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DE602006018969D1 - Herstellung und reinigung von il-29 - Google Patents

Herstellung und reinigung von il-29

Info

Publication number
DE602006018969D1
DE602006018969D1 DE602006018969T DE602006018969T DE602006018969D1 DE 602006018969 D1 DE602006018969 D1 DE 602006018969D1 DE 602006018969 T DE602006018969 T DE 602006018969T DE 602006018969 T DE602006018969 T DE 602006018969T DE 602006018969 D1 DE602006018969 D1 DE 602006018969D1
Authority
DE
Germany
Prior art keywords
methods
cleaning
preparation
coli
vectors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006018969T
Other languages
English (en)
Inventor
Bruce L Zamost
Geoffrey F Lee
Robert M Dedinsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Zymogenetics LLC
Original Assignee
Bristol Myers Squibb Co
Zymogenetics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co, Zymogenetics LLC filed Critical Bristol Myers Squibb Co
Publication of DE602006018969D1 publication Critical patent/DE602006018969D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602006018969T 2005-10-04 2006-10-04 Herstellung und reinigung von il-29 Active DE602006018969D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72354405P 2005-10-04 2005-10-04
PCT/US2006/039139 WO2007041713A1 (en) 2005-10-04 2006-10-04 Production and purification of il-29

Publications (1)

Publication Number Publication Date
DE602006018969D1 true DE602006018969D1 (de) 2011-01-27

Family

ID=37603659

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006018969T Active DE602006018969D1 (de) 2005-10-04 2006-10-04 Herstellung und reinigung von il-29

Country Status (15)

Country Link
US (6) US20080096252A1 (de)
EP (1) EP1931704B1 (de)
JP (3) JP5364375B2 (de)
AT (1) ATE491722T1 (de)
AU (1) AU2006299339B2 (de)
CA (1) CA2625208A1 (de)
CY (1) CY1112323T1 (de)
DE (1) DE602006018969D1 (de)
DK (1) DK1931704T3 (de)
ES (1) ES2357152T3 (de)
IL (2) IL189994A (de)
PL (1) PL1931704T3 (de)
PT (1) PT1931704E (de)
SI (1) SI1931704T1 (de)
WO (1) WO2007041713A1 (de)

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AR067537A1 (es) 2007-07-17 2009-10-14 Hoffmann La Roche Purificacion de polipeptidos pegilados
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CA2711375C (en) 2008-01-18 2019-04-16 F. Hoffmann-La Roche Ag Purification of not-glycosylated polypeptides
CN103536906A (zh) * 2008-06-05 2014-01-29 津莫吉尼蒂克斯公司 利用聚乙二醇化的iii 型干扰素治疗丙型肝炎
WO2010059232A1 (en) 2008-11-20 2010-05-27 Biogen Idec Ma Inc. Arginine inactivation of viruses
CN102256625B (zh) 2008-12-17 2013-11-20 默沙东公司 单和双peg il10的生产和用途
EP2417244A4 (de) * 2009-04-10 2015-10-14 Reg Life Sciences Llc Herstellung von gewerblichem biodiesel aus genmanipulierten mikroorganismen
EP2535057A2 (de) 2010-02-09 2012-12-19 Proyecto de Biomedicina Cima, S.L. Zusammensetzung zur behandlung von infektions- und tumorerkrankungen
JP5768341B2 (ja) * 2010-08-04 2015-08-26 東ソー株式会社 Ｆｃ結合性タンパク質の製造方法
CN102584979B (zh) * 2011-01-18 2015-10-14 北京凯因科技股份有限公司 PEG化干扰素λ
US10201584B1 (en) 2011-05-17 2019-02-12 Abbvie Inc. Compositions and methods for treating HCV
CA2846092A1 (en) * 2011-08-25 2013-02-28 Nanogen Pharmaceutical Biotechnology Peg-interferon lambda 1 conjugates
US8454947B1 (en) 2012-03-01 2013-06-04 Nanogen Pharmaceutical Biotechnology PEG-interferon lambda 1 conjugates
RU2549710C2 (ru) * 2012-06-29 2015-04-27 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа
JP6086378B2 (ja) * 2012-11-30 2017-03-01 国立大学法人お茶の水女子大学 組み換えヒト膵臓リパーゼの調製方法
CN104045704B (zh) * 2013-03-11 2016-08-10 中国医学科学院基础医学研究所 PEG化重组人IFN-λ1、其制备方法和用途
WO2014172392A1 (en) 2013-04-18 2014-10-23 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
ES2688206T3 (es) 2013-06-17 2018-10-31 Armo Biosciences, Inc. Procedimiento de evaluación de la identidad y la estabilidad de proteínas
IN2013MU02416A (de) * 2013-07-19 2015-06-19 Biogenomics Ltd
CA2920679A1 (en) 2013-08-30 2015-03-05 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
RU2016122957A (ru) 2013-11-11 2017-12-19 Армо Байосайенсиз, Инк. Способы применения интерлейкина-10 для лечения заболеваний и расстройств
US10246501B2 (en) 2014-01-08 2019-04-02 Prosit Sole Biotechnology (Beijing) Co, Ltd Fusion polypeptides and methods of use
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2015187295A2 (en) 2014-06-02 2015-12-10 Armo Biosciences, Inc. Methods of lowering serum cholesterol
MX2017004838A (es) 2014-10-14 2017-10-16 Armo Biosciences Inc Composiciones de interleucina-15 y usos de estas.
WO2016064817A1 (en) 2014-10-22 2016-04-28 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US20170362291A1 (en) * 2014-12-23 2017-12-21 Armo Biosciences, Inc. Methods of Improving Yield in Recombinant Protein Production
US10618970B2 (en) 2015-02-03 2020-04-14 Armo Biosciences, Inc. Method of treating cancer with IL-10 and antibodies that induce ADCC
EP3285768B1 (de) 2015-04-21 2020-12-30 Eiger Biopharmaceuticals, Inc. Pharmazeutische zusammensetzungen mit lonafarnib und ritonavir
CA2986755A1 (en) 2015-05-28 2016-12-01 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
CN108025040A (zh) 2015-08-25 2018-05-11 阿尔莫生物科技股份有限公司 使用白介素-10治疗疾病和病症的方法
WO2017143253A1 (en) 2016-02-19 2017-08-24 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection with interferon lambda
MX2019004717A (es) * 2016-11-07 2019-08-05 Seattle Genetics Inc Distribucion de casquetes de cisteina modificados.
CN113474361B (zh) 2019-02-24 2023-11-14 昂科斯密斯生物技术私人有限公司 由细菌连续生产重组glp-1肽的方法

