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CN218496567U - Peripheral blood mixing mechanism, mixing mechanism and sample analyzer - Google Patents

Peripheral blood mixing mechanism, mixing mechanism and sample analyzer Download PDF

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Publication number
CN218496567U
CN218496567U CN202221733884.8U CN202221733884U CN218496567U CN 218496567 U CN218496567 U CN 218496567U CN 202221733884 U CN202221733884 U CN 202221733884U CN 218496567 U CN218496567 U CN 218496567U
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China
Prior art keywords
mixing
peripheral blood
sample
container
blending
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CN202221733884.8U
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Chinese (zh)
Inventor
吴日亮
卢江涛
邓健波
郭俊游
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Shenzhen Reetoo Biotechnology Co Ltd
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Shenzhen Reetoo Biotechnology Co Ltd
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Abstract

The utility model provides a peripheral blood mixing mechanism, a mixing mechanism and a sample analyzer, wherein the peripheral blood mixing mechanism comprises a bearing seat and a mixing driving component; the bearing seat is used for bearing the sample container; the blending driving assembly is connected with the bearing seat and used for driving the bearing seat to move transversely so as to drive the sample container to move transversely to blend the peripheral blood sample in the sample container. This tip blood mixing mechanism, mixing mechanism and sample analysis appearance can satisfy the mixing demand of tip blood well, improve the measurement accuracy.

Description

Peripheral blood mixing mechanism, mixing mechanism and sample analyzer
Technical Field
The utility model relates to a blood sample analysis technical field especially relates to a tip blood mixing mechanism, mixing mechanism and sample analyzer.
Background
Blood sampling requires the collection of a volume of sample from a patient by means including venous blood collection and peripheral blood collection. Peripheral blood is usually collected from patients who are not suitable for venous blood collection, such as neonates, infants, and intensive care patients. The phenomenon of layering can appear after the peripheral blood after collecting is placed for a period of time, and if direct sampling measurement is carried out, the measurement result can generate larger deviation. Because the peripheral blood has less blood sampling amount and poor fluidity, the existing peripheral blood mixing mode has poor mixing effect, thereby influencing the measurement accuracy.
SUMMERY OF THE UTILITY MODEL
The utility model provides a tip blood mixing mechanism, mixing mechanism and sample analyzer to satisfy the mixing demand of tip blood well, improve measuring accuracy.
The utility model provides a tip blood mixing mechanism for tip blood in the mixing sample container, tip blood mixing mechanism includes:
the bearing seat is used for bearing the sample container;
the blending driving assembly is connected with the bearing seat and used for driving the bearing seat to move transversely, so that the sample container is driven to move transversely to blend the peripheral blood sample in the sample container.
The utility model discloses an among the tip blood mixing mechanism, mixing drive assembly is used for driving bear the horizontal reciprocating motion of seat.
The utility model discloses an among the tip blood mixing mechanism, mixing drive assembly is used for driving bear the seat and do curve or straight reciprocating motion.
The utility model discloses an among the tip blood mixing mechanism, mixing drive assembly is used for driving bear the seat and do arc reciprocating motion.
In the peripheral blood mixing mechanism of the present invention, the bearing seat is used for bearing an emergency sample container and/or a conventional sample container.
In the peripheral blood mixing mechanism of the utility model, the mixing driving component is used for driving the bearing seat to move transversely and reciprocally for 300 times/min to 800 times/min.
The utility model discloses an among the tip blood mixing mechanism, mixing drive assembly is used for driving bear the reciprocal sideslip of seat 800 times/min.
The utility model discloses an among the tip blood mixing mechanism, mixing drive assembly includes:
a blending drive member;
and the mixing driving part can drive the mixing driving part to do rotary motion to drive the bearing seat to move transversely.
The utility model discloses an among the tip blood mixing mechanism, the mixing driving medium includes:
the cam is fixedly connected with the blending driving piece and is in transmission connection with the bearing seat.
The utility model discloses an among the tip blood mixing mechanism, be equipped with the bearing on the bearing seat, the bearing with cam drive connects.
The utility model discloses an among the tip blood mixing mechanism, the mixing driving medium includes:
the crank is connected with the blending driving part;
and one end of the crank connecting rod is connected with the crank, and the other end of the crank connecting rod is connected with the bearing seat.
In the peripheral blood mixing mechanism of the utility model, the peripheral blood mixing mechanism further comprises a mixing support, and the mixing driving component is arranged on the mixing support; the mixing drive assembly further comprises:
the mixing piece that resets, one end with mixing support butt, the other end with bear the seat butt, be used for resetting bear the seat.
The utility model discloses an among the tip blood mixing mechanism, the mixing piece that resets includes the elastic component, the one end of elastic component with mixing support butt, the other end of elastic component with bear the weight of a seat butt.
The utility model discloses an among the tip blood mixing mechanism, tip blood mixing mechanism still includes:
the guide rod is arranged on the blending support and is in sliding fit with the bearing seat.
The utility model discloses an among the tip blood mixing mechanism, be equipped with on the mixing support with bear seat sliding fit's mixing slide rail, mixing drive assembly is used for the drive to bear the seat and follows slide on the mixing slide rail.
The utility model discloses an among the tip blood mixing mechanism, it is used for holding to bear to be equipped with on the seat sample container's holding tank, the diameter of holding tank is greater than sample container's diameter.
The utility model discloses an among the tip blood mixing mechanism, the diameter ratio of holding tank the diameter of sample container is 0.5mm-3mm big.
The utility model discloses an among the tip blood mixing mechanism, it is used for holding to bear to be equipped with on the seat sample container's holding tank, the holding tank adopts the reducing setting, the holding tank one end with the spacing cooperation of sample container, the diameter ratio of the other end of holding tank sample container's diameter is 0.5mm-3mm big.
The utility model discloses an among the tip blood mixing mechanism, be equipped with two holding tanks, every on bearing the seat the holding tank is used for holding one the sample container.
The utility model discloses an among the tip blood mixing mechanism, two one of them in the holding tank is used for the transfer buffer memory the sample container.
The utility model discloses an among the tip blood mixing mechanism, it is used for holding to bear to be equipped with on the seat sample container's holding tank, be equipped with in the holding tank and be used for locating the cell wall of holding tank with damper between the sample container.
The utility model also provides a mixing mechanism for the sample in the mixing sample container, mixing mechanism includes:
a container holder for carrying the sample container;
the bearing seat is connected with the container seat;
the blending driving component is connected with the bearing seat and is used for driving the bearing seat to transversely move;
a locking assembly in a locked state when the sample container is of the type of a peripheral blood container, the locking assembly locking the receptacle to limit lateral oscillation of the receptacle relative to the carrier; when the sample container is a venous blood container, the locking assembly is in an unlocked state, and the locking assembly unlocks the container holder so that the container holder can swing transversely relative to the carrier holder.
The utility model discloses an among the mixing mechanism, be equipped with two gag lever posts on the bearing seat, be used for the restriction the swing angle of container seat is no longer than 180 degrees.
The utility model discloses an among the mixing mechanism, mixing mechanism still includes:
and the container type detection device is arranged on the bearing seat and is used for detecting the type of the sample container, and the type of the sample container comprises a peripheral blood container and a venous blood container.
The utility model discloses an among the mixing mechanism, container type detection device includes at least one among capacitive sensor, opto-coupler sensor, inductive transducer, the pressure sensor.
The utility model discloses an among the mixing mechanism, the locking subassembly includes: the container comprises an electromagnet and an iron sheet matched with the electromagnet, wherein one of the electromagnet and the iron sheet is arranged on the bearing seat, the other one of the electromagnet and the iron sheet is arranged on the container seat, and the position of the electromagnet corresponds to the position of the iron sheet.
The utility model also provides a sample analyzer, include:
the peripheral blood mixing mechanism according to any one of the above or the mixing mechanism according to any one of the above;
the sampling mechanism is used for collecting the uniformly mixed sample in the sample container; and
a reaction measurement mechanism to which the sampling mechanism injects the collected sample.
The utility model provides a tip blood mixing mechanism, mixing mechanism and sample analysis appearance drives through mixing drive assembly and bears seat lateral shifting to drive sample container lateral shifting and carry out the mixing with the tip blood sample to in the sample container. The mixing mode can ensure that the sample is kept at the bottom of the sample container as much as possible in the mixing process and well meets the requirement of sample mixing, particularly the mixing requirement of trace peripheral blood can be well met, and the measurement accuracy is improved; and the reciprocating transverse movement of the sample container can reduce the liquid-hanging residual quantity of the sample on the inner wall of the sample container in order to realize the uniform mixing, thereby reducing the loss of the sample and reducing or avoiding the problem that the sample overflows from the sample container due to the climbing of the liquid surface.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the disclosure of embodiments of the invention.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without any creative effort.
Fig. 1 (a) is a schematic structural diagram of a sample analyzer provided in an embodiment of the present invention;
fig. 1 (B) is a schematic partial structural diagram of a sample analyzer provided in an embodiment of the present invention;
fig. 2 (a) is a schematic structural diagram of a tip blending mechanism according to an embodiment of the present invention;
fig. 2 (B) is a cross-sectional view of a tip blending mechanism according to an embodiment of the present invention;
fig. 2 (C) is a schematic structural diagram of a tip blending mechanism according to an embodiment of the present invention;
fig. 2 (D) is a schematic structural diagram of a blending mechanism provided in the embodiment of the present invention;
fig. 2 (E) is a schematic structural diagram of a load-bearing seat according to an embodiment of the present invention.
