CN102308988B - Dendrobium health product having function of human body immunization enhancement - Google Patents
Dendrobium health product having function of human body immunization enhancement Download PDFInfo
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Abstract
The invention relates to the field of health products. A technical scheme adopted in the invention is to provide a dendrobium health product having the function of human body immunization enhancement. The health product is prepared from the following raw materials, by weight, 21-56% of Dendrobium officinale Kimura et Migo, 23-48% of pseudo-ginseng, and 20-50% of Radix Puerariae. A preparation method of the health product comprises the following steps: 1, obtaining Dendrobium powder by ultramicro crushing Dendrobium officinale Kimura et Migo; 2, obtaining pseudo-ginseng powder by ultramicro crushing pseudo-ginseng; 3, extracting puerarin from Radix Puerariae with a macroporous adsorption resin process; and 4, obtaining loose powder by uniformly mixing the Dendrobium powder, the pseudo-ginseng powder and Radix Puerariae powder. The health product is a health product preparation, and all effective components of the preparation are Chinese herbal medicines, so the preparation of the present invention has the effects of yin nourishing, human body immunization capability enhancement, blood circulation promotion and blood stasis removal, "three high symptoms" prevention, human body hormone enhancement, and enhancement of the youthful vitality of human bodies.
Description
Technical field
The present invention relates to field of health care products, relate in particular to a kind of dendrobium health-care product that strengthens immune function of human body that has.
Background technology
Along with growth in the living standard and social competition's pressure, diet is unreasonable.It is not enough to have a rest, and does not particularly have enough sleep, daily life is irregular, the undesired common phenomenon that become of work and rest.Overstretched, pressure is too large.IT white collar personage particularly, body kinematics is not enough, the muscle power overdraw.Permanent unhealthy emotion impacts etc. increase day by day so that be in the crowd of inferior health, and resistance descends, and has increased the invasion of various germs, affects routine work.
Change along with growth in the living standard and rhythm of life, " three high diseases " (being hypertension, hyperglycaemia and high fat of blood) that is called as " rich man's disease ", such as " the old times king thanks to a front swallow; fly into common people house ", healthy common diseases of the elderly more than 50 years old particularly, every year is died from the number of cardiovascular and cerebrovascular disease up to 1,500 ten thousand people in the whole world, and it is the first to occupy the various causes of the death.Cardiovascular and cerebrovascular disease has become human Death causes the highest " No.1 killer ", also be " the noiseless demon " of health of people, cardiovascular and cerebrovascular disease has the characteristics of " incidence of disease is high, disability rate is high, the death rate is high, recurrence rate is high; complication is many " formation " four is high by more than one ", at present, China's Patients with Cardiovascular/Cerebrovascular Diseases has surpassed 2.7 hundred million people.
Immunity is the defense mechanism of human body self, is human body identification and any foreign matter (virus, bacterium etc.) of eliminating external intrusion; Process the ability of self cell and identification and processing vivo mutations cell and the virus infected cell of old and feeble, damage, dead, sex change.The immunity of human body depends on gene mostly, but the impact of environment is also very large, such as diet, sleep, motion, pressure etc.Wherein diet has conclusive influence power, because the composition of some food can be assisted stimulating immune system, strengthens immunocompetence.If lack these important nutrient compositions, can have a strong impact on the immune system function of health.
Hormone (hormone) comes from Greek, is exactly hormone, and the meaning is " activation ", is the general name of the hormone that can regulate physiological equilibrium of human endocrine system secretion.Various hormone are constant to environment in the human body metabolism, the coordination between the organ and grow, reproduction etc. plays regulating action.It not only affects a normal person's growth, growth and mood performance, keeps especially the key factor of the balanced action of each tract in the body, and it is in a single day unbalance, and health just pathology can occur.Whether a people can reach dedicate one's life to heart health, and hormone is taken on very important status.
Summary of the invention
The purpose of this invention is to provide a kind of dendrobium health-care product that strengthens immune function of human body that has.
The technical solution used in the present invention is: a kind of dendrobium health-care product with enhancing immune function of human body, made by the raw material of following weight proportion: dendrobium candidum 21～56%, pseudo-ginseng 23～48%, the root of kudzu vine 20～50%; Its preparation method is as follows:
(1) dendrobium candidum adopts the ultramicro grinding method to obtain stem of noble dendrobium fecula: get dendrobium candidum and pulverize as being 4～32 order powder to fineness of powder, under-17～0 ℃ low temperature, use supersonic jet mill afterwards, obtaining fineness of powder is 200～1250 purpose powder, is stem of noble dendrobium fecula;
(2) pseudo-ginseng obtains the pseudo-ginseng fecula with the ultramicro grinding method: pseudo-ginseng is crushed to fineness of powder first in medicinal herb grinder be 4～32 order powder, under-17～0 ℃ low temperature, use supersonic jet mill afterwards, obtaining fineness of powder is 500～1250 purpose Ultramicro-powders, is the pseudo-ginseng fecula;
(3) root of kudzu vine adopts Flavonoids by Macroporous Adsorption Resin to extract Puerarin: after getting root of kudzu vine pulverizing medicinal materials to fineness of powder and being 20～40 order powder, the ethanolic solution (concentration of alcohol is 40～90%) that adds 4～8 times of volumes of root of kudzu vine powder extracts 2～5 times, each 0.5～1.5h, with the concentrated upper large pore resin absorption column of extract, wash impurity with water, use again 30～70% ethanol elution, collect ethanol eluate, after concentrated, add ethanol and make determining alcohol reach 70～80%, the elimination sediment, filtrate is concentrated, add extracting n-butyl alcohol, reclaim n-butanol, concentrated, the dry Puerarin that gets;
(4) dendrobium polysaccharide, pseudo-ginseng fecula and the Puerarin of gained mixed obtain loose powder.
A kind of dendrobium health-care product with enhancing immune function of human body is characterized in that being made by the raw material of following weight proportion: dendrobium candidum 26～48%, pseudo-ginseng 26～43%, the root of kudzu vine 25～45%.
Described macroreticular resin is AB-8, D-101, HPD100 type.
Described loose powder is prepared into tablet, hard shell capsules or soft capsule according to the conventional technology of preparing of Chinese medicine.
The present invention is health-care preparation, and the effective ingredient of preparation all is Chinese herbal medicine, and the component compatibility is reasonable, and the effect of each Chinese medicine of distinguishing the flavor of is as follows:
Dendrobium candidum: Dendrobii Officinalis Caulis, this product is the dry stem of orchid dendrobium candidum Dendrobium officinale Kimura et Migo.Be a yin tonics commonly used, have reinforcing stomach reg fluid, nourishing Yin and clearing heat function is used for pyreticosis Tianjin and hinders, the dry polydipsia, and deficiency of stomach-Yin, food is few retches, and abnormal heat is not moved back after being ill, and is fire excess from yin deficiency, hectic fever due to yin labor heat, order is secretly not clear, and the muscles and bones impotence is soft.(pharmacopeia 2010)
Pseudo-ginseng: Radix et Rhizoma notoginseng this product is the dry root and rhizome of panax araliaceae plant Panax notoginseng (Burk.) F.H.Chen.Function cures mainly loose stasis of blood hemostasis, detumescence ding-tong.Be used for spitting of blood, spit blood, bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, and traumatism and bleeding, the chest abdomen twinges, tumbling and swelling.(pharmacopeia 2005 [Dans)
The root of kudzu vine: Puerariae Lobatae Radix, this Lu are the dry root of legume pueraria lobata Pueraria Iobata (Willd) Ohwi.Function cures mainly relieving muscles to expel heat, promotes the production of body fluid to quench thirst, and promoting eruption rises positive antidiarrheal, and is clearing and activating the channels and collaterals, relieving alcoholism.Be used for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hot dysentery is had loose bowels, dizziness and headache, hemiplegia, chest impediment and cardialgia is during the wine poison is hindered.
Beneficial effect of the present invention
Dendrobium candidum mainly contains the compositions such as polysaccharide, alkaloid, trace element and amino acid, and wherein the polysaccharide composition has the active component of immunological enhancement and antitumor action.Ultramicro grinding keeps active ingredient and can reach more than 90%, and it is low to have a cost, and yield is high, embodies that the stem of noble dendrobium is many-sided to be worth.
Pseudo-ginseng contains 21 kinds of saponin active materials, 17 seed amino acids, 11 kinds of trace elements, three kinds of active anticancer selenium and thick protein etc.The main component that pseudo-ginseng affects immunologic function is PNS and notoginseng polysaccharide, has the effect of immunomodulator, and too high or too low immune response is returned to normally, but the not normal immune response of interference body.The present invention adopts low temperature ultramicro grinding method to obtain the pseudo-ginseng fecula, in crushing process, do not produce the hot-spot phenomenon, speed is fast, moment can finish, obtain Ultramicro-powder, broken the cell membrane of pseudo-ginseng, pseudo-ginseng is existed with the form of minuteness particle group, each particle cluster comprises the various compositions of same ratio; Increase the specific area of pseudo-ginseng powder, promoted stripping, improved drug effect; The bioactive ingredients that keeps to greatest extent powder is conducive to make required high quality of products.
The root of kudzu vine contains abundant Puerarin, this glucoside of Xun Gensu, isoflavones, daidzein, ammonia pours acid, trace element, triterpene substance alkali etc. to human body beneficial's important biomolecule active material, energy balance the body function, build up health, improve body resistance against diseases, anti-ageing prolonging life, the vigor of remaining youthful forever.Its main component of the root of kudzu vine is starch, contains in addition 12% the flavone compound of having an appointment, and comprises that soybean (soya bean) glucoside, daidzein, Puerarin etc. more than 10 plant, so the present invention adopts Flavonoids by Macroporous Adsorption Resin to extract Puerarin, the little starch removal of effect.
A kind of dendrobium health-care product with enhancing immune function of human body of the present invention has yin-nourishing, strengthens human immunological competence's effect, is applicable to the sub-health population of hypoimmunity.
The present invention is a kind of to have the dendrobium health-care product that strengthens immune function of human body, has promoting blood circulation and removing blood stasisly, has the effect of good prevention " three high diseases ".
A kind of dendrobium health-care product with enhancing immune function of human body has the human body of raising hormone, strengthens the youthful vigor of human body.
Specific embodiment
Embodiment 1
A kind of dendrobium health-care product with enhancing immune function of human body is made by the raw material of following weight proportion: dendrobium candidum 21%, pseudo-ginseng 29%, the root of kudzu vine 50%; Its preparation method is as follows:
(1) dendrobium candidum adopts the ultramicro grinding method to obtain stem of noble dendrobium fecula: get dendrobium candidum and pulverize as being 4 order powder to fineness of powder, use supersonic jet mill afterwards under 0 ℃ low temperature, obtaining fineness of powder is 200 purpose powder, is stem of noble dendrobium fecula;
(2) pseudo-ginseng obtains the pseudo-ginseng fecula with the ultramicro grinding method: pseudo-ginseng is crushed to fineness of powder first in medicinal herb grinder be 4 order powder, uses supersonic jet mill afterwards under 0 ℃ low temperature, and obtaining fineness of powder is 500 purpose Ultramicro-powders, is the pseudo-ginseng fecula;
(3) root of kudzu vine adopts Flavonoids by Macroporous Adsorption Resin to extract Puerarin: after getting root of kudzu vine pulverizing medicinal materials to fineness of powder and being 20 order powder, the ethanolic solution that adds 4 times of volumes 40% of root of kudzu vine powder extracts 2 times, each 0.5h, with the concentrated upper AB-8 type large pore resin absorption column of extract, wash impurity with water, use again 30% ethanol elution, collect ethanol eluate, after concentrated, add ethanol and make determining alcohol reach 70%, the elimination sediment, filtrate is concentrated, add extracting n-butyl alcohol, reclaim n-butanol, concentrated, the dry Puerarin that gets;
(4) stem of noble dendrobium fecula, pseudo-ginseng fecula and the kudzu-vine root powder of gained mixed obtain loose powder;
(5) above-mentioned loose powder is become tablet, obtain tablet of the present invention.
Embodiment 2
A kind of dendrobium health-care product with enhancing immune function of human body is made by the raw material of following weight proportion: dendrobium candidum 35%, pseudo-ginseng 35%, the root of kudzu vine 30%; Its preparation method is as follows:
(1) dendrobium candidum adopts the ultramicro grinding method to obtain stem of noble dendrobium fecula: get dendrobium candidum and pulverize as being 20 order powder to fineness of powder, use supersonic jet mill afterwards under-9 ℃ low temperature, obtaining fineness of powder is 700 purpose powder, is stem of noble dendrobium fecula;
(2) pseudo-ginseng obtains the pseudo-ginseng fecula with the ultramicro grinding method: pseudo-ginseng is crushed to fineness of powder first in medicinal herb grinder be 20 order powder, uses supersonic jet mill afterwards under-9 ℃ low temperature, and obtaining fineness of powder is 900 purpose Ultramicro-powders, is the pseudo-ginseng fecula;
(3) root of kudzu vine adopts Flavonoids by Macroporous Adsorption Resin to extract Puerarin: after getting root of kudzu vine pulverizing medicinal materials to fineness of powder and being 30 order powder, the ethanolic solution that adds 6 times of volumes 60% of root of kudzu vine powder extracts 3 times, each 1h, with the concentrated upper D-101 type large pore resin absorption column of extract, wash impurity with water, use again 50% ethanol elution, collect ethanol eluate, after concentrated, add ethanol and make determining alcohol reach 75%, the elimination sediment, filtrate is concentrated, add extracting n-butyl alcohol, reclaim n-butanol, concentrated, the dry Puerarin that gets;
(4) stem of noble dendrobium fecula, pseudo-ginseng fecula and the kudzu-vine root powder of gained mixed obtain loose powder;
(5) above-mentioned loose powder is become hard shell capsules, obtain hard capsule of the present invention.
Embodiment 3
A kind of dendrobium health-care product with enhancing immune function of human body is made by the raw material of following weight proportion: dendrobium candidum 56%, pseudo-ginseng 23%, the root of kudzu vine 21%; Its preparation method is as follows:
(1) dendrobium candidum adopts the ultramicro grinding method to obtain stem of noble dendrobium fecula: get dendrobium candidum and pulverize as being 32 order powder to fineness of powder, use supersonic jet mill afterwards under-17 ℃ low temperature, obtaining fineness of powder is 1250 purpose powder, is stem of noble dendrobium fecula;
(2) pseudo-ginseng obtains the pseudo-ginseng fecula with the ultramicro grinding method: pseudo-ginseng is crushed to fineness of powder first in medicinal herb grinder be 32 order powder, under-17 ℃ low temperature, use supersonic jet mill afterwards, obtaining fineness of powder is 1250 purpose Ultramicro-powders, is the pseudo-ginseng fecula;
(3) root of kudzu vine adopts Flavonoids by Macroporous Adsorption Resin to extract Puerarin: after getting root of kudzu vine pulverizing medicinal materials to fineness of powder and being 40 order powder, the ethanolic solution that adds 8 times of volumes 90% of root of kudzu vine powder extracts 5 times, each 1.5h, with the concentrated upper HPD100 type large pore resin absorption column of extract, wash impurity with water, use again 70% ethanol elution, collect ethanol eluate, after concentrated, add ethanol and make determining alcohol reach 80%, the elimination sediment, filtrate is concentrated, add extracting n-butyl alcohol, reclaim n-butanol, concentrated, the dry Puerarin that gets;
(4) stem of noble dendrobium fecula, pseudo-ginseng fecula and the kudzu-vine root powder of gained mixed obtain loose powder;
(5) above-mentioned loose powder is become soft capsule, obtain soft capsule of the present invention.
Claims (4)
1. one kind has the dendrobium health-care product that strengthens immune function of human body, and it is characterized in that: the raw material by following weight proportion is made: dendrobium candidum 21～56%, pseudo-ginseng 23～48%, and the root of kudzu vine 20～50%, wherein dendrobium candidum is the dry stem of orchid dendrobium candidum; Its preparation method is as follows:
(1) dendrobium candidum adopts the ultramicro grinding method to obtain stem of noble dendrobium fecula: getting dendrobium candidum, to be crushed to fineness of powder be 4～32 order powder, under-17～0 ℃ low temperature, use supersonic jet mill afterwards, obtaining fineness of powder is 200～1250 purpose powder, is stem of noble dendrobium fecula;
(2) pseudo-ginseng obtains the pseudo-ginseng fecula with the ultramicro grinding method: pseudo-ginseng is crushed to fineness of powder first in medicinal herb grinder be 4～32 order powder, under-17～0 ℃ low temperature, use supersonic jet mill afterwards, obtaining fineness of powder is 500～1250 purpose Ultramicro-powders, is the pseudo-ginseng fecula;
(3) root of kudzu vine adopts Flavonoids by Macroporous Adsorption Resin to extract Puerarin: after getting root of kudzu vine pulverizing medicinal materials to fineness of powder and being 20～40 order powder, adding 4～8 times of volume concentration of root of kudzu vine powder and be 40～90% ethanolic solution extracts 2～5 times, each 0.5～1.5h, with the concentrated upper large pore resin absorption column of extract, wash impurity with water, be 30～70% ethanol elution again with concentration, collect ethanol eluate, after concentrated, add ethanol and make determining alcohol reach 70～80%, the elimination sediment, filtrate is concentrated, add extracting n-butyl alcohol, reclaim n-butanol, concentrated, the dry Puerarin that gets;
(4) stem of noble dendrobium fecula, pseudo-ginseng fecula and the Puerarin of gained mixed obtain loose powder.
2. a kind of dendrobium health-care product that strengthens immune function of human body that has according to claim 1 is characterized in that being made by the raw material of following weight proportion: dendrobium candidum 26～48%, pseudo-ginseng 26～43%, the root of kudzu vine 25～45%.
3. a kind of dendrobium health-care product that strengthens immune function of human body that has according to claim 1 and 2, it is characterized in that: described macroreticular resin is AB-8, D-101, HPD100 type.
4. a kind of dendrobium health-care product that strengthens immune function of human body that has according to claim 1 and 2, it is characterized in that: described loose powder is prepared into tablet, hard shell capsules or soft capsule according to the conventional technology of preparing of Chinese medicine.
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| CN106560201A (en) * | 2015-10-04 | 2017-04-12 | 浙江佳诚生物工程有限公司 | Recipe for novel Dendrobium officinale product capable of promoting blood circulation |
| CN105497559A (en) * | 2015-12-17 | 2016-04-20 | 刘爱华 | Pharmaceutical composition with blood glucose lowering function |
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| CN115040525A (en) * | 2022-06-23 | 2022-09-13 | 台州美艺添医疗科技有限公司 | Slimming fat solution and preparation method thereof |
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