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CY1119942T1 - Μεθοδοι θεραπειας της ψωριασης χρησιμοποιωντας ανταγωνιστες της il-17 - Google Patents

Μεθοδοι θεραπειας της ψωριασης χρησιμοποιωντας ανταγωνιστες της il-17

Info

Publication number
CY1119942T1
CY1119942T1 CY20181100220T CY181100220T CY1119942T1 CY 1119942 T1 CY1119942 T1 CY 1119942T1 CY 20181100220 T CY20181100220 T CY 20181100220T CY 181100220 T CY181100220 T CY 181100220T CY 1119942 T1 CY1119942 T1 CY 1119942T1
Authority
CY
Cyprus
Prior art keywords
treatment
competitors
philosophy
methods
antibody
Prior art date
Application number
CY20181100220T
Other languages
English (en)
Inventor
Achim Guettner
Matthias Machacek
Charis Papavassilis
Oliver Sander
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44759699&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1119942(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1119942T1 publication Critical patent/CY1119942T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η περιγραφή αναφέρεται σε σχήματα για την θεραπεία της ψωρίασης, τα οποία χρησιμοποιούν μια θεραπευτικώς δραστική ποσότητα ενός ανταγωνιστή της IL-17, π.χ. ένα μόριο που συνδέεται με την IL-17, ένα αντίσωμα έναντι της IL-17, όπως το αντίσωμα σεκουκινουμάμπη, ή ένα μόριο που συνδέεται με τον υποδοχέα της IL-17, π.χ. ένα αντίσωμα του υποδοχέα της IL-17.
CY20181100220T 2010-10-08 2018-02-22 Μεθοδοι θεραπειας της ψωριασης χρησιμοποιωντας ανταγωνιστες της il-17 CY1119942T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39138810P 2010-10-08 2010-10-08
PCT/EP2011/067522 WO2012045848A1 (en) 2010-10-08 2011-10-07 Methods of treating psoriasis using il-17 antagonists

Publications (1)

Publication Number Publication Date
CY1119942T1 true CY1119942T1 (el) 2018-12-12

Family

ID=44759699

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20181100220T CY1119942T1 (el) 2010-10-08 2018-02-22 Μεθοδοι θεραπειας της ψωριασης χρησιμοποιωντας ανταγωνιστες της il-17

Country Status (27)

Country Link
US (6) US9717791B2 (el)
EP (4) EP4137514A1 (el)
JP (2) JP5537740B2 (el)
KR (3) KR101620771B1 (el)
CN (2) CN103154031A (el)
AU (1) AU2011311482B2 (el)
BR (1) BR112013008501A2 (el)
CA (1) CA2813900C (el)
CL (1) CL2013000930A1 (el)
CY (1) CY1119942T1 (el)
DK (1) DK2625199T3 (el)
ES (1) ES2660770T3 (el)
HK (1) HK1247932A1 (el)
HR (1) HRP20180301T1 (el)
HU (1) HUE038334T2 (el)
IL (1) IL225310A (el)
LT (1) LT2625199T (el)
MA (1) MA34646B1 (el)
MX (1) MX356279B (el)
NO (1) NO2625199T3 (el)
PL (1) PL2625199T3 (el)
PT (1) PT2625199T (el)
RU (2) RU2665954C1 (el)
SG (1) SG188979A1 (el)
SI (1) SI2625199T1 (el)
TW (2) TWI564022B (el)
WO (1) WO2012045848A1 (el)

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US7833527B2 (en) 2006-10-02 2010-11-16 Amgen Inc. Methods of treating psoriasis using IL-17 Receptor A antibodies
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
WO2011088120A1 (en) 2010-01-15 2011-07-21 Amgen Inc. Antibody formulation and therapeutic regimens
EP3546483A1 (en) 2010-05-20 2019-10-02 Ablynx N.V. Biological materials related to her3
UA117218C2 (uk) 2011-05-05 2018-07-10 Мерк Патент Гмбх Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
US20150064193A1 (en) * 2011-11-21 2015-03-05 Novartis Ag Methods of treating psoriatic arthritis (psa) using il-17 antagonists and psa response or non-response alleles
KR20150128858A (ko) * 2013-03-15 2015-11-18 암젠 인크 항-il-23 항체를 사용한 건선의 치료 방법
CN105307675A (zh) * 2013-03-15 2016-02-03 美国安进公司 使用抗il23抗体治疗克罗恩氏病的方法
EP3033107A1 (en) * 2013-08-15 2016-06-22 Novartis AG Methods of treating generalized pustular psoriasis (gpp) using il-17 antagonists
EP3088000A4 (en) * 2013-12-27 2017-08-09 Osaka University Vaccine targeting il-17a
RU2577228C2 (ru) * 2014-03-14 2016-03-10 Закрытое Акционерное Общество "Биокад" Анти-il-17-антитела, способ их получения и способ применения
JP6596014B2 (ja) * 2014-03-31 2019-10-23 アムジェン ケー・エー，インコーポレイテッド 爪および頭皮乾癬の治療方法
US11548940B2 (en) 2014-05-15 2023-01-10 Rani Therapeutics, Llc Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
CA3198322A1 (en) 2014-05-15 2015-11-19 Rani Therapeutics, Llc Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins
CA2962910C (en) * 2014-08-26 2022-11-22 Kirin-Amgen, Inc. Method for treating psoriasis patient which received anti-tnf-alpha antibody therapy
ES2981697T3 (es) * 2014-09-10 2024-10-10 Novartis Ag Uso de antagonistas de IL-17 para inhibir la progresión del daño estructural en pacientes con artritis psoriásica
AR103173A1 (es) * 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
AR103172A1 (es) 2014-12-22 2017-04-19 Novartis Ag Reducción selectiva de residuos de cisteina en anticuerpos il-17
AU2016226414B2 (en) 2015-03-02 2021-09-09 180 Therapeutics Lp Method of treating a localized fibrotic disorder using an IL-33 antagonist
EP3167892A1 (en) 2015-11-10 2017-05-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for preventing or treating imflammatory bowel diseases
RU2754683C2 (ru) * 2015-10-27 2021-09-06 Юсб Биофарма Срл Способы лечения с использованием анти-il-17a антител
US20190194311A1 (en) * 2016-07-19 2019-06-27 Novartis Ag Methods of treating new-onset plaque type psoriasis using il-17 antagonists
WO2018096467A1 (en) * 2016-11-28 2018-05-31 Novartis Ag Methods of treating acne using interleukin-17 (il-17) antagonists
WO2018158741A1 (en) * 2017-03-03 2018-09-07 Novartis Ag Psoriasis disease modification following long-term treatment with an il-17 antagonist
CN111032691A (zh) * 2017-08-23 2020-04-17 伊莱利利公司 生殖器银屑病的治疗
TWI725532B (zh) * 2018-09-11 2021-04-21 美商美國禮來大藥廠 治療牛皮癬之方法
CN114127108A (zh) 2019-07-30 2022-03-01 江苏恒瑞医药股份有限公司 Il-17拮抗剂治疗自身免疫疾病的方法
TW202246329A (zh) * 2021-03-03 2022-12-01 大陸商蘇州盛迪亞生物醫藥有限公司 抗il-17抗體治療自體免疫性疾病和炎症的方法
WO2023186174A1 (en) * 2022-04-01 2023-10-05 Zai Lab (Shanghai) Co., Ltd. Topical formulation comprising an il-17a binding molecule and uses thereof
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Also Published As

Publication number Publication date
WO2012045848A1 (en) 2012-04-12
US20210113688A1 (en) 2021-04-22
JP5537740B2 (ja) 2014-07-02
NO2625199T3 (el) 2018-04-21
US20170304439A1 (en) 2017-10-26
TW201630625A (zh) 2016-09-01
EP2625199A1 (en) 2013-08-14
RU2591083C2 (ru) 2016-07-10
EP4137514A1 (en) 2023-02-22
CA2813900C (en) 2017-01-10
KR20150018595A (ko) 2015-02-23
KR101620771B1 (ko) 2016-05-12
SI2625199T1 (en) 2018-03-30
LT2625199T (lt) 2018-03-12
US20200171147A1 (en) 2020-06-04
AU2011311482A1 (en) 2013-04-04
TWI548419B (zh) 2016-09-11
CN107029234A (zh) 2017-08-11
US20130202610A1 (en) 2013-08-08
ES2660770T3 (es) 2018-03-26
JP2013543501A (ja) 2013-12-05
AU2011311482B2 (en) 2014-05-29
TWI564022B (zh) 2017-01-01
SG188979A1 (en) 2013-05-31
EP3299390A1 (en) 2018-03-28
MX356279B (es) 2018-05-22
JP2014114288A (ja) 2014-06-26
MA34646B1 (fr) 2013-11-02
EP3792281A1 (en) 2021-03-17
HUE038334T2 (hu) 2018-10-29
US9717791B2 (en) 2017-08-01
CN103154031A (zh) 2013-06-12
RU2665954C1 (ru) 2018-09-05
HK1247932A1 (zh) 2018-10-05
CL2013000930A1 (es) 2014-03-28
HRP20180301T1 (hr) 2018-03-23
US11534490B2 (en) 2022-12-27
CA2813900A1 (en) 2012-04-12
TW201216984A (en) 2012-05-01
PL2625199T3 (pl) 2018-04-30
PT2625199T (pt) 2018-02-28
US10583190B2 (en) 2020-03-10
US20230321231A1 (en) 2023-10-12
IL225310A0 (en) 2013-06-27
KR20130110179A (ko) 2013-10-08
DK2625199T3 (en) 2018-02-26
KR20140097566A (ko) 2014-08-06
BR112013008501A2 (pt) 2016-08-16
EP2625199B1 (en) 2017-11-22
MX2013003916A (es) 2013-06-03
US20210162044A1 (en) 2021-06-03
IL225310A (en) 2016-10-31
RU2013120957A (ru) 2014-11-20

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