CN105343647A - Traditional Chinese medicine preparation for treating neurasthenia - Google Patents

Abstract

The invention provides a traditional Chinese medicine preparation for treating neurasthenia. The neurasthenia is treated by mainly taking an oral traditional Chinese medicine preparation on the basis of the principle of treatment on the neurasthenia in the traditional medicine in China, referring to the modern pharmacological study and following the traditional Chinese medicine theory. Radix scrophulariae, phellodendron bark, glossy privet fruit, cordyceps sinensis, ass-hide glue, tortoise shell, prepared rehmannia root, dogwood and balsam pear are used as monarch drugs for nourishing yin to reduce pathogenic fire, strengthening the spleen and replenishing qi, nourishing the blood and calming the nerves as well as strengthening the body resistance and eliminating the pathogenic factor so as to regulate the internal and external environments of organisms to be stable and regulate the external environment of the organisms to be coordinated and balanced; human placentae, clematis root, beefwood-like clubmoss herb, spatholobus sinensis, radix angelicae and safflower are used as ministerial drugs for soothing the liver and relieving stagnation, promoting blood circulation to remove blood stasis as well as dredging the channels; rose, bupleurum, chinaberry, chrysanthemum, bamboo shavings, rostrate lepidogrammitis herb and sanchi flower are used as auxiliary drugs for promoting the circulation of qi and relieving the depressed liver, soothing the nerves and calming as well as expelling pathogenic wind and relieving spasm; and water chestnut, sealwort, subprostrate sophora, wolfberry fruit, mulberry and Chinese yam are used as adjuvant drugs for smoothing the liver and calming the heart, strengthening the spleen and stomach, benefiting qi and blood, nourishing yin and moistening dryness as well as coordinating the heart-kidney. The traditional Chinese medicine preparation has good nourishing and invigorating effects.

Description

One treats neurasthenic Chinese medicine preparation

Technical field

The present invention relates to the medicinal preparation containing deriving from plant, animal or raw mineral materials, particularly one treats neurasthenic Chinese medicine preparation and preparation method thereof.

Background technology

Along with the fast development of Chinese society's economy, the quickening of urbanization and aged tendency of population process, and the impact of the factor such as competitiveness, unemployment, rhythm of life change, mental sickness is more and more outstanding and serious to the harm of Chinese people's health.Doctor trained in Western medicine thinks that the muscle power of over loading or mental work cause cerebral cortex excitement and inhibit feature disorder, and produces neurasthenic syndrome.The traditional Chinese medical science thinks seven emotions, that is: happiness, anger, melancholy, think of, compassion, probably, the bad emotion such as frightened can induce an illness.And modern medicine study proves: mostly neurasthenia is depression.Cause psychosis, insomnia, depression, anxiety neurosis, the various mental sickness such as schizophrenia sharply rises, and because mental sickness sickness rate increases increasingly, is called as " the stealthy killer of 21 century ".Current therapeutic mental sickness types of drugs is various, and simple western medicine has dependency, and treatment side effect is large, the time is long, and easily occurs that rank symptom of breaking even occurs serial reaction, and even needing of having takes medicine all the life, major injury hepatic and renal function, formation vicious cycle.

Summary of the invention

Technical problem to be solved by this invention is, provides that a kind of formula is simple, processing technology is easy, and the little and convenient drug administration of toxic and side effects, medicament is easy to manufacture, new drug with low cost.Inventor thinks in research practice, and primary disease is all caused by the heart, the dirty functional disorder of liver,spleen,kidney four, and The heart controls mental activities, for brain, feelings will activity president are in heart and brain, feelings will activity adjustment is liver, and liver is dredged and rushes down bar and reach, QI movement being in harmonious way, the fluent harmony of feelings will, internal organs YIN and YANG in a relative equilibrium, then all diseases not life.The present invention adopts the Chinese crude drug of different properties, has carried out scientific compatibility, and can reach desirable therapeutic effect, safety, processing technology is easy, and toxic and side effects is little, and convenient drug administration, medicament is easy to manufacture, with low cost.

