MX2019003593A - Composiciones de vacuna neumococica multivalente que comprenden conjugados de polisacaridos y proteinas. - Google Patents
Composiciones de vacuna neumococica multivalente que comprenden conjugados de polisacaridos y proteinas.Info
- Publication number
- MX2019003593A MX2019003593A MX2019003593A MX2019003593A MX2019003593A MX 2019003593 A MX2019003593 A MX 2019003593A MX 2019003593 A MX2019003593 A MX 2019003593A MX 2019003593 A MX2019003593 A MX 2019003593A MX 2019003593 A MX2019003593 A MX 2019003593A
- Authority
- MX
- Mexico
- Prior art keywords
- vaccine compositions
- polysaccharide
- pneumococcal vaccine
- pneumococcal
- protein conjugates
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 229940124733 pneumococcal vaccine Drugs 0.000 title abstract 4
- 102000014914 Carrier Proteins Human genes 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 2
- 150000004676 glycans Chemical class 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente descripción se relaciona a composiciones de vacuna neumocócica multivalentes que comprenden los serotipos de polisacáridos neumocócicos capsulares cada uno individualmente conjugado con proteínas portadoras. Cuando se conjuga, la combinación del serotipo de polisacárido neumocócico capsular y la proteína portadora es referida en la 5 presente como un conjugado de polisacárido y proteína. Las composiciones de vacunas neumocócicas pueden además comprender uno o más de los siguientes; un portador farmacéuticamente aceptable, un diluyente farmacéuticamente aceptable, una solución amortiguadora, un conservador, un estabilizador, un adyuvante, y/o un excipiente de liofilización. También se proporcionan los métodos de fabricación y administración de las 10 composiciones de vacunas neumocócicas descritas en la presente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201641033563 | 2016-09-30 | ||
PCT/US2017/054237 WO2018064444A1 (en) | 2016-09-30 | 2017-09-29 | Multivalent pneumococcal vaccine compositions comprising polysaccharide-protein conjugates |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019003593A true MX2019003593A (es) | 2019-06-10 |
Family
ID=60117775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019003593A MX2019003593A (es) | 2016-09-30 | 2017-09-29 | Composiciones de vacuna neumococica multivalente que comprenden conjugados de polisacaridos y proteinas. |
Country Status (20)
Country | Link |
---|---|
US (1) | US11547752B2 (es) |
EP (1) | EP3518965A1 (es) |
JP (2) | JP2019529497A (es) |
KR (1) | KR102608081B1 (es) |
CN (1) | CN109789198B (es) |
AU (1) | AU2017336806B2 (es) |
BR (1) | BR112019006278A2 (es) |
CA (1) | CA3037056A1 (es) |
CL (1) | CL2019000849A1 (es) |
CO (1) | CO2019002955A2 (es) |
CU (1) | CU24660B1 (es) |
EA (1) | EA201990838A1 (es) |
IL (2) | IL265623B2 (es) |
MX (1) | MX2019003593A (es) |
NZ (1) | NZ752348A (es) |
PH (1) | PH12019500672A1 (es) |
SA (1) | SA519401317B1 (es) |
UA (1) | UA126385C2 (es) |
WO (1) | WO2018064444A1 (es) |
ZA (1) | ZA201901170B (es) |
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JP7164200B2 (ja) * | 2016-03-31 | 2022-11-01 | ポゴナ, エルエルシー | サッカライド-ポリペプチドコンジュゲートの組成物およびその使用の方法 |
MX2019007910A (es) | 2016-12-30 | 2019-12-05 | Sutrovax Inc | Conjugados de polipeptido-antigeno con aminoacidos no naturales. |
US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
GB201711635D0 (en) * | 2017-07-19 | 2017-08-30 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
AU2018400751B2 (en) | 2017-12-06 | 2022-07-21 | Merck Sharp & Dohme Llc | Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
KR102486891B1 (ko) * | 2018-02-05 | 2023-01-10 | 사노피 파스퇴르 인코포레이티드 | 다가 폐렴구균성 다당류-단백질 접합체 조성물 |
IL276229B2 (en) * | 2018-02-05 | 2024-01-01 | Sanofi Pasteur Inc | A multivalent pneumococcal protein-polysaccharide conjugate preparation |
KR20190121713A (ko) | 2018-04-18 | 2019-10-28 | 에스케이바이오사이언스(주) | 스트렙토코커스 뉴모니애 협막 다당류 및 그의 면역원성 접합체 |
WO2020010000A1 (en) * | 2018-07-04 | 2020-01-09 | Sutrovax, Inc. | Improved methods for the preparation of immunogenic conjugates |
EP3817775B1 (en) * | 2018-07-04 | 2024-09-04 | Vaxcyte, Inc. | Improvements in immunogenic conjugates |
JP7337145B2 (ja) * | 2018-07-21 | 2023-09-01 | バイオロジカル イー リミテッド | 保存剤系を含むワクチン製剤 |
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AU2019401535B2 (en) * | 2018-12-19 | 2023-12-14 | Merck Sharp & Dohme Llc | Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
