CN105388313B - A kind of reagent fluid control apparatus of DNA sequencer - Google Patents
A kind of reagent fluid control apparatus of DNA sequencer Download PDFInfo
- Publication number
- CN105388313B CN105388313B CN201510707072.4A CN201510707072A CN105388313B CN 105388313 B CN105388313 B CN 105388313B CN 201510707072 A CN201510707072 A CN 201510707072A CN 105388313 B CN105388313 B CN 105388313B
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- plate
- reagent
- pump
- control valve
- valve
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Saccharide Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The present invention relates to a kind of reagent fluid control apparatus of DNA sequencer, tube assembly is integrated including pump valve, it includes pump valve integrated base plate, and pump valve integrated base plate includes peristaltic pump installing plate, the fixed plate being connected with peristaltic pump installing plate, bottom plate, and above-mentioned each plate surrounds a ringent body structure；Control valve group is installed in the centre of the casing；Pump valve integrated base plate also includes being arranged on the control valve group installing plate among sipper pore group and bottom plate on bottom plate；Accordingly, control valve group is arranged on the center section of pump valve integrated base plate, and hydraulic pump is arranged on the sidepiece of pump valve integrated base plate, and fluid path control unit is set in the other side.The reagent fluid control apparatus of the DNA sequencer of the present invention, tube assembly is integrated using pump valve, and plurality of reagents can be selected simultaneously, and carries out sequencing reaction according to the order pre-set, and testing efficiency is high.
Description
Technical field
The present invention relates to DNA sequencing field, more particularly to a kind of reagent solution that can control the DNA sequencer for reacting liquid stream
Flow control device.
Background technology
During DNA sequencing, chemically reacted on sequence testing chip, produce visible ray, pass through CCD (Charge
Couple Device) optical signal caused by cameras capture sequencing reaction, you can obtain required sequencing information.
Agent delivery system provides plurality of reagents into reaction chip, it is desirable to which DNA sequencer can store, be defeated as desired
Send, and be convenient for changing reagent；Especially when selecting different reagents, special structure and pipeline need to be used lasting
Control is selected to different reagents, test reaction is completed to be delivered in time in reaction warehouse.
In view of drawbacks described above, creator of the present invention obtains this creation finally by prolonged research and practice.
The content of the invention
It is an object of the invention to provide a kind of reagent fluid control apparatus of DNA sequencer, to overcome above-mentioned technology
Defect.
To achieve the above object, the present invention provides a kind of reagent fluid control apparatus of DNA sequencer, including pump valve integrates
Tube assembly, it includes pump valve integrated base plate, and pump valve integrated base plate includes peristaltic pump installing plate, is connected with peristaltic pump installing plate
Fixed plate, bottom plate, above-mentioned each plate surrounds a ringent body structure；Control valve group is installed in the centre of the casing；
Pump valve integrated base plate also includes being arranged on the control valve group peace among sipper pore group and bottom plate on bottom plate
Loading board；Accordingly, control valve group is arranged on the center section of pump valve integrated base plate, and hydraulic pump is arranged on pump valve integrated base
The sidepiece of plate, fluid path control unit is set in the other side；
Multiple holes have been arranged side by side in sipper pore group on bottom plate, and syringe needle suction pipe passes through sipper pore, other end connection Reagent Tube
Connected with the fluid path port of corresponding control valve, valve integrate tube assembly by the syringe needle suction pipe of downside by reagent from buffer solution box installed
Unload and sucked in the Reagent Tube on platform assembly, and entered by the selection of fluid path control unit, drive control valve module and hydraulic pump
Row selection, reagent is discharged into reagent cartridge, carries out sequencing reaction.
Further, a control valve is connected in the port of export of the reagent bottle of each reaction reagent, each control valve is gone here and there successively
Connection, the outlet of a upper control valve connects with the entrance of next control valve；When in use, it need to only control and open a wherein control valve,
Then entered with the reagent solution that the control valve connects by pipeline in reaction warehouse.
Further, peristaltic pump mounting hole is provided with described peristaltic pump installing plate, two peristaltic pumps is set thereon；
Multiple reagent pipe clamps and wire clamp are also arranged at intervals on bottom plate.
Further, described fluid path control unit is isolated by a bending plate with fluid path part.
Further, two kinds of reagents are passed through simultaneously in reaction warehouse, one kind is buffer solution, and one kind is reaction reagent；Wherein, one
Individual peristaltic pump drives buffer solution to enter from buffer solution bottle in reaction warehouse；A kind of reaction reagent that the driving of another peristaltic pump determines with it is upper
The buffer solution mixed flow stated enters in reaction warehouse jointly.
