CN115445683B

CN115445683B - PRP test tube

Info

Publication number: CN115445683B
Application number: CN202211171132.1A
Authority: CN
Inventors: 张超; 李英川; 陈昂; 张琳浩
Original assignee: Beijing Meijia Yisheng Medical Equipment Co ltd
Current assignee: Beijing Meijia Yisheng Medical Equipment Co ltd
Priority date: 2022-09-24
Filing date: 2022-09-24
Publication date: 2023-08-22
Anticipated expiration: 2042-09-24
Also published as: CN115445683A

Abstract

The application relates to a PRP test tube, which comprises an outer tube, wherein the outer tube comprises a red blood cell chamber at one end and a PRP chamber at one end of the outer tube opposite to the red blood cell chamber, a serum chamber is arranged between the red blood cell chamber and the PRP chamber, and the red blood cell chamber, the serum chamber and the PRP chamber are relatively communicated; the inside of serum cavity is vertical to be provided with the control lever, be provided with the drive on the serum cavity the control lever reciprocates's drive structure, drive the drive structure drives the control lever removes can control the serum cavity respectively with the intercommunication of red blood cell cavity, PRP cavity. The application has the advantages of reducing the difficulty of extracting the platelet concentrate by operators, reducing the mutual penetration and mixing of the platelet concentrate and the connection positions of the upper liquid level and the lower liquid level, and improving the purity of the platelet concentrate extraction.

Description

PRP test tube

Technical Field

The application relates to the field of blood separation devices, in particular to a PRP test tube.

Background

PRP is a platelet concentrate extracted from whole blood by centrifugation and contains high concentrations of platelets (more than 30 growth factors released after platelet activation), leukocytes and fibrin. The PRP can promote bone and soft tissue repair, and after the PRP is activated (the PRP does not need to be activated in an injection body), the PRP releases the regulation and control of more than 30 growth factors including platelet-derived growth factors, transforming factor beta, insulin-like growth factors, vascular endothelial growth factors, epidermal growth factors and the like, and the growth factors can accelerate the differentiation of mesenchymal stem cells, promote the proliferation of osteoblasts and fibroblasts and accelerate the synthesis of fibrin and extracellular matrixes.

The existing PRP test tube is prepared by putting a test tube with collected blood into a centrifuge, then separating into serum, platelet concentrate (PRP) and red blood cells after centrifugation, and then sequentially extracting through an injection needle.

With respect to the related art described above, the inventors considered that, when the PRP test tube is withdrawn from the inside of the centrifuge, the separated serum, platelet concentrate (PRP) and red blood cells remain in a layered state inside the PRP test tube, and that the platelet concentrate (PRP) therein is manually withdrawn, and that the upper serum needs to be withdrawn before the platelet concentrate is withdrawn during the withdrawal.

The operating personnel is in the extraction with the syringe needle from the direct platelet concentrate of inserting of serum in, causes the purity of platelet concentrate to reduce, and because the content of platelet concentrate is lower, leads to its area of contact with upper and lower liquid level great in the inside of the test tube of constant diameter, mixes each other easily, and the degree of difficulty of extraction is great.

Disclosure of Invention

In order to reduce the difficulty of the extraction of platelet concentrate by operators, reduce the mutual penetration and mixing of the platelet concentrate and the connection positions of the upper liquid level and the lower liquid level, and improve the purity of the platelet concentrate extraction, the application provides a PRP test tube.

The PRP test tube provided by the application adopts the following technical scheme:

the PRP test tube comprises an outer tube, wherein the outer tube comprises a red blood cell chamber at one end and a PRP chamber at one end of the outer tube opposite to the red blood cell chamber, a serum chamber is arranged between the red blood cell chamber and the PRP chamber, and the red blood cell chamber, the serum chamber and the PRP chamber are relatively communicated; the inside of serum cavity is vertical to be provided with the control lever, be provided with the drive on the serum cavity the control lever reciprocates's drive structure, drive the drive structure drives the control lever removes can control the serum cavity respectively with the intercommunication of red blood cell cavity, PRP cavity.

By adopting the technical scheme, the control rod is driven to move by the driving structure, so that the opening and closing of the serum chamber and the erythrocyte chamber and the opening and closing of the serum chamber and the PRP chamber are controlled; firstly, the control rod is moved to one end close to the PRP chamber, the PRP chamber and the serum chamber are relatively separated, the serum chamber is relatively communicated with the red blood cell chamber, then blood is injected into the serum chamber, the outer tube is placed into the centrifuge for centrifugation, the centrifuged red blood cells are located in the red blood cell chamber, the PRP serum mixing liquid is located in the serum chamber, the control rod is driven to move to one end close to the red blood cell chamber through the driving structure, the red blood cell chamber and the serum chamber are further separated, the PRP chamber and the serum chamber are relatively communicated, the outer tube is inverted and placed into the centrifuge for centrifugation, so that PRP is separated into the PRP chamber, serum is separated into the serum chamber, the difficulty of extracting platelet concentrate by operators is reduced, the mutual penetration and mixing of the platelet concentrate and the connection positions of the upper liquid surface and the lower liquid surface are reduced, and the purity of platelet concentrate extraction is improved.

