DK1778867T3 - Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve - Google Patents
Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøveInfo
- Publication number
- DK1778867T3 DK1778867T3 DK05767727.0T DK05767727T DK1778867T3 DK 1778867 T3 DK1778867 T3 DK 1778867T3 DK 05767727 T DK05767727 T DK 05767727T DK 1778867 T3 DK1778867 T3 DK 1778867T3
- Authority
- DK
- Denmark
- Prior art keywords
- capture
- nucleic acid
- hairpin
- methods
- sample
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000012472 biological sample Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 7
- 238000001514 detection method Methods 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58542104P | 2004-07-01 | 2004-07-01 | |
| PCT/US2005/023555 WO2006007567A2 (en) | 2004-07-01 | 2005-06-29 | Methods and compositions to detect nucleic acids in a biological sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1778867T3 true DK1778867T3 (da) | 2010-08-02 |
Family
ID=35457287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05767727.0T DK1778867T3 (da) | 2004-07-01 | 2005-06-29 | Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8034554B2 (da) |
| EP (1) | EP1778867B1 (da) |
| JP (1) | JP5020818B2 (da) |
| AT (1) | ATE466107T1 (da) |
| AU (2) | AU2005262357B2 (da) |
| CA (1) | CA2572472C (da) |
| DE (1) | DE602005020943D1 (da) |
| DK (1) | DK1778867T3 (da) |
| WO (1) | WO2006007567A2 (da) |
Families Citing this family (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5020818B2 (ja) | 2004-07-01 | 2012-09-05 | ジェン−プローブ・インコーポレーテッド | 生物学的試料中の核酸を検出するための方法及び組成物 |
| EP1819835B1 (en) | 2004-12-08 | 2010-08-04 | Gen-Probe Incorporated | Detection of nucleic acids from multiple types of human papillomaviruses |
| US7993853B2 (en) * | 2005-05-06 | 2011-08-09 | Gen-Probe Incorporated | Methods of nucleic acid target capture |
| US8632970B2 (en) * | 2005-05-09 | 2014-01-21 | Affymetrix, Inc. | Multiplex capture of nucleic acids |
| WO2007035685A2 (en) * | 2005-09-16 | 2007-03-29 | Primera Biosystems, Inc. | Compositions and methods for purifying nucleic acids |
| US20090291431A1 (en) | 2005-10-17 | 2009-11-26 | Gen-Probe Incorporated | Compositions and methods to detect legionella pneumophila nucleic acid |
| US20070190560A1 (en) | 2006-02-13 | 2007-08-16 | Olga Ornatsky | Element-tagged olignucleotide gene expression analysis |
| AU2007249286B2 (en) * | 2006-05-12 | 2013-06-13 | Gen-Probe Incorporated | Compositions and methods to detect enterococci nucleic acid |
| EP2345740B1 (en) | 2006-06-06 | 2015-09-30 | Gen-Probe Incorporated | Tagged oligonucleotides and their use in nucleic acid amplification methods |
| US20100062436A1 (en) * | 2006-10-31 | 2010-03-11 | Noxxon Pharma Ag | Methods for Detection of a Single- or Double-Stranded Nucleic Acid Molecule |
| CN109055495A (zh) * | 2006-11-06 | 2018-12-21 | 美艾利尔技术公司 | 使用结合元件用于分析的装置和方法 |
| AU2014200826B2 (en) * | 2006-11-06 | 2016-01-14 | Clondiag Gmbh | Assays |
| AU2016202243B2 (en) * | 2006-11-06 | 2017-12-14 | Clondiag Gmbh | Assays |
| US8198027B2 (en) | 2006-12-21 | 2012-06-12 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| EP1978111B1 (en) | 2007-04-02 | 2013-03-27 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa |
| ES2717940T3 (es) * | 2007-07-23 | 2019-06-26 | Alere Tech Gmbh | Ensayos |
| US20090162845A1 (en) * | 2007-12-20 | 2009-06-25 | Elazar Rabbani | Affinity tag nucleic acid and protein compositions, and processes for using same |
