DK0943326T4 - Pulveragtigt præparat til nasal administration - Google Patents
Pulveragtigt præparat til nasal administrationInfo
- Publication number
- DK0943326T4 DK0943326T4 DK97905398T DK97905398T DK0943326T4 DK 0943326 T4 DK0943326 T4 DK 0943326T4 DK 97905398 T DK97905398 T DK 97905398T DK 97905398 T DK97905398 T DK 97905398T DK 0943326 T4 DK0943326 T4 DK 0943326T4
- Authority
- DK
- Denmark
- Prior art keywords
- water
- absorbing
- base material
- drug
- gel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3955396 | 1996-02-27 | ||
JP4107996 | 1996-02-28 | ||
PCT/JP1997/000541 WO1997031626A1 (fr) | 1996-02-27 | 1997-02-26 | Composition pulverulente destinee a une adminstration nasale |
Publications (2)
Publication Number | Publication Date |
---|---|
DK0943326T3 DK0943326T3 (da) | 2003-12-08 |
DK0943326T4 true DK0943326T4 (da) | 2007-01-22 |
Family
ID=26378964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97905398T DK0943326T4 (da) | 1996-02-27 | 1997-02-26 | Pulveragtigt præparat til nasal administration |
Country Status (13)
Country | Link |
---|---|
US (3) | US6881423B2 (da) |
EP (1) | EP0943326B2 (da) |
JP (1) | JP3634380B2 (da) |
KR (1) | KR100568436B1 (da) |
CN (1) | CN1155368C (da) |
AT (1) | ATE247456T1 (da) |
AU (1) | AU722319B2 (da) |
CA (1) | CA2247191C (da) |
DE (1) | DE69724272T3 (da) |
DK (1) | DK0943326T4 (da) |
ES (1) | ES2205177T5 (da) |
PT (1) | PT943326E (da) |
WO (1) | WO1997031626A1 (da) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0943326T4 (da) * | 1996-02-27 | 2007-01-22 | Teijin Ltd | Pulveragtigt præparat til nasal administration |
TWI243687B (en) | 1998-04-21 | 2005-11-21 | Teijin Ltd | Pharmaceutical composition for application to mucosa |
EP1025859B1 (en) * | 1998-08-26 | 2006-06-28 | Teijin Limited | Powdery pernasal compositions |
ES2252993T3 (es) * | 1998-12-09 | 2006-05-16 | Chiron Corporation | Administracion de agentes neurotroficos al sistema nervioso central. |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
AR026073A1 (es) | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica acuosa que contiene ciclesonida |
AU2002218503B2 (en) * | 2000-11-29 | 2006-09-28 | Ils Inc. | Powdery preparations and methods for producing the same |
GB2378383A (en) * | 2001-06-06 | 2003-02-12 | Gursharan Moonga | Nasal delivery of pharmaceutical compositions in powder form |
US6906027B2 (en) | 2001-07-05 | 2005-06-14 | Translational Research Ltd. | Composition for nasal administration of insulin |
CA2468250A1 (en) * | 2001-11-26 | 2003-06-05 | Daiichi Suntory Pharma Co., Ltd. | Pharmaceutical composition for nasal absorption |
ES2425392T3 (es) | 2002-03-20 | 2013-10-15 | Mannkind Corporation | Cartucho para un aparato de inhalación |
GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
US20080260838A1 (en) * | 2003-08-01 | 2008-10-23 | Mannkind Corporation | Glucagon-like peptide 1 (glp-1) pharmaceutical formulations |
US7714011B2 (en) * | 2002-09-13 | 2010-05-11 | Zicam, Llc | Compositions to reduce congestion and methods for application thereof to the nasal membrane |