Description of reference numerals:
10. a sample introduction mechanism; 20. a moving mechanism;
30. a blending mechanism; 31. a bearing seat; 311. a blending slide block; 312. accommodating grooves; 32. a blending drive assembly; 321. a blending drive; 322. uniformly mixing a transmission part; 3221. a crank; 3222. a crank connecting rod; 323. a bearing; 324. mixing the reset pieces; 33. uniformly mixing the bracket; 331. uniformly mixing a sliding rail; 34. a guide bar; 35. a container base; 36. a locking assembly; 361. an electromagnet; 362. iron sheets;
40. a sampling mechanism; 50. a reaction measurement mechanism.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and to simplify the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention. Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. Thus, features defined as "first" and "second" may explicitly or implicitly include one or more of the described features. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
It is also to be understood that the terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in the specification and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
It should be further understood that the term "and/or" as used in the specification and the appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes such combinations.
The utility model provides a sample analyzer, this sample analyzer are used for the analysis sample. The sample analyzer may include at least one of a blood analyzer, a specific protein analyzer, a hemoglobin analyzer, and the like. The sample may include blood, urine, gynecological secretions, ascites, cerebrospinal fluid, or pleural fluid, among others.
Referring to fig. 1 (a) and 1 (B), the sample analyzer includes a mixing mechanism 30, a sampling mechanism 40, and a reaction measuring mechanism 50. The mixing mechanism 30 is used for mixing the sample in the sample container. The sampling mechanism 40 is used to collect a sample in a sample container. The sampling mechanism 40 injects the collected sample into the reaction measurement mechanism 50. The sampling mechanism 40 is used to collect a sample in a sample container and inject the collected sample into the reaction measuring mechanism 50. The reaction measuring mechanism 50 is used to perform a measuring operation on a sample.
It will be appreciated that certain components of the present embodiment may be omitted or not used for testing of certain specimens. For example, for a sample such as urine, which is not usually mixed before measurement, and therefore does not need to use the mixing mechanism 30, the sampling mechanism 40 may collect the unmixed sample and inject the unmixed sample into the reaction measurement mechanism 50 for measurement, such as five-class leukocyte detection. For samples that do not require blending using the blending mechanism 30, the sample container may be introduced without a container cap.
For samples such as peripheral blood and venous blood, the samples are usually mixed before measurement, and the sampling mechanism 40 can collect the mixed samples and inject the samples into the reaction measurement mechanism 50 for measurement. For samples that need to be blended using the blending mechanism 30, the sample container is typically capped to prevent the sample from overflowing the sample container during blending.
Referring to fig. 1 (a), in some embodiments, the sample analyzer further includes a sample introduction mechanism 10 and a removal mechanism 20. The sample introduction mechanism 10 is used for storing sample containers. The removing mechanism 20 is used for conveying the sample container to the blending mechanism 30 or the sampling mechanism 40.
An embodiment of the utility model provides a mixing mechanism 30 includes tip blood mixing mechanism, and tip blood mixing mechanism is arranged in the tip blood of mixing sample container S. Referring to fig. 2 (a), the peripheral blood mixing mechanism includes a bearing seat 31 and a mixing driving assembly 32. The carrier 31 is used for carrying the sample container S. The blending driving component 32 is connected with the bearing seat 31. The blending driving component 32 is used for driving the bearing seat 31 to move transversely, so as to drive the sample container S to move transversely to blend the peripheral blood sample in the sample container S.
The tip blood mixing mechanism of the embodiment has the advantages of ingenious structural design and strong practicability, and drives the bearing seat 31 to move transversely through the mixing driving component 32, so that the sample container S is driven to move transversely to mix the tip blood sample in the sample container S. The mixing mode can keep the sample at the bottom of the sample container S as much as possible in the mixing process, well meet the requirement of sample mixing, particularly well meet the mixing requirement of trace peripheral blood, and improve the measurement accuracy; and the sample container S is in a reciprocating and transverse movement mode so as to realize uniform mixing, the liquid hanging residual quantity of the sample on the inner wall of the sample container S can be reduced, the sample loss effect is reduced, and the problem that the sample overflows the sample container S due to the fact that the liquid level climbs can be relieved or avoided.
Of course, the peripheral blood mixing mechanism may be used for mixing a sample container S containing a large sample amount. Therefore, the sample container S that can be carried by the carrier 31 may be a peripheral blood container (for example, a micro blood collection tube containing peripheral blood) containing a small amount of peripheral blood, a venous blood container (for example, a vacuum blood collection tube containing venous blood) containing a large amount of venous blood, or a sample container containing urine, ascites, or the like. However, the peripheral blood mixing mechanism of the present embodiment has a significant advantage in a sample container (for example, a micro blood collection tube for peripheral blood) containing a small amount of sample.