| US7595164B2 (en) | 2007-12-26 | 2009-09-29 | Gen-Probe Incorporated | Compositions and methods to detect Candida albicans nucleic acid |
| US20090215050A1 (en) * | 2008-02-22 | 2009-08-27 | Robert Delmar Jenison | Systems and methods for point-of-care amplification and detection of polynucleotides |
| EP2288726B1 (en) | 2008-05-13 | 2012-06-13 | Gen-Probe Incorporated | Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences |
| US8703421B2 (en) | 2008-05-30 | 2014-04-22 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Salmonella |
| WO2010009398A1 (en) * | 2008-07-18 | 2010-01-21 | Xenomics, Inc. | Methods for pcr-based detection of "ultra short" nucleic acid sequences |
| US8399222B2 (en) | 2008-11-25 | 2013-03-19 | Gen-Probe Incorporated | Compositions and methods for detecting small RNAs, and uses thereof |
| EP2910647A1 (en) | 2008-12-30 | 2015-08-26 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of listeria |
| EP3450573B1 (en) | 2009-06-23 | 2022-01-26 | Gen-Probe Incorporated | Compositions and methods for detecting nucleic acid from mollicutes |
| CA2766391C (en) | 2009-07-01 | 2021-04-20 | Gen-Probe Incorporated | Methods and compositions for multiplex nucleic acid amplification |
| WO2011026139A1 (en) | 2009-08-31 | 2011-03-03 | Gen-Probe Incorporated | Dengue virus assay |
| EP3604558B1 (en) | 2010-02-17 | 2022-10-12 | Gen-Probe Incorporated | Compositions and methods to detect atopobium vaginae nucleic acid |
| CA3074551C (en) | 2010-04-21 | 2021-05-04 | Gen-Probe Incorporated | Compositions, methods and kits to detect herpes simplex virus nucleic acids |
| WO2012030856A2 (en) | 2010-08-30 | 2012-03-08 | Gen-Probe Incorporated | Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus |
| AU2011301804B2 (en) | 2010-09-16 | 2015-07-16 | Gen-Probe Incorporated | Capture probes immobilizable via L-nucleotide tail |
| EP2625297B1 (en) | 2010-10-04 | 2018-10-10 | Gen-Probe Prodesse, Inc. | Compositions, methods and kits to detect adenovirus nucleic acids |
| AU2011323478B2 (en) | 2010-11-01 | 2015-09-10 | Gen-Probe Incorporated | Integrated capture and amplification of target nucleic acid for sequencing |
| EP3498864B1 (en) | 2011-03-10 | 2024-10-09 | Gen-Probe Incorporated | Methods for the selection and optimization of oligonucleotide tag sequences |
| AU2012249751B2 (en) | 2011-04-25 | 2016-11-03 | Gen-Probe Incorporated | Compositions and methods for detecting BV-associated bacterial nucleic acid |
| EP2732054B1 (en) | 2011-07-15 | 2019-04-03 | Gen-Probe Incorporated | Method for detecting human parvovirus nucleic acid in single-plex or multiplex assays |
| EP3225698B1 (en) | 2011-09-06 | 2019-07-31 | Gen-Probe Incorporated | Closed nucleic acid structures |
| US9663829B2 (en) | 2011-09-08 | 2017-05-30 | Gen-Probe Incorporated | Compositions and methods for detecting BV-associated bacterial nucleic acid |
| US9175337B2 (en) | 2011-09-21 | 2015-11-03 | Gen-Probe Incorporated | Methods for amplifying nucleic acid using tag-mediated displacement |
| WO2013049135A1 (en) | 2011-09-26 | 2013-04-04 | Gen-Probe Incorporated | Algorithms for sequence determinations |
| DE102011120550B4 (de) | 2011-12-05 | 2013-11-07 | Gen-Probe Prodesse, Inc. | Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren |
| US10655165B2 (en) * | 2012-02-01 | 2020-05-19 | Gen-Probe Incorporated | Asymmetric hairpin target capture oligomers |
| AU2013205010B2 (en) | 2012-02-24 | 2016-10-20 | Gen-Probe Incorporated | Detection of Shiga toxin genes in bacteria |
| JP6196611B2 (ja) * | 2012-03-05 | 2017-09-13 | 日本碍子株式会社 | 標的核酸の検出方法 |