WO2020152706A1 (en) * | 2019-01-21 | 2020-07-30 | Biological E Limited | Multivalent pneumococcal conjugate vaccine compositions |
WO2020157772A1 (en) * | 2019-01-28 | 2020-08-06 | Biological E Limited | Multivalent pneumococcal polysaccharide-protein conjugate vaccine compositions |
CN109771640A (zh) * | 2019-02-28 | 2019-05-21 | 北京智飞绿竹生物制药有限公司 | 多价肺炎球菌结合疫苗 |
EP3980055A4 (en) * | 2019-06-05 | 2023-07-26 | Merck Sharp & Dohme LLC | IMMUNOGENIC PNEUMOCOCCUS POLYSACCHARID-PROTEIN CONJUGATE OF SEROTYPE 35B AND CONJUGATION METHODS FOR ITS PRODUCTION |
AU2020289048A1 (en) * | 2019-06-05 | 2021-12-09 | Merck Sharp & Dohme Llc | Methods of treating patients with an immunogenic composition that protects against |
CN110302375A (zh) * | 2019-06-27 | 2019-10-08 | 康希诺生物股份公司 | 一种糖缀合物及其用途 |
TW202116352A (zh) * | 2019-07-18 | 2021-05-01 | 南韓商賽特瑞恩股份有限公司 | 包含多價肺炎球菌多醣-蛋白共軛物的免疫組成物、醫藥組成物及其用途 |
CN114728050A (zh) * | 2019-07-31 | 2022-07-08 | 圣诺菲·帕斯图尔公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物及其使用方法 |
CN110804097B (zh) * | 2019-10-30 | 2021-02-26 | 云南沃森生物技术股份有限公司 | 一种同时制备两种单克隆抗体的方法 |
US20210220461A1 (en) * | 2020-01-17 | 2021-07-22 | Inventprise, Llc | Multivalent Streptococcus Vaccines |
US12053515B2 (en) | 2020-08-10 | 2024-08-06 | Inventprise, Inc. | Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24F |
KR20220102871A (ko) * | 2021-01-14 | 2022-07-21 | (주)셀트리온 | 다가 폐렴구균 다당류-단백질 접합체를 포함하는 면역원성 조성물 |
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US20240181028A1 (en) * | 2022-11-22 | 2024-06-06 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
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2017
- 2017-09-29 WO PCT/US2017/054237 patent/WO2018064444A1/en active Application Filing
- 2017-09-29 KR KR1020197012456A patent/KR102608081B1/ko active IP Right Grant
- 2017-09-29 CN CN201780060834.3A patent/CN109789198B/zh active Active
- 2017-09-29 NZ NZ752348A patent/NZ752348A/en unknown
- 2017-09-29 EP EP17784755.5A patent/EP3518965A1/en active Pending
- 2017-09-29 JP JP2019517383A patent/JP2019529497A/ja not_active Withdrawn
- 2017-09-29 UA UAA201904547A patent/UA126385C2/uk unknown
- 2017-09-29 BR BR112019006278A patent/BR112019006278A2/pt unknown
- 2017-09-29 MX MX2019003593A patent/MX2019003593A/es unknown
- 2017-09-29 AU AU2017336806A patent/AU2017336806B2/en active Active
- 2017-09-29 CU CU2019000030A patent/CU24660B1/es unknown
- 2017-09-29 IL IL265623A patent/IL265623B2/en unknown
- 2017-09-29 CA CA3037056A patent/CA3037056A1/en active Pending
- 2017-09-29 EA EA201990838A patent/EA201990838A1/ru unknown
- 2017-09-29 IL IL297575A patent/IL297575B2/en unknown
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2019
- 2019-02-25 ZA ZA2019/01170A patent/ZA201901170B/en unknown
- 2019-03-14 SA SA519401317A patent/SA519401317B1/ar unknown
- 2019-03-27 CO CONC2019/0002955A patent/CO2019002955A2/es unknown
- 2019-03-28 PH PH12019500672A patent/PH12019500672A1/en unknown
- 2019-03-29 CL CL2019000849A patent/CL2019000849A1/es unknown
- 2019-03-29 US US16/369,933 patent/US11547752B2/en active Active
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2022
- 2022-05-02 JP JP2022076109A patent/JP7403576B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
CL2019000849A1 (es) | 2019-09-23 |
IL265623A (en) | 2019-05-30 |
IL265623B2 (en) | 2023-04-01 |
SA519401317B1 (ar) | 2023-11-14 |
EA201990838A1 (ru) | 2019-08-30 |
BR112019006278A2 (pt) | 2019-07-02 |
AU2017336806A1 (en) | 2019-05-02 |
IL297575B1 (en) | 2023-08-01 |
CU24660B1 (es) | 2023-05-11 |
WO2018064444A1 (en) | 2018-04-05 |
UA126385C2 (uk) | 2022-09-28 |
PH12019500672A1 (en) | 2019-07-29 |
CU20190030A7 (es) | 2019-11-04 |
JP2022105155A (ja) | 2022-07-12 |
CA3037056A1 (en) | 2018-04-05 |
ZA201901170B (en) | 2024-08-28 |
IL265623B (en) | 2022-12-01 |
US20190224295A1 (en) | 2019-07-25 |
JP2019529497A (ja) | 2019-10-17 |
CN109789198B (zh) | 2024-08-16 |
KR102608081B1 (ko) | 2023-11-29 |
AU2017336806B2 (en) | 2024-06-27 |
NZ752348A (en) | 2022-11-25 |
JP7403576B2 (ja) | 2023-12-22 |
AU2017336806A8 (en) | 2019-05-16 |
CO2019002955A2 (es) | 2019-06-11 |
IL297575B2 (en) | 2023-12-01 |
CN109789198A (zh) | 2019-05-21 |
KR20190066032A (ko) | 2019-06-12 |
IL297575A (en) | 2022-12-01 |
US11547752B2 (en) | 2023-01-10 |
EP3518965A1 (en) | 2019-08-07 |
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