CN107929330A - A kind of anti-tumor rheumatism herb mixture for coordinating bee to treat and its preparation method and application - Google Patents
A kind of anti-tumor rheumatism herb mixture for coordinating bee to treat and its preparation method and application Download PDFInfo
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- CN107929330A CN107929330A CN201711193867.3A CN201711193867A CN107929330A CN 107929330 A CN107929330 A CN 107929330A CN 201711193867 A CN201711193867 A CN 201711193867A CN 107929330 A CN107929330 A CN 107929330A
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Abstract
The present invention relates to a kind of anti-tumor rheumatism herb mixture for coordinating bee to treat and preparation method thereof, includes the raw material that following parts by weight match：Ripe 120~150 parts of honey, fresh sweet 50~80 parts of royal jelly, 500~800 parts of seaweed, 10~30 parts of propolis ethanol solution, 10~30 parts of Bee Pollen, 3~5 parts of queen bee nit.The present invention can effectively prevent bee venom allergy, significantly reduce adverse reaction rate, and have with bee-needle therapy in clinical efficacy and cooperate with summation action, test ratings such as symptom, erythrocyte sedimentation rate, Acute radiation reaction, immunoglobulin, leucocyte such as the morning stiffness caused by rheumatism, tumor disease, pain in the back, cold and hot sensitive, lower limb are heavy, weak, constipation, pain etc. are can effectively improve to have clear improvement；By righting come antirheumatic, antitumor, improvement tumor patient chemicotherapy adverse reaction, improvement rheumatism and tumor patient immune function, to radiotherapy and chemotherapy medicine attenuation synergistic, improve patients ' life quality, extend patient survival.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of anti-tumor rheumatism herb mixture for coordinating bee to treat and
Its preparation method and application.
Background technology
Rheumatism majority is autoimmune disease, is a series of diseases in internal medicine in hospital field, mainly invades human body
Joint, muscle, the soft tissue of bone and periarticular, such as tendon, ligament, synovial bursa, fascia position.It is immunized to rheumatism related
Common disease have lesion of autoimmune connective tissue disease, systemic vasculitis, bone and joint etc..The traditional Chinese medical science thinks：Vital essence is lost
Void, it is evil from interior life.The generation of rheumatism, prevailing relationship to healthy tendency are invaded, fallen ill with the aspect of perverse trend two, weakened body resistance heresy.Work as human righteousness
Insufficient or relatively weak, perverse trend can multiply the void of ferritic or the void for multiplying a period of time and invade human body.Site of pathological change mostly be empty place by heresy, have
In muscles and bones tendon and vessel person, have in internal organs person, sick position is different, and illness is different.Void is falls ill originally, and the generation of disease is drawn by perverse trend
Rise, the perverse trend of either external or interior life acts on human body, should be according to clinical manifestation as dialectical foundation.It is reported that I
97% suffers from spondylodynia in state's mid-aged population.Osteoarthropathy shows the trend of rejuvenation again, wherein because of neck, lumbar vertebra disease just
The number examined is more than 80%, and the crowd of 20 years old to 40 years old accounts for more than half of medical number, and clinical manifestation goes out miserable, again
Write, pain, seriously affected quality of life.Tumour is body under the effect of various carcinogenic factors, and some of local organization is thin
Born of the same parents lose the normal regulation to its growth at the genetic level, and the neoformation for causing its clonal abnormality hyperplasia and being formed, can divide
For benign tumour and malignant tumour, i.e. cancer.The internal cause of induced tumor include mental element, endocrine disorder, immune deficiency with
Inherent cause etc..In the crowd of congenital immune deficiency or prolonged application immunosuppressive drug, the incidence of tumour is higher.