Beneficial effects of the present invention are compared with prior art：The reagent fluid control apparatus of the DNA sequencer of the present invention,
Tube assembly is integrated using pump valve, plurality of reagents can be selected simultaneously, and be sequenced according to the order pre-set
Reaction, testing efficiency are high.
Pump valve assemblies are arranged in the cabinet space of multiple plate compositions, are easily installed on the diverse location of tester；
Multiple pin holes are set on plate, different reagents is selected, selection is accurate, reliable.
Buffer solution box installed unloads platform assembly, is not only able to the reagent of offer demand, moreover, handling reagent is convenient, saves case
Body space.
Brief description of the drawings
Fig. 1 is the dimensional structure diagram of the liquid case hoistable platform component of the present invention；
Fig. 2 is the side structure schematic view of the liquid case hoistable platform component of the present invention；
Fig. 3 a are the side structure schematic view of the base of the present invention；
Fig. 3 b are the structural representation of the position sensor mounting seat of the present invention；
Fig. 3 c are the structural representation of the position sensor mounting seat of the present invention；
Fig. 3 d are the structural representation of the support base of the present invention；
Fig. 3 e are the dimensional structure diagram of the nut mounting seat of the present invention；
Fig. 3 f are the dimensional structure diagram of the base of the present invention；
Fig. 4 a are that the pump valve of the present invention integrates the dimensional structure diagram of tube assembly；
Fig. 4 b are that the pump valve of the present invention integrates the backsight structural representation of tube assembly；
Fig. 4 c are that the pump valve of the present invention integrates the overlooking the structure diagram of tube assembly；
Fig. 4 d are the structural representation of the pump valve integrated base plate of the present invention；
Fig. 4 e are the fluid path schematic diagram of the liquid-supplying system of the present invention
Fig. 5 a are that the buffer solution box installed of the present invention unloads the dimensional structure diagram of platform assembly；
Fig. 5 b are that the buffer solution box installed of the present invention unloads the positive structure diagram of platform assembly；
Fig. 5 c are the structural representation that the buffer solution box installed of the present invention unloads the guide rail section of platform assembly；
Fig. 5 d are the structural representation that the buffer solution box installed of the present invention unloads the connecting plate of platform assembly；
Fig. 5 e are the structural representation that the buffer solution box installed of the present invention unloads the handle plate of platform assembly；
Fig. 5 f are the structural representation of the slideway of the present invention.
Embodiment
Below in conjunction with accompanying drawing, the forgoing and additional technical features and advantages are described in more detail.
Refer to shown in Fig. 1 and 2, the agent delivery device of the embodiment of the present invention includes liquid case hoistable platform component, and it is
The mechanism that pumps of motor leading screw driving, it is arranged in the right side casing of sequenator.It include motor 401,
The lead screw assembly that be connected with motor and support the support base 402 of motor, is connected with motor, installed in sidepiece
Liquid case lifting seat 408 is used in reaction, wherein, described reaction is with being equiped with buffer solution case loading/unloading platform group in liquid case lifting seat 408
Part, reaction is arranged on the installing plate 404 being connected with reaction with liquid case lifting seat with liquid case lifting seat 408, in screw mechanism
Under driving, carrying reaction is moved up and down with liquid case lifting seat Reagent Tube group.
The intermediate plate 4081 that reaction includes being connected with installing plate with liquid case lifting seat 408, it is arranged on the support of intermediate plate both sides
Plate 4082, horizontal ends are provided with supporting plate 4082, platform assembly is unloaded to place buffer solution box installed.
The output shaft of described motor 401 is connected with leading screw 403, and leading screw is arranged in base 405, base 405 with
The end of motor 401 is connected by support base 402；The sidepiece of base 405 is provided with stroke detection switch 406.
The output shaft of described motor is connected by shaft coupling 4035 with the connection end 4034 of leading screw；Connected on leading screw
There is nut 4031, nut is fixed on nut seat 4032；Leading screw lower end is provided with bearing (ball) cover by bearings, bearing end
4011。
The liquid case hoistable platform component of the embodiment of the present invention is moved reagent delivery to specified location, controlling party by guide rail
Just, precisely；Pump valve is integrated the gentle fliud flushing box installed of tube assembly and unloads platform assembly transport up and down by liquid case hoistable platform, and it is defeated to complete reagent
Send, course of reaction.
