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CN1253589A - 来自肺炎链球菌的降解人类补体c3的蛋白酶 - Google Patents

来自肺炎链球菌的降解人类补体c3的蛋白酶 Download PDF

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Publication number
CN1253589A
CN1253589A CN98804470A CN98804470A CN1253589A CN 1253589 A CN1253589 A CN 1253589A CN 98804470 A CN98804470 A CN 98804470A CN 98804470 A CN98804470 A CN 98804470A CN 1253589 A CN1253589 A CN 1253589A
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CN
China
Prior art keywords
protein
streptococcus pneumoniae
nucleic acid
antibody
seq
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Pending
Application number
CN98804470A
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English (en)
Chinese (zh)
Inventor
马格列特·K·霍斯泰特
盖瑞·唐尼
拉克施米·S·南狄瓦答
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University of Minnesota
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University of Minnesota
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Publication date
Application filed by University of Minnesota filed Critical University of Minnesota
Publication of CN1253589A publication Critical patent/CN1253589A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN98804470A 1997-04-24 1998-04-24 来自肺炎链球菌的降解人类补体c3的蛋白酶 Pending CN1253589A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4431697P 1997-04-24 1997-04-24
US60/044,316 1997-04-24

Publications (1)

Publication Number Publication Date
CN1253589A true CN1253589A (zh) 2000-05-17

Family

ID=21931691

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98804470A Pending CN1253589A (zh) 1997-04-24 1998-04-24 来自肺炎链球菌的降解人类补体c3的蛋白酶

Country Status (8)

Country Link
EP (1) EP0977872A1 (pt)
JP (1) JP2001523960A (pt)
KR (1) KR100544594B1 (pt)
CN (1) CN1253589A (pt)
AU (1) AU740153B2 (pt)
BR (1) BR9809405A (pt)
CA (1) CA2283755A1 (pt)
WO (1) WO1998048022A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6676943B1 (en) 1997-04-24 2004-01-13 Regents Of The University Of Minnesota Human complement C3-degrading protein from Streptococcus pneumoniae
KR20010024299A (ko) * 1997-09-24 2001-03-26 리전츠 오브 더 유니버스티 오브 미네소타 스트렙토코쿠스 뉴모니애로부터의 사람 보체 c3 분해단백질분해효소
IL142017A0 (en) * 1998-09-24 2002-03-10 Univ Minnesota Human complement c3-degrading polypeptide from streptococcus pneumoniae

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5194598A (en) * 1996-10-31 1998-05-22 Human Genome Sciences, Inc. (streptococcus pneumoniae) antigens and vaccines

Also Published As

Publication number Publication date
AU7156698A (en) 1998-11-13
KR100544594B1 (ko) 2006-01-24
WO1998048022A1 (en) 1998-10-29
CA2283755A1 (en) 1998-10-29
EP0977872A1 (en) 2000-02-09
BR9809405A (pt) 2000-06-13
WO1998048022A9 (en) 1999-04-15
JP2001523960A (ja) 2001-11-27
KR20010012096A (ko) 2001-02-15
AU740153B2 (en) 2001-11-01

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