CN102579652A - Medicine for treating lumbar disc herniation and preparation method thereof - Google Patents
Medicine for treating lumbar disc herniation and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating lumbar disc herniation and a preparation method thereof. The medicine is prepared by radix angelicae pubescentis, loranthus parasiticus, radix angelicae, ligusticum wallichii, notopterygium roots, caulis piperis futokadsurae, sargentg loryvine, ramulus mori, radix clematidis, pseudo-ginseng, astragalus mongholicus, angelica sinensis, radix paeoniae alba, caulis spatholobi, aalty cortex eucommiae, medicinal cyathula roots, teasel roots, drynaria rhizome, rhizoma cibotii, herba epimedii, golden cypress and pachyrhizua angulatus which are evenly mixed. After being crushed, the mixture is evenly mixed with frankincense and myrrh with the formula amount, and 70%-95% (V/V) ethanol is utilized to perform heating, reflux and extraction for two to three times. Each extraction lasts for one to three hours, filtrate is filtered and merged, the ethanol is recovered, the filtrate is concentrated to thick paste with relative density ranging from 1.05 to 1.35 under 60 DEG C, menthol crystal and borneol are added into the thick paste, and the thick paste is evenly stirred and then prepared into various different preparations. The medicine for treating lumbar disc herniation adopts more than twenty raw material medicines for matching and jointly increasing effects of nourishing liver, tonifying kidneys, removing coldness and damp, promoting qi, activating blood circulation and clearing and activating channels and collaterals, has good curative effects on a lumbar disc herniation disease, and has no side effects. The recurrence rate is extremely low.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of medicine of treating prolapse of lumbar intervertebral disc and preparation method thereof.
Background technology
(lumbar disc herniation is the commonly encountered diseases and the frequently-occurring disease of orthopaedics LDH) to prolapse of lumbar intervertebral disc, is the modal reason of lumbago and skelalgia.The most scholars of its pathogenesis think main relevant with damage and degenerative change; On the basis of lumbar intervertebral disc generation degenerative change; Under external force; Annulus fibrosus disci intervertebralis breaks, vertebral pulp is outstanding from rent, tissues such as stimulation or pressuring neural root, blood vessel or spinal cord, or because inflammatory stimulus etc. cause lumbago, sciatic nerve radiated pain and swelling, numbness, symptom such as unable.Hurried because of its morbidity, state of an illness delay has greatly influenced people's operate as normal and life.Prolapse of lumbar intervertebral disc is the common cause of lumbago and skelalgia, has research data to show, 50～60% people lumbago and skelalgia occurred at different times in life, and wherein prolapse of lumbar intervertebral disc accounts for 1/2.
The Therapeutic Method of prolapse of lumbar intervertebral disc is divided into operative therapy, minimally-invasive treatment and conservative treatment three major types clinically at present.The operative therapy wound is big, and recovery time is long, and expense is high, possibly develop complications with postoperative in the art, and relapse rate reaches 2～9%; The minimally-invasive treatment wound is little, and recovery time is short, but receives the restriction of factors such as equipment, specification requirement, and its to apply the time shorter, so safety and long-term effect still remain observation.Because the limitation of operative therapy and minimally-invasive treatment, the treatment of prolapse of lumbar intervertebral disc all should be the beginning with conservative treatment (non-operative treatment) in principle.The conservative treatment of prolapse of lumbar intervertebral disc mainly contains traction, massage, acupuncture, physiotherapy and Chinese medicine, western medicine etc., and simple traction, massage, acupuncture and physiotherapy effective percentage