DK1297017T3 - Sammensætninger og fremgangsmåder med monoklonale og polyklonale antistoffer, der er specifikke for T-cellesubpopulationer - Google Patents
Sammensætninger og fremgangsmåder med monoklonale og polyklonale antistoffer, der er specifikke for T-cellesubpopulationerInfo
- Publication number
- DK1297017T3 DK1297017T3 DK01946572.3T DK01946572T DK1297017T3 DK 1297017 T3 DK1297017 T3 DK 1297017T3 DK 01946572 T DK01946572 T DK 01946572T DK 1297017 T3 DK1297017 T3 DK 1297017T3
- Authority
- DK
- Denmark
- Prior art keywords
- monoclonal
- compositions
- methods
- polyclonal antibodies
- antibodies specific
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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- A61K40/19—Dendritic cells
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- A—HUMAN NECESSITIES
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- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4202—Receptors, cell surface antigens or cell surface determinants
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4202—Receptors, cell surface antigens or cell surface determinants
- A61K40/421—Immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- C—CHEMISTRY; METALLURGY
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/58—Prostate
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- A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/515—CD3, T-cell receptor complex
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21246600P | 2000-06-19 | 2000-06-19 | |
PCT/US2001/019670 WO2001098357A2 (en) | 2000-06-19 | 2001-06-19 | Compositions and methods of monoclonal and polyclonal antibodies specific for t cell subpopulations |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1297017T3 true DK1297017T3 (da) | 2012-09-17 |
Family
ID=22791141
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01946572.3T DK1297017T3 (da) | 2000-06-19 | 2001-06-19 | Sammensætninger og fremgangsmåder med monoklonale og polyklonale antistoffer, der er specifikke for T-cellesubpopulationer |
DK10012392.6T DK2336187T3 (da) | 2000-06-19 | 2001-06-19 | Sammensætninger og fremgangsmåder med monoklonale og polyklonale antistoffer, der er specifikke for T-cellesubpopulationer |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10012392.6T DK2336187T3 (da) | 2000-06-19 | 2001-06-19 | Sammensætninger og fremgangsmåder med monoklonale og polyklonale antistoffer, der er specifikke for T-cellesubpopulationer |
Country Status (10)
Country | Link |
---|---|
US (4) | US20020164331A1 (da) |
EP (2) | EP1297017B1 (da) |
JP (2) | JP5184732B2 (da) |
AU (1) | AU2001268599A1 (da) |
CA (1) | CA2413866C (da) |
DK (2) | DK1297017T3 (da) |
ES (2) | ES2389645T3 (da) |
HK (2) | HK1158219A1 (da) |
PT (1) | PT1297017E (da) |
WO (1) | WO2001098357A2 (da) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004532625A (ja) * | 2000-10-24 | 2004-10-28 | ホワイトヘッド インスチチュート フォアー バイオメディカル リサーチ | 多種多様な病原体に対する樹状細胞の応答 |
IL140537A0 (en) * | 2000-12-25 | 2002-02-10 | Hadasit Med Res Service | Educated nk t cells and their uses in the treatment of immune-related disorders |
EP1372668B1 (en) | 2001-03-26 | 2011-12-07 | Dana-Farber Cancer Institute, Inc. | Method of attenuating reactions to skin irritants |
WO2003061590A2 (en) * | 2002-01-23 | 2003-07-31 | Cel-Sci Corporation | Peptide constructs for treating disease |
