DE60113865D1 - Piperazin derivate - Google Patents

Piperazin derivate

Info

Publication number: DE60113865D1
Authority: DE; Germany
Prior art keywords: piperazine derivatives; piperazine; derivatives
Prior art date: 2000-07-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60113865T

Other languages

English (en)

Other versions

DE60113865T2 (de

Inventor

Mark Bentley

Paul Hebeisen

Marc Muller

Hans Richter

Stephan Roever

Patrizio Mattei

Sven Taylor

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Ligand UK Research Ltd

Original Assignee

F Hoffmann La Roche AG

Vernalis Research Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-31

Filing date

2001-07-24

Publication date

2006-02-16

2001-07-24 Application filed by F Hoffmann La Roche AG, Vernalis Research Ltd filed Critical F Hoffmann La Roche AG

2006-02-16 Publication of DE60113865D1 publication Critical patent/DE60113865D1/de

2006-07-20 Application granted granted Critical

2006-07-20 Publication of DE60113865T2 publication Critical patent/DE60113865T2/de

2021-07-25 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Obesity (AREA)
Endocrinology (AREA)
Anesthesiology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Child & Adolescent Psychology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DE60113865T 2000-07-31 2001-07-24 Piperazin derivate Expired - Fee Related DE60113865T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP00116517		2000-07-31
EP00116517		2000-07-31
PCT/EP2001/008520 WO2002010169A1 (en)	2000-07-31	2001-07-24	Piperazine derivatives

Publications (2)

Publication Number	Publication Date
DE60113865D1 true DE60113865D1 (de)	2006-02-16
DE60113865T2 DE60113865T2 (de)	2006-07-20

Family

ID=8169405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60113865T Expired - Fee Related DE60113865T2 (de)	2000-07-31	2001-07-24	Piperazin derivate

Country Status (20)

Country	Link
US (4)	US20020035110A1 (de)
EP (1)	EP1325008B1 (de)
JP (1)	JP4180365B2 (de)
KR (1)	KR100539139B1 (de)
CN (1)	CN1277828C (de)
AR (1)	AR030306A1 (de)
AT (1)	ATE305933T1 (de)
AU (2)	AU2001283955B2 (de)
BR (1)	BR0112918A (de)
CA (1)	CA2417106C (de)
DE (1)	DE60113865T2 (de)
DK (1)	DK1325008T3 (de)
ES (1)	ES2250459T3 (de)
GT (1)	GT200100155A (de)
MX (1)	MXPA03000906A (de)
PA (1)	PA8523601A1 (de)
PE (1)	PE20020366A1 (de)
UY (1)	UY26863A1 (de)
WO (1)	WO2002010169A1 (de)
ZA (1)	ZA200300525B (de)

Families Citing this family (86)