| AU2013205110B2 (en) | 2012-04-24 | 2016-10-13 | Gen-Probe Incorporated | Compositions, Methods and Kits to Detect Herpes Simplex Virus Nucleic Acids |
| AU2013205064B2 (en) | 2012-06-04 | 2015-07-30 | Gen-Probe Incorporated | Compositions and Methods for Amplifying and Characterizing HCV Nucleic Acid |
| EP2890814B1 (en) | 2012-08-30 | 2019-11-13 | Gen-Probe Incorporated | Multiphase nucleic acid amplification |
| AU2013205122B2 (en) | 2012-10-11 | 2016-11-10 | Gen-Probe Incorporated | Compositions and Methods for Detecting Human Papillomavirus Nucleic Acid |
| AU2013205090B2 (en) | 2012-12-07 | 2016-07-28 | Gen-Probe Incorporated | Compositions and Methods for Detecting Gastrointestinal Pathogen Nucleic Acid |
| EP2976435B1 (en) * | 2013-03-19 | 2017-10-25 | Directed Genomics, LLC | Enrichment of target sequences |
| US10047406B2 (en) | 2013-08-14 | 2018-08-14 | Gen-Probe Incorporated | Compositions and methods for detecting HEV nucleic acid |
| JP6322292B2 (ja) | 2014-02-28 | 2018-05-09 | ジェン−プローブ・インコーポレーテッド | ホルムアルデヒドを含有する液体系細胞診用保存剤中検体から核酸を単離する方法 |
| DE102015017080B3 (de) | 2014-02-28 | 2024-01-04 | Gen-Probe Incorporated | Verfahren zur Isolierung von Nukleinsäure von zytologischen Proben in flüssigen Konservierungsmitteln, die Formaldehyd enthalten |
| JP6767374B2 (ja) * | 2014-10-20 | 2020-10-14 | ジェン−プローブ・インコーポレーテッド | 赤血球溶解溶液 |
| JP6944873B2 (ja) | 2015-01-09 | 2021-10-06 | ジェン−プローブ・インコーポレーテッド | 細菌性膣症を診断するための方法および組成物 |
| US20160258938A1 (en) * | 2015-03-04 | 2016-09-08 | Headway Technologies, Inc. | Method of detecting an analyte in a sample |
| CN107429297A (zh) | 2015-03-16 | 2017-12-01 | 简·探针公司 | 用于检测细菌核酸和诊断细菌性阴道病的方法和组合物 |
| US11111549B2 (en) | 2016-01-04 | 2021-09-07 | Gen-Probe Incorporated | Methods and compositions for detecting Candida species |
| US12104206B2 (en) | 2016-02-11 | 2024-10-01 | Htg Molecular Diagnostics, Inc. | Method of direct target sequencing using nuclease protection |
| JP6584986B2 (ja) * | 2016-03-18 | 2019-10-02 | 株式会社東芝 | 核酸検出方法 |
| CA3021914C (en) | 2016-04-27 | 2024-04-30 | Gen-Probe Incorporated | Blood cell lysis reagent |
| EP3469103B1 (en) | 2016-06-10 | 2021-10-06 | Gen-Probe Incorporated | Compositions and methods for detecting zika virus nucleic acid |
| JP7167013B2 (ja) | 2016-10-19 | 2022-11-08 | ジェン－プローブ・インコーポレーテッド | Ｃ型肝炎ウイルスを検出または定量するための組成物および方法 |
| WO2018094171A1 (en) | 2016-11-21 | 2018-05-24 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying hepatitis b virus |
| EP4282985A3 (en) | 2017-03-24 | 2024-02-28 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying parainfluenza virus |
| WO2018183124A1 (en) | 2017-03-25 | 2018-10-04 | Gen-Probe Incorporated | Compositions, methods and kits to detect adenovirus, metapneumovirus and/or rhinovirus nucleic acids |
| CA3062075C (en) | 2017-05-11 | 2024-04-02 | Gen-Probe Incorporated | Compositions and methods for isolating target nucleic acids |
| WO2018226798A1 (en) | 2017-06-07 | 2018-12-13 | Gen-Probe Incorporated | Detecting babesia species nucleic acid in a sample |
| WO2018227182A2 (en) * | 2017-06-09 | 2018-12-13 | University Of Houston System | Force-modulated hybridization for visualizing nucleic acid length and function |
| US11859257B2 (en) | 2017-08-11 | 2024-01-02 | Gen-Probe Incorporated | Compositions and methods for detecting Staphylococcus aureus |
| JP7068451B2 (ja) | 2017-11-17 | 2022-05-16 | ジェン－プローブ・インコーポレーテッド | Ｃ１ｏｒｆ４３核酸を検出するための組成物および方法 |
| US11662281B2 (en) | 2017-12-13 | 2023-05-30 | Gen-Probe Incorporated | Compositions and methods for biological sample processing |
| JP2021506274A (ja) | 2017-12-15 | 2021-02-22 | ジェン−プローブ・インコーポレーテッド | 毒素産生Ｃｌｏｓｔｒｉｄｉｕｍ ｄｉｆｆｉｃｉｌｅを検出するための組成物および方法 |
| AU2019286648B2 (en) | 2018-06-13 | 2023-11-23 | Gen-Probe Incorporated | Compositions and methods for detecting group B Streptococcus nucleic acid |
| EP3830302B1 (en) | 2018-08-01 | 2022-10-05 | Gen-Probe Incorporated | Compositions and methods for detecting nucleic acids of epstein-barr virus |
| US20220074002A1 (en) * | 2018-08-21 | 2022-03-10 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus |
| AU2019324196A1 (en) | 2018-08-24 | 2021-03-18 | Gen-Probe Incorporated | Compositions and methods for detecting bacterial nucleic acid and diagnosing bacterial vaginosis |
| CN109337956B (zh) * | 2018-09-07 | 2022-08-19 | 上海思路迪生物医学科技有限公司 | 基于ngs技术富集多基因茎环探针设计方法及试剂盒 |
| CA3116895A1 (en) | 2018-10-22 | 2020-04-30 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human polyomavirus bk virus |
| TW202030333A (zh) | 2018-12-20 | 2020-08-16 | 美商簡 探針公司 | 用於檢測瘧原蟲物種核酸之組成物及方法 |
| AU2020210753A1 (en) | 2019-01-25 | 2021-09-02 | Gen-Probe Incorporated | Detection of drug-resistant mycoplasma genitalium |
| EP4407046A3 (en) | 2019-03-22 | 2024-10-16 | Gen-Probe Incorporated | Compositions and methods for detecting group a streptococcus |
| WO2020256378A1 (ko) * | 2019-06-17 | 2020-12-24 | 강릉원주대학교산학협력단 | 핵산 검출 방법 |
| JP2022540801A (ja) | 2019-07-03 | 2022-09-20 | ジェン－プローブ・インコーポレーテッド | 試料中のＴｒｉｃｈｏｍｏｎａｓ ｖａｇｉｎａｌｉｓの存在を決定する際に使用するためのオリゴヌクレオチド |
| CN116287111A (zh) | 2019-11-14 | 2023-06-23 | 简·探针公司 | 用于捕获靶核酸的组合物和方法 |
| EP4114985A1 (en) | 2020-03-04 | 2023-01-11 | Gen-Probe Incorporated | Compositions and methods for detecting sars-cov-2 nucleic acid |
| CN115698325A (zh) | 2020-05-07 | 2023-02-03 | 盖立复诊断解决方案公司 | 用于检测SARS-CoV-2核酸的方法和组合物 |
| CA3211659A1 (en) | 2021-03-15 | 2022-09-22 | Gen-Probe Incorporated | Compositions and methods for biological sample processing |
| CA3218222A1 (en) | 2021-05-14 | 2022-11-17 | Gen-Probe Incorporated | Compositions and methods for detecting human adenovirus nucleic acid |
| CA3220932A1 (en) | 2021-07-01 | 2023-01-05 | Gen-Probe Incorporated | Enzyme formulations and reaction mixtures for nucleic acid amplification |
| EP4382622A3 (en) | 2021-07-27 | 2024-08-21 | Gen-Probe Incorporated | Compositions and methods for detecting shigella and at least one of salmonella, c. jejuni, c. coli, and stec |
| CN114107446A (zh) * | 2021-12-16 | 2022-03-01 | 福建和瑞基因科技有限公司 | 一种核酸的检测试剂盒及其检测方法 |
| CN114250224B (zh) * | 2021-12-16 | 2024-02-27 | 福建和瑞基因科技有限公司 | 一种用于提取或检测样本中小分子rna的核酸组合物及其试剂盒和方法 |
| WO2024054924A1 (en) | 2022-09-08 | 2024-03-14 | Gen-Probe Incorporated | Method of detecting nucleic acid analytes using dual-specificity primers |
| WO2024081776A1 (en) | 2022-10-13 | 2024-04-18 | Gen-Probe Incorporated | Cellularity control for nucleic acid assays |
| US20240124931A1 (en) * | 2022-10-15 | 2024-04-18 | Renato Rozental | Material and method for diagnosis of traumatic brain injury |
| WO2024137379A2 (en) | 2022-12-19 | 2024-06-27 | Gen-Probe Incorporated | Compositions and methods for detecting gastrointestinal pathogens |
| WO2024161179A1 (en) | 2023-01-31 | 2024-08-08 | Mobidiag Oy | Compositions and methods for detecting stx nucleic acids |
| WO2024192338A1 (en) | 2023-03-16 | 2024-09-19 | Gen-Probe Incorporated | Compositions and methods for detecting gastrointestinal parasites |
| EP4454758A1 (en) | 2023-04-28 | 2024-10-30 | Mobidiag Oy | Nucleic acid amplification process controls |