Optionally, the drive structure is including the cover establishing the control ring of serum cavity outer wall, the control ring with serum cavity sliding connection, the sliding hole has been seted up to the lateral wall level of serum cavity, just the control ring for the fixed connecting rod that wears to be equipped with in position of sliding hole, the connecting rod with control rod fixed connection, just the control ring can with the sliding hole is sealed completely, the outside of control ring is provided with locking structure.

Through adopting above-mentioned technical scheme, operating personnel passes through the removal control ring, and then the control ring drives the connecting rod and remove to the connecting rod drives the control rod and reciprocates in the inside of serum cavity, the operating personnel of being convenient for is to the regulation of control rod.

Optionally, the locking structure is including articulating first locking lever and the second locking lever on the control ring, the top of first locking lever is close to one side fixedly connected with first locking piece of serum cavity, the bottom of first locking lever is close to one side level of control ring is provided with first elastic component, the bottom of second locking lever is close to one side fixedly connected with second locking piece of serum cavity, the top of second locking lever is close to one side level of control ring is provided with the second elastic component, first locking hole and second locking hole have been seted up to the lateral wall level of serum cavity, works as the control ring drives the control lever removes to the top, first locking piece can stretch into the inside of first locking hole, works as the control ring drives the control lever removes to the bottom, the second locking piece can stretch into the inside of second locking hole.

By adopting the technical scheme, the control ring moves towards one side close to the erythrocyte chamber, so that the first locking rod is driven to move, the first locking block stretches into the first locking hole under the pushing of the first elastic piece, the control ring is locked, and the control rod is locked at the communicating position of the erythrocyte chamber and the serum chamber; the control ring is moved towards one side close to the PRP chamber, and then the second locking rod is driven to move, so that the second locking block stretches into the second locking hole under the pushing of the second elastic piece, the control ring is locked, and the control rod is locked at the communicating position of the PRP chamber and the serum chamber

Optionally, the vertical fixedly connected with go-between in top of PRP cavity, the bottom of serum cavity is for the vertical draw-in groove of seting up in position of go-between, the go-between can be inserted the inside of draw-in groove, the snap ring groove has been seted up to the lateral wall of go-between, the inside horizontal sliding connection of snap ring groove has the fixture block, the fixture block is close to one side level of the tank bottom of snap ring groove is provided with the third elastic component, the serum cavity is located the draw-in groove has been seted up to the draw-in groove level, works as the go-between inserts the inside of draw-in groove, the fixture block can stretch into the inside of draw-in groove, the inside horizontal sliding connection of draw-in groove has the opening part, the one end of opening the side wall of serum cavity stretches out and the relative slip.

Through adopting above-mentioned technical scheme, after PRP and serum centrifugation layering, operating personnel remove through the axis center that is close to the serum cavity with opening the piece orientation for opening the piece and promoting the fixture block and retract to the inside of clamping ring groove, and then be convenient for operating personnel will insert the ring and take out from the inside of inserting the groove, thereby conveniently handle the inside PRP liquid of PRP cavity.

Optionally, the bottom wall of the serum chamber is horizontally and slidably connected with a first sealing piece relative to the position of the insert ring, a second sealing piece is horizontally and slidably connected with the insert ring relative to the lower part of the first sealing piece, the first sealing piece and the second sealing piece can completely cover the communication position of the serum chamber and the PRP chamber, one end of the first sealing piece extends from the side wall of the serum chamber, and one end of the second sealing piece extends from the side wall of the PRP chamber.

Through adopting above-mentioned technical scheme, through remove first sealing fin and second sealing fin towards the one side that is close to the second intercommunicating pore to can carry out the sealed shutoff to the position department of second intercommunicating pore, and then reduce when taking out the PRP cavity from the below of serum cavity, the inside liquid and the external contact of PRP cavity and serum cavity produce the circumstances of pollution.

Optionally, the lateral wall level of control lever has seted up first seal ring groove, the inside fixedly connected with gasbag of first seal ring groove, the inside packing of gasbag has the counter weight sand piece, serum cavity with the lateral wall of red blood cell cavity hookup location department serum cavity with the lateral wall of PRP cavity hookup location department has respectively the level and has seted up the second seal ring groove, works as the control lever is located top and bottom position department respectively, first seal ring groove with the second seal ring groove is relative.

