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CR8468A - Derivado de n-(1,5-difenil-1h-pirazol-3-il)metil)sulfonamida con afinidad por los receptores cb1 - Google Patents

Derivado de n-(1,5-difenil-1h-pirazol-3-il)metil)sulfonamida con afinidad por los receptores cb1

Info

Publication number
CR8468A
CR8468A CR8468A CR8468A CR8468A CR 8468 A CR8468 A CR 8468A CR 8468 A CR8468 A CR 8468A CR 8468 A CR8468 A CR 8468A CR 8468 A CR8468 A CR 8468A
Authority
CR
Costa Rica
Prior art keywords
alkyl
unsubstituted
substituted
difenil
pirazol
Prior art date
Application number
CR8468A
Other languages
English (en)
Inventor
Barth Francis
Congy Christian
Martinez Serge
Rinaldi-Carmona Murielle
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of CR8468A publication Critical patent/CR8468A/es

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    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Immunology (AREA)
  • Diabetes (AREA)
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  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Addiction (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
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Abstract

La presente invencion tiene por objeto los compuestos que responden a la formula (I):procedimiento de preparacion y aplicacion en terapeutica en la que R1 representa alquilo(C1-C6) cicloalquilo(C3-C7) no sustituido o sustituido una o varias veces, cicloalquilmetilo(C3-C7)no sustituido o sustituido una o varias veces, fenilo no sustituido o sustituido, bencilo no sustituido o mono o disustituido, tienilo no sustituido o sustituido, R2 representa un atomo de hidrogeno o alquilo (C1-C3), R3 representa un atomo de hidrogeno o alquilo (C1-C5),R4, R5,R6,R7,R8 y R9 representan cada uno de manera independiente un atomo de halogeno, alquilo (C1-C7), alcoxi(C1-C5), radical trifluorometilo o grupo S(O)nAlk; n representa 0, 1 o 2; Alk representa alquilo(C1-C4). Procedimiento de preparacion y aplicacion en terapeutica.
CR8468A 2004-01-12 2006-06-21 Derivado de n-(1,5-difenil-1h-pirazol-3-il)metil)sulfonamida con afinidad por los receptores cb1 CR8468A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0400257A FR2864958B1 (fr) 2004-01-12 2004-01-12 Derive de n-[(1,5-diphenyl-1h-pyrazol-3-yl)methyl] sulfonamide, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
CR8468A true CR8468A (es) 2007-03-06

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CR8468A CR8468A (es) 2004-01-12 2006-06-21 Derivado de n-(1,5-difenil-1h-pirazol-3-il)metil)sulfonamida con afinidad por los receptores cb1

Country Status (31)

Country Link
US (1) US7294645B2 (es)
EP (1) EP1720837B1 (es)
JP (1) JP4723514B2 (es)
KR (1) KR20060105050A (es)
CN (1) CN1910157A (es)
AR (1) AR047096A1 (es)
AT (1) ATE465995T1 (es)
AU (1) AU2005209441B2 (es)
CA (1) CA2551141C (es)
CR (1) CR8468A (es)
CY (1) CY1110651T1 (es)
DE (1) DE602005020907D1 (es)
DK (1) DK1720837T3 (es)
EC (1) ECSP066695A (es)
ES (1) ES2344850T3 (es)
FR (1) FR2864958B1 (es)
HR (1) HRP20100283T8 (es)
IL (1) IL176710A0 (es)
MA (1) MA28422B1 (es)
NO (1) NO20063621L (es)
NZ (1) NZ548442A (es)
PL (1) PL1720837T3 (es)
PT (1) PT1720837E (es)
RS (1) RS51365B (es)
RU (1) RU2366657C2 (es)
SI (1) SI1720837T1 (es)
TN (1) TNSN06203A1 (es)
TW (1) TWI323255B (es)
UA (1) UA85079C2 (es)
WO (1) WO2005073197A1 (es)
ZA (1) ZA200605657B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7030141B2 (en) * 2001-11-29 2006-04-18 Christopher Franklin Bigge Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
FR2880023B1 (fr) * 2004-12-23 2007-02-23 Sanofi Aventis Sa Derives de n-[(4,5-diphenyl-3-alkyl-2-thienyl) methyl] amine leur preparation et leur application en therapeutique
FR2880890B1 (fr) * 2005-01-19 2007-03-30 Sanofi Aventis Sa Derives de n-[(4,5-diphenyl-2-thienyl)methyl]sulfonamide, leur preparation et leur application en therapeutique
FR2881744B1 (fr) 2005-02-09 2007-04-27 Sanofi Aventis Sa Derives de n-[(4,5-diphenyl-2-thienyl)methyl]amine, leur preparation et leur application en therapeutique
FR2894579B1 (fr) * 2005-12-12 2008-01-18 Sanofi Aventis Sa Derives diaryltriazolmethylamine, leur preparation et leur application en therapeutique.
FR2894578B1 (fr) * 2005-12-12 2008-02-01 Sanofi Aventis Sa Derives heterocycliques, leur preparation et leur application en therapeutique.
EP1829867A1 (en) 2006-03-03 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Imidazole compounds having pharmaceutical activity towards the sigma receptor
FR2899899A1 (fr) * 2006-04-14 2007-10-19 Sanofi Aventis Sa Derives d'aminomethyl pyridine, leur preparation et leur application en therapeutique
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JP2007517839A (ja) 2007-07-05
US20070021486A1 (en) 2007-01-25
EP1720837A1 (fr) 2006-11-15
AU2005209441B2 (en) 2010-12-23
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US7294645B2 (en) 2007-11-13
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ATE465995T1 (de) 2010-05-15
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CA2551141C (fr) 2011-06-07
DE602005020907D1 (de) 2010-06-10
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FR2864958B1 (fr) 2006-02-24
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RU2006129297A (ru) 2008-02-20
SI1720837T1 (sl) 2010-08-31
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