| EP4455303A1 (en) | 2023-04-28 | 2024-10-30 | Mobidiag Oy | Nucleic acid amplification process controls |
| EP4455304A1 (en) | 2023-04-28 | 2024-10-30 | Mobidiag Oy | Nucleic acid amplification process controls |
Family Cites Families (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4174384A (en) | 1975-06-30 | 1979-11-13 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| CA1190838A (en) | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
| FI63596C (fi) | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
| US4556643A (en) | 1982-07-26 | 1985-12-03 | Agracetus | Assay method and probe for polynucleotide sequences |
| CA1260372A (en) | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Hybridization method for the detection of genetic materials |
| US6221581B1 (en) | 1984-04-27 | 2001-04-24 | Enzo Diagnostics, Inc. | Processes for detecting polynucleotides, determining genetic mutations or defects in genetic material, separating or isolating nucleic acid of interest from samples, and useful compositions of matter and multihybrid complex compositions |
| US5288609A (en) | 1984-04-27 | 1994-02-22 | Enzo Diagnostics, Inc. | Capture sandwich hybridization method and composition |
| US5268266A (en) | 1984-05-07 | 1993-12-07 | Genetics Institute, Inc. | Process and nucleic acid construct for producing reagent complexes useful in determining target nucleotide sequences |
| US4766062A (en) | 1984-05-07 | 1988-08-23 | Allied Corporation | Displacement polynucleotide assay method and polynucleotide complex reagent therefor |
| US4824776A (en) | 1985-07-25 | 1989-04-25 | Molecular Biosystems, Inc. | Method for increasing the sensitivity of nucleic acid hybridization assays |
| US4725536A (en) | 1985-09-19 | 1988-02-16 | Genetics Institute, Inc. | Reagent polynucleotide complex with multiple target binding regions, and kit and methods |
| US4752566A (en) | 1985-12-17 | 1988-06-21 | Genetics Institute, Inc. | Displacement polynucleotide method and reagent complex employing labeled probe polynucleotide |
| US4818680A (en) | 1985-12-18 | 1989-04-04 | Mary Collins | Method and kit involving displacement and rehybridization of labeled polynucleotide |
| CA1273552A (en) | 1985-12-23 | 1990-09-04 | Michael J. Heller | Fluorescent stokes shift probes for polynucleotide hybridization assays |
| ZA877772B (en) | 1986-10-23 | 1988-04-20 | Amoco Corporation | Target and background capture methods and apparatus for affinity assays |
| US5714380A (en) | 1986-10-23 | 1998-02-03 | Amoco Corporation | Closed vessel for isolating target molecules and for performing amplification |
| US5283174A (en) | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5118801A (en) | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| ES2093633T3 (es) | 1989-01-19 | 1997-01-01 | Behringwerke Ag | Amplificacion de acidos nucleicos utilizando un unico cebador. |
| AU5347690A (en) | 1989-03-10 | 1990-10-09 | Gene-Trak Systems | Preventing interference with affinity capture schemes |
| EP0463036B1 (en) | 1989-03-10 | 1995-02-22 | Amoco Corporation | Immobilized oligonucleotide probes and uses therefor |
| US5589335A (en) * | 1989-04-05 | 1996-12-31 | Amoco Corporation | Hybridization promotion reagents |
| DE69032847T2 (de) | 1989-06-30 | 1999-05-12 | Chiron Corp., Emeryville, Calif. | Hydrophobe Nukleinsäure-Sonde |
| US5439793A (en) | 1990-07-19 | 1995-08-08 | Syntex (U.S.A.) Inc. | Method for producing a polynucleotide having an intramolecularly base-paired structure |
| US5849481A (en) | 1990-07-27 | 1998-12-15 | Chiron Corporation | Nucleic acid hybridization assays employing large comb-type branched polynucleotides |
| EP0529070A1 (en) * | 1991-02-27 | 1993-03-03 | Amoco Corporation | Methods for improving the sensitivity of hybridization assays |
| US5445933A (en) | 1992-09-15 | 1995-08-29 | Boehringer Mannheim Corporation | Strand displacement assay and complex useful therefor |
| EP0601889A2 (en) | 1992-12-10 | 1994-06-15 | Maine Medical Center Research Institute | Nucleic acid probes |
| US6576419B1 (en) | 1993-07-23 | 2003-06-10 | University Of Utah Research Foundation | Assay procedure using fluorogenic tracers |
| CA2105364A1 (en) | 1993-09-01 | 1995-03-02 | Eric T. Kool | Stem-loop oligonucleotides containing parallel and antiparallel binding domains |
| US6156501A (en) | 1993-10-26 | 2000-12-05 | Affymetrix, Inc. | Arrays of modified nucleic acid probes and methods of use |
| US6129828A (en) * | 1996-09-06 | 2000-10-10 | Nanogen, Inc. | Apparatus and methods for active biological sample preparation |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US5681697A (en) | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| US5861273A (en) | 1993-12-21 | 1999-01-19 | Celtrix Phamraceuticals, Inc. | Chromosomal expression of heterologous genes in bacterial cells |
| US5631148A (en) | 1994-04-22 | 1997-05-20 | Chiron Corporation | Ribozymes with product ejection by strand displacement |
| AU2604995A (en) | 1994-06-01 | 1995-12-21 | Hybridon, Inc. | Branched oligonucleotides as pathogen-inhibitory agents |
| US5731148A (en) | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
| US5770365A (en) * | 1995-08-25 | 1998-06-23 | Tm Technologies, Inc. | Nucleic acid capture moieties |
| US5914230A (en) | 1995-12-22 | 1999-06-22 | Dade Behring Inc. | Homogeneous amplification and detection of nucleic acids |
| DE69738687D1 (de) | 1996-04-12 | 2008-06-26 | Phri Properties Inc | Sonden, kits und assays |
| US20030054376A1 (en) * | 1997-07-07 | 2003-03-20 | Mullis Kary Banks | Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus |
| JP2000514307A (ja) * | 1996-07-16 | 2000-10-31 | ジェン―プローブ・インコーポレーテッド | 増加した標的特異的ｔ▲下ｍ▼を持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法 |
| US5965363A (en) | 1996-09-19 | 1999-10-12 | Genetrace Systems Inc. | Methods of preparing nucleic acids for mass spectrometric analysis |
| US6025133A (en) | 1996-12-30 | 2000-02-15 | Gen-Probe Incorporated | Promoter-sequestered oligonucleoside and method of use |
| US6534273B2 (en) | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| CA2287570C (en) | 1997-05-02 | 2008-10-28 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| EP1025120B1 (en) | 1997-10-27 | 2010-08-18 | Boston Probes, Inc. | Methods, kits and compositions pertaining to pna molecular beacons |
| EP1092047B1 (en) * | 1998-07-02 | 2009-08-26 | Gen-Probe Incorporated | Molecular torches |
| AU5492499A (en) | 1998-08-21 | 2000-03-14 | University Of Virginia Patent Foundation | Signal generating oligonucleotide-based biosensor |
| ATE253075T1 (de) | 1998-08-27 | 2003-11-15 | Bayer Ag | Oligomerreinigung durch selektion mittels zweier enden |
| WO2000044914A1 (en) | 1999-01-28 | 2000-08-03 | Medical College Of Georgia Research Institute, Inc. | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna |
| WO2000071740A1 (en) * | 1999-05-24 | 2000-11-30 | The Public Health Research Institute Of The City Of New York, Inc. | High specificity hairpin antisense oligonucleotides |