Through adopting above-mentioned technical scheme, when removing the control lever to the highest or the extreme down, first sealed annular is relative with the sealed annular of second, and then when putting into the inside of centrifuge with the outer tube, drive the high-speed rotation of outer tube through centrifuge to drive the inside counter weight sand piece of being located the gasbag and throw away towards one side that deviates from the control lever center, and then drive the gasbag and expand, thereby tightly compress tightly the gasbag on the lateral wall of the sealed annular of second, improve the sealed effect of control lever and first communication hole, control lever and second intercommunicating pore position department.

Optionally, an elastic pull rope is horizontally arranged in the air bag, one end of the elastic pull rope is fixedly connected with the air bag, and the other end of the elastic pull rope is fixedly connected with the control rod.

Through adopting above-mentioned technical scheme, through the elasticity stay cord that sets up for under the effect that does not have the centrifugation, the elasticity stay cord can draw back the gasbag to the inside of first seal ring groove, reduces the condition of gasbag card between the lateral wall of control rod and serum cavity.

Optionally, the one end that the serum cavity is close to red blood cell cavity is provided with first slope lateral wall, first slope lateral wall is along the direction of height gradually towards red blood cell cavity's one end throat setting, the one end that the serum cavity is close to PRP cavity is provided with the second slope lateral wall setting, the second slope lateral wall is along the direction of height gradually towards PRP cavity's one end throat setting, red blood cell cavity with PRP cavity is provided with adjustment structure respectively.

By adopting the technical scheme, the cross-sectional areas of the positions of the red blood cell chamber and the serum chamber are reduced through the arranged first inclined side wall, so that the liquid level position between the red blood cell and the PRP serum mixed liquid can be accurately adjusted through the adjusting structure, and the liquid can be accurately extracted by operators; the cross-sectional area of the PRP chamber and the serum chamber position is reduced through the second inclined side wall, so that the liquid level position between the serum and the PRP liquid can be accurately adjusted through the adjusting structure, and the liquid can be accurately extracted by operators.

Optionally, the adjusting structure includes a first fixing portion fixedly connected with the serum chamber, one end of the first fixing portion, which is away from the serum chamber, is provided with a first adjusting portion, the first adjusting portion is connected with the first fixing portion through threads, a first sealing member is fixedly connected with the inside of the first adjusting portion, and an outer side wall of the first sealing member is in abutting sliding connection with an inner side wall of the first fixing portion; the PRP chamber comprises a second fixing part fixedly connected with the serum chamber, a second adjusting part is arranged at one end, deviating from the serum chamber, of the second fixing part, the second adjusting part is connected with the second fixing part through threads, a second sealing element is fixedly connected to the inside of the second adjusting part, and the outer side wall of the second sealing element is in butt sliding with the inner side wall of the second fixing part.

Through adopting above-mentioned technical scheme, through rotating first regulation portion for first regulation portion moves towards the one side that deviates from first fixed part, adjusts the size of the inside cavity of erythrocyte cavity, and then adjusts according to the volume of erythrocyte liquid, makes erythrocyte liquid can be located the inside of erythrocyte cavity completely; through rotating second adjustment portion for second adjustment portion moves towards one side that deviates from the second fixed part, adjusts the size of PRP cavity inside cavity, and then adjusts according to PRP's volume, makes PRP can be located the inside of PRP cavity completely.

In summary, the present application includes at least one of the following beneficial technical effects:

1. the control rod is driven to move through the driving structure, so that the opening and closing of the serum chamber and the red blood cell chamber and the opening and closing of the serum chamber and the PRP chamber are controlled; firstly, the control rod is moved to one end close to the PRP chamber, the PRP chamber and the serum chamber are relatively separated, the serum chamber is relatively communicated with the red blood cell chamber, then blood is injected into the serum chamber, the outer tube is placed into the centrifuge for centrifugation, the centrifuged red blood cells are located in the red blood cell chamber, the PRP serum mixing liquid is located in the serum chamber, the control rod is driven to move to one end close to the red blood cell chamber through the driving structure, the red blood cell chamber and the serum chamber are further separated, the PRP chamber and the serum chamber are relatively communicated, the outer tube is inverted and placed into the centrifuge for centrifugation, so that PRP is separated into the PRP chamber, serum is separated into the serum chamber, the difficulty of extracting platelet concentrate by operators is reduced, the mutual penetration and mixing of the platelet concentrate and the connection positions of the upper liquid surface and the lower liquid surface are reduced, and the purity of platelet concentrate extraction is improved.

