DE3879191D1 - Purin-derivate mit pharmakologischer wirksamkeit. - Google Patents

Purin-derivate mit pharmakologischer wirksamkeit.

Info

Publication number: DE3879191D1
Authority: DE; Germany
Prior art keywords: pct; purine derivatives; pharmacological effectiveness; sec; date
Prior art date: 1987-12-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE8989902205T

Other languages

English (en)

Other versions

DE3879191T2 (de

Inventor

Ferraris Paolo Cornaglia

Riccardo Stradi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sigma Tau Industrie Farmaceutiche Riunite SpA

Original Assignee

CO PHARMA CORP

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-24

Filing date

1988-12-22

Publication date

1993-04-15

1988-12-22 Application filed by CO PHARMA CORP filed Critical CO PHARMA CORP

1993-04-15 Publication of DE3879191D1 publication Critical patent/DE3879191D1/de

1993-06-17 Application granted granted Critical

1993-06-17 Publication of DE3879191T2 publication Critical patent/DE3879191T2/de

2008-12-23 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DE8989902205T 1987-12-24 1988-12-22 Purin-derivate mit pharmakologischer wirksamkeit. Expired - Fee Related DE3879191T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT23218/87A IT1223604B (it)	1987-12-24	1987-12-24	Derivati purinici ad azione farmacologica
PCT/EP1988/001194 WO1989005818A1 (en)	1987-12-24	1988-12-22	Purine derivatives having pharmacological action

Publications (2)

Publication Number	Publication Date
DE3879191D1 true DE3879191D1 (de)	1993-04-15
DE3879191T2 DE3879191T2 (de)	1993-06-17

Family

ID=11205008

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8989902205T Expired - Fee Related DE3879191T2 (de)	1987-12-24	1988-12-22	Purin-derivate mit pharmakologischer wirksamkeit.

Country Status (8)

Country	Link
US (1)	US5110798A (de)
EP (1)	EP0346460B1 (de)
JP (1)	JP2868560B2 (de)
AT (1)	ATE86630T1 (de)
AU (1)	AU3052889A (de)
DE (1)	DE3879191T2 (de)
IT (1)	IT1223604B (de)
WO (1)	WO1989005818A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1241452B (it) *	1990-06-28	1994-01-17	Sigma Tau Ind Farmaceuti	Derivati oligopeptidici dell'ipoxantina dotati di attivita' immunomodulante e composizioni farmaceutiche che li contengono
US6110923A (en) *	1994-06-22	2000-08-29	Biochem Pharma Inc.	Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity
FR2753707B1 (fr) *	1996-09-23	1998-12-11		Complexes nucleopeptidiques, compositions cosmetologiques et pharmaceutiques les contenant et utilisations
TW202300178A (zh)	2021-03-18	2023-01-01	美商西根公司	內化的生物活性化合物偶聯物選擇性釋放藥物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5754157A (en) *	1980-09-19	1982-03-31	Nippon Kayaku Co Ltd	L-argininal derivative and its preparation
AU564576B2 (en) *	1981-09-24	1987-08-20	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Purine derivatives
DE3141923A1 (de) *	1981-10-22	1983-05-05	Kunz, Horst, Prof. Dr., 6500 Mainz	2(2-pyridyl)ethoxycarbonyl- und 2-(4-pyridyl)ethxycarbonyl-verbindungen und deren pyridiniumsalze
US4387049A (en) *	1982-02-22	1983-06-07	Smithkline Beckman Corporation	Adamantyl containing peptides
NL8202626A (nl) *	1982-06-29	1984-01-16	Stichting Rega V Z W	Derivaten van 9-(2-hydroxyethoxymethyl)guanine.

