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FR2397407A2 - Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides - Google Patents

Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides

Info

Publication number
FR2397407A2
FR2397407A2 FR7722323A FR7722323A FR2397407A2 FR 2397407 A2 FR2397407 A2 FR 2397407A2 FR 7722323 A FR7722323 A FR 7722323A FR 7722323 A FR7722323 A FR 7722323A FR 2397407 A2 FR2397407 A2 FR 2397407A2
Authority
FR
France
Prior art keywords
sulfamids
association
solution
pyrimidine derivatives
diamino pyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7722323A
Other languages
English (en)
Other versions
FR2397407B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DICK PIERRE
Original Assignee
DICK PIERRE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DICK PIERRE filed Critical DICK PIERRE
Priority to FR7722323A priority Critical patent/FR2397407A2/fr
Priority to DE19782829820 priority patent/DE2829820A1/de
Priority to US05/922,845 priority patent/US4232023A/en
Priority to IE1377/78A priority patent/IE47232B1/en
Priority to NL7807440A priority patent/NL7807440A/xx
Priority to LU79949A priority patent/LU79949A1/fr
Priority to AT496978A priority patent/AT362381B/de
Priority to JP8449678A priority patent/JPS5448776A/ja
Priority to IT25569/78A priority patent/IT1096690B/it
Priority to ZA00783957A priority patent/ZA783957B/xx
Priority to BE2057136A priority patent/BE868893A/fr
Priority to AU37933/78A priority patent/AU3793378A/en
Priority to GB7829439A priority patent/GB2001965B/en
Publication of FR2397407A2 publication Critical patent/FR2397407A2/fr
Application granted granted Critical
Publication of FR2397407B2 publication Critical patent/FR2397407B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La présente addition décrit des dérivés mono-substitués de 2,4-diamino pyrimidines et perfectionne l'invention faisant l'objet du brevet principal 76/22162. Ces dérivés répondent à la formule suivante :
FR7722323A 1977-07-11 1977-07-11 Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides Granted FR2397407A2 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR7722323A FR2397407A2 (fr) 1977-07-11 1977-07-11 Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides
DE19782829820 DE2829820A1 (de) 1977-07-11 1978-07-06 2,4-diamino-pyrimidinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
US05/922,845 US4232023A (en) 1977-07-11 1978-07-07 Novel soluble derivatives of 2,4-diamino pyrimidine
NL7807440A NL7807440A (nl) 1977-07-11 1978-07-10 Derivaten van 2,4 - diamino -5- benzyl-pyrimidine; werkwijze voor de bereiding daarvan; geneesmiddel dat dergelijke verbindingen bevat.
LU79949A LU79949A1 (fr) 1977-07-11 1978-07-10 Nouveaux derives solubles de 2,4-diamino-pyrimidines,leur preparation et leur utilisation en tant que medicaments
AT496978A AT362381B (de) 1977-07-11 1978-07-10 Verfahren zur herstellung von neuen 2,4-diamino -pyrimidinderivaten und von deren alkalimetall- salzen
IE1377/78A IE47232B1 (en) 1977-07-11 1978-07-10 Soluble derivatives of 2,4-diamino-pyrimidines
IT25569/78A IT1096690B (it) 1977-07-11 1978-07-11 Diammino-benzil-pirimidine solubili
ZA00783957A ZA783957B (en) 1977-07-11 1978-07-11 Novel soluble derivatives of 2,4-diamino pyrimidine
BE2057136A BE868893A (fr) 1977-07-11 1978-07-11 Nouveaux derives solubles de 2,4-diaminopyrimidines, leur preparation et leur utilisation en tant que medicaments
AU37933/78A AU3793378A (en) 1977-07-11 1978-07-11 Soluble derivatives of 2, 4-diamino pyrimidine
GB7829439A GB2001965B (en) 1977-07-11 1978-07-11 Soluble derivatives of 2,4-diaminopyrimidines
JP8449678A JPS5448776A (en) 1977-07-11 1978-07-11 2*44diaminopyrimidine derivative*its manufacture and medicine as active component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7722323A FR2397407A2 (fr) 1977-07-11 1977-07-11 Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides

Publications (2)

Publication Number Publication Date
FR2397407A2 true FR2397407A2 (fr) 1979-02-09
FR2397407B2 FR2397407B2 (fr) 1980-01-04

Family

ID=9193583

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7722323A Granted FR2397407A2 (fr) 1977-07-11 1977-07-11 Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides

Country Status (13)

