T3 (es) 2020-05-26
EP3621080B1 (en) 2023-09-06
PL3207481T3 (pl) 2020-05-18
NZ731808A (en) 2021-10-29

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