MXPA04007426A (es) * | 2002-02-01 | 2004-10-11 | Schering Corp | Usos de citosina de mamifero; reactivos relacionados. |
WO2003092615A2 (en) * | 2002-05-01 | 2003-11-13 | Beth Israel Deaconess Medical Center | Use of anti-cd1 antibodies for the modulation of immune responses |
EP1503795A4 (en) * | 2002-05-02 | 2009-01-21 | Univ Connecticut Health Ct | USE OF STRESS PROTEINS TO IMPROVE THE EFFICIENCY OF THERAPEUTIC ANTIBODIES |
US20050084967A1 (en) | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
US20050069546A1 (en) * | 2003-09-30 | 2005-03-31 | Yaron Ilan | Educated NKT cells and their uses in the treatment of immune-related disorders |
TWI382843B (zh) | 2004-10-07 | 2013-01-21 | Argos Therapeutics Inc | 成熟樹突細胞組合物及培養彼等之方法 |
US8513008B2 (en) * | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
JP4948418B2 (ja) | 2004-11-02 | 2012-06-06 | ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | Nkt細胞を抑制するための方法 |
DK1848813T3 (da) * | 2005-01-28 | 2013-07-15 | Univ Brigham Young | Aktivering af bakterielt glycolipid fra CD1D-begrænsede NKT-celler |
US7837990B2 (en) * | 2005-03-28 | 2010-11-23 | The Rockefeller University | In vivo expanded NKT cells and methods of use thereof |
EP2600716A4 (en) * | 2010-08-03 | 2014-02-19 | Beth Israel Hospital | METHOD AND COMPOSITIONS FOR THE TREATMENT OF METABOLISM DISEASES |
TR201909840T4 (tr) | 2011-03-11 | 2019-07-22 | Beth Israel Deaconess Medical Ct Inc | Anti-CD40 antikorları ve kullanımları. |
JP2015502340A (ja) * | 2011-10-27 | 2015-01-22 | エヌケーティー セラピューティクス インコーポレーテッドNkt Therapeutics Inc. | iNKTに対するヒト化抗体 |
CN104870011A (zh) * | 2011-11-03 | 2015-08-26 | 托莱拉医疗股份有限公司 | 选择性抑制t细胞应答的抗体和方法 |
US20130273089A1 (en) | 2011-11-03 | 2013-10-17 | Tolera Therapeutics, Inc. | Antibody and methods for selective inhibition of t-cell responses |
GB201121308D0 (en) | 2011-12-12 | 2012-01-25 | Cell Medica Ltd | Process |
JP6081483B2 (ja) | 2011-12-12 | 2017-02-15 | セル・メディカ・リミテッド | T細胞を増殖させるプロセス |
EP3591047B1 (en) | 2012-02-09 | 2022-08-03 | Baylor College of Medicine | Pepmixes to generate multiviral ctls with broad specificity |
EP2906576B1 (en) | 2012-10-12 | 2019-09-11 | The Brigham and Women's Hospital, Inc. | Glycosphingolipids and methods of use thereof |
EP3250608B1 (en) | 2015-01-27 | 2024-08-21 | LAVA Therapeutics N.V. | Single domain antibodies targeting cd1d |
BR112018004296B1 (pt) | 2015-09-04 | 2020-05-05 | Primatope Therapeutics Inc | anticorpos anti-cd40 humanizados e usos dos mesmos |
IL298359A (en) | 2015-09-18 | 2023-01-01 | Baylor College Medicine | Immunogenic detection of antigen from a pathogen and adjustment of effective clinical treatment |
CA3032949A1 (en) * | 2016-08-09 | 2018-02-15 | Angimmune, Llc | Treatment of cancer using a combination of immunomodulation and check point inhibitors |
CN107557333B (zh) * | 2017-10-16 | 2018-07-31 | 北京鼎成肽源生物技术有限公司 | 一种用于细胞治疗的新抗原呈递细胞的制备方法 |
BR112021005184A8 (pt) | 2018-09-19 | 2022-08-16 | Lava Therapeutics B V | Imunoglobulina cd1d de dupla ação |
JOP20210298A1 (ar) | 2019-05-14 | 2023-01-30 | Provention Bio Inc | طرق وتركيبات للوقاية من مرض السكري من النوع الأول |
JP7590430B2 (ja) * | 2019-11-14 | 2024-11-26 | マレンゴ・セラピューティクス,インコーポレーテッド | 抗tcr抗体分子およびその使用 |
JP2023530109A (ja) | 2020-06-11 | 2023-07-13 | プロヴェンション・バイオ・インコーポレイテッド | 1型糖尿病を予防するための方法および組成物 |
CA3200571A1 (en) * | 2020-11-06 | 2022-05-12 | National Center Of Neurology And Psychiatry | Therapeutic agent for progressive disease caused by increase in eomes-positive cd4-positive t cells |
Family Cites Families (5)
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US5853737A (en) * | 1992-12-10 | 1998-12-29 | Brigham And Women's Hospital | Method for inducing a CD1-restricted immune response |
US7119248B1 (en) * | 1994-04-12 | 2006-10-10 | Miltenyi Biotec Gmbh | Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof |
US20020068301A1 (en) * | 1997-05-28 | 2002-06-06 | Hung-Sen Lai | Cyclic peptide libraries and methods of use thereof to identify binding motifs |
US6162609A (en) * | 1997-12-31 | 2000-12-19 | The Brigham And Women's Hospital, Inc. | Diagnostic and therapeutic methods based upon Vα24JαQT cells |
DE19905048A1 (de) * | 1999-02-08 | 2000-08-10 | Gsf Forschungszentrum Umwelt | Verwendung depletorisch oder mitogen wirkender Antikörper in der Immuntherapie |
-
2001
- 2001-06-19 DK DK01946572.3T patent/DK1297017T3/da active
- 2001-06-19 ES ES01946572T patent/ES2389645T3/es not_active Expired - Lifetime
- 2001-06-19 PT PT01946572T patent/PT1297017E/pt unknown
- 2001-06-19 EP EP01946572A patent/EP1297017B1/en not_active Expired - Lifetime
- 2001-06-19 WO PCT/US2001/019670 patent/WO2001098357A2/en active Application Filing
- 2001-06-19 DK DK10012392.6T patent/DK2336187T3/da active
- 2001-06-19 CA CA2413866A patent/CA2413866C/en not_active Expired - Fee Related
- 2001-06-19 US US09/885,768 patent/US20020164331A1/en not_active Abandoned
- 2001-06-19 ES ES10012392.6T patent/ES2586206T3/es not_active Expired - Lifetime
- 2001-06-19 JP JP2002504312A patent/JP5184732B2/ja not_active Expired - Fee Related
- 2001-06-19 AU AU2001268599A patent/AU2001268599A1/en not_active Abandoned
- 2001-06-19 EP EP10012392.6A patent/EP2336187B8/en not_active Expired - Lifetime
-
2003
- 2003-09-29 HK HK11112455.0A patent/HK1158219A1/zh not_active IP Right Cessation
- 2003-09-29 HK HK03107015.3A patent/HK1054949A1/xx not_active IP Right Cessation
-
2006
- 2006-10-02 US US11/541,958 patent/US8138314B2/en not_active Expired - Fee Related
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2012
- 2012-03-19 US US13/423,683 patent/US20120258040A1/en not_active Abandoned
- 2012-07-05 JP JP2012151382A patent/JP2013014587A/ja active Pending
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2014
- 2014-09-24 US US14/495,502 patent/US20150299320A1/en not_active Abandoned
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WO2001098357A2 (en) | 2001-12-27 |
DK2336187T3 (da) | 2016-08-22 |
US8138314B2 (en) | 2012-03-20 |
EP2336187A3 (en) | 2012-01-11 |
JP2004501165A (ja) | 2004-01-15 |
EP2336187B1 (en) | 2016-05-04 |
HK1158219A1 (zh) | 2012-07-13 |
ES2586206T3 (es) | 2016-10-13 |
CA2413866A1 (en) | 2001-12-27 |
HK1054949A1 (en) | 2003-12-19 |
AU2001268599A1 (en) | 2002-01-02 |
EP1297017B1 (en) | 2012-06-13 |
ES2389645T3 (es) | 2012-10-30 |
EP1297017A2 (en) | 2003-04-02 |
US20120258040A1 (en) | 2012-10-11 |
CA2413866C (en) | 2014-09-02 |
EP2336187B8 (en) | 2016-07-06 |
JP2013014587A (ja) | 2013-01-24 |
WO2001098357A3 (en) | 2003-01-03 |
JP5184732B2 (ja) | 2013-04-17 |
US20150299320A1 (en) | 2015-10-22 |
PT1297017E (pt) | 2012-09-04 |
US20020164331A1 (en) | 2002-11-07 |
US20070160600A1 (en) | 2007-07-12 |
EP2336187A2 (en) | 2011-06-22 |
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