CY1111547T1 - Συνδυασμος zd6474 και πεμετρεξεδης - Google Patents
Συνδυασμος zd6474 και πεμετρεξεδηςInfo
- Publication number
- CY1111547T1 CY1111547T1 CY20111100546T CY111100546T CY1111547T1 CY 1111547 T1 CY1111547 T1 CY 1111547T1 CY 20111100546 T CY20111100546 T CY 20111100546T CY 111100546 T CY111100546 T CY 111100546T CY 1111547 T1 CY1111547 T1 CY 1111547T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pemetrexed
- human
- combination
- antiangiogenic
- warm
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σε μία μέθοδο για την παραγωγή μίας αντιαγγειογόνου επίδρασης και/ή επίδρασης μείωσης της αγγειακής διαπερατότητας σε ένα θερμόαιμο ζώο όπως ένας άνθρωπος, που υποβάλλεται σε θεραπευτική αντιμετώπιση προαιρετικά με ιοντίζουσα ακτινοβολία, συγκεκριμένα μία μέθοδο για τη θεραπευτική αντιμετώπιση ενός καρκίνου, συγκεκριμένα ενός καρκίνου περιλαμβανομένου ενός στερεού όγκου, που περιλαμβάνει τη χορήγηση ZD6474 σε συνδυασμό με πεμετρεξέδη σε μία φαρμακευτική σύνθεση που περιλαμβάνει ZD6474 και πεμετρεξέδη• σε ένα συνδυαστικό προϊόν που περιλαμβάνει ZD6474 και πεμετρεξέδη για χρήση σε μία θεραπευτική αντιμετώπιση του σώματος ενός ανθρώπου ή ενός ζώου με θεραπεία• σε ένα κιτ που περιλαμβάνει ZD6474 και πεμετρεξέδη• στη χρήση ZD6474 και πεμετρεξέδης στην παρασκευή ενός φαρμακευτικού μέσου για χρήση στην παραγωγή μίας αντιαγγειογόνου επίδρασης και/ή επίδρασης μείωσης της αγγειακής διαπερατότητας σε ένα θερμόαιμο ζώο, όπως σε έναν άνθρωπο, το οποίο υποβάλλεται προαιρετικά σε θεραπεία με ιονίζουσα ακτινοβολία.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0526121A GB0526121D0 (en) | 2005-12-22 | 2005-12-22 | Combination therapy |
| GB0610706A GB0610706D0 (en) | 2006-05-31 | 2006-05-31 | Combination therapy |
| EP06820566A EP1971338B8 (en) | 2005-12-22 | 2006-12-19 | Combination of zd6474 and pemetrexed |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111547T1 true CY1111547T1 (el) | 2015-08-05 |
Family
ID=37814151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20111100546T CY1111547T1 (el) | 2005-12-22 | 2011-06-08 | Συνδυασμος zd6474 και πεμετρεξεδης |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20080269261A1 (el) |
| EP (1) | EP1971338B8 (el) |
| JP (1) | JP5167144B2 (el) |
| KR (1) | KR20080079675A (el) |
| AT (1) | ATE500832T1 (el) |
| AU (1) | AU2006328189B2 (el) |
| BR (1) | BRPI0620140A2 (el) |
| CA (1) | CA2631764A1 (el) |
| CY (1) | CY1111547T1 (el) |
| DE (1) | DE602006020621D1 (el) |
| DK (1) | DK1971338T3 (el) |
| HK (1) | HK1123186A1 (el) |
| HR (1) | HRP20110360T1 (el) |
| IL (1) | IL191796A0 (el) |
| NO (1) | NO20082567L (el) |
| NZ (1) | NZ568811A (el) |
| PL (1) | PL1971338T3 (el) |
| PT (1) | PT1971338E (el) |
| SI (1) | SI1971338T1 (el) |
| WO (1) | WO2007071958A2 (el) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0008269D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
