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CN108310273A - A kind of external-applied ointment - Google Patents

A kind of external-applied ointment Download PDF

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Publication number
CN108310273A
CN108310273A CN201810420184.5A CN201810420184A CN108310273A CN 108310273 A CN108310273 A CN 108310273A CN 201810420184 A CN201810420184 A CN 201810420184A CN 108310273 A CN108310273 A CN 108310273A
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China
Prior art keywords
parts
external
chinese medicine
medicine material
applied ointment
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CN201810420184.5A
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Chinese (zh)
Inventor
胡映奇
胡安佳
胡安强
胡安智
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/02Ammonia; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of external-applied ointments, include the Chinese medicine material of following weight parts:38 parts of Lu sand, 38 parts of brush-cherry seed, 25 parts of peach kernel, 25 parts of almond, 25 parts of coix seed, 25 parts of Semen Ricini;When preparation, it is uniformly mixed after above-mentioned Chinese medicine material is crushed to 80 100 mesh, paste is adjusted to white wine, preserved under room temperature air-proof condition;The external-applied ointment of the present invention is made of natural Chinese traditional medicines raw material, is coated in the position of morbidity, and therapy is simple, clinical application safety, it is significant in efficacy, mitigate the pain of patient, can be used for treating wart, birthmark, hemangioma, lipoma, syringocystadenoma, freckle, mole and corn.

Description

A kind of external-applied ointment
Technical field
The present invention relates to pharmaceutical technology field, specifically a kind of external-applied ointment.
Background technology
Wart is by human papilloma virus(HPV)Caused epidermis benign neoplasm, wart can be by directly or indirectly connecing It touches and propagates, wound or skin injury are also an important factor to HPV infection, and the course of disease and the immunity of organism of wart have important pass System.Verruca vulgaris, plantar wart, flat wart and condyloma acuminatum etc. are clinically common are, the wart of specific type there are two classes:(1)Verruca filiformis: It is apt to occur in eyelid, neck, chin portion etc., mostly single soft filiform is prominent;(2)Digitate warts:On the basis of same soft The irregular multiple digitations of cluster occur, tip is cutin sample quil, and more or less for number, and often hair also may be used in scalp It sends out between face, toe.
Birthmark generally can be divided into pigment type and vascular type, and common pigment type includes nevus of Ota, congenital mole, coffee Spot etc.;Vascular type includes then nevus flammeus, strawberry hemangioma etc..Birthmark can be found at birth, it is also possible to several being born Just gradually morbidity after a month.
Hemangioma be by angioblast hyperplasia during embryo and being common in for being formed is congenital in skin and soft tissue Benign tumour or vascular malformation, when being more common in baby due or after birth soon.Remaining embryo angioblast, active is interior Skin sample plumule is invaded to adjacent tissue, is formed endothelium batten rope, is connected with left blood vessel through Guan Huahou and forms hemangioma, Blood vessel self-organizing system in tumor, is not connected with peripheral vessels.Hemangioma can betide whole body everywhere, betide the blood of oromaxillo-facial region Tuberculation accounts for the 60% of system vascular tumor, followed by trunk(25%)And four limbs(15%).It is wherein most of to betide facial skin, skin Undertissue and mucous membrane of mouth, such as tongue, lip, mouth bottom tissue, minority betides in jawbone or deep tissue.
Lipoma is a kind of common benign tumour, can betide any position for having fat.Some cases are happened at four Limb, mainly subcutaneous, also seen between limbs deep and belly of muscle.Deep lipoma mostly along muscle growth, can as deep as periosteum, but Seldom invade adjacent bones.The basic reason that lipoma is formed is since " the lipoma tumorigenesis factor " exists in patient's body cell A kind of tumorigenesis factor, under normal circumstances, this tumorigenesis factor are in a kind of inactivated state(Inactive state), but various interior Under the inducement influence of external environment, this lipoma tumorigenesis factor is in active state, has certain activity, is supported in body When drag declines, the immunocytes such as lymphocyte, mononuclear phagocytic cells in body decline the monitoring capacity of the tumorigenesis factor, then In addition internal interior environment changes, and under the conditions of the inducements such as chronic inflammation stimulation, body fat metabolic disorder, the lipoma tumorigenesis factor Activity further enhances certain genetic fragments in the normal cell with body and is combined, and forms gene unconventionality mutation, makes normal-fat A kind of paraplasm phenomenon occurs for cell and surrounding tissue cells, causes adipose tissue deposition related, and to body surface or it is each in Internal organs official lump outstanding, i.e. lipoma.
Syringocystadenoma is a kind of adenoma of eccrine gland conduit in epidermis, and Histochemical studies prove that syringocystadenoma contains typical eccrine gland The phosphorylase and hydrolase of origin are a kind of sweat gland benign tumours of terminad sweat duct differentiation.It is apt to occur in eyelid, cheek, neck The positions such as side, chest are also found in waist, the back of the body, four limbs and genitals etc..It to be showed based on hard tough small papule.Seldom voluntarily Subside, but not canceration.
Freckle is the dotted pigmentation spots of yellowish-brown occurred on skin of face, is autosomal dominant inheritance.Freckle female Property it is more, numbers with age increase and gradually increase.It is apt to occur in face, especially nose and two cheeks, neck, shoulder, hand can be involved The exposure portions such as the back of the body, non-exposed position is without fash.Damage is shallow brown or crineous syringe needle size to the big macula of mung bean, round, ovum It is round or irregular.It is dispersed in or cluster is distributed, it is isolated not merge.No conscious sympton.Summer fash color burn, number after solarization Mesh increases, and winter then mitigates or disappears, and often has family history.
Mole is medically referred to as mole cell or melanocytic nevus, is skin caused by epidermis, intradermal melanocytosis Performance.If it is fash that is surface, dome or nipple sample appearance or having the base of a fruit is higher by, clinically it is called intradermal nevus;Slightly Be higher by surface is mostly compound nevus;Be not higher by surface is junctional nevus.Mole have it is geneogenous, have the day after tomorrow formed, on human body 99 percent is all benign nevus, some moles are also possible to that lesion occurs.
Corn is pedal skin part long-term be pressurized and rub caused limitation, coniform hyperkeratosis, is commonly called as " meat Thorn ".The permanent people for standing and walking is easier to occur, and friction and compressing are main inducings.
Currently, hospital is using western medicine for wart, birthmark, freckle, mole and corn add drug therapy using laser, and Hemangioma, lipoma, syringocystadenoma are using the method for operation mostly, and since endo-medicine toxic side effect is big, the course for the treatment of is long, curative effect Slowly, the shortcomings of easy to recur, and expenses of surgical treatment is expensive.Therefore, research and develop a kind of external-applied ointment, can be used to treat simultaneously wart, Birthmark, hemangioma, lipoma, syringocystadenoma, freckle, mole and corn are the important contents that the present invention studies.
Invention content
The purpose of the present invention is aiming at traditional treatment wart, birthmark, hemangioma, lipoma, syringocystadenoma, mole, freckle and chicken The above problem existing for the method for eye, provides a kind of external-applied ointment, the present invention can cure wart, birthmark, hemangioma, fat simultaneously Tumor, syringocystadenoma, mole, freckle and corn, clinical application safety, significant in efficacy, external application does not stimulate internal organ, while effectively preventing curing Source sexuality dye, has no toxic side effect.
A kind of external-applied ointment of the present invention, includes the Chinese medicine material of following weight parts:
3-8 parts of brush-cherry seed of 3-8 parts of Lu sand
2-5 parts of almond of 2-5 parts of peach kernel
2-5 parts of Semen Ricini of 2-5 parts of coix seed;
When preparation, it is uniformly mixed after above-mentioned Chinese medicine material is crushed to 80-100 mesh, paste is adjusted to white wine, in room temperature sealing strip It is preserved under part.
Preferably, the present invention includes the Chinese medicine material of following weight parts:
4-6 parts of brush-cherry seed of 4-6 parts of Lu sand
2-4 parts of almond of 2-4 parts of peach kernel
2-4 parts of Semen Ricini of 2-4 parts of coix seed.
Further, the weight part ratio of each Chinese medicine material is in the present invention:
6 parts of Lu sand, 5 parts of brush-cherry seed
2 parts of peach kernel, 3 parts of almond
2 parts of coix seed, 3 parts of Semen Ricini.
Further, the weight part ratio of each Chinese medicine material is in the present invention:
8 parts of Lu sand, 8 parts of brush-cherry seed
4 parts of peach kernel, 4 parts of almond
4 parts of coix seed, 4 parts of Semen Ricini.
Preferably, the white wine that the white wine is 50 °.
Lu sand in we, taste is salty, bitter, pungent, warm, is mainly used for disperse accumulation softening hard masses, and drastically removing blood stasis and resolving static blood controls abdominal mass Xuan addictions, dysphagic Gastric disorder causing nausea, phlegm and retained fluid, larynx numbness, product dysentery, Amenorrhea, mesh screen, polyp, wart, furunculosis, scrofula, carbuncle swells, malignant sore.Brush-cherry seed in we It is flat, it is bitter, sweet, there is the effect of moistening lung laxation, lower gas profit water, qi stagnation of large intestine can be treated, dry puckery obstructed, difficult urination, big ascites It is swollen, four limbs edema, the symptoms such as tinea pedis.Peach kernel bitter but sweet flavor in we and it is mild-natured, the heart, liver, large intestine can be entered, promoting blood circulation acts on very Extensively, closed dysmenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, lung carbuncle acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma are used for.Almond in we is micro- Temperature, sweet in flavor, return lung, large intestine channel have beauty and skin care, hair care hair care, enhancing digestive system health, adjust blood pressure, is anti-inflammatory, preventing Diabetes, strong bone and tooth and other effects.Coix seed in we is cool in nature, sweet in flavor, light, can eliminate acne, freckle, old age Spot, cyasma, butterfly macules have good efficacy to furfur, acne, chap, pachylosis etc..Semen Ricini in we is sweet in flavor; It is pungent;It is flat, enter large intestine, lung channel, have detumescence and drawing out poison, apocenosis dispel corruption, dispelling wind and removing obstruction in the meridians, relieve oedema or abdominal distension through diuresis or purgation and rush down lower work(, face can be treated by being controlled outside clinic The illness such as paralysed dizzy scald.
The effect of all medicines remove necrosis and promote granulation with using, are clearing heat and detoxicating, blood stasis dispersing and fresh blood promoting.It is wherein monarch with Lu sand, blood-stasis-dissipating blood-circulation-promoting goes corruption Myogenic;It is dispelled corruption with brush-cherry seed, peach kernel, Semen Ricini detumescence and drawing out poison, apocenosis, principal drug assistance blood stasis dispersing and fresh blood promoting treats all kinds of obstinate skin diseases Suffer from, and can relax bowel, takes away the firewood under the cauldron, dispel internal perverse trend, make vital QI recovered after pathogens eliminated, be altogether ministerial drug;Coix seed invigorating the spleen for eliminating dampness makes wet Then heat of dispelling is lonely, damp and hot remove and sore from going, and can invigorating the spleen care for shield stomach Qi, be allowed to use for assistant.
In addition paste is made with high spirit, taken the length of hundred medicines " wine be ", slide the power of profit with its galloping disease, promotion drug is to saturating Skin gets twice the result with half the effort, for treating wart, birthmark, hemangioma, lipoma, mole, freckle, syringocystadenoma, corn etc..
The application method of externally applied ointment of the present invention is:After disease sites are cleaned up, after iodine disinfection, then directly It connects and plaster is coated on disease sites, one day using twice.
Beneficial effects of the present invention are:
(1)The externally applied ointment of the present invention is made of natural Chinese traditional medicines raw material, is coated in the position of morbidity, therapy letter It is single, it is significant in efficacy, mitigate the pain of patient;
(2)The externally applied ointment clinical application safety of the present invention, external application does not stimulate internal organ, while effectively preventing hospital-acquired infection, It has no toxic side effect;
(3)The externally applied ointment of the present invention is at low cost, carries and easy to use, is well received by the majority of patients.
Specific implementation mode
Embodiment 1
A kind of external-applied ointment of the present embodiment, includes the Chinese medicine material of following weight:Take Lu sand 12g, brush-cherry seed 10g, peach kernel 4g, almond 6g, coix seed 4g, Semen Ricini 6g when preparation, are uniformly mixed after above-mentioned Chinese medicine material is crushed to 100 mesh respectively, use 50 ° of white wine are adjusted to paste, are preserved under room temperature air-proof condition.
Plaster manufactured in the present embodiment is used for 30 wart patients, obviously becomes smaller after trying out once, is controlled using after 5-10 times More, patient's half a year is tracked, no case was recurrence, cure rate 100%.
Embodiment 2
A kind of external-applied ointment of the present embodiment, includes the Chinese medicine material of following weight:Take Lu sand 16g, brush-cherry seed 16g, peach kernel 8g, almond 8g, coix seed 8g, Semen Ricini 8g when preparation, are uniformly mixed after above-mentioned Chinese medicine material is crushed to 80 mesh respectively, use 50 ° of white wine are adjusted to paste, are preserved under room temperature air-proof condition.
Plaster manufactured in the present embodiment is as follows for following lipomas, hemangioma and syringocystadenoma patient, situation:
Huang, 80 years old, man, left back brain grew a goose egg big more than 20 years of sarcoma, after externally applied ointment manufactured in the present embodiment treatment, Sarcoma disappears within 15 days.
Zhang, 30 years old, man, the auris dextra door length of side went out a viviparous chondrosarcoma more than 10 years, through external plaster manufactured in the present embodiment After medicine treatment, sarcoma disappears after 7 days.
Mr. Wang, 66 years old, female, left eye subcutaneously grew the hemangioma of an a diameter of 10-15mm, through manufactured in the present embodiment outer After plaster treatment, sarcoma disappears after 8 days.
Liu, 21 years old, female, the eyes length of side expired the syringocystadenoma of a diameter of 2-4mm for many years, through external plaster manufactured in the present embodiment After medicine treatment, sarcoma disappears after 5 days.
Hu, 65 years old, man, right nasal side face grew the hemangioma for being about 3cm, was treated through externally applied ointment manufactured in the present embodiment Afterwards, sarcoma disappears after 5 days.
Above-mentioned patient's half a year is tracked, no case was recurrence, cure rate 100%.
Embodiment 3
A kind of external-applied ointment of the present embodiment, includes the Chinese medicine material of following weight:Take Lu sand 6g, brush-cherry seed 6g, peach kernel 4g, Almond 4g, coix seed 4g, Semen Ricini 4g when preparation, are uniformly mixed, with 50 ° after above-mentioned Chinese medicine material is crushed to 90 mesh respectively White wine is adjusted to paste, is preserved under room temperature air-proof condition.
Plaster manufactured in the present embodiment is used for birthmark patient, situation is as follows:
Take certain, 60 years old, female, left eye subcutaneously grew the black birthmark of an a diameter of 3-4cm, through externally applied ointment manufactured in the present embodiment After treatment, birthmark disappears after 7 days.
Certain is thanked, 16 years old, female, right eye subcutaneously grew the black wool birthmark of an a diameter of 1cm, through external plaster manufactured in the present embodiment After medicine treatment, birthmark disappears after 3 days.
Leaf, it is 26 years old, male, one piece of black birthmark is grown on hip, after externally applied ointment manufactured in the present embodiment treatment, Birthmark disappears after 5 days.
Embodiment 4
A kind of external-applied ointment of the present embodiment, includes the Chinese medicine material of following weight:Take Lu sand 16g, brush-cherry seed 16g, peach kernel 10g, almond 10g, coix seed 10g, Semen Ricini 10g, when preparation, above-mentioned Chinese medicine material is crushed to respectively after 80 mesh mix it is equal It is even, it is adjusted to paste with 50 ° of white wine, is preserved under room temperature air-proof condition.
Plaster manufactured in the present embodiment is used for corn patient, situation is as follows:
Hu, 26 years old, the corn of a soya bean size was grown at female, left foot bottom, after externally applied ointment manufactured in the present embodiment treatment, 3 Corn disappears after it.
Often certain, 32 years old, male, the corn of right crus of diaphragm footing palm one soya bean size of length, through external plaster manufactured in the present embodiment After medicine treatment, corn disappears after 3 days.
Lee, 44 years old, man, the corn of one soya bean size of left foot footing followed by director, through external application manufactured in the present embodiment After plaster treatment, corn disappears after 3 days.
Liu, 41 years old, the corn of a soya bean size was grown at man, left foot bottom, was treated through externally applied ointment manufactured in the present embodiment Afterwards, corn disappears after 3 days.
Embodiment 5
A kind of external-applied ointment of the present embodiment, includes the Chinese medicine material of following weight:Take Lu sand 8g, brush-cherry seed 8g, peach kernel 4g, Almond 4g, coix seed 4g, Semen Ricini 4g when preparation, are uniformly mixed, with 50 ° after above-mentioned Chinese medicine material is crushed to 80 mesh respectively White wine is adjusted to paste, is preserved under room temperature air-proof condition.
Ointment manufactured in the present embodiment is used for 8 freckle patients, the diminution of freckle area, color are thin out after trying out once, It is cured using after 3-5 times, tracks patient's half a year, no case was recurrence, cure rate 100%.
Embodiment 6
A kind of external-applied ointment of the present embodiment, includes the Chinese medicine material of following weight:Take Lu sand 12g, brush-cherry seed 12g, peach kernel 8g, almond 8g, coix seed 8g, Semen Ricini 8g when preparation, are uniformly mixed after above-mentioned Chinese medicine material is crushed to 100 mesh respectively, use 50 ° of white wine are adjusted to paste, are preserved under room temperature air-proof condition.
Ointment manufactured in the present embodiment is used for the patient that 12 different parts have moles, patient is bright using effect after 3-5 times It is aobvious, it is used continuously 15-20 days and all cures, cure rate 100%.

Claims (5)

1. a kind of external-applied ointment, it is characterised in that include the Chinese medicine material of following weight parts:
3-8 parts of brush-cherry seed of 3-8 parts of Lu sand
2-5 parts of almond of 2-5 parts of peach kernel
2-5 parts of Semen Ricini of 2-5 parts of coix seed;
When preparation, it is uniformly mixed after above-mentioned Chinese medicine material is crushed to 80-100 mesh, paste is adjusted to white wine, in room temperature sealing strip It is preserved under part.
2. a kind of external-applied ointment according to claim 1, it is characterised in that the weight part ratio of each Chinese medicine material is:
4-6 parts of brush-cherry seed of 4-6 parts of Lu sand
2-4 parts of almond of 2-4 parts of peach kernel
2-4 parts of Semen Ricini of 2-4 parts of coix seed.
3. a kind of external-applied ointment according to claim 1, it is characterised in that the weight part ratio of each Chinese medicine material is:
6 parts of Lu sand, 5 parts of brush-cherry seed
2 parts of peach kernel, 3 parts of almond
2 parts of coix seed, 3 parts of Semen Ricini.
4. a kind of external-applied ointment according to claim 1, it is characterised in that the weight part ratio of each Chinese medicine material is:
8 parts of Lu sand, 8 parts of brush-cherry seed
4 parts of peach kernel, 4 parts of almond
4 parts of coix seed, 4 parts of Semen Ricini.
5. a kind of external-applied ointment according to any one of claim 1-4, it is characterised in that:The white wine is 50 ° white Wine.
CN201810420184.5A 2018-05-04 2018-05-04 A kind of external-applied ointment Pending CN108310273A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810420184.5A CN108310273A (en) 2018-05-04 2018-05-04 A kind of external-applied ointment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810420184.5A CN108310273A (en) 2018-05-04 2018-05-04 A kind of external-applied ointment

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CN108310273A true CN108310273A (en) 2018-07-24

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110384763A (en) * 2019-08-20 2019-10-29 江苏博润医疗集团有限公司 It is a kind of for treating the external drug of birthmark

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110384763A (en) * 2019-08-20 2019-10-29 江苏博润医疗集团有限公司 It is a kind of for treating the external drug of birthmark

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Application publication date: 20180724