DE3871596D1 - Anwendung eines prostaglandins in mischung mit einem adrenergischen blocker zur verminderung des augen-innendruckes. - Google Patents
Anwendung eines prostaglandins in mischung mit einem adrenergischen blocker zur verminderung des augen-innendruckes.Info
- Publication number
- DE3871596D1 DE3871596D1 DE8888104999T DE3871596T DE3871596D1 DE 3871596 D1 DE3871596 D1 DE 3871596D1 DE 8888104999 T DE8888104999 T DE 8888104999T DE 3871596 T DE3871596 T DE 3871596T DE 3871596 D1 DE3871596 D1 DE 3871596D1
- Authority
- DE
- Germany
- Prior art keywords
- prostaglandin
- mixture
- eye
- intraocular pressure
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 150000003180 prostaglandins Chemical class 0.000 title abstract 5
- 239000000674 adrenergic antagonist Substances 0.000 title abstract 3
- 230000004410 intraocular pressure Effects 0.000 abstract 4
- 208000010412 Glaucoma Diseases 0.000 abstract 2
- 206010030043 Ocular hypertension Diseases 0.000 abstract 2
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3448487A | 1987-04-03 | 1987-04-03 |
Publications (3)
Publication Number | Publication Date |
---|---|
DE3871596D1 true DE3871596D1 (de) | 1992-07-09 |
DE3871596T2 DE3871596T2 (de) | 1993-01-21 |
DE3871596T3 DE3871596T3 (de) | 2000-09-07 |
Family
ID=21876714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3871596T Expired - Lifetime DE3871596T3 (de) | 1987-04-03 | 1988-03-28 | Anwendung eines Prostaglandins in Mischung mit einem adrenergischen Blocker zur Verminderung des Augen-Innendruckes. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0286903B2 (de) |
JP (1) | JP2726672B2 (de) |
AT (1) | ATE76750T1 (de) |
AU (1) | AU607981B2 (de) |
CA (1) | CA1314220C (de) |
DE (1) | DE3871596T3 (de) |
ES (1) | ES2042625T5 (de) |
GR (2) | GR3004794T3 (de) |
HU (1) | HU211835A9 (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1334168C (en) * | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
US5173507A (en) * | 1988-07-18 | 1992-12-22 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
US4994274A (en) * | 1989-07-27 | 1991-02-19 | Allergan, Inc. | Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using |
US5028624A (en) * | 1989-07-27 | 1991-07-02 | Allergan, Inc. | Intraocular pressure reducing 9,15-diacyl prostaglandins |
CA2021316C (en) * | 1989-07-27 | 2000-10-24 | Ming Fai Chan | Intraocular pressure reducing 11-acyl prostaglandins |
US5198545A (en) * | 1989-11-13 | 1993-03-30 | Allergan, Inc. | Pharmaceutical epinephrine-pilocarpine compounds and process of preparation thereof |
US5055467A (en) * | 1989-11-13 | 1991-10-08 | Allergan, Inc. | Pharmaceutical epinephrine-pilocarpine compounds |
US5011856A (en) * | 1990-03-12 | 1991-04-30 | Allergan, Inc. | Use of prostaglandin F3 α as an ocular hypotensive agent |
EP0458589B1 (de) * | 1990-05-22 | 1995-01-18 | R-Tech Ueno Ltd. | Behandlung von intraokularem Druck mit einer ophthalmischen synergistischen Kombination |
CA2042936C (en) * | 1990-05-22 | 2002-04-30 | Ryuji Ueno | Treatment of ocular hypertension with a synergistic combination for ophthalmic use |
ES2084771T3 (es) * | 1990-05-22 | 1996-05-16 | R Tech Ueno Ltd | Tratamiento de la hipertension ocular con la ayuda de una combinacion sinergica. |
US5238961A (en) * | 1990-06-14 | 1993-08-24 | Allergan, Inc. | Pgf 1-alcohols and their use as ocular hypotensives |
TW210287B (de) * | 1991-03-01 | 1993-08-01 | Kabushikaisha Ueno Seiyaku Oyo Kenkyujo | |
PT561073E (pt) * | 1992-03-19 | 2002-04-29 | R Tech Ueno Ltd | Tratamento da hipertensao ocular com beta-bloqueadores e derivados de acido prostanoico |
JPH06107547A (ja) * | 1992-10-01 | 1994-04-19 | Aarutetsuku Ueno:Kk | 眼科用組成物 |
ATE153855T1 (de) * | 1992-10-13 | 1997-06-15 | Alcon Lab Inc | Zusammensetzungen zur behandlung von glaukoma die prostaglandine und clonidinderivate enthalten |
US5574066A (en) * | 1992-10-28 | 1996-11-12 | Allergan | Intraocular pressure reducing 15-acyl prostaglandins |
SE9402816D0 (sv) * | 1994-08-24 | 1994-08-24 | Pharmacia Ab | Method and meams for drug administration |
US5698733A (en) * | 1994-09-30 | 1997-12-16 | Alcon Laboratories, Inc. | Use of 9-deoxy prostaglandin derivatives to treat glaucoma |
EP1049466B1 (de) * | 1998-01-23 | 2005-12-07 | Einar Stefansson | Carbonische anhydrase inhibitor zur steigerung des sauerstoffdrucks im sehnerv und retina |
CN1259051C (zh) * | 2001-04-19 | 2006-06-14 | 帝化制药株式会社 | 药物及药物试剂盒 |
