CU20190030A7 - Composiciones de vacunas antineumocócicas polivalentes que comprenden conjugados de polisacárido-proteína - Google Patents
Composiciones de vacunas antineumocócicas polivalentes que comprenden conjugados de polisacárido-proteínaInfo
- Publication number
- CU20190030A7 CU20190030A7 CU2019000030A CU20190030A CU20190030A7 CU 20190030 A7 CU20190030 A7 CU 20190030A7 CU 2019000030 A CU2019000030 A CU 2019000030A CU 20190030 A CU20190030 A CU 20190030A CU 20190030 A7 CU20190030 A7 CU 20190030A7
- Authority
- CU
- Cuba
- Prior art keywords
- polyvalent
- pneumococcal
- antineumococcal
- compositions
- vaccine compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 2
- 150000004676 glycans Chemical class 0.000 abstract 2
- 229940124733 pneumococcal vaccine Drugs 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229940124959 polyvalent pneumococcal vaccine Drugs 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
<p>La presente divulgación se refiere a composiciones de vacunas antineumocócicas polivalentes que comprenden serotipos de polisacáridos neumocócicos capsulares, cada uno conjugado individualmente con proteínas portadoras. AI conjugarse, Ia combinación del serotipo de polisacárido capsular neumocócico y Ia proteína portadora se denomina en Ia presente un conjugado de polisacárido-proteína. Las composiciones de vacunas antineumocócicas pueden comprender además uno o más de los siguientes: un portador aceptable desde el punto de vista farmacéutico, un diluyente aceptable desde el punto de vista farmacéutico, un amortiguador, un conservante, un estabilizante, un adyuvante y/o un excipiente de liofilización. También se proporcionan métodos para preparar y administrar las composiciones de vacunas antineumocócicas descritas en Ia presente.</p>
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201641033563 | 2016-09-30 | ||
PCT/US2017/054237 WO2018064444A1 (en) | 2016-09-30 | 2017-09-29 | Multivalent pneumococcal vaccine compositions comprising polysaccharide-protein conjugates |
Publications (2)
Publication Number | Publication Date |
---|---|
CU20190030A7 true CU20190030A7 (es) | 2019-11-04 |
CU24660B1 CU24660B1 (es) | 2023-05-11 |
Family
ID=60117775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU2019000030A CU24660B1 (es) | 2016-09-30 | 2017-09-29 | Composiciones de vacunas multivalentes que comprenden conjugados de polisacárido-proteína de streptococcus pneumoniae utilizando proteínas portadoras psaa y crm197 |
Country Status (20)
Country | Link |
---|---|
US (1) | US11547752B2 (es) |
EP (1) | EP3518965A1 (es) |
JP (2) | JP2019529497A (es) |
KR (1) | KR102608081B1 (es) |
CN (1) | CN109789198B (es) |
AU (1) | AU2017336806B2 (es) |
BR (1) | BR112019006278A2 (es) |
CA (1) | CA3037056A1 (es) |
CL (1) | CL2019000849A1 (es) |
CO (1) | CO2019002955A2 (es) |
CU (1) | CU24660B1 (es) |
EA (1) | EA201990838A1 (es) |
IL (2) | IL265623B2 (es) |
MX (1) | MX2019003593A (es) |
NZ (1) | NZ752348A (es) |
PH (1) | PH12019500672A1 (es) |
SA (1) | SA519401317B1 (es) |
UA (1) | UA126385C2 (es) |
WO (1) | WO2018064444A1 (es) |
ZA (1) | ZA201901170B (es) |
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MX2019007910A (es) | 2016-12-30 | 2019-12-05 | Sutrovax Inc | Conjugados de polipeptido-antigeno con aminoacidos no naturales. |
US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
GB201711635D0 (en) * | 2017-07-19 | 2017-08-30 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
AU2018400751B2 (en) | 2017-12-06 | 2022-07-21 | Merck Sharp & Dohme Llc | Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
KR102486891B1 (ko) * | 2018-02-05 | 2023-01-10 | 사노피 파스퇴르 인코포레이티드 | 다가 폐렴구균성 다당류-단백질 접합체 조성물 |
IL276229B2 (en) * | 2018-02-05 | 2024-01-01 | Sanofi Pasteur Inc | A multivalent pneumococcal protein-polysaccharide conjugate preparation |
KR20190121713A (ko) | 2018-04-18 | 2019-10-28 | 에스케이바이오사이언스(주) | 스트렙토코커스 뉴모니애 협막 다당류 및 그의 면역원성 접합체 |
WO2020010000A1 (en) * | 2018-07-04 | 2020-01-09 | Sutrovax, Inc. | Improved methods for the preparation of immunogenic conjugates |
EP3817775B1 (en) * | 2018-07-04 | 2024-09-04 | Vaxcyte, Inc. | Improvements in immunogenic conjugates |
JP7337145B2 (ja) * | 2018-07-21 | 2023-09-01 | バイオロジカル イー リミテッド | 保存剤系を含むワクチン製剤 |
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EP3863667A4 (en) * | 2018-10-12 | 2022-08-17 | Biological E Limited | POLYVALENT PNEUMOCOCCAL POLYSACCHARIDE PROTEIN CONJUGATE VACCINE |
AU2019401535B2 (en) * | 2018-12-19 | 2023-12-14 | Merck Sharp & Dohme Llc | Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
WO2020152706A1 (en) * | 2019-01-21 | 2020-07-30 | Biological E Limited | Multivalent pneumococcal conjugate vaccine compositions |
WO2020157772A1 (en) * | 2019-01-28 | 2020-08-06 | Biological E Limited | Multivalent pneumococcal polysaccharide-protein conjugate vaccine compositions |
CN109771640A (zh) * | 2019-02-28 | 2019-05-21 | 北京智飞绿竹生物制药有限公司 | 多价肺炎球菌结合疫苗 |
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AU2020289048A1 (en) * | 2019-06-05 | 2021-12-09 | Merck Sharp & Dohme Llc | Methods of treating patients with an immunogenic composition that protects against |
CN110302375A (zh) * | 2019-06-27 | 2019-10-08 | 康希诺生物股份公司 | 一种糖缀合物及其用途 |
TW202116352A (zh) * | 2019-07-18 | 2021-05-01 | 南韓商賽特瑞恩股份有限公司 | 包含多價肺炎球菌多醣-蛋白共軛物的免疫組成物、醫藥組成物及其用途 |
CN114728050A (zh) * | 2019-07-31 | 2022-07-08 | 圣诺菲·帕斯图尔公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物及其使用方法 |
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US20240181028A1 (en) * | 2022-11-22 | 2024-06-06 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
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2017
- 2017-09-29 WO PCT/US2017/054237 patent/WO2018064444A1/en active Application Filing
- 2017-09-29 KR KR1020197012456A patent/KR102608081B1/ko active IP Right Grant
- 2017-09-29 CN CN201780060834.3A patent/CN109789198B/zh active Active
- 2017-09-29 NZ NZ752348A patent/NZ752348A/en unknown
- 2017-09-29 EP EP17784755.5A patent/EP3518965A1/en active Pending
- 2017-09-29 JP JP2019517383A patent/JP2019529497A/ja not_active Withdrawn
- 2017-09-29 UA UAA201904547A patent/UA126385C2/uk unknown
- 2017-09-29 BR BR112019006278A patent/BR112019006278A2/pt unknown
- 2017-09-29 MX MX2019003593A patent/MX2019003593A/es unknown
- 2017-09-29 AU AU2017336806A patent/AU2017336806B2/en active Active
- 2017-09-29 CU CU2019000030A patent/CU24660B1/es unknown
- 2017-09-29 IL IL265623A patent/IL265623B2/en unknown
- 2017-09-29 CA CA3037056A patent/CA3037056A1/en active Pending
- 2017-09-29 EA EA201990838A patent/EA201990838A1/ru unknown
- 2017-09-29 IL IL297575A patent/IL297575B2/en unknown
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2019
- 2019-02-25 ZA ZA2019/01170A patent/ZA201901170B/en unknown
- 2019-03-14 SA SA519401317A patent/SA519401317B1/ar unknown
- 2019-03-27 CO CONC2019/0002955A patent/CO2019002955A2/es unknown
- 2019-03-28 PH PH12019500672A patent/PH12019500672A1/en unknown
- 2019-03-29 CL CL2019000849A patent/CL2019000849A1/es unknown
- 2019-03-29 US US16/369,933 patent/US11547752B2/en active Active
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2022
- 2022-05-02 JP JP2022076109A patent/JP7403576B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
CL2019000849A1 (es) | 2019-09-23 |
IL265623A (en) | 2019-05-30 |
IL265623B2 (en) | 2023-04-01 |
SA519401317B1 (ar) | 2023-11-14 |
EA201990838A1 (ru) | 2019-08-30 |
BR112019006278A2 (pt) | 2019-07-02 |
AU2017336806A1 (en) | 2019-05-02 |
IL297575B1 (en) | 2023-08-01 |
CU24660B1 (es) | 2023-05-11 |
WO2018064444A1 (en) | 2018-04-05 |
UA126385C2 (uk) | 2022-09-28 |
PH12019500672A1 (en) | 2019-07-29 |
JP2022105155A (ja) | 2022-07-12 |
CA3037056A1 (en) | 2018-04-05 |
ZA201901170B (en) | 2024-08-28 |
IL265623B (en) | 2022-12-01 |
MX2019003593A (es) | 2019-06-10 |
US20190224295A1 (en) | 2019-07-25 |
JP2019529497A (ja) | 2019-10-17 |
CN109789198B (zh) | 2024-08-16 |
KR102608081B1 (ko) | 2023-11-29 |
AU2017336806B2 (en) | 2024-06-27 |
NZ752348A (en) | 2022-11-25 |
JP7403576B2 (ja) | 2023-12-22 |
AU2017336806A8 (en) | 2019-05-16 |
CO2019002955A2 (es) | 2019-06-11 |
IL297575B2 (en) | 2023-12-01 |
CN109789198A (zh) | 2019-05-21 |
KR20190066032A (ko) | 2019-06-12 |
IL297575A (en) | 2022-12-01 |
US11547752B2 (en) | 2023-01-10 |
EP3518965A1 (en) | 2019-08-07 |
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