PT652874E - 2-heterociclico-5-hidroxi-1,3-pirimidinas uteis como agentes anti-inflamatorios - Google Patents
2-heterociclico-5-hidroxi-1,3-pirimidinas uteis como agentes anti-inflamatoriosInfo
- Publication number
- PT652874E PT652874E PT93918407T PT93918407T PT652874E PT 652874 E PT652874 E PT 652874E PT 93918407 T PT93918407 T PT 93918407T PT 93918407 T PT93918407 T PT 93918407T PT 652874 E PT652874 E PT 652874E
- Authority
- PT
- Portugal
- Prior art keywords
- heterocyclic
- pyrimidines
- hydroxy
- inflammatory agents
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/924,212 US5240929A (en) | 1992-08-03 | 1992-08-03 | 2-heterocyclic-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT652874E true PT652874E (pt) | 2004-03-31 |
Family
ID=25449891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT93918407T PT652874E (pt) | 1992-08-03 | 1993-07-27 | 2-heterociclico-5-hidroxi-1,3-pirimidinas uteis como agentes anti-inflamatorios |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5240929A (pt) |
| EP (1) | EP0652874B1 (pt) |
| JP (1) | JP3223190B2 (pt) |
| KR (1) | KR100275428B1 (pt) |
| AT (1) | ATE253571T1 (pt) |
| AU (1) | AU672619B2 (pt) |
| CA (1) | CA2139731C (pt) |
| DE (1) | DE69333285T2 (pt) |
| DK (1) | DK0652874T3 (pt) |
| ES (1) | ES2206460T3 (pt) |
| PT (1) | PT652874E (pt) |
| WO (1) | WO1994003448A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0569493A4 (en) * | 1991-01-31 | 1993-11-24 | Warner-Lambert Company | Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines |
| ATE366569T1 (de) | 2000-07-20 | 2007-08-15 | Lauras As | Verwendung von cox-2 inhibitoren als immunostimulantien zur behandlung von hiv oder aids |
| JP4202250B2 (ja) | 2001-07-25 | 2008-12-24 | バイオマリン ファーマシューティカル インコーポレイテッド | 血液脳関門輸送を調節するための組成物および方法 |
| NZ530772A (en) * | 2001-08-13 | 2006-03-31 | Janssen Pharmaceutica Nv | 2,4,5-trisubstituted thiazolyl derivatives and their antiinflammatory activity |
| DE10329955A1 (de) * | 2003-07-03 | 2005-02-03 | Merck Patent Gmbh | Verwendung eines hydroalkoholischen Extrakts aus Bauhinia zur Herstellung einer Zubereitung |
| EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
| DK1919290T3 (da) * | 2005-07-12 | 2014-04-22 | Ampio Pharmaceuticals Inc | Fremgangsmåder og produkter til behandling af sygdomme |
| CA2663377A1 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| EP2398500B1 (en) | 2009-02-20 | 2019-03-13 | 2-BBB Medicines B.V. | Glutathione-based drug delivery system |
| MY198422A (en) | 2009-04-29 | 2023-08-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| IL255113B (en) | 2009-05-06 | 2022-09-01 | Laboratory Skin Care Inc | Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| US9675587B2 (en) | 2013-03-14 | 2017-06-13 | Allergan Holdings Unlimited Company | Opioid receptor modulator dosage formulations |
| WO2023003497A1 (ru) * | 2021-07-23 | 2023-01-26 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Соединения с лизосомотропной и противовирусной активностью |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4636516A (en) * | 1981-02-19 | 1987-01-13 | Yamanouchi Pharmaceutical Co., Ltd. | 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds |
-
1992
- 1992-08-03 US US07/924,212 patent/US5240929A/en not_active Expired - Lifetime
-
1993
- 1993-04-28 US US08/054,382 patent/US5312821A/en not_active Expired - Fee Related
- 1993-07-27 DE DE69333285T patent/DE69333285T2/de not_active Expired - Fee Related
- 1993-07-27 ES ES93918407T patent/ES2206460T3/es not_active Expired - Lifetime