| US7052844B2 (en) * | 1999-12-21 | 2006-05-30 | Ingeneus, Inc. | Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism |
| US7230092B2 (en) * | 2000-06-06 | 2007-06-12 | Luminex Molecular Diagnostics, Inc. | Capture moieties for nucleic acids and uses thereof |
| US6451588B1 (en) * | 2000-06-30 | 2002-09-17 | Pe Corporation (Ny) | Multipartite high-affinity nucleic acid probes |
| US6596490B2 (en) | 2000-07-14 | 2003-07-22 | Applied Gene Technologies, Inc. | Nucleic acid hairpin probes and uses thereof |
| AU2002230734A1 (en) | 2000-12-11 | 2002-06-24 | Alexion Pharmaceuticals, Inc. | Nested oligonucleotides containing hairpin for nucleic acid amplification |
| USH2220H1 (en) | 2001-08-10 | 2008-07-01 | Snp Consortium | Identification and mapping of single nucleotide polymorphisms in the human genome |
| US7371580B2 (en) * | 2001-08-24 | 2008-05-13 | Agilent Technologies, Inc. | Use of unstructured nucleic acids in assaying nucleic acid molecules |
| CA2931751A1 (en) * | 2001-11-02 | 2003-05-15 | Gen-Probe Incorporated | Compositions, methods and kits for determining the presence of mycoplasma pneumoniae and/or mycoplasma genitalium in a test sample |
| US7220544B2 (en) | 2002-05-08 | 2007-05-22 | Arkray, Inc. | Method for detecting target nucleic acid |
| US7851150B2 (en) | 2002-12-18 | 2010-12-14 | Third Wave Technologies, Inc. | Detection of small nucleic acids |
| US7741031B2 (en) | 2003-03-07 | 2010-06-22 | The Public Health Research Institute Of The City Of New York | Optically decodable microcarries, arrays and methods |
| EP2508608A1 (en) | 2003-06-09 | 2012-10-10 | Alnylam Pharmaceuticals Inc. | Method of treating neurodegenerative disease |
| US20050037362A1 (en) | 2003-08-11 | 2005-02-17 | Eppendorf Array Technologies, S.A. | Detection and quantification of siRNA on microarrays |
| JP5020818B2 (ja) | 2004-07-01 | 2012-09-05 | ジェン−プローブ・インコーポレーテッド | 生物学的試料中の核酸を検出するための方法及び組成物 |
| US20060292616A1 (en) | 2005-06-23 | 2006-12-28 | U.S. Genomics, Inc. | Single molecule miRNA-based disease diagnostic methods |
-
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- 2005-06-29 WO PCT/US2005/023555 patent/WO2006007567A2/en active Application Filing
- 2005-06-29 AT AT05767727T patent/ATE466107T1/de not_active IP Right Cessation
- 2005-06-29 EP EP05767727A patent/EP1778867B1/en not_active Not-in-force
- 2005-06-29 US US11/173,915 patent/US8034554B2/en not_active Expired - Fee Related
- 2005-06-29 DK DK05767727.0T patent/DK1778867T3/da active
- 2005-06-29 DE DE602005020943T patent/DE602005020943D1/de active Active
- 2005-06-29 CA CA2572472A patent/CA2572472C/en active Active
- 2005-06-29 AU AU2005262357A patent/AU2005262357B2/en not_active Ceased
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| US20120231551A1 (en) | 2012-09-13 |
| AU2005262357B2 (en) | 2009-10-29 |
| CA2572472C (en) | 2013-08-13 |
| EP1778867B1 (en) | 2010-04-28 |
| JP5020818B2 (ja) | 2012-09-05 |
| DE602005020943D1 (de) | 2010-06-10 |
| AU2009238261B2 (en) | 2011-11-17 |
| AU2009238261A1 (en) | 2009-12-03 |
| US8551766B2 (en) | 2013-10-08 |
| US8460869B2 (en) | 2013-06-11 |
| AU2005262357A1 (en) | 2006-01-19 |
| ATE466107T1 (de) | 2010-05-15 |
| US8034554B2 (en) | 2011-10-11 |
| JP2008504842A (ja) | 2008-02-21 |
| US20060068417A1 (en) | 2006-03-30 |
| US20110250599A1 (en) | 2011-10-13 |
| WO2006007567A3 (en) | 2006-03-30 |
| CA2572472A1 (en) | 2006-01-19 |
| WO2006007567A2 (en) | 2006-01-19 |
| EP1778867A2 (en) | 2007-05-02 |
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