are not high, can't in time alleviate patient's pain; Western medicine adopts oral non-steroidal anti-inflammatory drug usually or adopts hormone and anaesthetic to carry out block therapy, but its side effect is bigger; Treatment by Chinese herbs adopts some Chinese herbal medicine to carry out prescription usually, processing external preparation or oral preparations is treated, and has obtained better therapeutic effect.Like publication number is the patent of invention of CN102125672A; A kind of Chinese medicine medicine of treating cervical vertebra/lumbar disease is disclosed; With Flos Carthami, Ramulus Cinnamomi, Caulis Spatholobi, Rhizoma Curcumae Longae, the Radix Rehmanniae, windproof, Herba speranskiae tuberculatae, triangular, Rhizoma Curcumae, Fructus Chaenomelis, Fructus Aurantii, Radix Achyranthis Bidentatae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Gentianae Macrophyllae, Radix Salviae Miltiorrhizae, Herba Lycopodii, Herba Pyrolae, Caulis Piperis Kadsurae, Fructus Zanthoxyli, Rumalus sophorae, Ramulus Salicis Babylonicae, Rhizoma Anemones Raddeanae, Flos Lonicerae, Cortex Phellodendri, Polyporus, Radix Glycyrrhizae, Semen Persicae, Herba Leonuri, Radix Aconiti, Semen Strychni, Radix Aconiti Kusnezoffii, Eupolyphaga Seu Steleophaga, Olibanum, Myrrha, Radix Rehmanniae Preparata, Rhizoma Paridis, Semen Sinapis Albae, Cortex Cinnamomi, Rhizoma Corydalis, Zaocys, Scolopendra, Rhizoma Atractylodis, Rhizoma Chuanxiong, Pheretima, Herba Ephedrae, Radix Angelicae Sinensis, Radix Clematidis, Flos Daturae, Radix Alangii, Radix Dipsaci, the Radix Angelicae Dahuricae, Caulis Akebiae, Carapax Trionycis, Fructus Xanthii, Sanguis Draxonis, Radix Notoginseng, Herba Asari, Borneolum Syntheticum, Camphora, dried black chicken blood, Holotrichia diomphalia Bates, Calomelas and Plumbum preparatium is the plaster that raw material is processed; Joint disease such as treatment cervical spondylosis, prolapse of lumbar intervertebral disc, scapulohumeral periarthritis, hyperosteogeny, arthritis there is curative effect preferably; But raw material is more in this invention prescription, and its preparation method is comparatively complicated.
Summary of the invention
The technical problem that the present invention will solve provides a kind of good effect, method for preparing and simply treats medicine of prolapse of lumbar intervertebral disc and preparation method thereof.
The medicine of treatment prolapse of lumbar intervertebral disc of the present invention is to be processed by following materials of weight proportions:
Radix Angelicae Pubescentis 20～160 Herba Taxillis 30～180 Radixs Angelicae Dahuricae 20～160
Rhizoma Chuanxiong 20～160 Rhizoma Et Radix Notopterygiis 30～180 Caulis Piperis Kadsuraes 30～180
Caulis Sargentodoxae 30～180 Ramulus Moris 30～180 Radix Clematidis 30～180
Radix Notoginseng 30～100 Radixs Astragali 30～100 Radix Angelicae Sinensis 30～180
The Radix Paeoniae Alba 20～160 Caulis Spatholobis 20～160 Cortex Eucommiae(processed with salt) 20～160
Radix Cyathulae 20～160 Radix Dipsacis 30～180 Rhizoma Drynariae 30～180
Rhizoma Cibotii 30～180 Herba Epimedii 30～120 Cortex Phellodendris 20～160
Pachyrhizua angulatus 20～160 Olibanums 10～100 Myrrhas 10～100
Mentholum 10～100 Borneolum Syntheticums 20～160.
The weight proportion of above-mentioned each raw material is preferably:
Radix Angelicae Pubescentis 50～100 Herba Taxillis 60～120 Radixs Angelicae Dahuricae 50～100
Rhizoma Chuanxiong 60～120 Rhizoma Et Radix Notopterygiis 60～120 Caulis Piperis Kadsuraes 60～120
Caulis Sargentodoxae 30～150 Ramulus Moris 80～150 Radix Clematidis 50～100
Radix Notoginseng 50～100 Radixs Astragali 50～100 Radix Angelicae Sinensis 60～120
The Radix Paeoniae Alba 50～100 Caulis Spatholobis 60～120 Cortex Eucommiae(processed with salt) 60～120
Radix Cyathulae 30～80 Radix Dipsacis 30～80 Rhizoma Drynariae 30～80
Rhizoma Cibotii 30～80 Herba Epimedii 60～100 Cortex Phellodendris 50～100
Pachyrhizua angulatus 50～100 Olibanums 10～60 Myrrhas 10～60
Mentholum 10～40 Borneolum Syntheticums 50～120.
The dosage form of said medicine can be tincture, gel or plaster, is preferably plaster.