Moxibustion therapy is that to sting organ be needle set to human use honeybee, follows channels and collaterals skin zone and the pin of different gimmicks is implemented at acupuncture point
Thorn, in a kind of method of disease preventing and treating, bee pin is automatically injected intracutaneous suitable both to human meridian point with mechanical stimulus
Bee pin liquid, uniqueness can be played for illnesss such as rheumatism, rheumatoid arthritis, hypoimmunity, fibroid, osteoproliferations
Pharmacological action.But bee venom allergic phenomena easily occurs during bee-needle therapy, often brings discomfort to patient, some patientss allergy is tight
Weight, be difficult to self-healing, so as to reduce the compliance that patient receives Moxibustion therapy.The method for solving common bee venom allergy is mostly to wait suffering from
Person's self-healing or using external used medicine, is mostly to use Claritin merely for severe allergy person, cannot be to Moxibustion therapy
To booster action.
The content of the invention
For easily occur in Moxibustion therapy bee venom allergic phenomena, in the prior art solve bee venom allergy method cannot be right
Moxibustion therapy plays the problem of booster action, and the present invention provides a kind of anti-tumor rheumatism herb mixture for coordinating bee to treat.
And the present invention also provides a kind of preparation method for the anti-tumor rheumatism herb mixture for coordinating bee to treat.
And the present invention also provides a kind of anti-tumor rheumatism herb mixture for coordinating bee to treat in terms of anti-tumor rheumatism
Application.
To achieve the above object of the invention, the embodiment of the present invention employs following technical solution：
A kind of anti-tumor rheumatism herb mixture for coordinating bee to treat, includes the raw material of following parts by weight proportioning：Ripe bee
120~150 parts of honey, fresh sweet 50~80 parts of royal jelly, 500~800 parts of seaweed, 10~30 parts of propolis ethanol solution, Bee Pollen 10~
30 parts and 3~5 parts of queen bee larva.
Relative to the prior art, the anti-tumor rheumatism herb mixture provided by the present invention for coordinating bee to treat coordinates bee acupuncture
Treat, can effectively prevent bee venom allergy, significantly reduce adverse reaction rate, also, the present invention has with bee-needle therapy in clinical efficacy
Cooperate with summation action, can effectively improve morning stiffness caused by rheumatism, tumor disease, pain in the back, it is cold and hot it is sensitive, lower limb are heavy, weak, just
Test rating such as the symptoms such as secret, pain, erythrocyte sedimentation rate, Acute radiation reaction, immunoglobulin, leucocyte etc. has clear improvement.This hair
The bright pharmacological action and its interaction for combining ripe honey, fresh sweet royal jelly, seaweed, propolis, Bee Pollen and queen bee nit,
Equilibrium between yin and yang is adjusted by righting in terms of anti-tumor rheumatism, improves immune status, fundamentally strengthens the anti-heresy of body
Ability, reach antirheumatic, it is antitumor, improve tumor patient chemicotherapy adverse reaction, improve rheumatism and tumor patient immune function,
To radiotherapy and chemotherapy medicine attenuation synergistic, so as to improve patients ' life quality, extend the effect of patient survival, treatment rheumatism itself is exempted from
The clinical effective rate of epidemic disease and tumor disease is up to 98%.
By the ratio of the preferred above component herb mixture is made in the present invention, acts synergistically between each component, windproof, help
Just, attenuation, synergy, coordinate Moxibustion therapy preferably to improve autoimmunity, reach antirheumatic, antitumor effect, and
Reduce the adverse reaction of bee venom allergy.
It is described to match somebody with somebody present invention also offers a kind of preparation method for the anti-tumor rheumatism herb mixture for coordinating bee to treat
Anti-tumor rheumatism herb mixture that bee is treated is closed by the raw material through decocting, concentrating, cooling down, mixing.
The preparation method process greatly improves the biological utilisation for decocting active ingredient in raw material by decocting process
Degree, it is easier to absorb and play effect, the concentration of active ingredient in product is controlled by concentrating, and adjust between each raw material
Ratio, makes raw material be incorporated in preference temperature in product, avoids the destruction of nutrition, finally mix up to product by cooling.
Coordinate the anti-tumor rheumatism herb mixture that bee is treated as anti-tumor rheumatic medicine the present invention also provides a kind of
Using.
The present invention plays antirheumatic, antineoplastic action by improving patient immune function, and radiotherapy and chemotherapy medicine is subtracted
Malicious synergy, improves patients ' life quality, extends its life cycle.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.
The embodiment of the present invention provides a kind of anti-tumor rheumatism herb mixture for coordinating bee to treat, including following parts by weight are matched somebody with somebody
The raw material of ratio：Ripe 120~150 parts of honey, fresh sweet 50~80 parts of royal jelly, 500~800 parts of seaweed, propolis ethanol solution 10~
3~5 parts of 30 parts, 10~30 parts of Bee Pollen and queen bee larva.
Relative to the prior art, the anti-tumor rheumatism herb mixture provided by the present invention for coordinating bee to treat combines maturation
The pharmacological action and its interaction of honey, fresh sweet royal jelly, seaweed, propolis, Bee Pollen and queen bee nit, in anti-tumor rheumatism
Aspect adjusts equilibrium between yin and yang by righting, improves immune status, fundamentally strengthens the anti-evil ability of body, and reaches anti-
Rheumatism, antitumor, improvement tumor patient chemicotherapy adverse reaction, improve rheumatism and tumor patient immune function, to chemicotherapy medicine
Thing attenuation synergistic, so as to improve patients ' life quality, extend the effect of patient survival.
Honey gathers back nest brewing from plant flower by honeybee and forms as a kind of traditional Chinese medicine.Mainly contain more than 60
The various nutriments of kind needed by human body.According to《Sheng Nong's herbal classic》Record：" honey is sweet flat nontoxic, and main invigorating middle warmer and replenishing QI, long term usage is made light of one's life by commiting suicide
Macrobiosis.”《Compendium of Materia Medica》Record：" honey life is then cool in nature, therefore energy heat-clearing, ripe then warm-natured, therefore energy bowl spares, sweet and gentle, therefore can solve
Poison, soft and Ru Ze, therefore can moisturize, its work(being used as medicine has five, and heat-clearing, bowl spares, removing toxic substances, moisturizes, and relieves pain." modern
Medical research proves, honey have anti-inflammatory, antibacterial, it is anti-oxidant, antitumor, promote regeneration, be aid digestion, relax bowel, tie up
Shield heart blood vessel, moisten the lung and relieve the cough, adjust the multiple biological activities such as blood glucose and sleep, can treat the organs such as the heart, liver,spleen,kidney, lung, intestines
Disease.It is used for coordinating the drug actions of a prescription in we.
Contain a variety of antitumorigenic substances such as unrighted acid such as royal jelly acid, a- nonyls diluted acid, decanedioic acid in fresh honey royal jelly, also
Containing high active substances such as abundant more than 20 kinds of amino acid, nucleic acid, enzyme, polypeptide, multivitamin and protein, can promote
The development of the immunocytes such as spleen, thymus gland, marrow and lymphoid tissue and immune organ, stimulates body to produce antibody, increases serum
Total protein and gamma globulin content, activated T lymphocytes and bone-marrow-derived lymphocyte activity, can adjust immune system and enhancing is exempted from
Epidemic disease ability, and then strengthen its antirheumatic, antitumous effect.The fresh sweet royal jelly that the present invention uses is the royal jelly of fresh collection, with
The synthesis royal jelly for being free of or having inactivated part active ingredient is compared, and active ingredient species is more in fresh honey royal jelly, after being long placed in
Royal jelly compare, fresh honey royal jelly effect is stronger.In addition, have very containing the royal jelly acid for being known as longevity factor in fresh honey royal jelly
Good sterilization, bacteriostasis and antitumor, anti-radiation function, and to protecting the active material in fresh sweet royal jelly to have important meaning
Justice, can substantially increase the effectiveness of health care and the medical treatment of royal jelly.Seaweed resolving phlegm and softening hard masses, reducing fever and causing diuresis, ox sulphur contained therein
Acid can supplement bee slurry in content of taurine, have the function that promote organism immunity enhancing with it is antifatigue.Contained by seaweed
Polysaccharide have be remarkably reinforced cellular immunity and humoral immune function, lymphocyte transformation can be promoted, improve the immunity of body.