2. The operating personnel passes through the removal control ring, and then the control ring drives the connecting rod and removes to the connecting rod drives the control rod and reciprocates in the inside of serum cavity, and the operating personnel of being convenient for is to the regulation of control rod.

3. After PRP and serum centrifugation layering, operating personnel remove through the axis center that is close to the serum cavity with the opening part orientation for the opening part promotes the fixture block and contracts the inside of card solid annular, and then the operating personnel of being convenient for take out the insert ring from the inside of inserting the groove, thereby conveniently handles the inside PRP liquid of PRP cavity.

Drawings

FIG. 1 is a schematic diagram of the overall structure of a PRP cuvette according to an embodiment of the present application;

FIG. 2 is a side view of the overall structure of a PRP cuvette in an embodiment of the application;

FIG. 3 is a cross-sectional view of the overall structure of a PRP cuvette according to an embodiment of the present application;

FIG. 4 is a cross-sectional view of a PRP tube in accordance with an embodiment of the present application, at a serum chamber location;

FIG. 5 is an enlarged view of portion A of FIG. 4;

FIG. 6 is a schematic diagram of a PRP test tube according to an embodiment of the present application when the opening block is not pushed in;

fig. 7 is a schematic diagram of a PRP test tube according to an embodiment of the present application when the opening block is pushed in.

Reference numerals illustrate: 1. an outer tube; 2. a red blood cell chamber; 21. a first fixing portion; 211. a first external thread; 22. a first adjusting part; 221. a first internal thread; 23. a first sealing block; 24. a first extraction aperture; 3. a serum chamber; 31. a first sloped sidewall; 311. a first communication hole; 32. a second sloped sidewall; 321. a second communication hole; 33. a liquid inlet; 34. an air outlet; 35. a control lever; 351. a first seal ring groove; 352. an air bag; 353. an elastic pull rope; 36. a sliding hole; 37. a first locking hole; 38. a second locking hole; 39. a second seal ring groove; 310. an insertion groove; 3101. a clamping groove; 3102. opening the block; 3103. an opening lever; 3104. a tension spring; 3105. a first chute; 3106. a first sealing sheet; 31061. a first hard plate; 3107. a second chute; 3108. a second sealing sheet; 31081. a second hard plate; 3109. plugging paper; 3110. an operation hole; 4. a PRP chamber; 41. an insert ring; 411. a clamping ring groove; 412. a clamping block; 413. a third spring; 42. a second fixing portion; 421. a second external thread; 43. a second adjusting part; 431. a second internal thread; 44. a second sealing block; 45. a second extraction hole; 5. a driving structure; 51. a control loop; 52. a connecting rod; 53. a first locking lever; 531. a first locking block; 532. a first spring; 54. a second locking lever; 541. a second locking block; 542. and a second spring.

Detailed Description

The application is described in further detail below with reference to fig. 1-7.

The embodiment of the application discloses a PRP test tube. Referring to fig. 1 and 2, a PRP test tube includes a vertically arranged outer tube 1, wherein the outer tube 1 includes a red blood cell chamber 2 at the top, a serum chamber 3 below the red blood cell chamber 2, and a PRP chamber 4 below the serum chamber 3. The red blood cell chamber 2, the serum chamber 3 and the PRP chamber 4 are relatively communicated.

Referring to fig. 2 and 3, the serum chamber 3 and the red blood cell chamber 2 are connected by a first inclined sidewall 31, the first inclined sidewall 31 is gradually tapered along the height direction, and a first communication hole 311 for connecting the serum chamber 3 and the red blood cell chamber 2 is reserved in the center of the first inclined sidewall 31.

The serum chamber 3 and the PRP chamber 4 are connected by a second inclined wall 32, the second inclined wall 32 is gradually arranged toward the shrinkage of one side of the PRP chamber 4 along the height direction, and a second communication hole 321 for communicating the serum chamber 3 and the PRP chamber 4 is reserved at the center of the second inclined wall 32.

The side wall of the serum chamber 3 is close to one side of the PRP chamber 4 and is provided with a liquid inlet 33, the liquid inlet 33 is used for communicating the outside with the inside of the serum chamber 3 relatively, a silica gel cap is plugged at the position of the liquid inlet 33, and an operator can inject blood into the inside of the serum chamber 3 through an injector.

The side wall of the serum chamber 3 is also provided with an air outlet 34, the air outlet 34 is opposite to the liquid inlet 33, the air outlet 34 is used for communicating the outside with the inside of the serum chamber 3, a silica gel cap is blocked at the position of the air outlet 34, and when blood is injected into the inside of the serum chamber 3, the silica gel cap is opened for exhausting, so that liquid is convenient to inject.