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2001
- 2001-07-24 AT AT01962869T patent/ATE305933T1/de not_active IP Right Cessation
- 2001-07-24 WO PCT/EP2001/008520 patent/WO2002010169A1/en active IP Right Grant
- 2001-07-24 MX MXPA03000906A patent/MXPA03000906A/es active IP Right Grant
- 2001-07-24 JP JP2002515898A patent/JP4180365B2/ja not_active Expired - Fee Related
- 2001-07-24 ES ES01962869T patent/ES2250459T3/es not_active Expired - Lifetime
- 2001-07-24 DE DE60113865T patent/DE60113865T2/de not_active Expired - Fee Related
- 2001-07-24 EP EP01962869A patent/EP1325008B1/de not_active Expired - Lifetime
- 2001-07-24 CN CNB018152260A patent/CN1277828C/zh not_active Expired - Fee Related
- 2001-07-24 CA CA002417106A patent/CA2417106C/en not_active Expired - Fee Related
- 2001-07-24 KR KR10-2003-7001439A patent/KR100539139B1/ko not_active IP Right Cessation
- 2001-07-24 DK DK01962869T patent/DK1325008T3/da active
- 2001-07-24 BR BR0112918-0A patent/BR0112918A/pt not_active IP Right Cessation
- 2001-07-24 AU AU2001283955A patent/AU2001283955B2/en not_active Ceased
- 2001-07-24 AU AU8395501A patent/AU8395501A/xx active Pending
- 2001-07-25 PE PE2001000749A patent/PE20020366A1/es not_active Application Discontinuation
- 2001-07-25 US US09/912,949 patent/US20020035110A1/en not_active Abandoned
- 2001-07-27 AR ARP010103589A patent/AR030306A1/es unknown
- 2001-07-30 GT GT200100155A patent/GT200100155A/es unknown
- 2001-07-30 UY UY26863A patent/UY26863A1/es not_active Application Discontinuation
- 2001-07-30 PA PA20018523601A patent/PA8523601A1/es unknown
2003
- 2003-01-20 ZA ZA200300525A patent/ZA200300525B/en unknown
- 2003-03-25 US US10/396,242 patent/US6933387B2/en not_active Expired - Fee Related
2005
- 2005-06-28 US US11/169,079 patent/US7253281B2/en not_active Expired - Fee Related
2007
- 2007-01-03 US US11/649,132 patent/US20070106076A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN1277828C (zh)	2006-10-04
GT200100155A (es)	2002-05-16
US20070106076A1 (en)	2007-05-10
WO2002010169A1 (en)	2002-02-07
AU8395501A (en)	2002-02-13
UY26863A1 (es)	2002-01-31
CA2417106A1 (en)	2002-02-07
US20030216401A1 (en)	2003-11-20
US20050239789A1 (en)	2005-10-27
BR0112918A (pt)	2003-07-01
JP4180365B2 (ja)	2008-11-12
US6933387B2 (en)	2005-08-23
ATE305933T1 (de)	2005-10-15
PE20020366A1 (es)	2002-05-17
ES2250459T3 (es)	2006-04-16
KR20030020954A (ko)	2003-03-10
DE60113865T2 (de)	2006-07-20
EP1325008B1 (de)	2005-10-05
MXPA03000906A (es)	2005-02-24
CA2417106C (en)	2007-09-18
JP2004505085A (ja)	2004-02-19
US20020035110A1 (en)	2002-03-21
KR100539139B1 (ko)	2005-12-26
CN1452622A (zh)	2003-10-29
AR030306A1 (es)	2003-08-20
AU2001283955B2 (en)	2006-05-18
EP1325008A1 (de)	2003-07-09
US7253281B2 (en)	2007-08-07
DK1325008T3 (da)	2006-02-13
ZA200300525B (en)	2004-04-20
PA8523601A1 (es)	2002-10-24

Publication	Publication Date	Title
DE60113865D1 (de)	2006-02-16	Piperazin derivate
DE60134338D1 (de)	2008-07-17	Piperazin-derivate
EE200200567A (et)	2004-06-15	Uued piperasiini derivaadid
DE60120366D1 (de)	2006-07-20	Arylkondensiete azapolycyclische derivate
DE60009147T2 (de)	2005-04-21	Admantan derivate
CH1175401H1 (de)	2007-02-15	Piperazin Derivate verwendbar als CCR5 Antagonisten
DK1198453T5 (da)	2005-01-31	N-(indolcarbonyl-)piperazinderivater
NO20043079L (no)	2004-09-21	Piperazinderivat
NO20023787D0 (no)	2002-08-09	Piperazin- og piperidinderivater
ATE273980T1 (de)	2004-09-15	6-phenylpyrrolopyrimidindion derivate
ATE298332T1 (de)	2005-07-15	Decahydro-isochinolinderivate
ATE273962T1 (de)	2004-09-15	5-phenyl-pyrimidine derivate
DK1280809T3 (da)	2005-11-07	Antitumorecteinascidinderivater
DE69930543D1 (de)	2006-05-11	Piperazin-derivate
NO20031572L (no)	2003-06-10	Brodannete piperazinderivater
DE60204044D1 (de)	2005-06-09	Piperazin derivate mit sst1 antagonistischer wirkung
DE60025918D1 (de)	2006-04-20	4-phenyl-pyrimidine derivate
ATE365738T1 (de)	2007-07-15	Neue pleuromutilin derivate
NO20023954D0 (no)	2002-08-20	Substituerte piperasinforbindelser
DK1246791T3 (da)	2005-02-14	Aminomethyl-phenyl-cyklohexanonderivater
DE60143905D1 (de)	2011-03-03	Phtalazinon derivate
DE60103859D1 (de)	2004-07-22	2-phenylpyran-4-on derivate
ATE374776T1 (de)	2007-10-15	Pyrrolotriazolopyrimidinonderivate

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