TWI298257B (en) | 2001-05-31 | 2008-07-01 | Allergan Inc | Hypotensive lipid and timolol compositions and methods of using same |
AU2007200821A1 (en) * | 2001-05-31 | 2007-03-15 | Allergan, Inc. | Hypotensive lipid and timolol compositions and methods of using same |
TW200305424A (en) | 2002-01-29 | 2003-11-01 | Santen Pharmaceutical Co Ltd | Glaucoma-treating agent comprising bunazosin and prostaglandin |
WO2004019951A1 (ja) * | 2002-08-29 | 2004-03-11 | Santen Pharmaceutical Co., Ltd. | Rhoキナーゼ阻害剤とプロスタグランジン類からなる緑内障治療剤 |
KR101103141B1 (ko) | 2002-11-18 | 2012-01-04 | 산텐 세이야꾸 가부시키가이샤 | Rho 키나아제 억제제와 β 차단약으로 이루어진 녹내장치료제 |
US7186744B2 (en) * | 2003-11-13 | 2007-03-06 | Allergan, Inc. | Prostamides for the treatment of glaucoma and related diseases |
PL1905452T3 (pl) | 2005-07-12 | 2013-11-29 | Kowa Co | Środek do zapobiegania lub leczenia jaskry |
EP2127638A1 (de) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Verfahren und Zusammensetzung zur Behandlung von Augenhochdruck und Glaukom |
WO2011034192A1 (ja) * | 2009-09-17 | 2011-03-24 | 千寿製薬株式会社 | ラタノプロストを含有する水性点眼剤、並びにラタノプロストの樹脂への吸着の抑制方法 |
US9061034B2 (en) | 2010-07-29 | 2015-06-23 | Allergan, Inc. | Preservative free bimatoprost and timolol solutions |
ES2708451T3 (es) | 2010-07-29 | 2019-04-09 | Allergan Inc | Soluciones de bimatoprost y timolol sin conservantes |
US20130310370A1 (en) | 2011-02-04 | 2013-11-21 | Kowa Co., Ltd. | Drug therapy for preventing or treating glaucoma |
TWI643619B (zh) * | 2012-07-13 | 2018-12-11 | 日商參天製藥股份有限公司 | 一種用於預防或治療青光眼或高眼壓症、或降低眼壓之醫藥組合物及其用途 |
WO2018033854A1 (en) | 2016-08-15 | 2018-02-22 | Santen Pharmaceutical Co., Ltd. | Ophthalmic composition and a method for treating ocular hypertension and glaucoma |
TWI788484B (zh) | 2017-12-21 | 2023-01-01 | 日商參天製藥股份有限公司 | 賽佩普斯特(Sepetaprost)及Rho激酶抑制劑之組合醫藥 |
TW201927303A (zh) | 2017-12-21 | 2019-07-16 | 日商參天製藥股份有限公司 | 歐米德尼培(Omidenepag)之組合 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4454154A (en) * | 1981-06-23 | 1984-06-12 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
US4599353A (en) * | 1982-05-03 | 1986-07-08 | The Trustees Of Columbia University In The City Of New York | Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma |
DE3300933A1 (de) * | 1983-01-13 | 1984-07-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von d,l- und d-carazolol als antiglaukommittel sowie arzneimittel, die diese stoffe enthalten |
EP0242580B1 (de) * | 1986-03-13 | 1993-04-28 | The Trustees Of Columbia University In The City Of New York | Verwendung von A-, B- und C-Prostaglandinen und deren Derivaten zur Behandlung von Augen-Hypertension und Glaukom |
-
1988
- 1988-03-28 DE DE3871596T patent/DE3871596T3/de not_active Expired - Lifetime
- 1988-03-28 EP EP88104999A patent/EP0286903B2/de not_active Expired - Lifetime
- 1988-03-28 AT AT88104999T patent/ATE76750T1/de not_active IP Right Cessation
- 1988-03-28 ES ES88104999T patent/ES2042625T5/es not_active Expired - Lifetime
- 1988-03-30 AU AU13870/88A patent/AU607981B2/en not_active Expired
- 1988-03-30 CA CA000562902A patent/CA1314220C/en not_active Expired - Lifetime
- 1988-04-01 JP JP63081167A patent/JP2726672B2/ja not_active Expired - Lifetime
-
1992
- 1992-06-04 GR GR920401036T patent/GR3004794T3/el unknown
-
1995
- 1995-06-28 HU HU95P/P00519P patent/HU211835A9/hu unknown
-
2000
- 2000-06-16 GR GR20000401411T patent/GR3033721T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA1314220C (en) | 1993-03-09 |
JP2726672B2 (ja) | 1998-03-11 |
GR3004794T3 (de) | 1993-04-28 |
JPS63313728A (ja) | 1988-12-21 |
DE3871596T3 (de) | 2000-09-07 |
GR3033721T3 (en) | 2000-10-31 |
ES2042625T5 (es) | 2000-07-16 |
AU607981B2 (en) | 1991-03-21 |
HU211835A9 (en) | 1995-12-28 |
ES2042625T3 (es) | 1993-12-16 |
EP0286903A1 (de) | 1988-10-19 |
DE3871596T2 (de) | 1993-01-21 |
AU1387088A (en) | 1988-10-06 |
ATE76750T1 (de) | 1992-06-15 |
EP0286903B2 (de) | 2000-03-29 |
EP0286903B1 (de) | 1992-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8380 | Miscellaneous part iii |
Free format text: DIE PATENTINHABER LAUTEN RICHTIG: KABI PHARMACIA AB, UPPSALA, SE PHARMACIA AB,UPPSALA, SE |
|
8363 | Opposition against the patent | ||
8328 | Change in the person/name/address of the agent |
Free format text: DERZEIT KEIN VERTRETER BESTELLT |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF |
|
8366 | Restricted maintained after opposition proceedings |