The method for preparing of the medicine of above-mentioned treatment prolapse of lumbar intervertebral disc is: Radix Angelicae Pubescentis, Herba Taxilli, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, Caulis Piperis Kadsurae, Caulis Sargentodoxae, Ramulus Mori, Radix Clematidis, Radix Notoginseng, the Radix Astragali, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Caulis Spatholobi, Cortex Eucommiae(processed with salt), Radix Cyathulae, Radix Dipsaci, Rhizoma Drynariae, Rhizoma Cibotii, Herba Epimedii, Cortex Phellodendri and the Pachyrhizua angulatus mix homogeneously of getting formula ratio; Pulverize the Olibanum and the Myrrha mix homogeneously of back and formula ratio; Extract 2～3 times with 70～95% (v/v) alcohol heating reflux, extract 1～3h at every turn, filter; Merging filtrate; Add the Mentholum and the Borneolum Syntheticum of formula ratio, stir, process various preparation by existing conventional method then.
In the above-mentioned method for preparing, described pulverizing normally is crushed to 10～50 orders; Consumption of ethanol is preferably 2～6 times of raw material weight when each reflux, extract.
The method of medicine according to the invention being processed plaster specifically can be: get Radix Angelicae Pubescentis, Herba Taxilli, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, Caulis Piperis Kadsurae, Caulis Sargentodoxae, Ramulus Mori, Radix Clematidis, Radix Notoginseng, the Radix Astragali, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Caulis Spatholobi, Cortex Eucommiae(processed with salt), Radix Cyathulae, Radix Dipsaci, Rhizoma Drynariae, Rhizoma Cibotii, Herba Epimedii, Cortex Phellodendri and the Pachyrhizua angulatus mix homogeneously of formula ratio, pulverize the Olibanum and the Myrrha mix homogeneously of back and formula ratio, extract 2～3 times with 70～95% (v/v) alcohol heating reflux, extract 1～3h at every turn; Filter merging filtrate, filtrate recycling ethanol and to be condensed into 60 ℃ of following relative densities be 1.05～1.35 thick paste; Add the Mentholum and the Borneolum Syntheticum of formula ratio again, stir, add the substrate of 2～6 times of thick paste weight then; Stir, make and be coated with cream, will be coated with cream and evenly be coated with; Oven dry, cutting, lid lining; Punching, section promptly gets plaster.
In the method for preparing of above-mentioned plaster; Described substrate is made by conventional method by rubber, Colophonium, vaseline, lanoline and liquid paraffin, and wherein the weight ratio of rubber, Colophonium, zinc oxide, vaseline and lanoline specifically can be 6～7: 4～5: 6～7: 1: 1～2.
Compared with prior art, the present invention adopts the mutual compatibility of 20 multi-flavor medicines, Synergistic, and the effect of playing the liver and the kidney tonifying, dispelling cold and dehumidification, promoting flow of QI and blood, dredge the meridian passage altogether, good to the therapeutic effect of prolapse of lumbar intervertebral disc, have no side effect, relapse rate is extremely low.
Medicine according to the invention in sore spot and each subsides of left and right SHENYU acupoint place, pasted 6～12 hours when processing plaster every day.
The specific embodiment
With specific embodiment the present invention is described further below, but the present invention is not limited to these embodiment.
Embodiment 1
1) gets Radix Angelicae Pubescentis 160g, Herba Taxilli 120g, Radix Angelicae Dahuricae 160g, Rhizoma Chuanxiong 100g, Rhizoma Et Radix Notopterygii 120g, Caulis Piperis Kadsurae 120g, Caulis Sargentodoxae 30g, Ramulus Mori 30g, Radix Clematidis 30g, Radix Notoginseng 30g, Radix Astragali 30g, Radix Angelicae Sinensis 160g, Radix Paeoniae Alba 160g, Caulis Spatholobi 20g, Cortex Eucommiae(processed with salt) 20g, Radix Cyathulae 20g, Radix Dipsaci 120g, Rhizoma Drynariae 120g, Rhizoma Cibotii 120g, Herba Epimedii 30g, Cortex Phellodendri 20g and Pachyrhizua angulatus 20g mix homogeneously; Be crushed to behind 10 orders and Olibanum 20g and Myrrha 10g mix homogeneously; Extract 3 times with 70% (v/v) alcohol heating reflux and (add the ethanol extraction 2h of 6 times of raw material weights the 1st time; Add the ethanol extraction 2h of 4 times of raw material weights the 2nd time; Add the ethanol extraction 2h of 2 times of raw material weights the 3rd time); Filter merging filtrate, filtrate recycling ethanol and to be condensed into 60 ℃ of following relative densities be 1.35 thick paste; Add Mentholum 10g and Borneolum Syntheticum 150g and 1400 gram plaster stromas (by rubber, Colophonium, zinc oxide, vaseline and lanoline by 7: 5: 7: 1: 2 weight ratio makes with conventional method) again; Mix homogeneously prepares with conventional plaster method for preparing, promptly gets the plaster of treatment prolapse of lumbar intervertebral disc of the present invention.