Referring to fig. 2 (a), in some embodiments, the kneading drive assembly 32 is used to drive the carrier 31 to move transversely (hereinafter referred to as "reciprocating traverse"). Through the reciprocal sideslip of bearing seat 31, sample container S also follows reciprocal sideslip, can realize better mixing effect from this.
Referring to fig. 2 (a), the blending driving assembly 32 is used to drive the carrying seat 31 to move linearly and reciprocally. So, not only can satisfy the requirement of sample mixing well, the sample in the sample container S need not to do the circular rotation moreover, has reduced the liquid residual amount of hanging of sample on the inner wall of sample container S from this to reduce the effect of sample loss, and prevented because the sample is circular rotation and arouse the liquid level to climb and then lead to the problem that the sample spills over sample container S.
In some embodiments, the blending driving assembly 32 is configured to drive the carrying base 31 to reciprocate in a curve or a straight line.
In some embodiments, the blending driving assembly 32 is configured to drive the carrying base 31 to perform an arc-shaped reciprocating motion. The reciprocating movement of the bearing seat 31 has a simple track, and is convenient to process.
In some embodiments, the sample containers S include emergency sample containers and conventional sample containers. The bearing seat 31 is used for bearing an emergency sample container and/or a conventional sample container so as to realize the blending of emergency samples and the blending of conventional samples. The conventional sample container contains a conventional sample therein. The emergency sample container contains an emergency sample. Illustratively, when an emergency sample is tested, the bearing seat 31 is used for bearing an emergency sample container so that the peripheral blood blending mechanism can blend the emergency sample in the emergency sample container; when testing a regular sample, the holder 31 is used for holding a regular sample container, so that the peripheral blood mixing mechanism can mix the regular sample in the regular sample container. In some application scenarios, the bearing seat 31 can simultaneously bear the emergency sample container and the conventional sample container, so that the peripheral blood blending mechanism can simultaneously blend the emergency sample in the emergency sample container and the conventional sample in the conventional sample container, thereby improving the testing efficiency.
In some embodiments, the blending driving assembly 32 is configured to drive the carrying seat 31 to move transversely for 300 times/min to 800 times/min, such as 300 times/min, 600 times/min, 800 times/min, and any other suitable value between 300 times/min to 800 times/min, so as to achieve a better blending effect and a better realizability. Understandably, if the reciprocating traversing frequency of the bearing seat 31 is too low, the sample mixing effect is not ideal; if the frequency of the reciprocating traverse of the bearing seat 31 is too high, the blending driving assembly 32 needs to work at a relatively high working frequency, which results in a difficult design and is not easy to implement.
Illustratively, the blending driving assembly 32 is used for driving the bearing seat 31 to move transversely and reciprocally 500 times/min-800 times/min. For example, the blending driving assembly 32 is used to drive the carrying seat 31 to move transversely and reciprocally 800 times/min.
In some embodiments, the blending drive assembly 32 includes a blending drive 321 and a blending drive 322. The blending driving member 322 is connected to the blending driving member 321. The blending driving member 322 is connected to the carrying seat 31, and the blending driving member 321 can drive the blending driving member 322 to rotate to drive the carrying seat 31 to move transversely. By designing the blending transmission member 322, the rotational motion of the blending driving assembly 32 can be converted into the lateral movement of the bearing seat 31.
In some embodiments, the blending drive 321 comprises a blending motor or cylinder, or the like. The blending motor can comprise a stepping motor, a direct current motor or a servo motor and the like. Illustratively, the blending motor is a stepper motor.
It will be appreciated that the blending drive 321 may be communicatively coupled to a control element (not shown) of the sample analyzer for controlling the start, shut-off, and rotational speed of the blending drive 321, among other things.
Illustratively, the blending driving member 321 includes a blending motor, and the blending motor can drive the blending driving member 322 to rotate clockwise and/or counterclockwise, so as to drive the bearing seat 31 to move transversely.
Referring to fig. 2 (B), in some embodiments, the blending drive 322 includes a cam. The cam is fixedly connected with the blending driving member 321. The cam is in transmission connection with the bearing seat 31. When the blending driving member 321 drives the cam to make a rotation motion, the bearing seat 31 moves back and forth and transversely along with the shape change of the outer periphery of the cam. The blending driving component 32 with the structure has the advantages of compact and simple structure and high stability.
Referring to fig. 2 (B), in some embodiments, the bearing block 31 is provided with a bearing 323. The bearing 323 is drivingly connected with the cam to reduce friction between the carrier 31 and the cam, so that the carrier 31 can move laterally more smoothly and efficiently.