It is further preferred that the fresh sweet royal jelly is derived from queen bee tire nest, when take-off time ＜ 72 is small.Take-off time more it is short then
Active ingredient retains more in fresh honey royal jelly, and active ingredient significantly reduces in the fresh sweet royal jelly reused after being long placed in, up to not
To technique effect expected from the present invention.
It is further preferred that the fresh sweet royal jelly is derived from queen bee tire nest, when take-off time ＜ 24 is small.24 when small it is interior effectively into
Divide content higher, product can be made preferably to play raising immunity, so as to reach antitumor, antirheumatic effect.
Contain a variety of flavone compounds in propolis, human body can be helped to prevent a variety of diseases, make body various functions normal
Change, enhancingization, wherein there is Quercetin cough-relieving, dispel scorching, analgesia, antiviral etc. to act on, and can not only suppress a variety of carcinogenic substances, and
And the growth of kinds of tumor cells can also be suppressed.In addition, also containing a variety of organic acids in propolis, wherein caffeic acid has hemostasis, town
Cough, phlegm-dispelling functions, moreover it is possible to suppress the growth and generation of colon tumor cell.In the present invention, propolis is except performance righting anti-inflammatory
Effect is outer, moreover it is possible to sterilizes, sterilizes, sterilizing, is antibacterial, is mould proof, anti-corrosion, preservation is played to other compositions.Propolis and ethanol one
Rise after solution is made, be more conducive to the performance of propolis effect, resulting solution can increase the disease resistance of human body, can accelerate body
Histiocytic regeneration, can also increase their anti-virus ability, have obvious adjustment effect to the immune system of the mankind, together
When, propolis ethanol solution also has the multiple efficacies such as degrading the channel, promoting blood circulation, and can reduce hemoglobin oxidation in blood of human body and react
Appearance, ossify to blood vessel and hypostasis have obvious prevention effect, reduce the generation of all kinds of cardiovascular and cerebrovascular diseases.
It is further preferred that in the propolis ethanol solution, quality percentage of the propolis in the propolis ethanol solution contains
Measure as 25~35%, then propolis cannot be substantially dissolved in ethanol solution excessive concentration, waste propolis, the too low then ethanol of concentration
Propolis content in solution is too small, does not reach expected therapeutic effect；Ethanol includes edible alcohol, yellow rice wine, is commercially available be easy to get
And inexpensive ethanol species；The mass concentration of ethanol be 20~60%, preferable concentration can dissolve propolis, concentration too it is low then
Propolis dissolving is insufficient, and concentration too Gao Zehui makes ethanol content in finished product higher, influences mouthfeel.
Bee Pollen contain protein, amino acid, vitamin, Bee Pollen element, trace element, organized enzyme, flavone compound,
The nutritional ingredients such as lipid, nucleic acid, brassin, phytic acid, nutrition is comprehensive, can prevent brain cardiovascular disease, reducing blood lipid, adjust nerve
System, promote sleep, adjust gastronintestinal system function, promote digestion, treatment habitual constipation, can overcome in human metabolism
Existing various disorders, adjust endocrine, improve body's immunity, anti-aging, etc. have certain effect, also have
Obvious anti-cancer tumor suppressor and liver protecting, prevent the function such as anaemia, diabetes, antifatigue.Contained pollen polysaccharide in Bee Pollen
With very strong immunocompetence, the phagocytosis activity of energy activating macrophage, improves human disease resistance, plays obvious antitumor
Effect.
