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DE69333285D1 - 2-heterozyklisch-5-hydroxy-1,3-pyrimidinen verwendbar als entzündungswidrigesmittel - Google Patents

2-heterozyklisch-5-hydroxy-1,3-pyrimidinen verwendbar als entzündungswidrigesmittel

Info

Publication number
DE69333285D1
DE69333285D1 DE69333285T DE69333285T DE69333285D1 DE 69333285 D1 DE69333285 D1 DE 69333285D1 DE 69333285 T DE69333285 T DE 69333285T DE 69333285 T DE69333285 T DE 69333285T DE 69333285 D1 DE69333285 D1 DE 69333285D1
Authority
DE
Germany
Prior art keywords
heterocyclic
hydroxy
pyrimidine used
inflammable agent
inflammable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69333285T
Other languages
English (en)
Other versions
DE69333285T2 (de
Inventor
Thomas Connor
Rose Kostlan
Charles Unangst
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of DE69333285D1 publication Critical patent/DE69333285D1/de
Application granted granted Critical
Publication of DE69333285T2 publication Critical patent/DE69333285T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69333285T 1992-08-03 1993-07-27 2-heterozyklisch-5-hydroxy-1,3-pyrimidinen verwendbar als entzündungswidrigesmittel Expired - Fee Related DE69333285T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US924212 1992-08-03
US07/924,212 US5240929A (en) 1992-08-03 1992-08-03 2-heterocyclic-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
PCT/US1993/007034 WO1994003448A1 (en) 1992-08-03 1993-07-27 2-heterocyclic-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents

Publications (2)

Publication Number Publication Date
DE69333285D1 true DE69333285D1 (de) 2003-12-11
DE69333285T2 DE69333285T2 (de) 2004-08-26

Family

ID=25449891

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333285T Expired - Fee Related DE69333285T2 (de) 1992-08-03 1993-07-27 2-heterozyklisch-5-hydroxy-1,3-pyrimidinen verwendbar als entzündungswidrigesmittel

Country Status (12)

Country Link
US (2) US5240929A (de)
EP (1) EP0652874B1 (de)
JP (1) JP3223190B2 (de)
KR (1) KR100275428B1 (de)
AT (1) ATE253571T1 (de)
AU (1) AU672619B2 (de)
CA (1) CA2139731C (de)
DE (1) DE69333285T2 (de)
DK (1) DK0652874T3 (de)
ES (1) ES2206460T3 (de)
PT (1) PT652874E (de)
WO (1) WO1994003448A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0569493A4 (en) * 1991-01-31 1993-11-24 Warner-Lambert Company Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines
ATE366569T1 (de) 2000-07-20 2007-08-15 Lauras As Verwendung von cox-2 inhibitoren als immunostimulantien zur behandlung von hiv oder aids
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
NZ530772A (en) * 2001-08-13 2006-03-31 Janssen Pharmaceutica Nv 2,4,5-trisubstituted thiazolyl derivatives and their antiinflammatory activity
DE10329955A1 (de) * 2003-07-03 2005-02-03 Merck Patent Gmbh Verwendung eines hydroalkoholischen Extrakts aus Bauhinia zur Herstellung einer Zubereitung
EP3827747A1 (de) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharmainformatiksystem
DK1919290T3 (da) * 2005-07-12 2014-04-22 Ampio Pharmaceuticals Inc Fremgangsmåder og produkter til behandling af sygdomme
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
EP2398500B1 (de) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Arzneiabgabesystem auf glutathion-basis
MY198422A (en) 2009-04-29 2023-08-29 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US9675587B2 (en) 2013-03-14 2017-06-13 Allergan Holdings Unlimited Company Opioid receptor modulator dosage formulations
WO2023003497A1 (ru) * 2021-07-23 2023-01-26 Общество С Ограниченной Ответственностью "Валента-Интеллект" Соединения с лизосомотропной и противовирусной активностью

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636516A (en) * 1981-02-19 1987-01-13 Yamanouchi Pharmaceutical Co., Ltd. 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds

Also Published As

Publication number Publication date
JPH08500101A (ja) 1996-01-09
CA2139731C (en) 2004-01-13
US5240929A (en) 1993-08-31
EP0652874B1 (de) 2003-11-05
AU4787093A (en) 1994-03-03
PT652874E (pt) 2004-03-31
ATE253571T1 (de) 2003-11-15
KR950702554A (ko) 1995-07-29
US5312821A (en) 1994-05-17
DE69333285T2 (de) 2004-08-26
EP0652874A1 (de) 1995-05-17
KR100275428B1 (ko) 2000-12-15
JP3223190B2 (ja) 2001-10-29
DK0652874T3 (da) 2004-03-22
ES2206460T3 (es) 2004-05-16
CA2139731A1 (en) 1994-02-17
AU672619B2 (en) 1996-10-10
WO1994003448A1 (en) 1994-02-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee