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CY1113190T1 - Μεθοδος αγωγης της αιμολυτικης νοσου - Google Patents

Μεθοδος αγωγης της αιμολυτικης νοσου

Info

Publication number
CY1113190T1
CY1113190T1 CY20121100783T CY121100783T CY1113190T1 CY 1113190 T1 CY1113190 T1 CY 1113190T1 CY 20121100783 T CY20121100783 T CY 20121100783T CY 121100783 T CY121100783 T CY 121100783T CY 1113190 T1 CY1113190 T1 CY 1113190T1
Authority
CY
Cyprus
Prior art keywords
treatment
hemolytic disease
hemolytic
complement
binds
Prior art date
Application number
CY20121100783T
Other languages
English (en)
Inventor
Leonard Bell
Russell P Rother
Original Assignee
Alexion Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34808492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1113190(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alexion Pharmaceuticals, Inc. filed Critical Alexion Pharmaceuticals, Inc.
Publication of CY1113190T1 publication Critical patent/CY1113190T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παροξυσμική νυκτερινή αιμοσφαιρινουρία ή άλλες αιμολυτικές νόσοι υποβάλλονται σε αγωγή δια της χρήσεως μίας ενώσεως που δεσμεύεται σε ή κατά τα άλλα καταστέλλει τη δημιουργία και/ή τη δράση ενός ή περισσότερων συνιστωσών του συμπληρώματος, όπως, για παράδειγμα, ενός αντισώματος ανασταλτικού του συμπληρώματος.
CY20121100783T 2004-02-03 2012-08-30 Μεθοδος αγωγης της αιμολυτικης νοσου CY1113190T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/771,552 US20050169921A1 (en) 2004-02-03 2004-02-03 Method of treating hemolytic disease
EP05712607A EP1720571B9 (en) 2004-02-03 2005-02-03 Method of treating hemolytic disease

Publications (1)

Publication Number Publication Date
CY1113190T1 true CY1113190T1 (el) 2016-04-13

Family

ID=34808492

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100783T CY1113190T1 (el) 2004-02-03 2012-08-30 Μεθοδος αγωγης της αιμολυτικης νοσου

Country Status (17)

Country Link
US (5) US20050169921A1 (el)
EP (7) EP2522362A1 (el)
JP (5) JP2007520494A (el)
KR (1) KR101197799B1 (el)
CN (4) CN103977402A (el)
AU (1) AU2005209854B2 (el)
CA (1) CA2554632A1 (el)
CY (1) CY1113190T1 (el)
DK (1) DK1720571T3 (el)
ES (1) ES2389093T3 (el)
HK (1) HK1094950A1 (el)
IL (2) IL177003A0 (el)
NZ (1) NZ549328A (el)
PL (1) PL1720571T3 (el)
PT (1) PT1720571E (el)
SI (1) SI1720571T1 (el)
WO (1) WO2005074607A2 (el)

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US7083786B2 (en) 1997-04-03 2006-08-01 Jensenius Jens Chr MASP-2, a complement-fixing enzyme, and uses for it
US20050271660A1 (en) 2002-09-06 2005-12-08 Alexion Pharmaceuticals, Inc. Nebulization of monoclonal antibodies for treating pulmonary diseases
NZ538384A (en) * 2002-09-06 2009-04-30 Alexion Pharma Inc Treatment for asthma using a compound which binds to or otherwise blocks the generation and/or activity of one or more complement components reptors, such as, C5a receptors
US9415102B2 (en) 2002-09-06 2016-08-16 Alexion Pharmaceuticals, Inc. High concentration formulations of anti-C5 antibodies
US20050169921A1 (en) * 2004-02-03 2005-08-04 Leonard Bell Method of treating hemolytic disease
US20070116710A1 (en) * 2004-02-03 2007-05-24 Leonard Bell Methods of treating hemolytic anemia
CA2566716C (en) * 2004-05-14 2014-12-23 Alexion Pharmaceuticals, Inc. Prolongation of survival of an allograft by inhibiting complement activity
US8840893B2 (en) 2004-06-10 2014-09-23 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
US7919094B2 (en) * 2004-06-10 2011-04-05 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
WO2006107708A1 (en) * 2005-04-04 2006-10-12 Alexion Pharmaceuticals, Inc. Treatment of disease caused by excess free hemoglobin
MY151064A (en) * 2005-11-04 2014-03-31 Genentech Inc Use of complement pathway inhibitors to treat ocular diseases
EP1988882B1 (en) * 2006-03-02 2014-12-17 Alexion Pharmaceuticals, Inc. Prolongation of survival of an allograft by inhibiting complement activity
HUE030105T2 (en) * 2006-03-15 2017-04-28 Alexion Pharma Inc Treatment of paroxysmal nocturnal hemoglobin uptake with complement inhibitor
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US20110124019A1 (en) * 2009-11-25 2011-05-26 The Charlotte-Mecklenburg Hospital Authority Method of using carbonic anhydrase to detect hemolysis
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
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JP6030452B2 (ja) 2010-11-30 2016-11-24 中外製薬株式会社 複数分子の抗原に繰り返し結合する抗原結合分子
AU2015230852B2 (en) * 2011-03-08 2017-09-14 Alexion Pharmaceuticals, Inc. High concentration antibody formulations
US9644035B2 (en) 2011-04-08 2017-05-09 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
EP3287142B1 (en) * 2011-04-08 2021-08-04 University Of Leicester Methods for treating conditions associated with masp-2 dependent complement activation
US9051365B2 (en) 2011-12-21 2015-06-09 Novartis Ag Antibodies that bind factor P
WO2013137912A2 (en) * 2012-03-16 2013-09-19 Alexion Pharmaceuticals, Inc. Methods of distributing complement-inhibiting drugs to patients receiving a complement inhibitor
JP6366571B2 (ja) * 2012-04-06 2018-08-01 オメロス コーポレーション 発作性夜間血色素尿症の治療のためにｍａｓｐ−１、ｍａｓｐ−２および／またはｍａｓｐ−３を阻害する組成物および方法
US9579360B2 (en) * 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis
EP3473272A1 (en) 2013-03-29 2019-04-24 Alexion Pharmaceuticals, Inc. Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5
ES2650917T3 (es) 2013-08-07 2018-01-23 Alexion Pharmaceuticals, Inc. Proteínas biomarcadoras del síndrome urémico hemolítico atípico (SUHA)
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RU2718850C2 (ru) 2013-10-17 2020-04-15 Омерос Корпорейшн Способы лечения состояний, ассоциированных с masp-2-зависимой активацией комплемента
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CA3101987A1 (en) 2018-05-30 2019-12-05 The Regents Of The University Of California Microfluidic filter device and method for dissociation of tissue and cell aggregates and enrichment of single cells
KR20240115904A (ko) 2018-08-01 2024-07-26 추가이 세이야쿠 가부시키가이샤 C5-관련 질환의 치료 또는 예방용 의약 조성물 및 c5-관련 질환을 치료 또는 예방하기 위한 방법
JP7437261B2 (ja) 2019-07-31 2024-02-22 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト 抗ｃ５抗体クロバリマブの使用によるｃ５関連疾患の治療または予防のための薬用量および投与レジメン
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Also Published As

Publication number Publication date
AU2005209854B2 (en) 2011-01-20
SI1720571T1 (sl) 2012-10-30
CA2554632A1 (en) 2005-08-18
US20100068202A1 (en) 2010-03-18
PT1720571E (pt) 2012-08-29
JP2015083611A (ja) 2015-04-30
CN103977403A (zh) 2014-08-13
US20050169921A1 (en) 2005-08-04
PL1720571T3 (pl) 2012-11-30
EP1720571B9 (en) 2012-10-24
CN1938047A (zh) 2007-03-28
KR20070009996A (ko) 2007-01-19
EP2522364A1 (en) 2012-11-14
ES2389093T3 (es) 2012-10-23
KR101197799B9 (ko) 2024-02-08
CN103446584A (zh) 2013-12-18
US20120308559A1 (en) 2012-12-06
CN103977402A (zh) 2014-08-13
EP1720571A2 (en) 2006-11-15
JP2007520494A (ja) 2007-07-26
US20050191298A1 (en) 2005-09-01
EP2522362A1 (en) 2012-11-14
EP1720571B1 (en) 2012-06-13
WO2005074607A3 (en) 2006-09-14
EP2522361A1 (en) 2012-11-14
JP2017057234A (ja) 2017-03-23
EP2520311A3 (en) 2012-11-14
EP2520311A2 (en) 2012-11-07
DK1720571T3 (da) 2012-09-03
JP2011126917A (ja) 2011-06-30
WO2005074607A2 (en) 2005-08-18
AU2005209854A1 (en) 2005-08-18
EP1720571A4 (en) 2008-11-19
JP2013213044A (ja) 2013-10-17
JP5873047B2 (ja) 2016-03-01
NZ549328A (en) 2010-12-24
IL177003A0 (en) 2006-12-10
HK1094950A1 (en) 2007-04-20
US20110086040A1 (en) 2011-04-14
KR101197799B1 (ko) 2012-11-05
EP2910253A1 (en) 2015-08-26
EP2522363A1 (en) 2012-11-14
IL240410A0 (en) 2015-09-24

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