Queen bee nit contains extremely abundant protein (accounting for more than the 40% of dry matter when lyophilized), more than 16 kinds amino
Nearly 20 kinds of mineral matters such as acid, multivitamin, calcium, zinc, iron, copper, selenium, manganese, magnesium and trace element, superoxide dismutase,
Taurine etc., to lasting adjusting human physiological functions, activated cell vigor, improving immunity of organisms has remarkable efficacy.Queen bee
Larva has the effect of strong kidney and strengthening spleen, and the traditional Chinese medical science thinks, immune function is the vital essence category of kidney, " just arrogant, heresy can not be done ", only
The vital essence of people is sufficient, blood vessels are vigorous, in vigorous health, will not just be attacked by external disease and evil, could maintain each internal organs organ
Physiological function it is normal.So the immunity function of human body relies on the actual situation of kidney, queen bee nit can improve body by kidney tonifying
Immunity, so as to strengthen antirheumatic, antineoplastic action.
It is further preferred that the queen bee larva is the thing fine powder that dries in the shade of queen bee nit, using the processing procedure to dry in the shade
It can be aoxidized to avoid the active ingredient in queen bee nit under illumination or hot conditions, retain active ingredient as much as possible.
The embodiment of the present invention also provides a kind of preparation method for the anti-tumor rheumatism herb mixture for coordinating bee to treat, described to match somebody with somebody
Anti-tumor rheumatism herb mixture that bee is treated is closed by the raw material through decocting, concentrating, cooling down, mixing.
The preparation method process greatly improves the biological utilisation for decocting active ingredient in raw material by decocting process
Degree, it is easier to absorb and play effect, the concentration of active ingredient in product is controlled by concentrating, and adjust between each raw material
Ratio, makes raw material be incorporated in preference temperature in product, avoids the destruction of nutrition, finally mix up to product by cooling.
Specifically, the step is：
Step a, each raw material components are weighed by raw material proportioning, seaweed is added water to cook, concentrated, obtain seaweed concentrate；
Step b, ripe honey is added into seaweed concentrate obtained by step a, is decocted；Bee Pollen is added, stirring is extremely dissolved,
Cooling；
Step c, fresh sweet royal jelly, queen bee larva, propolis ethanol solution will be added in mixed liquor obtained by step b, mixing is equal
Low temperature is concentrated up to product after even.
The quality of water described in above-mentioned steps a is 3~5 times of seaweed quality, and the water of the dosage can be such that seaweed all soaks
Bubble, in favor of the abundant extraction of active ingredient in seaweed；It is described decoct for decoct 2~3 times, 15~25 minutes every time, after decoction
Collecting decoction, can form funneling effect decocting solution by repeatedly decocting, accelerate the dissolution of active ingredient in seaweed, improve
Extraction efficiency；The concentration can make solution reach expected concentration to be concentrated into the 40~60% of original volume, by concentration, rear
Can reach suitable proportioning with other raw materials in continuous mixed process, in favor of preferably played between each raw material synergistic effect,
Heighten the effect of a treatment.
In above-mentioned steps b, the Bee Pollen adds immediately after the completion of decoction, at this time solution temperature temperature close to boiling,
Temperature is higher, is conducive to the dissolving of Bee Pollen.If solution cooling after add, Bee Pollen be not easy it is dispersed in the solution,
Make the Bee Pollen uniformity of dosage units in solution bad.
It is further preferred that the decocting time is 20~30 minutes., can be further by ripe honey by decocting
May remaining poisonous alkaloids destruction.It is usually relatively low with rheumatism, patient's immunity of tumour, to extraneous undesirable element or
The tolerance of noxious material is relatively low, therefore the directly edible honey containing toxin is likely to occur poisoning, dizzy headache occurs, dislikes
Situations such as heart vomiting, diarrhea abdominal pain, asthma allergy.
It is further preferred that described be cooled to be cooled to 5~30 DEG C.Nutrients in fresh honey royal jelly, queen bee nit, propolis
Matter and active ingredient do not tolerate high temperature, so add above-mentioned raw materials after solution is cooled down, avoid nutriment and activity into
Divide destroyed.