1987
- 1987-12-24 IT IT23218/87A patent/IT1223604B/it active
1988
- 1988-12-22 WO PCT/EP1988/001194 patent/WO1989005818A1/en active IP Right Grant
- 1988-12-22 AU AU30528/89A patent/AU3052889A/en not_active Abandoned
- 1988-12-22 EP EP89902205A patent/EP0346460B1/de not_active Expired - Lifetime
- 1988-12-22 US US07/397,457 patent/US5110798A/en not_active Expired - Lifetime
- 1988-12-22 DE DE8989902205T patent/DE3879191T2/de not_active Expired - Fee Related
- 1988-12-22 JP JP1502061A patent/JP2868560B2/ja not_active Expired - Fee Related
- 1988-12-22 AT AT89902205T patent/ATE86630T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0346460A1 (de)	1989-12-20
EP0346460B1 (de)	1993-03-10
IT1223604B (it)	1990-09-29
WO1989005818A1 (en)	1989-06-29
ATE86630T1 (de)	1993-03-15
JP2868560B2 (ja)	1999-03-10
US5110798A (en)	1992-05-05
AU3052889A (en)	1989-07-19
DE3879191T2 (de)	1993-06-17
IT8723218A0 (it)	1987-12-24
JPH02503006A (ja)	1990-09-20

Publication	Publication Date	Title
ES2128307T3 (es)	1999-05-16	Derivados de 1,4,7,10-tetraaza-ciclododecano monosustituidos en n, procedimiento para su preparacion y agentes farmaceuticos que los contienen.
PH24956A (en)	1990-12-26	Substituted amino-5,6,7,8-tetrahydronaphthyl-oxyacetic acids and their use as medicaments
FI882474A0 (fi)	1988-05-25	Nytt psykostimulerande aemne.
ATE145907T1 (de)	1996-12-15	Imidazo(1,2-a>pyridine
PT80820B (pt)	1988-04-21	Processo para a preparacao de derivados de 1,3-propilidenodifosfonato 2-substituidos
ES526673A0 (es)	1984-07-01	Procedimiento para la obtencion de 1,2,3,4-tetrahidropiridinas
DE68917934D1 (de)	1994-10-06	Fingerabdruck-reagenz.
DE3879191D1 (de)	1993-04-15	Purin-derivate mit pharmakologischer wirksamkeit.
DK154501C (da)	1989-04-10	5-amino-2,4,6-trijodisophthalsyre-bis-amid-derivater og deres salte med roentgenkontrastsyrer
FR2549049B1 (fr)	1986-06-20	Nouvelles amidines, leur procede de preparation et leur application therapeutique
ES2176183T3 (es)	2002-12-01	Procedimiento para la preparacion de tetraaza-macrociclos mono-sustituidos en n.
DK264687D0 (da)	1987-05-25	Substituerede 6-hydroxymethyl-carbapenem-antibiotika, deres fremstilling og anvendelse
ATE188217T1 (de)	2000-01-15	1,2,3,4,10,14b-hexahydrodibenzo-c,f)pyrazino-1, - a)azepino-derivate
SE7811455L (sv)	1979-07-02	2-imino-imidazolidin-derivat
ES523839A0 (es)	1984-04-01	Un procedimiento para la obtencion de sales de amino (e imino) acidos (alfa) w -sulfonicos n-sustituidos.
DK601888A (da)	1989-05-01	Anvendelse af 2-pyrimidinyl-1-piperazinderivater
DE3664634D1 (en)	1989-08-31	Substituted o-sulfonyl-glycosyl amides, method for their preparation and their use as mediacments
DE3664564D1 (en)	1989-08-31	4-amino-2-(imidazolidine-2-on-1-yl)-pyrimidine-5-carboxylic acid-(n-(3-trifluormethyl-phenyl)-amides)for antithrombotic prophylaxis and treatment and its use in the production of antithrombotic medicaments
PH21982A (en)	1988-05-02	N-(3-triflouromethyl-phenyl)-n'-propargylpiperazine and method of use thereof
IL101708A0 (en)	1992-12-30	Anti-fattening drugs
DK4389D0 (da)	1989-01-06	Isoxazoler med nootrop virkning
SE8006142L (sv)	1981-03-05	1,2,4-triazol-3-tioler
ATE60048T1 (de)	1991-02-15	Aminoverbindungen und diese enthaltende fungizide.
DE3167839D1 (en)	1985-01-31	Method for preparing n-(4-(((2,4-diamino-6-pteridinyl)-methyl)methylamino)benzoyl)glutamic acid
SE8702406D0 (sv)	1987-06-10	Benzoic acid derivatives

Legal Events

Date	Code	Title	Description
1994-04-07	8364	No opposition during term of opposition
1997-08-14	8327	Change in the person/name/address of the patent owner	Owner name: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.,
2008-10-16	8339	Ceased/non-payment of the annual fee