Embodiment 2
1) gets Radix Angelicae Pubescentis 30g, Herba Taxilli 30g, Radix Angelicae Dahuricae 20g, Rhizoma Chuanxiong 20g, Rhizoma Et Radix Notopterygii 30g, Caulis Piperis Kadsurae 30g, Caulis Sargentodoxae 180g, Ramulus Mori 160g, Radix Clematidis 160g, Radix Notoginseng 100g, Radix Astragali 100g, Radix Angelicae Sinensis 30g, Radix Paeoniae Alba 30g, Caulis Spatholobi 160g, Cortex Eucommiae(processed with salt) 160g, Radix Cyathulae 160g, Radix Dipsaci 30g, Rhizoma Drynariae 30g, Rhizoma Cibotii 30g, Herba Epimedii 120g, Cortex Phellodendri 160g and Pachyrhizua angulatus 160g mix homogeneously; Be crushed to behind 50 orders and Olibanum 100g and Myrrha 10g mix homogeneously; Extract 2 times with 95% (v/v) alcohol heating reflux and (add the ethanol extraction 2h of 5 times of raw material weights the 1st time; Add the ethanol extraction 1h of 3 times of raw material weights the 2nd time); Filter; Merging filtrate; Filtrate recycling ethanol and to be condensed into 60 ℃ of following relative densities be 1.05 thick paste adds Mentholum 100g and Borneolum Syntheticum 20g and 1400 gram plaster stromas (by rubber, Colophonium, zinc oxide, vaseline and lanoline by 6: 4: 6: 1: 1 weight ratio makes with conventional method), mix homogeneously again; Plaster method for preparing with conventional prepares, and promptly gets the plaster of treatment prolapse of lumbar intervertebral disc of the present invention.
Embodiment 3
1) gets Radix Angelicae Pubescentis 60g, Herba Taxilli 100g, Radix Angelicae Dahuricae 50g, Rhizoma Chuanxiong 60g, Rhizoma Et Radix Notopterygii 60g, Caulis Piperis Kadsurae 60g, Caulis Sargentodoxae 60g, Ramulus Mori 100g, Radix Clematidis 60g, Radix Notoginseng 50g, Radix Astragali 60g, Radix Angelicae Sinensis 60g, Radix Paeoniae Alba 60g, Caulis Spatholobi 60g, Cortex Eucommiae(processed with salt) 70g, Radix Cyathulae 60g, Radix Dipsaci 60g, Rhizoma Drynariae 60g, Rhizoma Cibotii 60g, Herba Epimedii 70g, Cortex Phellodendri 60g and Pachyrhizua angulatus 60g mix homogeneously; Be crushed to behind 30 orders and Olibanum 30g and Myrrha 30g mix homogeneously; Extract 3 times with 90% (v/v) alcohol heating reflux and (add the ethanol extraction 1.5h of 4 times of raw material weights the 1st time; Add the ethanol extraction 1.5h of 3 times of raw material weights the 2nd time; Add the ethanol extraction 1h of 3 times of raw material weights the 3rd time); Filter merging filtrate, filtrate recycling ethanol and to be condensed into 60 ℃ of following relative densities be 1.20 thick paste; Add Mentholum 15g and Borneolum Syntheticum 70g and 1200 gram plaster stromas (by rubber, Colophonium, zinc oxide, vaseline and lanoline by 6.2: 4.5: 6.5: 1: 1.2 weight ratio makes with conventional method) again; Mix homogeneously prepares with conventional plaster method for preparing, promptly gets the plaster of treatment prolapse of lumbar intervertebral disc of the present invention.