In above-mentioned steps c, the low temperature concentration concentrates for low-temperature reduced-pressure, and temperature range is 5~30 DEG C, and being concentrated into volume is
The 15~25% of former mixed liquor volume.Low-temperature reduced-pressure concentration can be broken to avoid the active ingredient in product because of high temperature
It is bad, thickening efficiency can be improved using the method being concentrated under reduced pressure, shorten the operating time；After being concentrated into preferred volume, in product
Active constituent content is higher, it is not necessary to which enough active ingredient can be absorbed by taking excess dosage, be concentrated into solution overrich, then
Products obtained therefrom is excessively sticky, is not easy to dispense and quantitatively takes.
In order to better illustrate embodiment of the present invention, illustrated below by embodiment is further.
Embodiment 1
An embodiment of the present invention provides a kind of anti-tumor rheumatism herb mixture for coordinating bee to treat, including following parts by weight
The raw material of proportioning：Ripe 120 parts of honey, fresh sweet 80 parts of royal jelly, 500 parts of seaweed, 30% 30 parts of (matter of yellow rice wine of propolis yellow rice wine solution
Measure percent concentration for 20%), 3 parts of 10 parts of Bee Pollen and queen bee larva.
Preparation method：
Step a, seaweed is weighed by raw material proportioning, with 2 decoctions of moisture of 4 times of quality, decocts 25 minutes every time, merge and decoct
Boil liquid, is concentrated into 1000mL, obtains seaweed concentrate；
Step b, the ripe honey weighed according to raw material proportioning is added into seaweed concentrate obtained by step a, decocts 20 points
Clock；The Bee Pollen weighed by raw material proportioning is added after the completion of decoction immediately, stirring is cooled to 5 DEG C to dissolving；
Step c, fresh sweet royal jelly, queen bee larva, the propolis weighed by raw material proportioning will be added in mixed liquor obtained by step b
Ethanol solution, carries out low-temperature reduced-pressure at 5 DEG C after mixing and is concentrated into 200mL up to product.
Instructions of taking：
It is administered at empty stomach.Take 1 time, be taken at bed time at night with 1 time after getting up morning, each 10ml.
Embodiment 2
An embodiment of the present invention provides a kind of anti-tumor rheumatism herb mixture for coordinating bee to treat, including following parts by weight
The raw material of proportioning：Ripe 130 parts of honey, fresh sweet 70 parts of royal jelly, 650 parts of seaweed, 10 parts of 25% propolis edible alcohol solution are (edible
The mass percent concentration of alcohol for 40%), 5 parts of 20 parts of Bee Pollen and queen bee larva.
Preparation method：
Step a, seaweed is weighed by raw material proportioning, with 2 decoctions of moisture of 3 times of quality, decocts 20 minutes every time, merge and decoct
Boil liquid, is concentrated into 780mL, obtains seaweed concentrate；
Step b, the ripe honey weighed according to raw material proportioning is added into seaweed concentrate obtained by step a, decocts 25 points
Clock；The Bee Pollen weighed by raw material proportioning is added after the completion of decoction immediately, stirring is cooled to 15 DEG C to dissolving；
Step c, fresh sweet royal jelly, queen bee larva, the propolis weighed by raw material proportioning will be added in mixed liquor obtained by step b
Ethanol solution, carries out low-temperature reduced-pressure at 15 DEG C after mixing and is concentrated into 117mL up to product.Up to product.
Instructions of taking is the same as embodiment 1.
Embodiment 3
An embodiment of the present invention provides a kind of anti-tumor rheumatism herb mixture for coordinating bee to treat, including following parts by weight
The raw material of proportioning：Ripe 150 parts of honey, fresh sweet 50 parts of royal jelly, 800 parts of seaweed, 20 parts of 35% propolis edible alcohol solution are (edible
The mass percent concentration of alcohol for 60%), 4 parts of 30 parts of Bee Pollen and queen bee larva.
Preparation method：
Step a, seaweed is weighed by raw material proportioning, with 3 decoctions of moisture of 5 times of quality, decocts 15 minutes every time, merge and decoct
Boil liquid, is concentrated into 2400mL, obtains seaweed concentrate；
Step b, the ripe honey weighed according to raw material proportioning is added into seaweed concentrate obtained by step a, decocts 30 points
Clock；The Bee Pollen weighed by raw material proportioning is added after the completion of decoction immediately, stirring is cooled to 30 DEG C to dissolving；
Step c, fresh sweet royal jelly, queen bee larva, the propolis weighed by raw material proportioning will be added in mixed liquor obtained by step b
Ethanol solution, is concentrated into 600mL up to product in 30 DEG C of low-temperature reduced-pressures after mixing.Up to product.
Instructions of taking is the same as embodiment 1.
Clinical test
Subjects：Receive the immunological diseases patient totally 200 of bee-needle therapy, men and women is fifty-fifty, and the age is 20~40 years old.
Test material：The gained of embodiment 1 coordinates the anti-tumor rheumatism herb mixture that bee is treated.It is administered at empty stomach daily, morning
Take 1 time, be taken at bed time at night with 1 time after getting up, each 10ml.
After taking 10 days, clinical test results are counted, are shown in Table 1~table 3.
1 Symptom Observation table of table
2 inflammation target improvement of table observes table
| Project | Before treatment | After treatment | P |
| Erythrocyte sedimentation rate (mm/h) | 44.33±2.51 | 41.70±5.01 | 0.649 |
| Anti- chain O (U) | 300.61±10.14 | 159.28±13.55 | 0.125 |
| Rheumatoid factor (IU/ml) | 48.74±5.33 | 26.93±3.96 | 0.039 |
| Leucocyte (× 109) | 6.93±0.88 | 5.33±0.78 | 0.214 |
| Acute radiation reaction (mg/dl) | 28.04±3.12 | 15.78±3.01 | 0.279 |
| Immunoglobulin IgA (IU/m) | 5.84±0.73 | 3.61±0.77 | 0.233 |
| Immunoglobulin G IgG (IU/m) | 19.11±2.62 | 19.00±1.02 | 0.125 |
Table is observed in 3 adverse reaction of table
From above clinical testing data as it can be seen that the embodiment of the present invention 1 provided with bee treat anti-tumor rheumatism in
Medicament mixture in the immunological diseases patient for receiving bee-needle therapy, to patient's morning stiffness, pain in the back, cold and hot sensitivity, multi-joint lesion,
The symptoms such as lower limb are heavy, which improve, significant effect；For inflammation index (such as：Rheumatoid factor, anti-chain O, immune globulin
It is white etc.) there is the improvement of conspicuousness；There are confrontation effect well, expiratory dyspnea, the hair of itch to adverse reaction
Raw rate is only 0.5%, and the incidence of redness and swelling of joints is only 1.0%.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
Any modification, equivalent substitution or improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (10)
- A kind of 1. anti-tumor rheumatism herb mixture for coordinating bee to treat, it is characterised in that：Include the original of following parts by weight proportioning Material：Ripe 120~150 parts of honey, fresh sweet 50~80 parts of royal jelly, 500~800 parts of seaweed, 10~30 parts of propolis ethanol solution, bee 3~5 parts of 10~30 parts of pollen and queen bee larva.
- 2. the anti-tumor rheumatism herb mixture according to claim 1 for coordinating bee to treat, it is characterised in that：The fresh sweet king Slurry is derived from queen bee tire nest, when take-off time ＜ 72 is small.
- 3. the anti-tumor rheumatism herb mixture according to claim 2 for coordinating bee to treat, it is characterised in that：The fresh sweet king Slurry is derived from queen bee tire nest, when take-off time ＜ 24 is small.
- 4. the anti-tumor rheumatism herb mixture according to claim 1 for coordinating bee to treat, it is characterised in that：The queen bee children Worm powder is the thing fine powder that dries in the shade of queen bee nit.
