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CS182792B2 - Method of production of 2,6-diaminodihydropyridines - Google Patents

Method of production of 2,6-diaminodihydropyridines

Info

Publication number
CS182792B2
CS182792B2 CS7500003602A CS360275A CS182792B2 CS 182792 B2 CS182792 B2 CS 182792B2 CS 7500003602 A CS7500003602 A CS 7500003602A CS 360275 A CS360275 A CS 360275A CS 182792 B2 CS182792 B2 CS 182792B2
Authority
CS
Czechoslovakia
Prior art keywords
diaminodihydropyridines
production
Prior art date
Application number
CS7500003602A
Other languages
Czech (cs)
Inventor
Horst Meyer
Friedrich Bossert
Kurt Stoepel
Wulf Vater
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CS182792B2 publication Critical patent/CS182792B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
CS7500003602A 1972-03-06 1973-03-06 Method of production of 2,6-diaminodihydropyridines CS182792B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2210687A DE2210687C3 (en) 1972-03-06 1972-03-06 2,6-diamino-3,5-diethoxycarbonyldihydropyridines, process for their preparation and pharmaceuticals containing them

Publications (1)

Publication Number Publication Date
CS182792B2 true CS182792B2 (en) 1978-05-31

Family

ID=5838037

Family Applications (2)

Application Number Title Priority Date Filing Date
CS7300001593A CS182781B2 (en) 1972-03-06 1973-03-06 Method of producing 2,6-diaminodihydropyridines
CS7500003602A CS182792B2 (en) 1972-03-06 1973-03-06 Method of production of 2,6-diaminodihydropyridines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS7300001593A CS182781B2 (en) 1972-03-06 1973-03-06 Method of producing 2,6-diaminodihydropyridines

Country Status (24)

Country Link
JP (2) JPS5626659B2 (en)
KR (1) KR780000119B1 (en)
AT (3) AT327904B (en)
BE (1) BE796279A (en)
BG (2) BG20583A3 (en)
CA (1) CA988524A (en)
CH (2) CH580589A5 (en)
CS (2) CS182781B2 (en)
DD (1) DD106833A5 (en)
DE (1) DE2210687C3 (en)
DK (1) DK136061C (en)
ES (1) ES412323A1 (en)
FI (1) FI55996C (en)
FR (1) FR2181789B1 (en)
GB (1) GB1379005A (en)
HU (1) HU167089B (en)
IE (1) IE37370B1 (en)
IL (1) IL41664A (en)
LU (1) LU67147A1 (en)
NL (1) NL7303137A (en)
PL (2) PL92078B1 (en)
RO (2) RO61192A (en)
SE (1) SE384208B (en)
ZA (1) ZA731501B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210687C3 (en) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2,6-diamino-3,5-diethoxycarbonyldihydropyridines, process for their preparation and pharmaceuticals containing them
DE2406198C2 (en) * 1974-02-09 1983-12-15 Bayer Ag, 5090 Leverkusen Process for the preparation of new 2-amino-6-dialkylamino-dihydropyridines
JPS5922593U (en) * 1982-08-03 1984-02-10 日本マランツ株式会社 Horn mounting structure for headphone
JPS5922594U (en) * 1982-08-03 1984-02-10 日本マランツ株式会社 earplug type headphone
JPS6282898A (en) * 1985-10-08 1987-04-16 Matsushita Electric Ind Co Ltd Headphone
JPS6293060U (en) * 1985-11-28 1987-06-13

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3855231A (en) * 1972-03-06 1974-12-17 Bayer Ag 2,6-diamino-1,4-dihydropyridine derivatives
DE2210687C3 (en) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2,6-diamino-3,5-diethoxycarbonyldihydropyridines, process for their preparation and pharmaceuticals containing them
DE2406198C2 (en) * 1974-02-09 1983-12-15 Bayer Ag, 5090 Leverkusen Process for the preparation of new 2-amino-6-dialkylamino-dihydropyridines

Also Published As

Publication number Publication date
DK136061B (en) 1977-08-08
CS182781B2 (en) 1978-05-31
LU67147A1 (en) 1973-05-22
HU167089B (en) 1975-08-28
SE384208B (en) 1976-04-26
FR2181789B1 (en) 1976-12-03
DE2210687A1 (en) 1973-09-20
KR780000119B1 (en) 1978-04-15
ATA925774A (en) 1975-05-15
RO63068A (en) 1978-05-15
BG20583A3 (en) 1975-12-05
DD106833A5 (en) 1974-07-05
BE796279A (en) 1973-09-05
JPS5699460A (en) 1981-08-10
PL89256B1 (en) 1976-11-30
BG22815A3 (en) 1977-04-20
IL41664A0 (en) 1973-05-31
FI55996B (en) 1979-07-31
FI55996C (en) 1979-11-12
RO61192A (en) 1976-09-15
AT327904B (en) 1976-02-25
PL92078B1 (en) 1977-03-31
DE2210687C3 (en) 1981-09-24
DK136061C (en) 1978-01-02
JPS5911584B2 (en) 1984-03-16
CH577473A5 (en) 1976-07-15
FR2181789A1 (en) 1973-12-07
ZA731501B (en) 1973-11-28
CH580589A5 (en) 1976-10-15
DE2210687B2 (en) 1980-09-04
GB1379005A (en) 1975-01-02
NL7303137A (en) 1973-09-10
JPS48103579A (en) 1973-12-25
CA988524A (en) 1976-05-04
AT324338B (en) 1975-08-25
JPS5626659B2 (en) 1981-06-19
IE37370B1 (en) 1977-07-06
IL41664A (en) 1976-01-30
IE37370L (en) 1973-09-06
ES412323A1 (en) 1976-01-01

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