DE60004669D1 - Indolocarbazolalkaloide aus einer marinen actinomycete - Google Patents
Indolocarbazolalkaloide aus einer marinen actinomyceteInfo
- Publication number
- DE60004669D1 DE60004669D1 DE60004669T DE60004669T DE60004669D1 DE 60004669 D1 DE60004669 D1 DE 60004669D1 DE 60004669 T DE60004669 T DE 60004669T DE 60004669 T DE60004669 T DE 60004669T DE 60004669 D1 DE60004669 D1 DE 60004669D1
- Authority
- DE
- Germany
- Prior art keywords
- carbon atoms
- indolocarbazolal
- caloids
- actinomycete
- navy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- DJBWJQBHFUNODD-UHFFFAOYSA-N indolo[3,2-c]carbazole-1-carbaldehyde Chemical compound C1=CC2=C3C=CC=CC3=NC2=C2C1=NC1=C2C(C=O)=CC=C1 DJBWJQBHFUNODD-UHFFFAOYSA-N 0.000 title 1
- 241001446247 uncultured actinomycete Species 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9915069 | 1999-06-28 | ||
GBGB9915069.0A GB9915069D0 (en) | 1999-06-28 | 1999-06-28 | New indolocarbazole alkaloids from a marine actinomycete |
PCT/GB2000/002473 WO2001000627A1 (en) | 1999-06-28 | 2000-06-28 | New indolocarbazole alkaloids from a marine actinomycete |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60004669D1 true DE60004669D1 (de) | 2003-09-25 |
DE60004669T2 DE60004669T2 (de) | 2004-07-08 |
Family
ID=10856186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60004669T Expired - Fee Related DE60004669T2 (de) | 1999-06-28 | 2000-06-28 | Indolocarbazolalkaloide aus einer marinen actinomycete |
Country Status (17)
Country | Link |
---|---|
US (1) | US6852715B1 (de) |
EP (1) | EP1189908B1 (de) |
JP (1) | JP2003503412A (de) |
KR (1) | KR20020037730A (de) |
CN (1) | CN1152881C (de) |
AT (1) | ATE247662T1 (de) |
AU (1) | AU775414B2 (de) |
BR (1) | BR0012457A (de) |
CA (1) | CA2377147C (de) |
DE (1) | DE60004669T2 (de) |
DK (1) | DK1189908T3 (de) |
ES (1) | ES2202142T3 (de) |
GB (1) | GB9915069D0 (de) |
IL (1) | IL147307A0 (de) |
MX (1) | MXPA02000173A (de) |
PT (1) | PT1189908E (de) |
WO (1) | WO2001000627A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7222176B1 (en) | 2000-08-28 | 2007-05-22 | Datacore Software Corporation | Apparatus and method for using storage domains for controlling data in storage area networks |
CN103980266B (zh) * | 2014-04-02 | 2016-01-20 | 浙江大学 | 一种具有抗菌活性的化合物及其制备方法 |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
CN107417743B (zh) * | 2017-06-15 | 2020-07-21 | 杭州科兴生物化工有限公司 | 星孢菌素醛基取代衍生物及其制备方法和应用 |
CN107674105B (zh) * | 2017-09-27 | 2020-05-22 | 杭州科兴生物化工有限公司 | 吲哚咔唑类化合物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5093330A (en) * | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
JPH05247055A (ja) * | 1992-03-03 | 1993-09-24 | Meiji Seika Kaisha Ltd | スタウロスポリン誘導体及びそれを含有する抗腫瘍効果増強剤 |
EP0655066A1 (de) * | 1992-08-12 | 1995-05-31 | PHARMACIA & UPJOHN COMPANY | Proteinkinase-inhibitoren und verwandte verbindungen kombiniert mit taxol |
-
1999
- 1999-06-28 GB GBGB9915069.0A patent/GB9915069D0/en not_active Ceased
-
2000
- 2000-06-28 EP EP00940633A patent/EP1189908B1/de not_active Expired - Lifetime
- 2000-06-28 AU AU55544/00A patent/AU775414B2/en not_active Ceased
- 2000-06-28 US US10/019,388 patent/US6852715B1/en not_active Expired - Fee Related
- 2000-06-28 JP JP2001507035A patent/JP2003503412A/ja active Pending
- 2000-06-28 DE DE60004669T patent/DE60004669T2/de not_active Expired - Fee Related
- 2000-06-28 AT AT00940633T patent/ATE247662T1/de not_active IP Right Cessation
- 2000-06-28 DK DK00940633T patent/DK1189908T3/da active
- 2000-06-28 KR KR1020017016857A patent/KR20020037730A/ko not_active Application Discontinuation