WO2004073729A1 (ja) | 2003-02-21 | 2004-09-02 | Translational Research Ltd. | 薬物の経鼻投与用組成物 |
WO2004084859A2 (en) | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
CN1758930B (zh) | 2003-03-27 | 2010-06-09 | 株式会社新日本科学 | 鼻腔用粉末药剂喷药装置 |
GB0315632D0 (en) | 2003-07-04 | 2003-08-13 | West Pharm Serv Drug Res Ltd | Pharmaceutical formulations |
JP4922762B2 (ja) * | 2004-08-10 | 2012-04-25 | 株式会社新日本科学 | 速効性でかつ高い吸収性を可能とする経鼻投与用組成物 |
PL1786784T3 (pl) | 2004-08-20 | 2011-04-29 | Mannkind Corp | Kataliza syntezy diketopiperazyn |
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US7115561B2 (en) * | 2004-09-22 | 2006-10-03 | Patterson James A | Medicament composition and method of administration |
GB2420707A (en) * | 2004-10-11 | 2006-06-07 | Nasaleze Patents Ltd | Compositions for intranasal administration |
US8202550B2 (en) | 2004-10-11 | 2012-06-19 | Nasaleze Ppm Limited | Compositions for intranasal administration |
PL1824450T3 (pl) * | 2004-10-11 | 2013-04-30 | Nasaleze Patents Ltd | Kompozycje do podawania donosowego |
WO2007022345A2 (en) * | 2005-08-17 | 2007-02-22 | Fleming And Company, Pharmaceuticals | Vitamin b12 nasal spray and method of use |
EP2056800B1 (en) | 2005-08-26 | 2015-12-09 | The Board Of Trustees Of The Leland Stanford Junior University | Therapy procedure for drug delivery for trigeminal pain |
ES2640282T3 (es) | 2005-09-14 | 2017-11-02 | Mannkind Corporation | Método de formulación de fármacos basado en el aumento de la afinidad de superficies de micropartículas cristalinas para agentes activos |
CA2643464C (en) | 2006-02-22 | 2018-09-04 | Mannkind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
CN101668544B (zh) | 2006-12-26 | 2013-04-24 | 株式会社新日本科学 | 经鼻投用制剂 |
AU2008316634B2 (en) * | 2007-10-24 | 2014-02-27 | Mannkind Corporation | Method of preventing adverse effects by GLP-1 |
WO2011163272A1 (en) | 2010-06-21 | 2011-12-29 | Mannkind Corporation | Dry powder drug delivery system and methods |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
IL279542B2 (en) | 2008-06-13 | 2023-10-01 | Mannkind Corp | Dry powder inhaler and drug delivery system |
EP2300083B1 (en) | 2008-06-20 | 2013-05-22 | MannKind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
PL2405963T3 (pl) | 2009-03-11 | 2014-04-30 | Mannkind Corp | Urządzenie, układ i sposób pomiaru oporu inhalatora |
WO2010131486A1 (en) * | 2009-05-15 | 2010-11-18 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal pharmaceutical compositions with improved pharmacokinetics |
AU2010259943C1 (en) | 2009-06-12 | 2016-03-03 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
WO2011013003A2 (en) * | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
ES2533987T3 (es) * | 2009-09-02 | 2015-04-16 | Nippon Soda Co., Ltd. | Partículas de hidroxipropil celulosa |
EP2298286B8 (en) * | 2009-09-18 | 2017-08-09 | SiTec PharmaBio SL | Process for dewatering of product powders |
CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
EP2548566B1 (en) | 2010-03-19 | 2018-02-21 | Daiichi Sankyo Company, Limited | Composition for transnasal administration and method for producing same |
SG194034A1 (en) | 2011-04-01 | 2013-11-29 | Mannkind Corp | Blister package for pharmaceutical cartridges |
SE536091C2 (sv) | 2011-04-14 | 2013-04-30 | Pep Tonic Medical Ab | Farmaceutisk komposition innehållande oxytocin eller fragment eller varianter därav och åtminstone en icke-jonisk cellulosaeter |
US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
AR086400A1 (es) | 2011-05-13 | 2013-12-11 | Trimel Pharmaceuticals Corp | Formulaciones en gel intranasal de testosterona en dosis de menor potencia y uso de las mismas para el tratamiento de la anorgasmia o el trastorno de deseo sexual hipoactivo |
US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
JP5717658B2 (ja) * | 2012-01-13 | 2015-05-13 | シスメックス株式会社 | 副腎皮質刺激ホルモンの検出方法および吸着剤 |
US9789071B2 (en) | 2012-06-27 | 2017-10-17 | G2B Pharma, Inc. | Intranasal formulation of epinephrine for the treatment of anaphylaxis |
ES2624294T3 (es) | 2012-07-12 | 2017-07-13 | Mannkind Corporation | Sistemas de suministro de fármacos en polvo seco |
US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
HUE050050T2 (hu) | 2013-03-04 | 2020-11-30 | Besins Healthcare Lu Sarl | Hordozórészecskékhez kötõdõ hatóanyag nanorészecskéket tartalmazó száraz gyógyászati kompozíciók |
KR102499439B1 (ko) | 2013-03-15 | 2023-02-13 | 맨카인드 코포레이션 | 미세결정성 디케토피페라진 조성물 및 방법 |
US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
KR102465025B1 (ko) | 2013-07-18 | 2022-11-09 | 맨카인드 코포레이션 | 열-안정성 건조 분말 약제학적 조성물 및 방법 |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
EP3041461A4 (en) * | 2013-09-03 | 2017-05-03 | G2B Pharma Inc. | Intranasal formulation for the treatment of cardiopulmonary resuscitation (cpr), cardiac life support (cls), anaphylaxis and/or anaphylactoid reactions |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
PT3242676T (pt) | 2015-01-07 | 2023-12-06 | TONIX Pharmaceuticals Holding Corp | Formulações de ocitocina que contém magnésio e métodos de uso |
US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
KR20200092985A (ko) * | 2017-11-27 | 2020-08-04 | 아스카 세이야쿠 가부시키가이샤 | 분말 경비 투여 제제 |
CN108158978A (zh) * | 2018-03-26 | 2018-06-15 | 厦门传福堂药业有限公司 | 一种高分子水性凝胶及其制备方法和用途 |
CN113784703A (zh) * | 2019-05-16 | 2021-12-10 | 株式会社新日本科学 | 经鼻施予用粉末制剂及其制造方法 |
WO2022132018A1 (en) * | 2020-12-16 | 2022-06-23 | Liw Innovation Ab | A new powder composition |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6034925B2 (ja) * | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
JPS607965B2 (ja) * | 1980-08-07 | 1985-02-28 | 帝人株式会社 | 鼻腔粘膜投与用粉剤の製造法 |
JPS59163313A (ja) | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
EP0187433B1 (en) * | 1983-08-01 | 1990-12-27 | Teijin Limited | Powdery pharmaceutical composition suitable for application to mucosa of oral or nasal cavity |
JPS6032714A (ja) * | 1983-08-01 | 1985-02-19 | Teijin Ltd | 鼻腔粘膜に適用するための安定化された粉末状薬学的組成物 |
JPS6034925A (ja) | 1983-08-04 | 1985-02-22 | Mitsubishi Chem Ind Ltd | 2−ヒドロキシイソフタルアルデヒド類の製造法 |