Referring to fig. 3 and 4, a control rod 35 is coaxially provided in the serum chamber 3, and a tip end of the control rod 35 is opposed to the first communication hole 311 and a base end of the control rod 35 is opposed to the second communication hole 321. The outside of the serum chamber 3 is provided with a driving structure 5 for driving the control lever 35 to move up and down.

The driving structure 5 comprises a control ring 51 sleeved outside the serum chamber 3, the control ring 51 is in butt joint with the outer side wall of the serum chamber 3 and slides relatively, a connecting rod 52 is horizontally fixedly connected to the control rod 35, a sliding hole 36 is horizontally formed in the side wall of the serum chamber 3 relative to the position of the connecting rod 52, and the connecting rod 52 penetrates through the sliding hole 36 and is connected relatively in a sliding mode. The connecting rod 52 is fixedly connected with the control ring 51.

The outer side wall of the control ring 51 is hinged with a first locking lever 53 and a second locking lever 54, the first locking lever 53 and the second locking lever 54 are both vertically arranged, and the first locking lever 53 and the second locking lever 54 are oppositely arranged along the axial direction of the control ring 51.

One side of the top end of the first locking rod 53, which is close to the serum chamber 3, is fixedly connected with a first locking block 531, one end of the bottom end of the first locking rod 53, which is close to the serum chamber 3, is horizontally provided with a first spring 532, one end of the first spring 532 is fixedly connected with the first locking rod 53, and the other end of the first spring 532 is fixedly connected with the control ring 51. The first locking rod 53 is pushed by the first spring 532, and thus the first locking rod 53 pushes the first locking block 531 to be pressed against the side wall of the serum chamber 3 and to slide relatively.

One side of the bottom end of the second locking rod 54, which is close to the serum chamber 3, is fixedly connected with a second locking block 541, and one end of the top end of the second locking rod 54, which is close to the serum chamber 3, is horizontally provided with a second spring 542, one end of the second spring 542 is fixedly connected with the second locking rod 54, and the other end of the second spring 542 is fixedly connected with the control ring 51. The second locking rod 54 is pushed by the second spring 542, and the second locking rod 54 further pushes the second locking block 541 to be pressed against the side wall of the serum chamber 3 and slide relatively.

The outer side wall of the serum chamber 3 is horizontally provided with a first locking hole 37 relative to the vertical direction of the first locking block 531, when the control rod 35 is driven by the control ring 51 to extend into the first communication hole 311, the first locking block 531 is opposite to the first locking hole 37, and the first spring 532 pushes the first locking block 531 to enter into the first locking hole 37, so that the position of the control ring 51 is fixed, and then the position of the control rod 35 is fixed.

The second locking hole 38 is horizontally formed in the outer side wall of the serum chamber 3 relative to the vertical direction of the second locking block 541, when the control ring 51 drives the control rod 35 to extend into the second communication hole 321, the second locking block 541 is opposite to the second locking hole 38, and the second spring 542 pushes the second locking block 541 to enter into the second locking hole 38, so that the position of the control ring 51 is fixed, and further, the position of the control rod 35 is fixed.

Referring to fig. 4 and 5, first seal ring grooves 351 are formed at both ends of a side wall of the control rod 35, the first seal ring grooves 351 are annular groove bodies, and the first seal ring grooves 351 and the control rod 35 are coaxially arranged. The second seal ring groove 39 is formed coaxially with the inner wall of the first communication hole 311 and the inner wall of the second communication hole 321 of the serum chamber 3. When the control lever 35 moves to the topmost end, the first seal ring groove 351 is opposed to the second seal ring groove 39 located inside the first communication hole 311, and when the control lever 35 moves to the bottommost end, the first seal ring groove 351 is opposed to the second seal ring groove 39 located inside the second communication hole 321.

The inside fixedly connected with gasbag 352 of first sealed annular 351, the inside of gasbag 352 is filled with the counter weight grit, and the inside level of gasbag 352 is provided with elasticity stay cord 353, and the one end and the gasbag 352 fixed connection of elasticity stay cord 353, fixed connection between the other end and the control rod 35 of elasticity stay cord 353.

When first sealing ring groove 351 and second sealing ring groove 39 are relative, put into centrifuge's inside with outer tube 1, centrifuge drives outer tube 1 high-speed rotation, and then drives the inside counter weight grit centrifugal rotation of being located gasbag 352, throws away towards one side that deviates from control rod 35 axle center, and then struts gasbag 352, stretches into the inside of second sealing ring groove 39 with gasbag 352, and then tightly compress tightly the fixing on the lateral wall of second sealing ring groove 39 with gasbag 352, improves sealing performance.