Embodiment 4
1) gets Radix Angelicae Pubescentis 100g, Herba Taxilli 100g, Radix Angelicae Dahuricae 60g, Rhizoma Chuanxiong 60g, Rhizoma Et Radix Notopterygii 50g, Caulis Piperis Kadsurae 50g, Caulis Sargentodoxae 50g, Ramulus Mori 100g, Radix Clematidis 60g, Radix Notoginseng 50g, Radix Astragali 50g, Radix Angelicae Sinensis 50g, Radix Paeoniae Alba 50g, Caulis Spatholobi 50g, Cortex Eucommiae(processed with salt) 60g, Radix Cyathulae 50g, Radix Dipsaci 50g, Rhizoma Drynariae 50g, Rhizoma Cibotii 50g, Herba Epimedii 60g, Cortex Phellodendri 50g and Pachyrhizua angulatus 50g mix homogeneously; Be crushed to behind 20 orders and Olibanum 30g and Myrrha 50g mix homogeneously; Extract 3 times with 90% (v/v) alcohol heating reflux and (add the ethanol extraction 2h of 4 times of raw material weights the 1st time; Add the ethanol extraction 1.5h of 3 times of raw material weights the 2nd time; Add the ethanol extraction 1h of 3 times of raw material weights the 3rd time); Filter merging filtrate, filtrate recycling ethanol and to be condensed into 60 ℃ of following relative densities be 1.15 thick paste; Add Mentholum 30g and Borneolum Syntheticum 70g and 1300 gram plaster stromas (by rubber, Colophonium, vaseline, lanoline and liquid paraffin by 6.5: 4.3: 6.5: 1: 1.2 weight ratio makes with conventional method) again; Mix homogeneously prepares with conventional plaster method for preparing, promptly gets the plaster of treatment prolapse of lumbar intervertebral disc of the present invention.
Embodiment 5
1) gets Radix Angelicae Pubescentis 60g, Herba Taxilli 180g, Radix Angelicae Dahuricae 70g, Rhizoma Chuanxiong 120g, Rhizoma Et Radix Notopterygii 70g, Caulis Piperis Kadsurae 70g, Caulis Sargentodoxae 50g, Ramulus Mori 70g, Radix Clematidis 50g, Radix Notoginseng 50g, Radix Astragali 70g, Radix Angelicae Sinensis 120g, Radix Paeoniae Alba 70g, Caulis Spatholobi 70g, Cortex Eucommiae(processed with salt) 50g, Radix Cyathulae 70g, Radix Dipsaci 180g, Rhizoma Drynariae 180g, Rhizoma Cibotii 180g, Herba Epimedii 50g, Cortex Phellodendri 60g and Pachyrhizua angulatus 60g mix homogeneously; Be crushed to behind 40 orders and Olibanum 100g and Myrrha 20g mix homogeneously; Extract 3 times with 95% (v/v) alcohol heating reflux and (add the ethanol extraction 1.5h of 3 times of raw material weights the 1st time; Add the ethanol extraction 1.5h of 2 times of raw material weights the 2nd time; Add the ethanol extraction 1h of 2 times of raw material weights the 3rd time); Filter merging filtrate, filtrate recycling ethanol and to be condensed into 60 ℃ of following relative densities be 1.10 thick paste; Add Mentholum 50g and Borneolum Syntheticum 30g and 1600 gram plaster stromas (by rubber, Colophonium, zinc oxide, vaseline and lanoline by 6: 4: 6: 1: 1 weight ratio makes with conventional method) again; Mix homogeneously prepares with conventional plaster method for preparing, promptly gets the plaster of treatment prolapse of lumbar intervertebral disc of the present invention.
Experimental example 1
Gong, the man, 55 years old, once sprained waist when serving in the army, stay old complaint.Nineteen ninety-five CT examination to examine be the 4.5th prolapse of lumbar intervertebral disc (central type), often pain firmly appears in improper or waist because of position, limitation of activity, the nameless symptom such as numb of left lower extremity and left side foot.Cause disease to be sent out when work in August, 2006 because of position is improper, at that time pain unbearably, limitation of activity must be lain up after going home; The plaster of bringing into use the embodiment of the invention 1 to make on the 3rd day after sick the sending out in sore spot and each subsides of left and right SHENYU acupoint place, pasted 8 hours every day; Back lumbar part pain alleviated to some extent in 6 hours, can do the activity of standing up in bed, and medication is after 2 days; Can leave the bed and walk, stand the work of to go to work after 3 days.After the medication 30 days, lumbago disappears, activity freely, left lower extremity and the nameless numb disappearance of left side foot are felt good.Do not see anaphylaxiss such as red swelling of the skin, pruritus during the whole medication.