| GB0126879D0 (en) * | 2001-11-08 | 2002-01-02 | Astrazeneca Ab | Combination therapy |
| GB0218526D0 (en) * | 2002-08-09 | 2002-09-18 | Astrazeneca Ab | Combination therapy |
| GB0223380D0 (en) * | 2002-10-09 | 2002-11-13 | Astrazeneca Ab | Combination therapy |
| CA2514227C (en) * | 2003-02-13 | 2011-08-09 | Astrazeneca Ab | Combination therapy of zd6474 with 5-fu or/and cpt-11 |
| AU2004255022B2 (en) * | 2003-07-10 | 2007-08-23 | Astrazeneca Ab | Use of the quinazoline derivative ZD6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability |
| GB0318422D0 (en) * | 2003-08-06 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| KR20070072543A (ko) * | 2004-09-27 | 2007-07-04 | 아스트라제네카 아베 | Ｚｄ6474 및 이마티닙을 포함하는 병합법 |
| GB0424339D0 (en) * | 2004-11-03 | 2004-12-08 | Astrazeneca Ab | Combination therapy |
| NZ568811A (en) * | 2005-12-22 | 2011-06-30 | Astrazeneca Ab | Combination of ZD6474 and pemetrexed for treating cancer and the like |
| PT1965801E (pt) * | 2005-12-22 | 2011-05-25 | Astrazeneca Ab | Combina??o de azd2171 e pemetrexed |
| EP2066353B1 (en) * | 2006-09-29 | 2013-01-02 | AstraZeneca AB | Combination of zd6474 and bevacizumab for cancer therapy |
| US20090221615A1 (en) * | 2008-02-29 | 2009-09-03 | Guru Reddy | Combination anti-cancer agents |
| ES2727273T3 (es) | 2010-03-08 | 2019-10-15 | Spectrum Pharmaceuticals Inc | Terapias inhibidoras de la autofagia basadas en tioxantina para tratar el cáncer |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE554750T1 (de) * | 1997-03-05 | 2012-05-15 | Sugen Inc | Hydrophobe pharmazeutische wirkstoffe enthaltende zubereitungen |
| GB0008269D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
| US7001911B2 (en) * | 2000-06-28 | 2006-02-21 | Bristol-Myers Squibb Company | Fused cyclic modulators of nuclear hormone receptor function |
| AU9254801A (en) * | 2000-07-28 | 2002-02-13 | Sloan Kettering Inst Cancer | Methods for treating cell proliferative disorders and viral infections |
| GB0126879D0 (en) * | 2001-11-08 | 2002-01-02 | Astrazeneca Ab | Combination therapy |
| WO2004014383A1 (en) * | 2002-08-09 | 2004-02-19 | Astrazeneca Ab | Combination of zd6474, an inhibitor of the vascular endothelial growth factor receptor, with radiotherapy in the treatment of cancer |
| GB0218526D0 (en) * | 2002-08-09 | 2002-09-18 | Astrazeneca Ab | Combination therapy |
| GB0223380D0 (en) * | 2002-10-09 | 2002-11-13 | Astrazeneca Ab | Combination therapy |
| CA2514227C (en) * | 2003-02-13 | 2011-08-09 | Astrazeneca Ab | Combination therapy of zd6474 with 5-fu or/and cpt-11 |
| AU2004255022B2 (en) * | 2003-07-10 | 2007-08-23 | Astrazeneca Ab | Use of the quinazoline derivative ZD6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability |
| KR20070072543A (ko) * | 2004-09-27 | 2007-07-04 | 아스트라제네카 아베 | Ｚｄ6474 및 이마티닙을 포함하는 병합법 |
| GB0424339D0 (en) * | 2004-11-03 | 2004-12-08 | Astrazeneca Ab | Combination therapy |