Referring to fig. 6 and 7, an insert ring 41 is coaxially and fixedly connected to the top end of the prp chamber 4, and an insert groove 310 is vertically formed in the bottom wall of the serum chamber 3 relative to the position of the insert ring 41, and the insert ring 41 is slidably connected to the serum chamber 3. The side wall of the insert ring 41 is horizontally provided with a clamping ring groove 411, the inside of the clamping ring groove 411 is horizontally connected with a clamping block 412 in a sliding manner, one side of the clamping block 412, which is close to the bottom of the clamping ring groove 411, is horizontally provided with a third elastic piece 413, one end of the third elastic piece 413 is fixedly connected with the clamping block 412, and the other end of the third elastic piece 413 is fixedly connected with the insert ring 41.

The clamping groove 3101 is horizontally formed in the serum chamber 3 relative to the clamping block 412, an opening block 3102 is horizontally and slidably connected in the clamping groove 3101, an opening rod 3103 is horizontally and fixedly connected to one side, close to the bottom of the clamping groove 3101, of the opening block 3102, and the opening rod 3103 extends out of the side wall of the serum chamber 3 and is in relative sliding connection. One side of the opening block 3102, which is close to the bottom of the clamping groove 3101, is horizontally provided with a tension spring 3104, one end of the tension spring 3104 is fixedly connected with the opening block 3102, and the other end of the tension spring 3104 is fixedly connected with the serum chamber 3.

When the insert ring 41 is inserted into the insert groove 310, the locking ring groove 411 is opposite to the locking groove 3101, and the third spring pushes the locking block 412 to be inserted into the locking groove 3101, thereby fixing the insert ring 41 inside the insert groove 310. When it is necessary to take out the insert ring 41 from the inside of the insert groove 310, the opening lever 3103 is pushed toward one side of the insert ring 41, and the opening block 3102 pushes the latch 412 to retract into the inside of the latch groove 411, thereby sliding the insert ring 41 out of the inside of the insert groove 310.

The serum chamber 3 is provided with a first runner 3105 horizontally provided at the top end of the insertion groove 310, the first runner 3105 is communicated with the second communication hole 321, a first sealing piece 3106 is provided horizontally inside the first runner 3105, the first sealing piece 3106 is slidingly connected with the serum chamber 3, and one end of the first sealing piece 3106 protrudes from the side wall of the serum chamber 3.

The serum chamber 3 is located below the first chute 3105 and is horizontally provided with a second chute 3107, the second chute 3107 is horizontally provided with a second sealing plate 3108 inside, the second sealing plate 3108 is slidably connected with the insert ring 41, and one end of the second sealing plate 3108 extends from the side wall of the serum chamber 3.

The first chute 3105 and the second chute 3107 are vertically provided with a blocking paper 3109 at a side close to the second communication hole 321, a top end of the blocking paper 3109 is fixedly connected with the serum chamber 3, and a bottom end of the blocking paper 3109 is fixedly connected with the insert ring 41. A first hard plate 31061 is fixedly connected to one side of the first sealing sheet 3106 close to the sealing paper 3109, and a second hard plate 31081 is fixedly connected to one side of the second sealing sheet 3108 close to the sealing paper 3109.

The side wall of the serum chamber 3 is horizontally opened with an operation hole 3110 with respect to the positions of the first sealing sheet 3106 and the second sealing sheet 3108. When the operator pushes the first sealing sheet 3106 and the second sealing sheet 3108 into the second communication hole 321, the first sealing sheet 3106 and the second sealing sheet 3108 can completely shield the second communication hole 321, so that the PRP chamber 4 is removed from the lower end of the serum chamber 3, and the operator can conveniently extract the blood inside the PRP chamber.

Referring to fig. 2 and 3, the erythrocyte chamber 2 includes a first fixing portion 21 near one side of the serum chamber 3, and a first adjusting portion 22 is sleeved on the outer side of the first fixing portion 21 away from the serum chamber 3. The outer side wall of the first fixing portion 21 is provided with a first external thread 211, the inner side wall of the first adjusting portion 22 is provided with a first internal thread 221, and the first external thread 211 and the first internal thread 221 are engaged with each other relatively. The first sealing block 23 is coaxially and fixedly connected to the inside of the first adjusting portion 22, and the outer side wall of the first sealing block 23 is in contact with and slides relatively against the inner side wall of the first fixing portion 21. The first adjusting portion 22 has a first extraction hole 24 formed in the center thereof, and an operator can pass through the first extraction hole 24 by using a syringe to extract the liquid in the erythrocyte chamber 2 by passing through the first sealing block 23.

By rotating the first adjustment part 22, the first adjustment part 22 is further moved towards the side facing away from the first fixing part 21, thereby adjusting the size of the cavity inside the red blood cell chamber 2.