Country Link
US (1) US4232023A (fr)
JP (1) JPS5448776A (fr)
AT (1) AT362381B (fr)
AU (1) AU3793378A (fr)
BE (1) BE868893A (fr)
DE (1) DE2829820A1 (fr)
FR (1) FR2397407A2 (fr)
GB (1) GB2001965B (fr)
IE (1) IE47232B1 (fr)
IT (1) IT1096690B (fr)
LU (1) LU79949A1 (fr)
NL (1) NL7807440A (fr)
ZA (1) ZA783957B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502152A1 (fr) * 1981-03-20 1982-09-24 Panmedica Laboratoires Nouveaux derives solubles n2 substitues de la diamino-2,4-benzyl-5-pyrimidines, leur procede de preparation et medicaments les contenant

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6583148B1 (en) 1999-04-08 2003-06-24 Krenitsky Pharmaceuticals, Inc. Neurotrophic substituted pyrimidines
AU2001273574A1 (en) 2000-07-24 2002-02-05 Krenitsky Pharmaceuticals Inc. Substituted 5-alkynyl pyrimidines having neurotrophic activity
EP2343282B1 (fr) * 2004-03-05 2015-07-22 F. Hoffmann-La Roche AG Diaminopyrimidines en tant qu'antagonistes P2X3 et P2X2/3
CN101296907B (zh) * 2005-09-01 2013-03-27 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类
EP1924566B1 (fr) * 2005-09-01 2016-01-13 F.Hoffmann-La Roche Ag Diaminopyrimidines comme modulateurs p2x3 et p2x2/3
AU2006286576B2 (en) * 2005-09-01 2012-06-14 F. Hoffmann-La Roche Ag Diaminopyrimidines as P2X3 and P3X2/3 modulators
HUE044398T2 (hu) * 2007-10-08 2019-10-28 Medicines For Malaria Venture Mmv Flexibilis oldalláncokat tartalmazó maláriaellenes vegyületek
US9000003B2 (en) * 2011-03-10 2015-04-07 National Science And Technology Development Agency Anti-folate antimalarials with dual-binding modes and their preparation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2287071A (en) * 1938-08-08 1942-06-23 Parke Davis & Co Organic amine derivatives and method of obtaining same
US2374791A (en) * 1942-06-22 1945-05-01 Parke Davis & Co Organic amine derivatives and method of obtaining same
FR2111769A1 (fr) * 1970-10-22 1972-06-09 Wellcome Found
FR2161709A5 (fr) * 1971-11-20 1973-07-06 Knapsack Ag

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3111521A (en) * 1962-04-25 1963-11-19 Parke Davis & Co 2-aryl-nu-(polyamino-5-pyrimidinyl)-glycinonitriles

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2287071A (en) * 1938-08-08 1942-06-23 Parke Davis & Co Organic amine derivatives and method of obtaining same
US2374791A (en) * 1942-06-22 1945-05-01 Parke Davis & Co Organic amine derivatives and method of obtaining same
FR2111769A1 (fr) * 1970-10-22 1972-06-09 Wellcome Found
FR2161709A5 (fr) * 1971-11-20 1973-07-06 Knapsack Ag

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502152A1 (fr) * 1981-03-20 1982-09-24 Panmedica Laboratoires Nouveaux derives solubles n2 substitues de la diamino-2,4-benzyl-5-pyrimidines, leur procede de preparation et medicaments les contenant
EP0061397A1 (fr) * 1981-03-20 1982-09-29 S.A. PANMEDICA Société dite: Nouveaux dérivés solubles N2 substitués de la diamino-2,4-benzyl-5-pyrimidines, leur procédé de préparation et médicaments les contenant

Also Published As

Publication number Publication date
IE781377L (en) 1979-01-11
NL7807440A (nl) 1979-01-15
IT7825569A0 (it) 1978-07-11
GB2001965A (en) 1979-02-14
ATA496978A (de) 1980-10-15
JPS5448776A (en) 1979-04-17
IE47232B1 (en) 1984-01-25
IT1096690B (it) 1985-08-26
LU79949A1 (fr) 1979-04-09
DE2829820A1 (de) 1979-02-01
US4232023A (en) 1980-11-04
AU3793378A (en) 1980-01-17
ZA783957B (en) 1979-09-26
GB2001965B (en) 1982-03-10
FR2397407B2 (fr) 1980-01-04
BE868893A (fr) 1979-01-11
AT362381B (de) 1981-05-11

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