Referring to fig. 2 (C), in some embodiments, the kneading drive 322 includes a crank 3221 and a crank link 3222. The crank 3221 is connected to the kneading drive member 321. One end of the crank connecting rod 3222 is connected to the crank 3221, and the other end of the crank connecting rod 3222 is connected to the carriage 31. It will be appreciated that the direction of movement of the crank link 3222 is the same as the direction of the reciprocating transverse movement of the carrier 31. The crank 3221 is driven to rotate by the blending driving part 321; the crank connecting rod 3222 moves linearly, thereby achieving the reciprocating transverse movement of the bearing seat 31.
Referring to fig. 2 (a) and 2 (B), in some embodiments, the peripheral blood mixing mechanism further includes a mixing support 33. The kneading drive assembly 32 is provided on the kneading support 33. Illustratively, the kneading drive 321 is fixed to the kneading carriage 33.
Referring to fig. 2 (a) and 2 (B), in some embodiments, the blend drive assembly 32 further includes a blend return 324. One end of the mixing resetting piece 324 is abutted against the mixing bracket 33, and the other end of the mixing resetting piece 324 is abutted against the bearing seat 31 for resetting the bearing seat 31. The blending resetting member 324 can reset the bearing seat 31, and the bearing seat 31 abuts against the blending transmission member 322, so that the bearing seat 31 and the blending transmission member 322 are in reliable transmission fit.
In some embodiments, the blending returning member 324 includes an elastic member, one end of the elastic member abuts against the blending bracket 33, and the other end of the elastic member abuts against the bearing seat 31. Illustratively, the resilient member comprises a spring.
Referring to fig. 2 (a) and 2 (B), in some embodiments, the peripheral blood mixing mechanism further includes a guide rod 34. The guide bar 34 is provided on the kneading bracket 33. The guide bar 34 is slidably engaged with the carrier 31. The guide rod 34 can guide the movement of the bearing seat 31, so that the bearing seat 31 can stably and reliably move transversely, and the structure is simple and easy to realize. Referring to fig. 2 (a), illustratively, a kneading block 311 is disposed on the bearing seat 31, and the kneading block 311 is slidably engaged with the guide rod 34.
Referring to fig. 2 (C) and fig. 2 (D), in some embodiments, the blending rack 33 is provided with a blending slide rail 331 slidably engaged with the bearing seat 31, and the blending driving component 32 is configured to drive the bearing seat 31 to slide along the blending slide rail 331. So, mixing slide rail 331's setting can guarantee to bear the stable and reliable lateral shifting of seat 31, and simple structure easily realizes.
Referring to fig. 2 (C), for example, a blending slider 311 is disposed on the bearing seat 31, and the blending slider 311 is slidably engaged with the blending slide rail 331.
Referring to fig. 2 (a) and 2 (C), it can be understood that the loading base 31 is provided with a receiving groove 312 for receiving the sample container S.
In some embodiments, the diameter of the receiving groove 312 is larger than the diameter of the sample container S. So, when bearing the reciprocal sideslip of seat 31, sample container S follows and bears the reciprocal sideslip of seat 31, and sample container S can collide repeatedly and form the action of strikeing repeatedly with the cell wall of holding tank 312, and simulation medical personnel is with the mixing mode that the finger played the test tube, and the mixing effect is fairly better with the mixing mode that the finger played the test tube for medical personnel, need not medical personnel manual operation simultaneously.
The diameter of the accommodating groove 312 is too large than that of the sample container S, which may cause the sample container S to easily separate from the accommodating groove 312, and it is difficult to stably and reliably hold the sample container S in the accommodating groove 312 for uniform mixing. The diameter of the holding groove 312 is too close to that of the sample container S, and when the carrier 31 moves in a reciprocating manner, the sample container S and the groove wall of the holding groove 312 are difficult to form a reciprocating knocking action, so that the uniform mixing effect is poor. Illustratively, the diameter of the receiving groove 312 is 0.5mm to 3mm larger than the diameter of the sample container S, such as 0.5mm, 1mm, 2mm, 3mm, and any other suitable value from 0.5mm to 3mm.
In some embodiments, the accommodating groove 312 has a variable diameter, one end of the accommodating groove 312 is in limit fit with the sample container S, and the diameter of the other end of the accommodating groove 312 is 0.5mm to 3mm larger than the diameter of the sample container S. So, when bearing the reciprocal sideslip of seat 31, the one end of holding tank 312 can carry on spacingly to sample container S ' S corresponding position, and sample container S ' S the other end is followed and is born the reciprocal sideslip of seat 31, and sample container S ' S the other end can collide repeatedly with the cell wall of holding tank 312 and form the action of strikeing repeatedly, simulates the mixing mode that medical personnel used the finger bullet test tube, and the mixing effect is fairly medical personnel better with the mixing mode that the finger played the test tube, need not medical personnel manual operation simultaneously.