The PRP chamber 4 comprises a second fixing part 42 close to one side of the serum chamber 3, and a second adjusting part 43 is sleeved on the outer side of the second fixing part 42 away from the serum chamber 3. The second external thread 421 is provided on the outer sidewall of the second fixing portion 42, and the second internal thread 431 is provided on the inner sidewall of the second adjusting portion 43, and the second external thread 421 and the second internal thread 431 are engaged with each other. The second sealing block 44 is coaxially and fixedly connected to the inside of the second adjusting portion 43, and the outer side wall of the second sealing block 44 abuts against and slides relatively against the inner side wall of the second fixing portion 42. A second extraction hole 45 is formed in the center of the second adjusting portion 43, and an operator can pass through the second extraction hole 45 by using a syringe to extract the liquid in the PRP chamber 4 by penetrating the second sealing block 44.

By rotating the second adjustment part 43, the second adjustment part 43 is thereby moved towards the side facing away from the second fixing part 42, thereby adjusting the size of the cavity inside the PRP chamber 4.

The implementation principle of the PRP test tube of the embodiment of the application is as follows: firstly, the red blood cell chamber 2 is positioned below the serum chamber 3, blood is injected into the serum chamber 3 from the liquid inlet 33 through the injector, the control ring 51 is pushed to move towards one side close to the PRP chamber 4, then the control ring 51 is fixed by extending into the second locking hole 38 through the second locking block 541, and then the control rod 35 extends into the second communication hole 321, so that the PRP chamber 4 is separated from the serum chamber 3, and the red blood cell chamber 2 is relatively communicated with the serum chamber 3.

The outer tube 1 is placed in the centrifuge for the first centrifugation, so that the red blood cell liquid and the PRP serum mixed liquid are layered, the density of the red blood cell liquid is larger than that of the PRP serum mixed liquid, the space in the red blood cell chamber 2 is adjusted by adjusting the first adjusting part 22, the red blood cell liquid is completely located in the red blood cell chamber 2, and the PRP serum mixed liquid is completely located in the serum chamber 3.

The control ring 51 is moved toward the side close to the red blood cell chamber 2, and then the first locking block 531 is extended into the inside of the first locking hole 37, so that the control lever 35 completely closes the first communication hole 311, whereby the red blood cell chamber 2 is separated from the serum chamber 3, and the PRP chamber 4 is relatively communicated with the serum chamber 3.

The outer tube 1 is inverted so that the PRP chamber 4 is located below the serum chamber 3. The outer tube 1 is placed in the centrifuge for secondary centrifugation, PRP and serum are layered, the density of the PRP is higher than that of the serum, the PRP is located below the serum, the size of the inner space of the PRP chamber 4 is adjusted by adjusting the second adjusting part 43, the PRP is located in the PRP chamber 4 completely, and the serum is located in the serum chamber 3 completely.

The first sealing sheet 3106 and the second sealing sheet 3108 are pushed into the inside of the second communication hole 321 so that the serum chamber 3 is completely sealed by the first sealing sheet 3106 and the PRP chamber 4 is completely sealed by the second sealing sheet 3108, thereby removing the insert ring 41 from the inside of the insert groove 310, thereby facilitating the subsequent operation of the PRP inside the PRP chamber 4.

The above embodiments are not intended to limit the scope of the present application, so: all equivalent changes in structure, shape and principle of the application should be covered in the scope of protection of the application.

Claims

1. A PRP test tube, characterized by: the device comprises an outer tube (1), wherein the outer tube (1) comprises a red blood cell chamber (2) at one end and a PRP chamber (4) at one end of the outer tube (1) opposite to the red blood cell chamber (2), a serum chamber (3) is arranged between the red blood cell chamber (2) and the PRP chamber (4), and the red blood cell chamber (2), the serum chamber (3) and the PRP chamber (4) are relatively communicated; a control rod (35) is vertically arranged in the serum chamber (3), a driving structure (5) for driving the control rod (35) to move up and down is arranged on the serum chamber (3), and the driving structure (5) drives the control rod (35) to move so as to control the serum chamber (3) to be communicated with the erythrocyte chamber (2) and the PRP chamber (4) respectively;

the driving structure (5) comprises a control ring (51) sleeved on the outer wall of the serum chamber (3), the control ring (51) is in sliding connection with the serum chamber (3), a sliding hole (36) is horizontally formed in the side wall of the serum chamber (3), a connecting rod (52) is fixedly arranged at the position of the control ring (51) relative to the sliding hole (36), the connecting rod (52) is fixedly connected with the control rod (35), the control ring (51) can completely seal the sliding hole (36), and a locking structure is arranged on the outer side of the control ring (51);