- 2000-06-28 MX MXPA02000173A patent/MXPA02000173A/es active IP Right Grant
- 2000-06-28 CA CA002377147A patent/CA2377147C/en not_active Expired - Fee Related
- 2000-06-28 IL IL14730700A patent/IL147307A0/xx not_active IP Right Cessation
- 2000-06-28 PT PT00940633T patent/PT1189908E/pt unknown
- 2000-06-28 ES ES00940633T patent/ES2202142T3/es not_active Expired - Lifetime
- 2000-06-28 WO PCT/GB2000/002473 patent/WO2001000627A1/en not_active Application Discontinuation
- 2000-06-28 CN CNB008121583A patent/CN1152881C/zh not_active Expired - Fee Related
- 2000-06-28 BR BR0012457-5A patent/BR0012457A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1189908A1 (de) | 2002-03-27 |
BR0012457A (pt) | 2002-04-02 |
ES2202142T3 (es) | 2004-04-01 |
WO2001000627A1 (en) | 2001-01-04 |
CA2377147A1 (en) | 2001-01-04 |
PT1189908E (pt) | 2003-11-28 |
AU775414B2 (en) | 2004-07-29 |
EP1189908B1 (de) | 2003-08-20 |
US6852715B1 (en) | 2005-02-08 |
DE60004669T2 (de) | 2004-07-08 |
IL147307A0 (en) | 2002-08-14 |
CN1371379A (zh) | 2002-09-25 |
KR20020037730A (ko) | 2002-05-22 |
ATE247662T1 (de) | 2003-09-15 |
AU5554400A (en) | 2001-01-31 |
CA2377147C (en) | 2009-04-07 |
DK1189908T3 (da) | 2003-10-06 |
GB9915069D0 (en) | 1999-08-25 |
CN1152881C (zh) | 2004-06-09 |
JP2003503412A (ja) | 2003-01-28 |
MXPA02000173A (es) | 2002-07-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200420542A (en) | A compound having TGF β inhibition activity and a medicinal composition containing the same | |
DE69827236D1 (en) | Matrix-metalloproteinase-hemmer | |
IL154272A (en) | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands | |
YU51400A (sh) | Derivati 2-piridilmetilamina, kao korisni fungicidi | |
GB9905075D0 (en) | Chemical compounds | |
PT804200E (pt) | Uso de derivados de noribogaina para tratamento de dependencia quimica em mamiferos | |
HUP0203422A2 (hu) | Foszfodiészteráz VII inhibitor hatású imidazolszármazékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
BG104569A (en) | Substituted 2-benzylamino-2-phenyl-acetamide compounds | |
AU541413B2 (en) | 2-(1,4-benzodioxan-2-ylalicyl)imidazoles | |
DE60004669D1 (de) | Indolocarbazolalkaloide aus einer marinen actinomycete | |
FI953784A0 (fi) | 3'-atsiridinoantrasykliinijohdannaiset | |
HUP0004317A2 (hu) | 5-HT1F agonisták | |
HUP9903526A2 (hu) | Pirimidinszármazékok és az ezeket tartalmazó gyógyszerkészítmények | |
ATE229538T1 (de) | 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose | |
AP1518A (en) | Novel octahydro-6, 10-dioxo-6h-pyridazino/1,2-a/ /1,2/diazepin-1-carboxylic acid derivatives, preparation method and use for preparing therapeutically active compounds. | |
TR200003877T2 (tr) | İnsan CD23 üretiminin ve TNF salınmasının ihhibitörleri olan hiydroxamic acid türevleri | |
JO1676B1 (en) | Extra compounds indinol II | |
AP2001002314A0 (en) | Substituted benzolactam compounds. | |
TW328083B (en) | New derivatives of β-methoxy acrylic acid, their preparation process and their use as pesticides | |
DK0504290T3 (da) | Inhibitorer af dihydrofylatreduktase fra Pneumocystis carinii | |
IL148590A0 (en) | Alkaloid compounds and pharmaceutical compositions containing the same | |
HUP0101505A2 (hu) | Barbitursavszármazékok és ezeket tartalmazó gyógyszerkészítmények csont- és porcbetegségek kezelésére és megelőzésére | |
TW353071B (en) | Chromene compounds with neutroleptic activity, their preparation and pharmaceutical compositions | |
DK0850217T3 (da) | Fremgangsmåde til fremstilling af arylalkynyl-N-hydroxy-carbamid-derivater med lipoxygenaseinhibitor-aktivitet |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |