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CO6300826A2 - Metodos y composiciones que utilizan polipeptidos de fusion de klotho-fgf - Google Patents

Metodos y composiciones que utilizan polipeptidos de fusion de klotho-fgf

Info

Publication number
CO6300826A2
CO6300826A2 CO10092102A CO10092102A CO6300826A2 CO 6300826 A2 CO6300826 A2 CO 6300826A2 CO 10092102 A CO10092102 A CO 10092102A CO 10092102 A CO10092102 A CO 10092102A CO 6300826 A2 CO6300826 A2 CO 6300826A2
Authority
CO
Colombia
Prior art keywords
klotho
compositions
methods
fusion polypeptides
fgf fusion
Prior art date
Application number
CO10092102A
Other languages
English (en)
Inventor
David Jonathan Glass
Shoo-Ih Hu
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CO6300826A2 publication Critical patent/CO6300826A2/es

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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P13/00—Drugs for disorders of the urinary system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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Abstract

La presente invención se refiere a métodos, kits, y composiciones para prevenir o tratar condiciones relacionadas con la edad o trastornos metabólicos. Los polipéptidos de fusión Klotho de la invención incluyen cuando menos una proteína Klotho o un fragmento activo de la misma. Las proteínas de fusión Klotho son útiles en el tratamiento y en la prevención de una variedad de condiciones relacionadas con la edad y trastornos metabólicos.
CO10092102A 2008-01-28 2010-07-28 Metodos y composiciones que utilizan polipeptidos de fusion de klotho-fgf CO6300826A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6301508P 2008-01-28 2008-01-28

Publications (1)

Publication Number Publication Date
CO6300826A2 true CO6300826A2 (es) 2011-07-21

Family

ID=40492768

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CO10092102A CO6300826A2 (es) 2008-01-28 2010-07-28 Metodos y composiciones que utilizan polipeptidos de fusion de klotho-fgf

Country Status (21)

Country Link
US (2) US8481031B2 (es)
EP (1) EP2247614B1 (es)
JP (1) JP5627469B2 (es)
KR (1) KR20100118126A (es)
CN (1) CN102015760B (es)
AR (1) AR070690A1 (es)
AU (1) AU2009209696B2 (es)
BR (1) BRPI0906722A2 (es)
CA (2) CA2712634C (es)
CL (1) CL2009000166A1 (es)
CO (1) CO6300826A2 (es)
CR (1) CR11580A (es)
EA (1) EA201001204A1 (es)
EC (1) ECSP10010372A (es)
ES (1) ES2479417T3 (es)
IL (1) IL207161A0 (es)
MA (1) MA32031B1 (es)
MX (1) MX2010008206A (es)
PE (1) PE20091405A1 (es)
TW (1) TW200936156A (es)
WO (1) WO2009095372A1 (es)

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CR11580A (es) 2010-10-05
AR070690A1 (es) 2010-04-28
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