a first sealing ring groove (351) is horizontally formed in the side wall of the control rod (35), an air bag (352) is fixedly connected to the inside of the first sealing ring groove (351), a counterweight sand block is filled in the air bag (352), a second sealing ring groove (39) is horizontally formed in the side wall of the position where the serum chamber (3) is connected with the red blood cell chamber (2) and the side wall of the position where the serum chamber (3) is connected with the PRP chamber (4), and when the control rod (35) is located at the topmost position and the bottommost position respectively, the first sealing ring groove (351) is opposite to the second sealing ring groove (39); the locking structure comprises a first locking rod (53) and a second locking rod (54) which are hinged to the control ring (51), a first locking block (531) is fixedly connected to one side, close to the serum chamber (3), of the top end of the first locking rod (53), a first elastic piece is horizontally arranged on one side, close to the control ring (51), of the bottom end of the first locking rod (53), a second locking block (541) is fixedly connected to one side, close to the serum chamber (3), of the bottom end of the second locking rod (54), a second elastic piece is horizontally arranged on one side, close to the control ring (51), of the top end of the second locking rod (54), a first locking hole (37) and a second locking hole (38) are horizontally arranged on the side wall of the serum chamber (3), when the control ring (51) drives the control rod (35) to move to the top end, the first locking block (531) can extend into the first locking hole (37), and when the control ring (54) drives the control rod (35) to move to the bottom end, the second locking block (541) can extend into the second locking hole (541);

an elastic pull rope (353) is horizontally arranged in the air bag (352), one end of the elastic pull rope (353) is fixedly connected with the air bag (352), and the other end of the elastic pull rope (353) is fixedly connected with the control rod (35).

2. A PRP test tube according to claim 1, characterized in that: the utility model discloses a blood serum collection device, including PRP cavity (4), blood serum cavity (3), insert ring (41) are vertically fixedly connected with on top of PRP cavity (4), insert groove (310) have been vertically seted up for the bottom of blood serum cavity (3) in the position of insert ring (41), insert ring (41) can insert the inside of insert groove (310), clamping annular (411) have been seted up to the lateral wall of insert ring (41), the inside horizontal sliding connection of clamping annular (411) has fixture block (412), one side level that fixture block (412) is close to the tank bottom of clamping annular (411) is provided with the third elastic component, blood serum cavity (3) are located insert groove (310) level has seted up draw-in groove (3101), works as insert ring (41) insert when the inside of insert groove (310), fixture block (412) can stretch into the inside of draw-in groove (3101), the inside horizontal sliding connection of draw-in groove (3101) has the piece of opening, the one end of opening piece is followed blood serum cavity (3) stretches out and slides relatively.

3. A PRP test tube according to claim 2, characterized in that: the bottom wall of the serum chamber (3) is horizontally and slidably connected with a first sealing plate (3106) relative to the position of the insertion ring (41), a second sealing plate (3108) is horizontally and slidably connected with the lower part of the first sealing plate (3106) on the insertion ring (41), the communication positions of the serum chamber (3) and the PRP chamber (4) can be completely shielded by the first sealing plate (3106) and the second sealing plate (3108), one end of the first sealing plate (3106) extends from the side wall of the serum chamber (3), and one end of the second sealing plate (3108) extends from the side wall of the PRP chamber (4).

4. A PRP test tube according to claim 1, characterized in that: the one end that serum cavity (3) is close to red blood cell cavity (2) is provided with first slope lateral wall (31), first slope lateral wall (31) are along the one end throat setting of direction of height towards red blood cell cavity (2) gradually, one end that serum cavity (3) is close to PRP cavity (4) is provided with second slope lateral wall (32) and sets up, second slope lateral wall (32) are along the one end throat setting of direction of height towards PRP cavity (4) gradually, red blood cell cavity (2) with PRP cavity (4) are provided with regulation structure respectively.

5. The PRP test tube of claim 4, wherein: the adjusting structure comprises a first fixing part (21) fixedly connected with the serum chamber (3), a first adjusting part (22) is arranged at one end, deviating from the serum chamber (3), of the first fixing part (21), the first adjusting part (22) is connected with the first fixing part (21) through threads, a first sealing element is fixedly connected to the inside of the first adjusting part (22), and the outer side wall of the first sealing element is in butt sliding with the inner side wall of the first fixing part (21); the PRP chamber (4) comprises a second fixing part (42) fixedly connected with the serum chamber (3), one end of the second fixing part (42) deviating from the serum chamber (3) is provided with a second adjusting part (43), the second adjusting part (43) is connected with the second fixing part (42) through threads, a second sealing element is fixedly connected to the inside of the second adjusting part (43), and the outer side wall of the second sealing element is in butt sliding with the inner side wall of the second fixing part (42).