Refer to shown in Fig. 3 a-3f, guide rail 407 is additionally provided with the inside of base, reaction liquid case lifting seat 408 is installed
On guide rail slide block, with slide block movement；In reaction with being provided with position detection plate 4071 on liquid case lifting seat 408, on base
Position sensor is set, and it is arranged in position sensor mounting seat 4072.Incorporated by reference to shown in Fig. 3 b, it is position of the invention
Put the structural representation of sensor installation seat, it includes installing plate 4076, thereon set installation screwed hole 4077, by screw with
Base connects；Second detection plate 4074, sensor installing plate 4075, set in sensor installing plate 4075 and the second detection plate 4074
Slideway 4073 is put, with so that described position detection plate 4071 is by carrying out location sensitive.
Refer to shown in Fig. 3 c, the position detection plate of the embodiment of the present invention includes top installing plate 4081, by being arranged on
Screw in screwed hole 4082 is connected with reaction liquid case lifting seat 408；Also include the position detection part 4083 being connected,
Mutually to sense with position sensor.
Referring to shown in Fig. 3 d, described support base 402 includes connecting plate for electric motor 4021, and it is connected with motor end face, its
Upper setting connection screw thread hole 4022；The leading screw sleeve 4023 being connected, is provided with locating surface 4024 in leading screw sleeve, to pacify
Fill leading screw.
Refer to shown in Fig. 3 e, nut mounting seat includes nut mounting surface 4114, sets lead screw hole 4113, nut peace thereon
The surrounding in dress face 4114 sets trip bolt hole；The mounting surface 4112 being connected with lifting seat installing plate 404 is set in upper surface.
Refer to shown in Fig. 3 f, the base 405 of the embodiment of the present invention, be a frame-type structure, upper leading screw is opened up in upper surface
Through hole 4051, lower surface open up lower leading screw through hole 4054, bearing supporting wire thick stick are installed in two through hole；It is fixation in base lower end
Orchid 4053, the base assembly of casing is connected on the right side of itself and sequenator；Guide rail installation is provided with the sidepiece 4052 of base
Face, guide rail installation screwed hole is offered thereon.
The embodiment of the present invention carries out reciprocal transportation using feed screw nut to reagent, the control accuracy of leading screw, disclosure satisfy that examination
The delivery requirements of agent.
Refer to Fig. 4 a-4d to show, the pump valve of the embodiment of the present invention integrates tube assembly will try by the syringe needle suction pipe 507 of downside
Agent is unloaded from buffer solution box installed to be sucked in the Reagent Tube on platform assembly, and passes through the selection of fluid path control unit 502, drive control
Valve module 509 and hydraulic pump 506 are selected, and reagent is discharged into reagent cartridge, carry out sequencing reaction.
Described pump valve, which integrates tube assembly, includes pump valve integrated base plate 508, and pump valve integrated base plate 508 includes peristaltic pump
Installing plate 5011, the fixed plate 5083 being connected with peristaltic pump installing plate 5011, bottom plate 5084, it is ringent that above-mentioned each plate surrounds one
Body structure；Control valve group 509 is installed in the centre of the casing.
Pump valve integrated base plate 508 also includes being arranged on the control among sipper pore group 5085 and bottom plate on bottom plate
Valve module installing plate 5081；Peristaltic pump mounting hole 5082 is provided with peristaltic pump installing plate 5011, two wrigglings are set thereon
Pump 505；Multiple reagent pipe clamps and wire clamp 5015 are also arranged at intervals on bottom plate 5084.
Accordingly, control valve group 509 is arranged on the center section of pump valve integrated base plate 508, and hydraulic pump 506 is arranged on
The sidepiece of pump valve integrated base plate 508, fluid path control unit 502 is set in the other side；Fluid path control unit 502 passes through a folding
Bent plate 503 is isolated with fluid path part.
Pump valve assemblies are arranged in the cabinet space of multiple plate compositions, are easily installed on the diverse location of tester；
In the embodiment of the present invention, pump valve integrates tube assembly and is arranged on the upper side connecting plate of sequenator casing, and downside is installation Reagent Tube
Buffer solution box installed unload platform assembly.
In embodiments of the present invention, in order to carry out sequencing reaction to plurality of reagents, the sipper pore group 5085 on bottom plate
Multiple holes are arranged side by side, syringe needle suction pipe 507 passes through sipper pore, and the other end connects fluid path end of the Reagent Tube with corresponding control valve
Mouth connection；Pipe clamp 5013 is set on sipper pore, prevents syringe needle suction pipe from tilting.When in use, control valve control syringe needle suction pipe 507
Reagent needed for choosing, is discharged into reaction warehouse by the effect of syringe needle suction pipe 507, control valve and peristaltic pump and is reacted.