JPS60224616A (ja) * | 1984-04-24 | 1985-11-09 | Teijin Ltd | 経鼻投与用組成物 |
JPS6242888A (ja) | 1985-08-21 | 1987-02-24 | カシオ計算機株式会社 | 太陽電池を備えたicカ−ド |
GB2193891B (en) | 1986-08-18 | 1990-07-25 | Sandoz Ltd | Nasal pharmaceutical composition containing a somatostatin anologue. |
JP3068924B2 (ja) | 1990-11-29 | 2000-07-24 | 旭硝子株式会社 | 熱線遮断膜 |
ATE158172T1 (de) * | 1992-05-26 | 1997-10-15 | Procter & Gamble | Pulverförmige pharmazeutische zusammensetzung |
DE69330672T2 (de) * | 1992-06-12 | 2002-06-27 | Teijin Ltd., Osaka | Pharmazeutische zubereitung zur anwendung in den atemwegen |
ES2171459T3 (es) * | 1993-07-30 | 2002-09-16 | Teijin Ltd | Polvo para administracion nasal de farmaco peptidico o proteinaceo. |
JPH07242550A (ja) | 1994-03-02 | 1995-09-19 | Teijin Ltd | 二次性副甲状腺機能亢進症治療剤 |
DK0943326T4 (da) * | 1996-02-27 | 2007-01-22 | Teijin Ltd | Pulveragtigt præparat til nasal administration |
-
1997
- 1997-02-26 DK DK97905398T patent/DK0943326T4/da active
- 1997-02-26 CN CNB97193861XA patent/CN1155368C/zh not_active Expired - Fee Related
- 1997-02-26 JP JP53078797A patent/JP3634380B2/ja not_active Expired - Fee Related
- 1997-02-26 KR KR1019980706662A patent/KR100568436B1/ko not_active IP Right Cessation
- 1997-02-26 CA CA002247191A patent/CA2247191C/en not_active Expired - Fee Related
- 1997-02-26 EP EP97905398A patent/EP0943326B2/en not_active Expired - Lifetime
- 1997-02-26 AU AU22302/97A patent/AU722319B2/en not_active Ceased
- 1997-02-26 ES ES97905398T patent/ES2205177T5/es not_active Expired - Lifetime
- 1997-02-26 DE DE69724272T patent/DE69724272T3/de not_active Expired - Lifetime
- 1997-02-26 PT PT97905398T patent/PT943326E/pt unknown
- 1997-02-26 WO PCT/JP1997/000541 patent/WO1997031626A1/ja active IP Right Grant
- 1997-02-26 AT AT97905398T patent/ATE247456T1/de active
- 1997-02-26 US US09/125,814 patent/US6881423B2/en not_active Expired - Fee Related
-
2004
- 2004-06-04 US US10/860,058 patent/US7731990B2/en not_active Expired - Fee Related
-
2009
- 2009-11-02 US US12/610,901 patent/US8206748B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20020012688A1 (en) | 2002-01-31 |
JP3634380B2 (ja) | 2005-03-30 |
EP0943326A4 (en) | 2000-12-20 |
WO1997031626A1 (fr) | 1997-09-04 |
AU722319B2 (en) | 2000-07-27 |
DE69724272T2 (de) | 2004-06-09 |
US7731990B2 (en) | 2010-06-08 |
PT943326E (pt) | 2003-12-31 |
US6881423B2 (en) | 2005-04-19 |
AU2230297A (en) | 1997-09-16 |
KR100568436B1 (ko) | 2007-04-25 |
DE69724272D1 (de) | 2003-09-25 |
ES2205177T5 (es) | 2007-08-01 |
DE69724272T3 (de) | 2007-05-10 |
ES2205177T3 (es) | 2004-05-01 |
US20040219108A1 (en) | 2004-11-04 |
CN1155368C (zh) | 2004-06-30 |
CN1216464A (zh) | 1999-05-12 |
ATE247456T1 (de) | 2003-09-15 |
US8206748B2 (en) | 2012-06-26 |
EP0943326B2 (en) | 2006-12-20 |
EP0943326B1 (en) | 2003-08-20 |
KR19990087261A (ko) | 1999-12-15 |
EP0943326A1 (en) | 1999-09-22 |
CA2247191A1 (en) | 1997-09-04 |
DK0943326T3 (da) | 2003-12-08 |
CA2247191C (en) | 2005-01-04 |
US20100047206A1 (en) | 2010-02-25 |
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