DE60142913D1 - Arzneilösungen enthaltend modafinilverbindungen - Google Patents

Arzneilösungen enthaltend modafinilverbindungen

Info

Publication number: DE60142913D1
Authority: DE; Germany
Prior art keywords: modafinil compounds; drug solutions; solutions contain; contain modafinil; compounds
Prior art date: 2000-10-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60142913T

Other languages

English (en)

Inventor

Martin J Jacobs

Bradley T Mcintyre

Piyush R Patel

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cephalon LLC

Original Assignee

Cephalon LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-11

Filing date

2001-10-11

Publication date

2010-10-07

2001-10-11 Application filed by Cephalon LLC filed Critical Cephalon LLC

2010-10-07 Application granted granted Critical

2010-10-07 Publication of DE60142913D1 publication Critical patent/DE60142913D1/de

2021-10-12 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oil, Petroleum & Natural Gas (AREA)
Psychology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE60142913T 2000-10-11 2001-10-11 Arzneilösungen enthaltend modafinilverbindungen Expired - Lifetime DE60142913D1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US23948800P	2000-10-11	2000-10-11
US09/974,473 US6489363B2 (en)	2000-10-11	2001-10-10	Pharmaceutical solutions of modafinil compounds
PCT/US2001/031685 WO2002030413A1 (en)	2000-10-11	2001-10-11	Pharmaceutical solutions of modafinil compounds

Publications (1)

Publication Number	Publication Date
DE60142913D1 true DE60142913D1 (de)	2010-10-07

Family

ID=26932612

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60142913T Expired - Lifetime DE60142913D1 (de)	2000-10-11	2001-10-11	Arzneilösungen enthaltend modafinilverbindungen

Country Status (22)

Country	Link
US (1)	US6489363B2 (de)
EP (1)	EP1324755B1 (de)
JP (1)	JP2004510816A (de)
KR (1)	KR100846914B1 (de)
CN (1)	CN100518726C (de)
AT (1)	ATE478662T1 (de)
AU (2)	AU9678501A (de)
BG (1)	BG66221B1 (de)
BR (1)	BR0114813A (de)
CA (1)	CA2425218C (de)
CZ (1)	CZ2003966A3 (de)
DE (1)	DE60142913D1 (de)
EA (1)	EA005572B1 (de)
HK (1)	HK1057336A1 (de)
HU (1)	HU229424B1 (de)
IL (2)	IL155263A0 (de)
MX (1)	MXPA03003150A (de)
NO (1)	NO333096B1 (de)
NZ (1)	NZ525166A (de)
PL (1)	PL214879B1 (de)
SK (1)	SK287436B6 (de)
WO (1)	WO2002030413A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2425338C (en) *	2000-10-11	2010-04-20	Cephalon, Inc.	Compositions comprising modafinil compounds
US6919378B2 (en) *	2000-10-11	2005-07-19	Cephalon, Inc.	Pharmaceutical solutions of modafinil compounds
US6992219B2 (en) *	2002-08-09	2006-01-31	Cephalon France	Modafinil polymorphic forms
US20040116532A1 (en)	2002-09-13	2004-06-17	Craig Heacock	Pharmaceutical formulations of modafinil
FR2849029B1 (fr) *	2002-12-20	2005-03-18	Lafon Labor	Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
AU2004222307B2 (en) *	2003-03-17	2008-04-17	Neurohealing Pharmaceuticals, Inc.	High potency dopaminergic treatment of neurological impairment associated with brain injury
US20040253308A1 (en) *	2003-04-29	2004-12-16	Barr Laboratories, Inc.	Surface-treated modafinil particles
US8153159B2 (en) *	2003-09-18	2012-04-10	Cephalon, Inc.	Modafinil modified release pharmaceutical compositions
US7368591B2 (en)	2003-09-19	2008-05-06	Cephalon France	Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US20060024370A1 (en) *	2004-07-29	2006-02-02	Cephalon France	Modafinil oral lyophilizate
BRPI0500520A (pt) *	2005-02-16	2006-09-26	Henry Jun Suzuki	uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticas
AU2006272874B2 (en) *	2005-07-21	2010-03-11	Neurohealing Pharmaceuticals, Inc.	Rapid onset and short term modafinil compositions and methods of use thereof
WO2008021341A2 (en)	2006-08-14	2008-02-21	Neurohealing Pharmaceuticals, Inc.	Modafinil-based treatment for premature ejaculation
US8173169B2 (en) *	2007-07-11	2012-05-08	Hikma Pharmaceuticals	Formulation and process for the preparation of modafinil
CA2629979A1 (en) *	2008-04-25	2009-10-25	Pharmascience Inc.	Novel resveratrol compositions
FR2987266B1 (fr)	2012-02-28	2014-12-19	Debregeas Et Associes Pharma	Procede d'obtention d'une composition pharmaceutique a base de modafinil, composition pharmaceutique ainsi obtenue et son application
FR2987265B1 (fr)	2012-02-28	2014-02-28	Debregeas Et Associes Pharma	Composition pharmaceutique sous forme de sirop a base de modafinil, son procede de fabrication et son application
CA2888883A1 (en) *	2012-10-18	2014-04-24	Abbvie Inc.	Formulations of pyrimidinedione derivative compounds
US9616068B2 (en)	2014-10-27	2017-04-11	Pohela LLC	Animal training using cognitive enhancement