| NZ568811A (en) * | 2005-12-22 | 2011-06-30 | Astrazeneca Ab | Combination of ZD6474 and pemetrexed for treating cancer and the like |
| PT1965801E (pt) * | 2005-12-22 | 2011-05-25 | Astrazeneca Ab | Combina??o de azd2171 e pemetrexed |
| EP2066353B1 (en) * | 2006-09-29 | 2013-01-02 | AstraZeneca AB | Combination of zd6474 and bevacizumab for cancer therapy |
-
2006
- 2006-12-19 NZ NZ568811A patent/NZ568811A/en not_active IP Right Cessation
- 2006-12-19 DE DE602006020621T patent/DE602006020621D1/de active Active
- 2006-12-19 WO PCT/GB2006/004750 patent/WO2007071958A2/en active Application Filing
- 2006-12-19 BR BRPI0620140-7A patent/BRPI0620140A2/pt not_active Application Discontinuation
- 2006-12-19 SI SI200630997T patent/SI1971338T1/sl unknown
- 2006-12-19 AT AT06820566T patent/ATE500832T1/de active
- 2006-12-19 PT PT06820566T patent/PT1971338E/pt unknown
- 2006-12-19 AU AU2006328189A patent/AU2006328189B2/en not_active Ceased
- 2006-12-19 DK DK06820566.5T patent/DK1971338T3/da active
- 2006-12-19 JP JP2008546586A patent/JP5167144B2/ja not_active Expired - Fee Related
- 2006-12-19 EP EP06820566A patent/EP1971338B8/en active Active
- 2006-12-19 PL PL06820566T patent/PL1971338T3/pl unknown
- 2006-12-19 US US12/158,264 patent/US20080269261A1/en not_active Abandoned
- 2006-12-19 CA CA002631764A patent/CA2631764A1/en not_active Abandoned
- 2006-12-19 KR KR1020087016946A patent/KR20080079675A/ko not_active Application Discontinuation
-
2008
- 2008-05-28 IL IL191796A patent/IL191796A0/en unknown
- 2008-06-02 NO NO20082567A patent/NO20082567L/no not_active Application Discontinuation
-
2009
- 2009-01-14 HK HK09100369.4A patent/HK1123186A1/xx not_active IP Right Cessation
-
2010
- 2010-09-28 US US12/892,478 patent/US20110212978A1/en not_active Abandoned
-
2011
- 2011-05-16 HR HR20110360T patent/HRP20110360T1/hr unknown
- 2011-06-08 CY CY20111100546T patent/CY1111547T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006328189B2 (en) | 2010-01-21 |
| JP2009520783A (ja) | 2009-05-28 |
| US20080269261A1 (en) | 2008-10-30 |
| NZ568811A (en) | 2011-06-30 |
| CA2631764A1 (en) | 2007-06-28 |
| BRPI0620140A2 (pt) | 2011-11-01 |
| US20110212978A1 (en) | 2011-09-01 |
| DK1971338T3 (da) | 2011-05-23 |
| WO2007071958A2 (en) | 2007-06-28 |
| WO2007071958A3 (en) | 2008-03-27 |
| NO20082567L (no) | 2008-07-31 |
| EP1971338B1 (en) | 2011-03-09 |
| AU2006328189A1 (en) | 2007-06-28 |
| EP1971338B8 (en) | 2011-09-21 |
| DE602006020621D1 (de) | 2011-04-21 |
| ATE500832T1 (de) | 2011-03-15 |
| SI1971338T1 (sl) | 2011-06-30 |
| PT1971338E (pt) | 2011-05-09 |
| HRP20110360T1 (hr) | 2011-06-30 |
| JP5167144B2 (ja) | 2013-03-21 |
| KR20080079675A (ko) | 2008-09-01 |
| PL1971338T3 (pl) | 2011-07-29 |
| IL191796A0 (en) | 2008-12-29 |
| EP1971338A2 (en) | 2008-09-24 |
| HK1123186A1 (en) | 2009-06-12 |
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