Experimental example 2
Jiang, the man, 38 years old, can not bend over because of lumbago for the end of the year 2005; And waist can not be exerted all one's strength, and both feet can not be squatted down, and nuclear magnetic resonance check is diagnosed as the 4th, 5 lumbar intervertebral disc, sacrum 1 outstanding disease; Shank outside distending pain at that time, pressuring nerve on sick leave 2 weeks, was once done massage; The traction physical therapy, DeGrain, still unable to walk (walking approximately 200 meters needs to have a rest once) far away.The plaster that bring into use the embodiment of the invention 2 to make in January, 2006; Pasted 6 hours every day in sore spot and each subsides of left and right SHENYU acupoint place; Medication is numb swelling disappearance after 21 days; During pasting, do not eat other medicines and do not treat yet, do not see any untoward reaction and side effect during the medication with other modes with this plaster treatment.Follow up a case by regular visits to not recurrence so far.
Experimental example 3
Prunus mume (sieb.) sieb.et zucc., the woman, 42 years old, began lumbago in June, 2006, once took the ibuprofen pain relieving, is diagnosed as prolapse of lumbar intervertebral disc through CT examination, after due to illness feelings influences be in and lie up, bed and can not oneself standing up.The plaster that bring into use the embodiment of the invention 3 to make in July, 2006 in sore spot and each subsides of left and right SHENYU acupoint place, pasted 12 hours every day, and medication can oneself be stood up after 2 hours, can leave the bed in the 2nd day, but normal activity after 7 days can normally be gone to work after 15 days.In therapeutic process, do not eat other medicines and do not treat yet, do not see any untoward reaction and side effect during the medication with other modes.So far not recurrence after the healing.
Experimental example 4
Beam, the man 62 years old, once sprained waist at an early age.It is the 4.5th prolapse of lumbar intervertebral disc (central type) that CT examination in 1991 is examined, and often pain, limitation of activity firmly appear in improper or waist because of position.Cause disease to be sent out because of position is improper during in May, 2004 work, at that time pain unbearably, limitation of activity need be lain up.The plaster of bringing into use the embodiment of the invention 2 to make in second day after sick the sending out in sore spot and each subsides of left and right SHENYU acupoint place, pasted 12 hours every day; Back lumbar part pain alleviated to some extent in 12 hours, can do the activity of standing up in bed, and medication is after 3 days; Can leave the bed and walk, stand the work of to go to work after 7 days.After the medication 30 days, lumbago disappears, and activity is felt good freely.Do not see anaphylaxiss such as red swelling of the skin, pruritus during the whole medication.
Experimental example 5
Lee, the woman, 51 years old, began lumbago in July, 2005, once did massage, the traction physical therapy is invalid, is diagnosed as prolapse of lumbar intervertebral disc through CT examination, after due to illness feelings influences be in and lie up, bed and can not oneself standing up.The plaster that bring into use the embodiment of the invention 5 to make in August, 2005 in sore spot and each subsides of left and right SHENYU acupoint place, pasted 8 hours every day, and medication can be left the bed on the 2nd day, and is freely movable after 14 days.In therapeutic process, do not eat other medicines and do not treat yet, do not see any untoward reaction and side effect during the medication with other modes.So far not recurrence after the healing.
Experimental example 6
What certain, the woman, 48 years old, begin lumbago the end of the year 2003, waist can not be exerted all one's strength, and left side lower limb radiating pain after CT examination is diagnosed as the 3.4th prolapse of lumbar intervertebral disc, was once done massage, and traction physical therapy, acupuncture are invalid, all only play the respite effect, still recurrence often.The plaster that bring into use the embodiment of the invention 3 to make in February, 2004, each one pastes in sore spot and left and right SHENYU acupoint place, pastes every day 12 hours, sb.'s illness took a favorable turn after 3 days in medication, medication after 7 days lumbago disappear, medication after 21 days activity freely, recurrence so far.Do not see any untoward reaction and side effect during the medication.
Claims (6)
1. medicine of treating prolapse of lumbar intervertebral disc is characterized in that it is processed by following materials of weight proportions:
Radix Angelicae Pubescentis 20～160 Herba Taxillis 30～180 Radixs Angelicae Dahuricae 20～160
Rhizoma Chuanxiong 20～160 Rhizoma Et Radix Notopterygiis 30～180 Caulis Piperis Kadsuraes 30～180
Caulis Sargentodoxae 30～180 Ramulus Moris 30～180 Radix Clematidis 30～180
Radix Notoginseng 30～100 Radixs Astragali 30～100 Radix Angelicae Sinensis 30～180
The Radix Paeoniae Alba 20～160 Caulis Spatholobis 20～160 Cortex Eucommiae(processed with salt) 20～160
Radix Cyathulae 20～160 Radix Dipsacis 30～180 Rhizoma Drynariae 30～180
Rhizoma Cibotii 30～180 Herba Epimedii 30～120 Cortex Phellodendris 20～160
Pachyrhizua angulatus 20～160 Olibanums 10～100 Myrrhas 10～100
Mentholum 10～100 Borneolum Syntheticums 20～160.