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1584462A (en)	1977-03-31	1981-02-11	Lafon Labor	N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr)	1986-01-31	1988-07-22	Lafon Labor	Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
FR2663225B1 (fr)	1990-06-14	1994-11-04	Lafon Labor	Nouvelle utilisation du modafinil.
US5618845A (en) *	1994-10-06	1997-04-08	Cephalon, Inc.	Acetamide derivative having defined particle size
FR2771004B1 (fr)	1997-11-19	2000-02-18	Inst Curie	Utilisation de derives de benzhydryl sulfinyle pour la fabrication de medicaments ayant un effet eveillant dans des situations de troubles de la vigilance d'origine medicamenteuse
US6200968B1 (en)	1998-08-06	2001-03-13	Cephalon, Inc.	Particle-forming compositions containing fused pyrrolocarbazoles
US20010034373A1 (en)	2000-02-09	2001-10-25	Matthew Miller	Low dose modafinil for enhancement of cognitive function

2001
- 2001-10-10 US US09/974,473 patent/US6489363B2/en not_active Expired - Lifetime
- 2001-10-11 AU AU9678501A patent/AU9678501A/xx active Pending
- 2001-10-11 AT AT01977685T patent/ATE478662T1/de not_active IP Right Cessation
- 2001-10-11 MX MXPA03003150A patent/MXPA03003150A/es active IP Right Grant
- 2001-10-11 CN CNB018171273A patent/CN100518726C/zh not_active Expired - Fee Related
- 2001-10-11 IL IL15526301A patent/IL155263A0/xx active IP Right Review Request
- 2001-10-11 EA EA200300450A patent/EA005572B1/ru not_active IP Right Cessation
- 2001-10-11 HU HU0302478A patent/HU229424B1/hu not_active IP Right Cessation
- 2001-10-11 WO PCT/US2001/031685 patent/WO2002030413A1/en active Application Filing
- 2001-10-11 EP EP01977685A patent/EP1324755B1/de not_active Expired - Lifetime
- 2001-10-11 KR KR1020037005057A patent/KR100846914B1/ko not_active IP Right Cessation
- 2001-10-11 SK SK440-2003A patent/SK287436B6/sk not_active IP Right Cessation
- 2001-10-11 CZ CZ2003966A patent/CZ2003966A3/cs unknown
- 2001-10-11 DE DE60142913T patent/DE60142913D1/de not_active Expired - Lifetime
- 2001-10-11 NZ NZ525166A patent/NZ525166A/en not_active IP Right Cessation
- 2001-10-11 PL PL361134A patent/PL214879B1/pl unknown
- 2001-10-11 AU AU2001296785A patent/AU2001296785B2/en not_active Ceased
- 2001-10-11 JP JP2002533856A patent/JP2004510816A/ja active Pending
- 2001-10-11 CA CA2425218A patent/CA2425218C/en not_active Expired - Fee Related
- 2001-10-11 BR BR0114813-3A patent/BR0114813A/pt active Search and Examination
2003
- 2003-04-06 IL IL155263A patent/IL155263A/en not_active IP Right Cessation
- 2003-04-10 NO NO20031648A patent/NO333096B1/no not_active IP Right Cessation
- 2003-04-14 BG BG107720A patent/BG66221B1/bg unknown
2004
- 2004-01-09 HK HK04100157.5A patent/HK1057336A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1324755B1 (de)	2010-08-25
KR20030055279A (ko)	2003-07-02
NZ525166A (en)	2006-10-27
CZ2003966A3 (cs)	2003-09-17
ATE478662T1 (de)	2010-09-15
HU229424B1 (hu)	2013-12-30
NO333096B1 (no)	2013-03-04
AU2001296785B2 (en)	2006-03-16
AU9678501A (en)	2002-04-22
IL155263A (en)	2007-07-24
HK1057336A1 (en)	2004-04-02
NO20031648L (no)	2003-06-04
WO2002030413A1 (en)	2002-04-18
US20020099097A1 (en)	2002-07-25
CN100518726C (zh)	2009-07-29
IL155263A0 (en)	2003-11-23
EP1324755A1 (de)	2003-07-09
SK4402003A3 (en)	2003-09-11
US6489363B2 (en)	2002-12-03
MXPA03003150A (es)	2003-07-14
PL214879B1 (pl)	2013-09-30
CA2425218A1 (en)	2002-04-18
CA2425218C (en)	2010-10-05
KR100846914B1 (ko)	2008-07-17
EA005572B1 (ru)	2005-04-28
HUP0302478A3 (en)	2005-05-30
BG107720A (bg)	2004-01-30
HUP0302478A2 (hu)	2003-11-28
BR0114813A (pt)	2005-01-25
SK287436B6 (sk)	2010-09-07
NO20031648D0 (no)	2003-04-10
PL361134A1 (en)	2004-09-20
BG66221B1 (bg)	2012-06-29
EA200300450A1 (ru)	2003-08-28
JP2004510816A (ja)	2004-04-08
CN1468096A (zh)	2004-01-14

