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DK132174B - Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimider. - Google Patents

Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimider.

Info

Publication number
DK132174B
DK132174B DK513771AA DK513771A DK132174B DK 132174 B DK132174 B DK 132174B DK 513771A A DK513771A A DK 513771AA DK 513771 A DK513771 A DK 513771A DK 132174 B DK132174 B DK 132174B
Authority
DK
Denmark
Prior art keywords
benzylpyrimides
diamino
preparation
analogous process
analogous
Prior art date
Application number
DK513771AA
Other languages
English (en)
Other versions
DK132174C (da
Inventor
B Roth
A Stuart
T Paterson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK132174B publication Critical patent/DK132174B/da
Application granted granted Critical
Publication of DK132174C publication Critical patent/DK132174C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK513771A 1970-10-22 1971-10-21 Analogifremgangsmade til fremstilling af 2,4-diamino-5-benzylpyrimidiner DK132174C (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB963871*[A GB1375162A (da) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Publications (2)

Publication Number Publication Date
DK132174B true DK132174B (da) 1975-11-03
DK132174C DK132174C (da) 1976-03-29

Family

ID=27255400

Family Applications (1)

Application Number Title Priority Date Filing Date
DK513771A DK132174C (da) 1970-10-22 1971-10-21 Analogifremgangsmade til fremstilling af 2,4-diamino-5-benzylpyrimidiner

Country Status (20)

Country Link
JP (2) JPS5536662B1 (da)
AR (3) AR192588A1 (da)
AT (1) AT319948B (da)
BE (1) BE774281A (da)
BG (4) BG20797A3 (da)
CA (1) CA967158A (da)
CH (3) CH568301A5 (da)
DD (1) DD100877A5 (da)
DK (1) DK132174C (da)
ES (1) ES396219A1 (da)
FI (1) FI56175C (da)
FR (1) FR2111769B1 (da)
GB (1) GB1375162A (da)
IE (1) IE37452B1 (da)
IL (2) IL37984A (da)
LU (1) LU64129A1 (da)
MC (1) MC894A1 (da)
NL (1) NL175178C (da)
SE (2) SE384505B (da)
ZM (1) ZM14971A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
FR2397407A2 (fr) * 1977-07-11 1979-02-09 Dick Pierre Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides
FI791638A (fi) * 1978-05-24 1979-11-25 Wellcome Found Bensylpyrimidinkompositioner
JPS61156909A (ja) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd カレント・ミラ−回路
JPS62145907A (ja) * 1985-12-20 1987-06-30 Hitachi Ltd トランジスタ回路
ES2563952T3 (es) 2004-03-26 2016-03-16 Sumitomo Dainippon Pharma Co., Ltd. Compuesto de 8-oxoadenina 9-sustituido
EP2041135A4 (en) 2006-07-05 2010-12-01 Astrazeneca Ab As TLR7 MODULATORS, 8-OXOADENINE DERIVATIVES WORK
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
ES2373616T3 (es) 2007-03-19 2012-02-07 Astrazeneca Ab Compuestos de 8-oxo-adenina 9 sustituidos como moduladores del receptor de tipo toll (tlr7).
SI2132209T1 (sl) 2007-03-19 2014-05-30 Astrazeneca Ab Spojine 9-substituiranega-8-okso-adenina, kot modulatorji Toll-like receptorja (TLR7)
US8044056B2 (en) 2007-03-20 2011-10-25 Dainippon Sumitomo Pharma Co., Ltd. Adenine compound
PE20091236A1 (es) * 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
PE20091156A1 (es) 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
JP5913093B2 (ja) 2009-05-21 2016-04-27 アストラゼネカ アクチボラグ 新規ピリミジン誘導体と、癌とさらなる疾患の治療におけるそれらの使用
CN103370317B (zh) 2010-12-16 2015-10-07 阿斯利康(瑞典)有限公司 可用于治疗的咪唑并[4,5-c]喹啉-1-基衍生物
EP2651943B1 (en) 2010-12-17 2017-03-22 Sumitomo Dainippon Pharma Co., Ltd. Purine derivatives
AU2013261267B2 (en) 2012-05-18 2017-06-29 Sumitomo Pharma Co., Ltd. Carboxylic acid compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (da) * 1967-02-02 1968-07-30
JPS511716A (ja) * 1974-06-25 1976-01-08 Toray Industries Horiesuterumaruchifuiramentono seiho

Also Published As

Publication number Publication date
BE774281A (fr) 1972-04-21
JPS5536662B1 (da) 1980-09-22
FR2111769B1 (da) 1974-10-18
NL7114494A (da) 1972-04-25
BG20365A3 (bg) 1975-11-05
IL45422A (en) 1976-03-31
CH582681A5 (da) 1976-12-15
NL175178C (nl) 1984-10-01
GB1375162A (da) 1974-11-27
ZM14971A1 (en) 1972-07-21
IE37452B1 (en) 1977-08-03
DK132174C (da) 1976-03-29
BG20364A3 (bg) 1975-11-05
CH568301A5 (da) 1975-10-31
AR192802A1 (es) 1973-03-14
FR2111769A1 (da) 1972-06-09
LU64129A1 (da) 1972-06-28
BG20797A3 (bg) 1975-12-20
IL37984A (en) 1976-03-31
IL37984A0 (en) 1971-12-29
JPS53135991A (en) 1978-11-28
SE409705B (sv) 1979-09-03
IE37452L (en) 1972-04-22
AT319948B (de) 1975-01-10
SE384505B (sv) 1976-05-10
DD100877A5 (da) 1973-10-12
NL175178B (nl) 1984-05-01
CA967158A (en) 1975-05-06
AR192803A1 (es) 1973-03-14
CH568302A5 (da) 1975-10-31
AR192588A1 (es) 1973-02-28
FI56175B (fi) 1979-08-31
ES396219A1 (es) 1975-09-16
FI56175C (fi) 1979-12-10
MC894A1 (fr) 1972-06-22
BG21406A3 (bg) 1976-05-20

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