Multiple pin holes are set on plate, different reagents is selected, selection is accurate, reliable.
The embodiment of the present invention, tube assembly is integrated using pump valve, plurality of reagents can be selected simultaneously, and according to pre-
The order first set carries out sequencing reaction, and testing efficiency is high.
Incorporated by reference to shown in Fig. 4 e, two kinds of reagents are passed through simultaneously in reaction warehouse, one kind is buffer solution, and one kind is reaction reagent；
Wherein, a peristaltic pump drives buffer solution to enter from buffer solution bottle in reaction warehouse；A kind of reaction that another peristaltic pump driving determines
Reagent enters in reaction warehouse jointly with above-mentioned buffer solution mixed flow.
In order to select differential responses reagent, in the control of port of export connection one of the reagent bottle of each reaction reagent
Valve processed, each control valve are sequentially connected in series, that is, the outlet of a upper control valve connects with the entrance of next control valve.When in use,
It need to only control and open a wherein control valve, then be entered with the reagent solution that the control valve connects by pipeline in reaction warehouse.
Refer to shown in Fig. 5 a-5f, buffer solution box installed unloads the structure that platform assembly is drawing and pulling type, and reagent is set on platform
Afterwards, whole platform assembly is arranged in the casing of right side, when needing to load and unload reagent, platform is pulled out, after placing, pushed back again
Original position.
It includes carrier fluid platform 310, and in the present embodiment, it is an arm-tie with handle 3101, and shakes hands to fix
On handle plate 3102；The both sides of carrier fluid platform 310 are provided with connecting plate 311, horizontal part and the reaction liquid case of connecting plate 311
The supporting plate 4082 of lifting seat 408 connects；In the presence of reaction is with liquid case lifting seat 408, carrier fluid platform 310 moves up to pump
At syringe needle suction pipe 507 on the downside of valve integrated pipe, the control through control unit, reagent is selectively drawn.
Slide track component 312 is set between described carrier fluid platform 310 and the connecting plate 311 of both sides, and it makes carrier fluid platform
Moved along connecting plate；It includes the clamp 315 for being fixed on the sidepiece of connecting plate 311, moves and can match somebody with somebody with clamp relative to clamp 315
The slide plate stopped being closed, slide plate is fixed on the sidepiece of platform connecting plate 316, and platform connecting plate 316 is arranged on the lower end of carrier fluid platform,
It drives the movement of carrier fluid platform.
Refer to shown in Fig. 5 f, slideway 3105 is set on clamp 315, slide plate can move on slideway 3105；In clamp 315
Slip 3105 on stop aperture 3104 is set, when the projection on slide plate is plugged in stop aperture 3104, slide plate and be connected thereto
Carrier fluid platform stop motion.
Platform connecting plate 316 has identical structure with connecting plate 311, and when mounted, both reversely install；Its section is
Wedge shape, including the horizontal plane 3112 of an inclined plane and sidepiece, horizontal plane 3112 is being connected.
The buffer solution box installed of the embodiment of the present invention unloads platform assembly, is not only able to the reagent of offer demand, moreover, handling examination
Agent is convenient, saves cabinet space.
Above-mentioned detailed description is illustrating for one of them possible embodiments of the present invention, and the embodiment is simultaneously not used to
The scope of the claims of the present invention is limited, all equivalence enforcements or change without departing from carried out by the present invention, is intended to be limited solely by the technology of the present invention
In the range of scheme.