Illustratively, the upper end of the receiving groove 312 is in a positive fit with the sample container S, and the diameter of the lower end of the receiving groove 312 is 0.5mm to 3mm larger than the diameter of the sample container S. Can fully mix a small amount of blood samples in this embodiment, the mixing effect is good.
Illustratively, the lower end of the receiving groove 312 is in a positive fit with the sample container S, and the upper end of the receiving groove 312 has a diameter 0.5mm to 3mm larger than the diameter of the sample container S.
Referring to fig. 2 (E), in some embodiments, two receiving grooves 312 are formed on the supporting base 31. Each accommodating groove 312 is used to accommodate one sample container S. So, can carry out the mixing to the sample in two sample containers S simultaneously, improve mixing efficiency.
In some embodiments, one of the two receiving slots 312 is used to relay the buffered sample container S. Because the path between the peripheral blood blending mechanism and the mechanism (such as the second blending mechanism 302 or the sampling mechanism 40) for subsequent operation is smaller than the path between the sample injection site and the mechanism for subsequent operation, one of the two accommodating grooves 312 is used for transferring the buffered sample container S, and the testing efficiency of the sample analyzer can be improved.
In some embodiments, a shock absorbing member (not shown) is disposed in the receiving groove 312 between a groove wall of the receiving groove 312 and the sample container S to reduce the sound generated when the receiving groove 312 strikes the sample container S when the carriage 31 moves back and forth.
Referring to fig. 2 (D), an embodiment of the present invention further provides a blending mechanism 30 for blending the sample in the sample container S. The kneading mechanism 30 includes a container holder 35, a holder 31, a kneading drive unit 32 (see fig. 2 a), and a lock unit 36. The container holder 35 is used to carry the sample container S. The carrier seat 31 is connected to the receptacle seat 35. The blending driving component 32 is connected with the bearing seat 31. The blending driving assembly 32 is used for driving the bearing seat 31 to move transversely. When the sample container S is of the peripheral blood container type, the locking assembly 36 is in a locked state, and the locking assembly 36 locks the container holder 35 to restrict the container holder 35 from swinging laterally relative to the carrier holder 31. When the type of the sample container S is a venous blood container, the locking assembly 36 is in an unlocked state, and the locking assembly 36 unlocks the container holder 35 so that the container holder 35 can swing laterally relative to the carrier holder 31.
In the blending mechanism 30 in the above embodiment, the locking component 36 can be switched between the locking state and the unlocking state according to the type of the sample container S, so that the blending mechanism 30 can perform blending operation on the sample in the sample container S in a blending manner corresponding to the type of the sample container S, thereby achieving an optimal blending effect. Specifically, when the type of the sample container S is a peripheral blood container, the locking assembly 36 locks the container holder 35 to limit the container holder 35 from swinging transversely relative to the bearing seat 31, in the sample blending process, the container holder 35 is fixed relative to the bearing seat 31, the blending driving assembly 32 drives the bearing seat 31 to move transversely, and the container holder 35 and the sample container S move transversely along with the bearing seat 31, so that the sample blending operation is realized. Therefore, the sample can be kept at the bottom of the sample container S as much as possible in the process of uniformly mixing, the requirement of uniformly mixing the sample can be well met, and particularly the requirement of uniformly mixing trace peripheral blood can be well met; and the sample container S moves transversely in a reciprocating manner to realize the blending operation, so that the hanging liquid residual quantity of the sample on the inner wall of the sample container S is reduced, the sample loss is reduced, and the sample container S has obvious advantages for the sample container S filled with a small amount of sample (such as a micro blood collection tube filled with peripheral blood).
When the type of sample container S is a venous blood container, the locking assembly 36 unlocks the container holder 35 so that the container holder 35 can swing laterally relative to the carrier holder 31. In the sample mixing process, the mixing driving component 32 drives the bearing seat 31 to move transversely, the container seat 35 moves transversely along with the bearing seat 31, and the container seat 35 swings transversely relative to the bearing seat 31, so that the sample container S on the container seat 35 swings transversely while moving transversely, and the sample mixing operation is realized. This blending method has significant advantages for sample containers S containing larger sample volumes (e.g., venous blood containers containing venous blood).
Illustratively, the bearing seat 31 includes the bearing seat 31 of any of the above embodiments. The blend drive assembly 32 includes the blend drive assembly 32 of any of the embodiments described above.
In some embodiments, two stop rods (not shown) are disposed on the carrier 31 for limiting the swing angle of the container holder 35 to not exceed 180 degrees. Therefore, on the premise of realizing the blending requirement, the liquid hanging residual quantity of the sample on the inner wall of the sample container S can be reduced as much as possible, the sample loss effect is reduced, and the problem that the sample overflows the sample container S due to the climbing of the liquid level is relieved as much as possible.