2. the medicine of treatment prolapse of lumbar intervertebral disc according to claim 1 is characterized in that: the weight proportion of said each raw material is:
Radix Angelicae Pubescentis 50～100 Herba Taxillis 60～120 Radixs Angelicae Dahuricae 50～100
Rhizoma Chuanxiong 60～120 Rhizoma Et Radix Notopterygiis 60～120 Caulis Piperis Kadsuraes 60～120
Caulis Sargentodoxae 30～150 Ramulus Moris 80～150 Radix Clematidis 50～100
Radix Notoginseng 50～100 Radixs Astragali 50～100 Radix Angelicae Sinensis 60～120
The Radix Paeoniae Alba 50～100 Caulis Spatholobis 60～120 Cortex Eucommiae(processed with salt) 60～120
Radix Cyathulae 30～80 Radix Dipsacis 30～80 Rhizoma Drynariae 30～80
Rhizoma Cibotii 30～80 Herba Epimedii 60～100 Cortex Phellodendris 50～100
Pachyrhizua angulatus 50～100 Olibanums 10～60 Myrrhas 10～60
Mentholum 10～40 Borneolum Syntheticums 50～120.
3. the medicine of treatment prolapse of lumbar intervertebral disc according to claim 1 and 2 is characterized in that: the dosage form of this medicine is a plaster.
4. the method for preparing of the medicine of the described treatment prolapse of lumbar intervertebral disc of claim 1; It is characterized in that: get Radix Angelicae Pubescentis, Herba Taxilli, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, Caulis Piperis Kadsurae, Caulis Sargentodoxae, Ramulus Mori, Radix Clematidis, Radix Notoginseng, the Radix Astragali, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Caulis Spatholobi, Cortex Eucommiae(processed with salt), Radix Cyathulae, Radix Dipsaci, Rhizoma Drynariae, Rhizoma Cibotii, Herba Epimedii, Cortex Phellodendri and the Pachyrhizua angulatus mix homogeneously of formula ratio, pulverize the Olibanum and the Myrrha mix homogeneously of back and formula ratio, extract 2～3 times with 70～95% (v/v) alcohol heating reflux; Each 1～3h that extracts; Filter merging filtrate, the Mentholum and the Borneolum Syntheticum of adding formula ratio; Stir, process various preparation by existing conventional method.
5. the method for preparing of the medicine of treatment prolapse of lumbar intervertebral disc according to claim 4 is characterized in that: get Radix Angelicae Pubescentis, Herba Taxilli, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, Caulis Piperis Kadsurae, Caulis Sargentodoxae, Ramulus Mori, Radix Clematidis, Radix Notoginseng, the Radix Astragali, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Caulis Spatholobi, Cortex Eucommiae(processed with salt), Radix Cyathulae, Radix Dipsaci, Rhizoma Drynariae, Rhizoma Cibotii, Herba Epimedii, Cortex Phellodendri and the Pachyrhizua angulatus mix homogeneously of formula ratio, pulverize the Olibanum and the Myrrha mix homogeneously of back and formula ratio; Extract 2～3 times with 70～95% (v/v) alcohol heating reflux, extract 1～3h at every turn, filter; Merging filtrate, filtrate recycling ethanol and to be condensed into 60 ℃ of following relative densities be 1.05～1.35 thick paste adds the substrate of 2～6 times of raw material weights then; Stir, add the Mentholum and the Borneolum Syntheticum of formula ratio again, stir; Make and be coated with cream, will be coated with cream and evenly be coated with, oven dry; Cutting, lid lining, punching; Section promptly gets plaster.
6. the method for preparing of the medicine of treatment prolapse of lumbar intervertebral disc according to claim 5 is characterized in that: consumption of ethanol is 2～6 times of raw material weight during each reflux, extract.