Publication	Publication Date	Title
DE60142913D1 (de)	2010-10-07	Arzneilösungen enthaltend modafinilverbindungen
HK1079446A1 (en)	2006-04-07	Pharmeceutical solid dispersions of modafinil compounds
SE0100901D0 (sv)	2001-03-15	New composition
ATE512163T1 (de)	2011-06-15	Verabreichung von mitteln zur behandlung von entzündungen
UY27175A1 (es)	2002-09-30	Nueva sal succinato de o-desmetil- venlafaxina
NO324227B1 (no)	2007-09-10	Cyclopropyl-kondenserte pyrrolidin-baserte forbindelser, farmasoytiske blandinger og kombinasjoner inneholdende slike samt anvendelse av slike for fremstilling av medikamenter for behandling av sykdommer
DE60313597D1 (de)	2007-06-14	Topische pharmazeutische zusammensetzungen mit proanthocyanidinen, glycyrrhetinic säure und telmesteine zur behandlung von dermatitis
DE60336664D1 (de)	2011-05-19	Nichtnukleosidische reverse-transkriptase-hemmer
AR027355A1 (es)	2003-03-26	Acidos tiazolidincarboxilicos
SE0101932D0 (sv)	2001-05-31	Pharmaceutical combinations
SE9802208D0 (sv)	1998-06-22	Novel compounds
EA200501821A1 (ru)	2006-06-30	Фармацевтическая комбинация, содержащая модафинил и другой лекарственный препарат
WO2003066597A3 (en)	2004-04-01	Guanidino compounds
NO20043792L (no)	2005-01-04	New heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in medicine
SE0003476D0 (sv)	2000-09-28	Compounds
HUP0200152A2 (hu)	2002-05-29	KQT1 csatornák gátlóinak alkalmazása parazita férgek és ektoparaziták által okozott betegségek kezelésére alkalmas gyógyszerkészítmények előállítására
NO20051261L (no)	2005-03-11	Morfin-6-glukuronidsalt
CY1105165T1 (el)	2010-03-03	Φαρμακευτικη συνθεση που πepιλαμβανει συνδυασμο μετφορμινης και 4-οξοβουτανικου οξεος και η χρηση αυτης για τη θepαπεια του διαβητη
DE60137069D1 (de)	2009-01-29	Arzneizusammensetzungen enthaltend modafinilverbindungen
SE0001916D0 (sv)	2000-05-23	Novel formulation
SE0000303D0 (sv)	2000-01-31	Novel compounds
DE60003074D1 (de)	2003-07-03	Fusidinsäure-derivate
SE0300535D0 (sv)	2003-02-28	Treatment of burns
DE50304524D1 (de)	2006-09-14	Arzneimittel enthaltend substituierte 2,5-diaminomethyl-1h-pyrrole
ATE382363T1 (de)	2008-01-15	Pharmazeutische zusammensetzung enthaltend bulbophyllum