In some embodiments, the blending mechanism 30 further comprises a container type detection device (not shown) for detecting the type of the sample container S. The container type detecting means is provided on the carrier base 31, and the types of the sample container S include a peripheral blood container and a venous blood container. Illustratively, the container type detection device includes the container type detection device of any of the embodiments described above.
It will be appreciated that the peripheral blood vessel will typically have a sample in the middle and no sample at the bottom. The venous blood container is typically empty of sample in the middle and sample at the bottom. The container type detecting device is used for detecting the middle part or the bottom part of the sample container so as to determine the container type of the sample container.
In some embodiments, the container type detection device comprises at least one of a capacitive sensor, an opto-coupler sensor, an inductive sensor, a pressure sensor, and the like.
Referring to fig. 2 (D), in some embodiments, the locking assembly 36 includes an electromagnet 361 and an iron tab 362 that cooperates with the electromagnet 361. One of the electromagnet 361 and the iron piece 362 is provided on the holder 31, and the other is provided on the container holder 35. The position of the electromagnet 361 corresponds to the position of the iron piece 362. Illustratively, the electromagnet 361 is disposed on the carrier 31, and the iron piece 362 is disposed on the container holder 35. When the electromagnet 361 is powered off, the locking assembly 36 is in an unlocked state, and the container holder 35 can be driven to swing transversely relative to the carrier holder 31 by a swing driving member (such as a swing motor). When the electromagnet 361 is powered, the locking assembly 36 is in a locked state, and the receptacle 35 cannot swing laterally relative to the receptacle 31.
In other embodiments, the locking assembly 36 may also include a locking tab (not shown) and a locking slot (not shown). One of the locking protrusion and the locking groove is provided on the receptacle 35 and the other is provided on the carrier 31. The locking protrusion is driven to move by a locking motor (not shown) to be inserted into the locking groove in a locked state, and to move out of the locking groove in an unlocked state.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected. Either mechanically or electrically. They may be directly connected or indirectly connected through intervening media, or may be connected through the use of two elements or the interaction of two elements. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
In the present application, unless expressly stated or limited otherwise, the recitation of a first feature "on" or "under" a second feature may include the recitation of the first and second features being in direct contact, and may also include the recitation of the first and second features not being in direct contact, but being in contact with another feature between them. Also, the first feature "on," "above" and "over" the second feature may include the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.
The above disclosure provides many different embodiments or examples for implementing different features of the invention. In order to simplify the disclosure of the present invention, the components and arrangements of the specific examples are described above. Of course, they are merely examples and are not intended to limit the present invention. Furthermore, the present invention may repeat reference numerals and/or reference letters in the various examples, which have been repeated for purposes of simplicity and clarity and do not in themselves dictate a relationship between the various embodiments and/or arrangements discussed. In addition, the present disclosure provides examples of various specific processes and materials, but one of ordinary skill in the art may recognize applications of other processes and/or use of other materials.
In the description of the present specification, reference to the terms "one embodiment," "some embodiments," "an illustrative embodiment," "an example," "a specific example," or "some examples" or the like means that a particular method step, feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the particular method steps, features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily think of various equivalent modifications or replacements within the technical scope of the present invention, and these modifications or replacements should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (27)

1. A peripheral blood mixing mechanism for mixing peripheral blood in a sample container, the peripheral blood mixing mechanism comprising:
the bearing seat is used for bearing the sample container;
the blending driving assembly is connected with the bearing seat and used for driving the bearing seat to move transversely, so that the sample container is driven to move transversely to blend the peripheral blood sample in the sample container.
2. The peripheral blood mixing mechanism of claim 1, wherein the mixing drive assembly is configured to drive the bearing base to reciprocate laterally.
3. The peripheral blood blending mechanism of claim 1, wherein the blending driving component is configured to drive the bearing seat to reciprocate in a curve or a straight line.
4. The peripheral blood mixing mechanism of claim 3, wherein the mixing drive assembly is configured to drive the bearing base to reciprocate in an arc.
5. A peripheral blood mixing mechanism according to claim 1, wherein the holder is adapted to hold an emergency sample container and/or a routine sample container.
6. The peripheral blood blending mechanism of claim 1, wherein the blending driving component is configured to drive the bearing seat to traverse reciprocally 300/min to 800/min.
7. The peripheral blood mixing mechanism of claim 6, wherein the mixing drive assembly is configured to drive the bearing seat to traverse the bearing seat for 800 times/min in a reciprocating manner.
8. The peripheral blood pooling mechanism of claim 1, wherein said pooling drive assembly comprises:
a blending drive member;
and the mixing driving part can drive the mixing driving part to do rotary motion to drive the bearing seat to move transversely.
9. The peripheral blood mixing mechanism of claim 8, wherein the mixing drive member comprises:
and the cam is fixedly connected with the blending driving piece and is in transmission connection with the bearing seat.
10. The peripheral blood mixing mechanism according to claim 9, wherein a bearing is arranged on the bearing seat, and the bearing is in transmission connection with the cam.