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| CN103110817A (en) * | 2013-03-13 | 2013-05-22 | 董玲悦 | Traditional Chinese medicine for treating diseases caused by spinal lesions |
| CN103463261A (en) * | 2013-09-04 | 2013-12-25 | 杜应存 | Traditional Chinese medicine preparation for treating lumbar intervertebral disc herniation |
| CN103585299A (en) * | 2013-11-27 | 2014-02-19 | 葛才志 | Medicine for treating disc protrusion and bulge of lumbar vertebra and cervical vertebra |
| CN103989877A (en) * | 2014-05-28 | 2014-08-20 | 孙刚 | Traditional Chinese medicinal preparation for treating protrusion of lumbar intervertebral disc and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559486A (en) * | 2004-02-28 | 2005-01-05 | 郭永昌 | Health-care medicinal plaster used for preventing and curing discopathy, osteosis, ischialgia |
| CN101085304A (en) * | 2007-06-18 | 2007-12-12 | 付先进 | Plaster mainly for curing cervical vertebra and lumbar vertebra disease |
| CN101461879A (en) * | 2008-05-16 | 2009-06-24 | 胡元广 | Plaster for treating neck, spine, protrusion of lumbar vertebral disc, hyperosteogeny, arthralgia and myalgia |
| CN102283921A (en) * | 2011-09-08 | 2011-12-21 | 鲍修惠 | Prescription drug for curing jugular and lumbar herniated disk |
-
2012
- 2012-03-22 CN CN 201210078066 patent/CN102579652B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559486A (en) * | 2004-02-28 | 2005-01-05 | 郭永昌 | Health-care medicinal plaster used for preventing and curing discopathy, osteosis, ischialgia |
| CN101085304A (en) * | 2007-06-18 | 2007-12-12 | 付先进 | Plaster mainly for curing cervical vertebra and lumbar vertebra disease |
| CN101461879A (en) * | 2008-05-16 | 2009-06-24 | 胡元广 | Plaster for treating neck, spine, protrusion of lumbar vertebral disc, hyperosteogeny, arthralgia and myalgia |
| CN102283921A (en) * | 2011-09-08 | 2011-12-21 | 鲍修惠 | Prescription drug for curing jugular and lumbar herniated disk |
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| CN103110817A (en) * | 2013-03-13 | 2013-05-22 | 董玲悦 | Traditional Chinese medicine for treating diseases caused by spinal lesions |
| CN103463261A (en) * | 2013-09-04 | 2013-12-25 | 杜应存 | Traditional Chinese medicine preparation for treating lumbar intervertebral disc herniation |
| CN103463261B (en) * | 2013-09-04 | 2015-06-03 | 杜应存 | Traditional Chinese medicine preparation for treating lumbar intervertebral disc herniation |
| CN103585299A (en) * | 2013-11-27 | 2014-02-19 | 葛才志 | Medicine for treating disc protrusion and bulge of lumbar vertebra and cervical vertebra |
| CN103585299B (en) * | 2013-11-27 | 2015-04-15 | 济南宏坤大药房 | Medicine for treating disc protrusion and bulge of lumbar vertebra and cervical vertebra |
| CN103989877A (en) * | 2014-05-28 | 2014-08-20 | 孙刚 | Traditional Chinese medicinal preparation for treating protrusion of lumbar intervertebral disc and preparation method thereof |
| CN104306570A (en) * | 2014-09-28 | 2015-01-28 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicinal preparation for treating lumbar disc herniation and preparation method thereof |
| CN104383437A (en) * | 2014-11-04 | 2015-03-04 | 刘子令 | Medicine for treating arthralgia and myalgia and preparation method thereof |
| CN105213601A (en) * | 2015-09-30 | 2016-01-06 | 陈玉勇 | A kind of medicine and preparation method thereof for the treatment of hyperosteogeny, prolapse of lumbar intervertebral disc |
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| CN105596513A (en) * | 2016-02-05 | 2016-05-25 | 柳州市妇幼保健院 | Traditional Chinese medicine preparation for treating lumbar disc herniation |
| CN105998226A (en) * | 2016-06-16 | 2016-10-12 | 浙江中医药大学 | Preparation method for traditional Chinese medicine granules for treating osteoarthritis |
| CN108669270A (en) * | 2018-05-25 | 2018-10-19 | 梧州学院 | A kind of parasitism tea granule composition and preparation method thereof |
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| CN115025187A (en) * | 2022-08-11 | 2022-09-09 | 江西中医药大学附属医院 | Traditional Chinese medicine composition for treating lumbago, acupoint plaster and preparation method and application thereof |
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