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US4795077A (en) * 1988-05-23 1989-01-03 Motorola Inc. Bonding method and apparatus
EP0626448A3 (de) * 1993-05-26 1998-01-14 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verfahren zur Herstellung und Reinigung von alpha-Interferon
WO2000032772A2 (en) * 1998-11-30 2000-06-08 Eli Lilly And Company Erythropoietic compounds
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RU2292394C2 (ru) * 2000-06-30 2007-01-27 ЗАЙМОДЖЕНЕТИКС, Инк., Интерферон-подобный белок zcyto21
US7038032B2 (en) * 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
AU2003286624B2 (en) * 2002-10-23 2008-11-13 Bristol-Myers Squibb Company Methods for treating viral infection using IL-28 and IL-29
KR101098897B1 (ko) * 2002-12-13 2011-12-26 지모제넥틱스, 인코포레이티드 원핵생물 숙주 내 ｉｌ-21 생산
PT2251353E (pt) * 2003-08-07 2013-05-07 Zymogenetics Inc Preparações homogéneas de il-28 e il-29
EP1750749A2 (de) 2004-04-02 2007-02-14 ZymoGenetics, Inc. Il-28 und il-29-cystein-mutanten zur behandlung von virusinfektion
EP2389944A1 (de) * 2004-07-29 2011-11-30 ZymoGenetics, L.L.C. Nutzung von IL-28 und IL-29 zur Behandlung von Krebs
CN1305902C (zh) * 2004-11-25 2007-03-21 汕头大学医学院 一种人白细胞介素29的生产方法及重组il－29工程菌
CA2592261C (en) * 2004-12-10 2015-11-24 Zymogenetics Inc. Fgf18 production in prokaryotic hosts
CA2616004A1 (en) * 2005-07-20 2007-02-01 Zymogenetics, Inc. Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders
DE602006018969D1 (de) 2005-10-04 2011-01-27 Bristol Myers Squibb Co Herstellung und reinigung von il-29

Also Published As

Publication number Publication date
JP2012235789A (ja) 2012-12-06
PL1931704T3 (pl) 2011-06-30
US20080096252A1 (en) 2008-04-24
US7968315B2 (en) 2011-06-28
DK1931704T3 (da) 2011-03-14
JP2009510173A (ja) 2009-03-12
US8759027B2 (en) 2014-06-24
US20100222552A1 (en) 2010-09-02
US20120015403A1 (en) 2012-01-19
IL189994A (en) 2013-08-29
EP1931704A1 (de) 2008-06-18
US7759092B2 (en) 2010-07-20
WO2007041713A1 (en) 2007-04-12
IL189994A0 (en) 2008-08-07
ES2357152T3 (es) 2011-04-19
US20120271037A1 (en) 2012-10-25
PT1931704E (pt) 2011-03-28
US8211670B2 (en) 2012-07-03
EP1931704B1 (de) 2010-12-15
JP5364375B2 (ja) 2013-12-11
AU2006299339B2 (en) 2012-03-15
US20130143270A1 (en) 2013-06-06
AU2006299339A1 (en) 2007-04-12
ATE491722T1 (de) 2011-01-15
SI1931704T1 (sl) 2011-04-29
IL227691A0 (en) 2013-09-30
CA2625208A1 (en) 2007-04-12
CY1112323T1 (el) 2015-12-09
JP2013099337A (ja) 2013-05-23
US20100003722A1 (en) 2010-01-07

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