11. The peripheral blood mixing mechanism of claim 8, wherein the mixing drive member comprises:
the crank is connected with the blending driving part;
and one end of the crank connecting rod is connected with the crank, and the other end of the crank connecting rod is connected with the bearing seat.
12. The peripheral blood blending mechanism of claim 1, further comprising a blending support, wherein the blending driving assembly is disposed on the blending support; the mixing drive assembly further comprises:
the mixing piece that resets, one end with mixing support butt, the other end with bear the seat butt, be used for resetting bear the seat.
13. The peripheral blood mixing mechanism according to claim 12, wherein the mixing return member includes an elastic member, one end of the elastic member abuts against the mixing support, and the other end of the elastic member abuts against the bearing seat.
14. A peripheral blood pooling mechanism of claim 12 further comprising:
the guide rod is arranged on the blending support and is in sliding fit with the bearing seat.
15. The peripheral blood mixing mechanism of claim 12, wherein the mixing support is provided with a mixing slide rail in sliding fit with the bearing seat, and the mixing drive assembly is configured to drive the bearing seat to slide along the mixing slide rail.
16. A peripheral blood mixing mechanism according to any one of claims 1 to 15, wherein the holder is provided with a receiving groove for receiving the sample container, and the diameter of the receiving groove is larger than that of the sample container.
17. A peripheral blood pooling mechanism according to claim 16 wherein a diameter of said receiving well is 0.5mm-3mm larger than a diameter of said sample container.
18. A peripheral blood mixing mechanism according to any one of claims 1 to 15, wherein the bearing seat is provided with a holding groove for holding the sample container, the holding groove is arranged with a variable diameter, one end of the holding groove is in spacing fit with the sample container, and the diameter of the other end of the holding groove is 0.5mm to 3mm larger than the diameter of the sample container.
19. A peripheral blood mixing mechanism according to any one of claims 1 to 15, wherein the holder is provided with two receiving grooves, each receiving groove being adapted to receive one of the sample containers.
20. A peripheral blood pooling mechanism according to claim 19 wherein one of said two receiving pockets is adapted to buffer said sample container.
21. A peripheral blood mixing mechanism according to any one of claims 1 to 15, wherein the carrying seat is provided with a receiving groove for receiving the sample container, and the receiving groove is provided with a shock absorbing member disposed between a groove wall of the receiving groove and the sample container.
22. The utility model provides a mixing mechanism for the sample in the mixing sample container, its characterized in that, mixing mechanism includes:
a container holder for carrying the sample container;
the bearing seat is connected with the container seat;
the blending driving assembly is connected with the bearing seat and is used for driving the bearing seat to transversely move;
a locking assembly in a locked state when the sample container is of the type of a peripheral blood container, the locking assembly locking the receptacle to limit lateral oscillation of the receptacle relative to the carrier; when the sample container is a venous blood container, the locking assembly is in an unlocked state, and the locking assembly unlocks the container holder so that the container holder can swing transversely relative to the carrier holder.
23. The blending mechanism of claim 22, wherein the bearing seat is provided with two limiting rods for limiting the swing angle of the container seat to not more than 180 degrees.
24. The blending mechanism of claim 22, further comprising:
and the container type detection device is arranged on the bearing seat and is used for detecting the type of the sample container, and the type of the sample container comprises a peripheral blood container and a venous blood container.
25. The blending mechanism of claim 24, wherein the container type detection device comprises at least one of a capacitive sensor, an opto-coupler sensor, an inductive sensor, and a pressure sensor.
26. The blending mechanism of claim 22, wherein the locking assembly comprises: the container comprises an electromagnet and an iron sheet matched with the electromagnet, wherein one of the electromagnet and the iron sheet is arranged on the bearing seat, the other one of the electromagnet and the iron sheet is arranged on the container seat, and the position of the electromagnet corresponds to that of the iron sheet.
27. A sample analyzer, comprising:
the peripheral blood pooling mechanism of any one of claims 1-21 or the pooling mechanism of any one of claims 22-26;
the sampling mechanism is used for collecting the uniformly mixed sample in the sample container; and
a reaction measurement mechanism to which the sampling mechanism injects the collected sample.
CN202221733884.8U 2022-07-05 2022-07-05 Peripheral blood mixing mechanism, mixing mechanism and sample analyzer Active CN218496567U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202221733884.8U CN218496567U (en) 2022-07-05 2022-07-05 Peripheral blood mixing mechanism, mixing mechanism and sample analyzer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202221733884.8U CN218496567U (en) 2022-07-05 2022-07-05 Peripheral blood mixing mechanism, mixing mechanism and sample analyzer

Publications (1)

Publication Number Publication Date
CN218496567U true CN218496567U (en) 2023-02-17

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