- 1993-07-27 EP EP93918407A patent/EP0652874B1/en not_active Expired - Lifetime
- 1993-07-27 KR KR1019950700375A patent/KR100275428B1/ko not_active IP Right Cessation
- 1993-07-27 DK DK93918407T patent/DK0652874T3/da active
- 1993-07-27 WO PCT/US1993/007034 patent/WO1994003448A1/en active IP Right Grant
- 1993-07-27 JP JP50538494A patent/JP3223190B2/ja not_active Expired - Fee Related
- 1993-07-27 AT AT93918407T patent/ATE253571T1/de not_active IP Right Cessation
- 1993-07-27 AU AU47870/93A patent/AU672619B2/en not_active Ceased
- 1993-07-27 PT PT93918407T patent/PT652874E/pt unknown
- 1993-07-27 CA CA002139731A patent/CA2139731C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69333285D1 (de) | 2003-12-11 |
| JPH08500101A (ja) | 1996-01-09 |
| CA2139731C (en) | 2004-01-13 |
| US5240929A (en) | 1993-08-31 |
| EP0652874B1 (en) | 2003-11-05 |
| AU4787093A (en) | 1994-03-03 |
| ATE253571T1 (de) | 2003-11-15 |
| KR950702554A (ko) | 1995-07-29 |
| US5312821A (en) | 1994-05-17 |
| DE69333285T2 (de) | 2004-08-26 |
| EP0652874A1 (en) | 1995-05-17 |
| KR100275428B1 (ko) | 2000-12-15 |
| JP3223190B2 (ja) | 2001-10-29 |
| DK0652874T3 (da) | 2004-03-22 |
| ES2206460T3 (es) | 2004-05-16 |
| CA2139731A1 (en) | 1994-02-17 |
| AU672619B2 (en) | 1996-10-10 |
| WO1994003448A1 (en) | 1994-02-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9102209A (es) | Derivados de acido hidroxamico y n-hidroxiurea novedosos y su uso. | |
| ES2075845T3 (es) | 3,5-di-terc-butil-4-hidroxifenil-1,3,4-tiadiazoles, oxadiazoles y 3,5-di-terc-butil-4-hidroxifenil-1,2,4-tiadiazoles, oxadiazoles y triazoles como agentes antiinflamatorios. | |
| PT652874E (pt) | 2-heterociclico-5-hidroxi-1,3-pirimidinas uteis como agentes anti-inflamatorios | |
| FI956119A0 (fi) | Fenyyliheterosyklejä syklo-oksigenaasi-2-inhibiittoreina | |
| EA200200708A1 (ru) | Производные бензазола и их применение в качестве модуляторов jnk | |
| PT752987E (pt) | Derivados de pirimidinilo como inibidores da interleucina | |
| ATE294800T1 (de) | N-(5-(((5-alkyl-2-oxazolyl)methyl)thio)-2- thiazolyl)-carboxamide als inhibitoren cyclinabhängiger kinasen | |
| HUP0402352A2 (hu) | Foszfodiészteráz (PDE) 7 inhibitorként alkalmazható pirimidinszármazékok és ezeket tartalmazó gyógyszerkészítmények | |
| NO960393L (no) | Heterosykliske fenylforbindelser som COX-2-inhibitorer | |
| BR9710737A (pt) | Pentafluorobenzenosulfonamidas e análogos. | |
| BR0108816A (pt) | Derivados de quinolina como antagonistas alfa-2 | |
| AR030563A1 (es) | N-[5-[[[5-alquil-2-oxazolil]metil]tio]-2-tiazolil]carboxamidas inhibidoras de cinasas dependientes de la ciclina y composiciones farmaceuticas que las contienen | |
| SE9703414D0 (sv) | New compounds | |
| MX9205123A (es) | Derivados de 5-hidroxi-2-pirimidinilmetileno utiles como agentes anti-inflamatorios. | |
| ATE266027T1 (de) | Optisch aktives pyridyl-4h-1,2,4-oxadiazinderivat und seine verwendung zur behandlung von gefässkrankheiten | |
| ATE223376T1 (de) | Bisarylcyclobutenderivate als cyclooxygenasehemmer | |
| ATE16150T1 (de) | Xanthinoxydasehemmer und verwendung von benztriazinderivaten. | |
| ES2059204T3 (es) | Derivados del acido hidroxamico inhibidores de lipoxigenasa. | |
| DE3778642D1 (de) | Therapeutikum zur behandlung von magengeschwueren. | |
| DE69811734D1 (de) | Carboxylsäure substituierte heterocyclische verbindungen als metalloproteinase inhibitoren | |
| SE9902596D0 (sv) | Pharmaceutically active compounds |