Claims (1)
1. the reagent fluid control apparatus of a kind of DNA sequencer, it is characterised in that integrate tube assembly including pump valve, it includes pump
Valve integrated base plate, pump valve integrated base plate include peristaltic pump installing plate, the fixed plate being connected with peristaltic pump installing plate, bottom plate,
The peristaltic pump installing plate, the fixed plate being connected with peristaltic pump installing plate, bottom plate surround a ringent body structure；In the case
The centre of body is provided with control valve group；
Pump valve integrated base plate also includes being arranged on the control valve group installation among sipper pore group and bottom plate on bottom plate
Plate；Accordingly, control valve group is arranged on the center section of pump valve integrated base plate, and hydraulic pump is arranged on pump valve integrated base plate
Sidepiece, the other side set fluid path control unit；
Multiple holes have been arranged side by side in sipper pore group on bottom plate, and syringe needle suction pipe passes through sipper pore, other end connection Reagent Tube and phase
The fluid path port connection for the control valve answered, the integrated tube assembly of valve are unloaded reagent from buffer solution box installed by the syringe needle suction pipe of downside flat
Suck in Reagent Tube on platform component, and selected by the selection of fluid path control unit, drive control valve module and hydraulic pump
Select, reagent is discharged into reagent cartridge, carry out sequencing reaction；
It is drawing and pulling type structure that the buffer solution box installed, which unloads platform assembly, and it includes carrier fluid platform, the both sides peace of the carrier fluid platform
Equipped with connecting plate, slide track component is set between the carrier fluid platform and the connecting plate of the both sides, it makes carrier fluid platform along connection
Plate moves；
A control valve is connected in the port of export of the reagent bottle of each reaction reagent, each control valve is sequentially connected in series, a upper control valve
Outlet connected with the entrance of next control valve；When in use, it need to only control and open a wherein control valve, then connect with the control valve
Logical reagent solution is entered in reaction warehouse by pipeline；
Peristaltic pump mounting hole is provided with described peristaltic pump installing plate, two peristaltic pumps are set thereon；Between being gone back on bottom plate
Every the multiple reagent pipe clamps of setting and wire clamp；
Described fluid path control unit is isolated by a bending plate with fluid path part；
Two kinds of reagents are passed through simultaneously in the reaction warehouse, one kind is buffer solution, and one kind is reaction reagent；Wherein, a peristaltic pump
Buffer solution is driven to enter from buffer solution bottle in reaction warehouse；A kind of reaction reagent and above-mentioned buffering that another peristaltic pump driving determines
Liquid mixed flow enters in reaction warehouse jointly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510707072.4A CN105388313B (en) | 2015-10-27 | 2015-10-27 | A kind of reagent fluid control apparatus of DNA sequencer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510707072.4A CN105388313B (en) | 2015-10-27 | 2015-10-27 | A kind of reagent fluid control apparatus of DNA sequencer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105388313A CN105388313A (en) | 2016-03-09 |
| CN105388313B true CN105388313B (en) | 2017-11-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510707072.4A Expired - Fee Related CN105388313B (en) | 2015-10-27 | 2015-10-27 | A kind of reagent fluid control apparatus of DNA sequencer |
Country Status (1)
| Country | Link |
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| CN (1) | CN105388313B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106153962B (en) * | 2016-07-22 | 2018-01-30 | 嘉兴科瑞迪医疗器械有限公司 | A kind of micro-column gel card automatic puncturing device |
| CN108949939B (en) * | 2017-05-26 | 2023-04-25 | 深圳市真迈生物科技有限公司 | Method, device and system for controlling sequence determination reaction |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201518030U (en) * | 2009-10-14 | 2010-06-30 | 北京吉天仪器有限公司 | Full automatic multi-channel multi-parameter simultaneous measuring flow injection analyzer |
| CN102236023A (en) * | 2011-03-30 | 2011-11-09 | 深圳市康立高科技有限公司 | Flowing type multi-channel biochemical analyzer |
| CN102656464A (en) * | 2009-12-22 | 2012-09-05 | 通用电气健康护理生物科学股份公司 | Method of analysis with improved mixing |
| CN102707078A (en) * | 2012-05-24 | 2012-10-03 | 中国科学院北京基因组研究所 | Reagent supply system for DNA (deoxyribonucleic acid) sequencer and control method |
| CN103954782A (en) * | 2014-04-11 | 2014-07-30 | 珠海美路得企业发展有限公司 | Biological chip detecting system |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8298763B2 (en) * | 2007-03-02 | 2012-10-30 | Lawrence Livermore National Security, Llc | Automated high-throughput flow-through real-time diagnostic system |
-
2015
- 2015-10-27 CN CN201510707072.4A patent/CN105388313B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201518030U (en) * | 2009-10-14 | 2010-06-30 | 北京吉天仪器有限公司 | Full automatic multi-channel multi-parameter simultaneous measuring flow injection analyzer |
| CN102656464A (en) * | 2009-12-22 | 2012-09-05 | 通用电气健康护理生物科学股份公司 | Method of analysis with improved mixing |
| CN102236023A (en) * | 2011-03-30 | 2011-11-09 | 深圳市康立高科技有限公司 | Flowing type multi-channel biochemical analyzer |
| CN102707078A (en) * | 2012-05-24 | 2012-10-03 | 中国科学院北京基因组研究所 | Reagent supply system for DNA (deoxyribonucleic acid) sequencer and control method |
| CN103954782A (en) * | 2014-04-11 | 2014-07-30 | 珠海美路得企业发展有限公司 | Biological chip detecting system |
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| CN105388313A (en) | 2016-03-09 |
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Granted publication date: 20171114 Termination date: 20191027 |