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DE60216630D1 - Verwendung von öestrogen in kombination mit progestogen für die hormonsubstitutions-therapie - Google Patents

Verwendung von öestrogen in kombination mit progestogen für die hormonsubstitutions-therapie

Info

Publication number
DE60216630D1
DE60216630D1 DE60216630T DE60216630T DE60216630D1 DE 60216630 D1 DE60216630 D1 DE 60216630D1 DE 60216630 T DE60216630 T DE 60216630T DE 60216630 T DE60216630 T DE 60216630T DE 60216630 D1 DE60216630 D1 DE 60216630D1
Authority
DE
Germany
Prior art keywords
component
aforementioned
formula
hormone
progestogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60216630T
Other languages
English (en)
Other versions
DE60216630T2 (de
Inventor
Bennink Jan Coelingh
Johannes Bunschoten
Franz Holinka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pantarhei Bioscience BV
Original Assignee
Pantarhei Bioscience BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantarhei Bioscience BV filed Critical Pantarhei Bioscience BV
Publication of DE60216630D1 publication Critical patent/DE60216630D1/de
Application granted granted Critical
Publication of DE60216630T2 publication Critical patent/DE60216630T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60216630T 2001-11-15 2002-05-23 Verwendung von östrogen in kombination mit progestogen für die hormonsubstitutiionstherapie Expired - Lifetime DE60216630T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP01204377 2001-11-15
EP01204377 2001-11-15
EP02075695 2002-02-21
EP02075695 2002-02-21
PCT/NL2002/000332 WO2003041718A1 (en) 2001-11-15 2002-05-23 Use of estrogenic compounds in combination with progestogenic compounds in hormone-replacement therapy

Publications (2)

Publication Number Publication Date
DE60216630D1 true DE60216630D1 (de) 2007-01-18
DE60216630T2 DE60216630T2 (de) 2007-09-20

Family

ID=26077031

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60216630T Expired - Lifetime DE60216630T2 (de) 2001-11-15 2002-05-23 Verwendung von östrogen in kombination mit progestogen für die hormonsubstitutiionstherapie

Country Status (10)

Country Link
US (1) US8026228B2 (de)
EP (1) EP1446128B1 (de)
AT (1) ATE347365T1 (de)
CA (1) CA2467222C (de)
CY (1) CY1105957T1 (de)
DE (1) DE60216630T2 (de)
DK (1) DK1446128T3 (de)
ES (1) ES2278925T3 (de)
PT (1) PT1446128E (de)
WO (1) WO2003041718A1 (de)

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EA023991B1 (ru) 2011-06-01 2016-08-31 Эстетра С.П.Р.Л. Способ получения интермедиатов эстетрола
EP2383279A1 (de) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Herstellungsverfahren für Esterol
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
JP6285866B2 (ja) 2011-11-23 2018-02-28 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然複合ホルモン補充製剤および療法
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US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2013034780A2 (en) 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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CA2947767A1 (en) 2014-05-22 2015-11-26 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
HRP20211968T1 (hr) * 2015-06-18 2022-03-18 Estetra Srl Orodisperzibilna jedinica za doziranje koja sadrži komponentu estetrola
NO3106148T3 (de) * 2015-06-18 2018-08-11
RS61777B1 (sr) 2015-06-18 2021-06-30 Estetra Sprl Oralno-disperzibilna tableta koja sadrži estetrol
ES2877186T3 (es) 2015-06-18 2021-11-16 Estetra Sprl Comprimido orodispersable que contiene estetrol
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
JP2019513709A (ja) 2016-04-01 2019-05-30 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． ステロイドホルモン薬学的組成物
KR102712911B1 (ko) 2016-08-05 2024-10-04 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
US10285998B1 (en) 2018-04-04 2019-05-14 The Menopause Method, Inc. Composition and method to aid in hormone replacement therapy
JOP20200260A1 (ar) * 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
MX2024006490A (es) * 2021-11-29 2024-06-05 Estetra Srl Composiciones para prevenir o tratar el envejecimiento de la piel.

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Also Published As

Publication number Publication date
EP1446128B1 (de) 2006-12-06
CY1105957T1 (el) 2011-04-06
US8026228B2 (en) 2011-09-27
ES2278925T3 (es) 2007-08-16
DK1446128T3 (da) 2007-04-02
CA2467222A1 (en) 2003-05-22
WO2003041718A1 (en) 2003-05-22
EP1446128A1 (de) 2004-08-18
CA2467222C (en) 2010-06-08
DE60216630T2 (de) 2007-09-20
PT1446128E (pt) 2007-03-30
US20050070488A1 (en) 2005-03-31
ATE347365T1 (de) 2006-12-15

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