- 5. the anti-tumor rheumatism herb mixture according to claim 1 for coordinating bee to treat, it is characterised in that：The propolis second In alcoholic solution, mass percentage of the propolis in the propolis ethanol solution is 25~35%；And/orEthanol in the propolis ethanol solution includes edible alcohol, yellow rice wine；And/orIn the propolis ethanol solution, the mass concentration of ethanol is 20~60%.
- 6. a kind of claim 1-5 any one of them coordinates the preparation method of the anti-tumor rheumatism herb mixture of bee treatment, its Be characterized in that, it is described coordinate bee treat anti-tumor rheumatism herb mixture by the raw material through decoct, concentrate, cool down, mix and Into.
- 7. the preparation method of the anti-tumor rheumatism herb mixture according to claim 6 for coordinating bee to treat, it is characterised in that Specifically include following steps：Step a, each raw material components are weighed by raw material proportioning, seaweed is added water to cook, concentrated, obtain seaweed concentrate；Step b, ripe honey is added into seaweed concentrate obtained by step a, is decocted；Bee Pollen is added, stirring is cold to dissolving But；Step c, fresh sweet royal jelly, queen bee larva, propolis ethanol solution will be added in mixed liquor obtained by step b, after mixing Low temperature is concentrated up to product.
- 8. the preparation method of the anti-tumor rheumatism herb mixture according to claim 7 for coordinating bee to treat, it is characterised in that It is decoction 2~3 times to be decocted described in the step a, 15~25 minutes every time, collecting decoction after decoction；And/orDecocting time described in the step b is 20~30 minutes；And/orConcentration described in the step a is to be concentrated into the 40~60% of original volume；And/orThe quality of water described in the step a is 3~5 times of seaweed quality.
- 9. the preparation method of the anti-tumor rheumatism herb mixture according to claim 7 for coordinating bee to treat, it is characterised in that Bee Pollen adds immediately after the completion of decoction described in the step b；And/orIt is cooled to be cooled to 5~30 DEG C described in the step b；And/orThe concentration of low temperature described in the step c concentrates for low-temperature reduced-pressure, and temperature range is 5~30 DEG C, and it is former mixed to be concentrated into volume Close the 15~25% of liquor capacity.
- 10. any one of claim 1-5 is described to coordinate the anti-tumor rheumatism herb mixture that bee is treated as anti-tumor medicine for rheumatism The application of thing.
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| CN201711193867.3A Pending CN107929330A (en) | 2017-11-24 | 2017-11-24 | A kind of anti-tumor rheumatism herb mixture for coordinating bee to treat and its preparation method and application |
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Citations (4)
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|---|---|---|---|---|
| CN1593192A (en) * | 2003-09-09 | 2005-03-16 | 陈振义 | Composite honeybee product and its preparation method |
| CN101502306A (en) * | 2008-10-29 | 2009-08-12 | 中国农业科学院蜜蜂研究所 | Bee product composition and preparation method thereof |
| CN101744874A (en) * | 2009-09-09 | 2010-06-23 | 韩玉财 | Compound bee emulsion for resisting tumor and preparation method thereof |
| CN106616722A (en) * | 2017-02-03 | 2017-05-10 | 张文 | Edible-seaweed honey |
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- 2017-11-24 CN CN201711193867.3A patent/CN107929330A/en active Pending
Patent Citations (4)
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|---|---|---|---|---|
| CN1593192A (en) * | 2003-09-09 | 2005-03-16 | 陈振义 | Composite honeybee product and its preparation method |
| CN101502306A (en) * | 2008-10-29 | 2009-08-12 | 中国农业科学院蜜蜂研究所 | Bee product composition and preparation method thereof |
| CN101744874A (en) * | 2009-09-09 | 2010-06-23 | 韩玉财 | Compound bee emulsion for resisting tumor and preparation method thereof |
| CN106616722A (en) * | 2017-02-03 | 2017-05-10 | 张文 | Edible-seaweed honey |
Non-Patent Citations (1)
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| 全国三绿工程工作办公室主编: "《安全优质蜂产品的选购与消费》", 30 April 2005, 中国农业出版社 * |
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