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DK0906567T3 - Method for removing hemoglobin interferences by albumin determination - Google Patents

Method for removing hemoglobin interferences by albumin determination

Info

Publication number
DK0906567T3
DK0906567T3 DK97927108T DK97927108T DK0906567T3 DK 0906567 T3 DK0906567 T3 DK 0906567T3 DK 97927108 T DK97927108 T DK 97927108T DK 97927108 T DK97927108 T DK 97927108T DK 0906567 T3 DK0906567 T3 DK 0906567T3
Authority
DK
Denmark
Prior art keywords
measuring
albumin
signal
wave length
determination
Prior art date
Application number
DK97927108T
Other languages
Danish (da)
Inventor
Ralph Weisheit
Barbara Boehringer Man Masters
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19622091A external-priority patent/DE19622091A1/en
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Application granted granted Critical
Publication of DK0906567T3 publication Critical patent/DK0906567T3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6827—Total protein determination, e.g. albumin in urine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to a process for determination of albumin in a sample containing free haemoglobin by optical measurement at at least two wave lengths. According to said process, (a) a measuring signal which is sufficiently high for determination is provided at a first measuring wave length; (b) (i) no measuring signal for albumin or (ii) a measuring signal for the albumin is provided at a second measuring wave length, said signal being smaller in comparison with the measuring signal at the first measuring wave length; and (c) at the first and the second measuring wave length a comparatively high interfering signal which is produced by reaction of haemoglobin with the test reagent used to determine albumin, and which changes in relation to time.
DK97927108T 1996-05-31 1997-06-02 Method for removing hemoglobin interferences by albumin determination DK0906567T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19622091A DE19622091A1 (en) 1996-05-31 1996-05-31 Accurate measurement of albumin in solution also containing haemoglobin
US4799797P 1997-05-28 1997-05-28
PCT/EP1997/002862 WO1997045728A1 (en) 1996-05-31 1997-06-02 Process to eliminate haemoglobin errors during the determination of albumin

Publications (1)

Publication Number Publication Date
DK0906567T3 true DK0906567T3 (en) 2001-04-17

Family

ID=26026235

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97927108T DK0906567T3 (en) 1996-05-31 1997-06-02 Method for removing hemoglobin interferences by albumin determination

Country Status (15)

Country Link
EP (1) EP0906567B1 (en)
JP (1) JP2000512381A (en)
KR (1) KR20000016035A (en)
CN (1) CN1214770A (en)
AT (1) ATE199781T1 (en)
AU (1) AU3171797A (en)
CA (1) CA2255855C (en)
CZ (1) CZ27198A3 (en)
DK (1) DK0906567T3 (en)
ES (1) ES2155690T3 (en)
HU (1) HUP9900723A2 (en)
IL (1) IL127276A0 (en)
NZ (1) NZ332629A (en)
PL (1) PL330221A1 (en)
WO (1) WO1997045728A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19846301A1 (en) 1998-10-08 2000-04-13 Roche Diagnostics Gmbh Optical assay for determining alkaline phosphatase in samples uses specified primary and secondary measurement wavelengths
DE19846300A1 (en) 1998-10-08 2000-04-13 Roche Diagnostics Gmbh Optical assay for determining alkaline phosphatase in samples uses a specified primary measurement wavelength in combination with a rate blank correction
EP2657681A1 (en) * 2012-04-26 2013-10-30 Roche Diagnostics GmbH Improvement of the sensitivity and the dynamic range of photometric assays by generating multiple calibration curves

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6350743A (en) * 1986-08-20 1988-03-03 Hitachi Ltd Analysis of hemolyzed blood specimen
JPH0635982B2 (en) * 1987-01-07 1994-05-11 株式会社島津製作所 Sensitive assay for antigen-antibody reaction
US5284777A (en) * 1991-03-04 1994-02-08 Isolab, Inc. Combined glycated hemoglobin and immunoturbidometric glycated albumin assay from whole blood lysate
JPH07294519A (en) * 1994-03-04 1995-11-10 Kyoto Daiichi Kagaku:Kk Measurement of component in urine
DE4427492A1 (en) * 1994-08-03 1996-02-08 Boehringer Mannheim Gmbh Method for analyzing a medical sample while avoiding interference from hemolysis

Also Published As

Publication number Publication date
EP0906567B1 (en) 2001-03-14
CA2255855C (en) 2005-10-11
EP0906567A1 (en) 1999-04-07
CN1214770A (en) 1999-04-21
KR20000016035A (en) 2000-03-25
JP2000512381A (en) 2000-09-19
HUP9900723A2 (en) 1999-07-28
IL127276A0 (en) 1999-09-22
AU3171797A (en) 1998-01-05
CA2255855A1 (en) 1997-12-04
ES2155690T3 (en) 2001-05-16
NZ332629A (en) 1999-11-29
CZ27198A3 (en) 1998-07-15
WO1997045728A1 (en) 1997-12-04
PL330221A1 (en) 1999-05-10
ATE199781T1 (en) 2001-03-15

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