One of the present invention treats neurasthenic Chinese medicine preparation, based on China's traditional medicine to neurasthenic Therapeutic Principle, with reference to modern pharmacological research, follow tcm theory, and grasping is that this principle is treated with oral traditional Chinese medicine preparation.With Radix Scrophulariae, Cortex Phellodendri, Fructus Ligustri Lucidi, Cordyceps, Colla Corii Asini, Carapax Et Plastrum Testudinis, Radix Rehmanniae Preparata, Fructus Corni, Fructus Momordicae charantiae be monarch drug nourishing YIN to lower pathogenic fire, invigorating the spleen and benefiting QI, the appropriate god that nourishes blood, strengthening vital QI to eliminate pathogenic factors reconditioner inside and outside environment stable, and body external environment coordinated balance; With Placenta Hominis, Radix Clematidis, Lycopodium casuarinoides Spring, Spatholobus sinensis chum et T. Chen., the Radix Angelicae Dahuricae, Flos Carthami for ministerial drug, control and give dispersing the stagnated live-QI to relieve the stagnation of QI, blood circulation promoting and blood stasis dispelling the meridian dredging; With Flos Rosae Rugosae, Radix Bupleuri, Fructus Toosendan, Flos Chrysanthemi, Caulis Bambusae In Taenia, Herba Lepidogrammitis rostratae, flower of Radix Notoginseng be accessory drugs promoting QI circulation for relieving depression, calmness of calming the nerves, wind dispelling spasmolytic; With Pedicellus et Pericarpium Trapae, Rhizoma Polygonati, Radix Sophorae Tonkinensis, Fructus Lycii, Fructus Mori, Rhizoma Dioscoreae for adjuvant drug soothing liver-QI mind calming, strengthening the spleen and stomach, fill blood, YIN nourishing profit is hot-tempered, and restoring normal coordination between the heart and kidney, has good nourishing benefiting action.

The property of medicine and the pharmacology of medicine selected by the present invention are respectively:

Radix Scrophulariae:

[meridian distribution of property and flavor] is bitter, sweet, salty, cold, returns lung, stomach, kidney channel;

[effect] YIN nourishing and the production of body fluid promoting, heat-clearing and toxic substances removing; Removing pathogenic heat from blood and toxic substance from the body: be suitable for heat in blood and sore; Heat enters nutrient blood, crimson tongue and doing; Intense heat in both QI and blood systems, pyretic toxicity sends out speckle; Heat falls into pericardium, unconsciousness due to high fever; Wind heat is attacked, laryngopharynx swelling and pain; Pathopyretic ulcer, red and swollen heat pain; Scrofula sucutaneous nodule; Chang Peiwu removing toxic substances and promoting subsidence of swelling eliminating stagnation medicine; Nourishing YIN to lower pathogenic fire: cure mainly yin asthenia generating intrinsic heat; Hyperactivity of fire caused by deficiency of YIN, pharyngeal swelling is spat blood, hectic fever due to YIN-deficiency consumptive fever; Consumption of YIN caused by febrile disease, dysphoria and insomnia, thirsty crimson tongue.

Cortex Phellodendri:

[meridian distribution of property and flavor] is bitter, cold.Return kidney, urinary bladder channel.

[function cures mainly] heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.

Spatholobus sinensis chum et T. Chen.:

[meridian distribution of property and flavor] is sweet, pungent, temperature; Enter Liver Channel.

[effect] promoting the circulation of blood is enriched blood, relaxing muscles and tendons and activating QI and blood in the collateral.For blood deficiency amenorrhea, menoxenia, dysmenorrhea.For diseases such as traumatic injury, numb limbs and tense tendons, soreness of waist and knee joint, rheumatic arthralgia.

Fructus Ligustri Lucidi:

[meridian distribution of property and flavor] bitter in the mouth, sweet, property is put down, and enters liver, kidney channel;

[effect] enriching yin and nourishing kidney.

Colla Corii Asini:

[nature and flavor, return through] are sweet, flat.Return lung, liver, kidney channel.

[effect] enriches blood, hemostasis, nourshing Yin and drynsessmoistening prescription.

[composition] donkey skin.Adjuvant: crystal sugar, yellow wine, Oleum Glycines.

[character] this product is rectangle or square block, and pitchy is glossy.Matter is hard and crisp, and section light, fragment is looked in brown translucent illumination.Feeble QI, taste is micro-sweet.

[function cures mainly] to be enriched blood YIN nourishing, is moisturized, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.

Carapax Et Plastrum Testudinis:

[meridian distribution of property and flavor] is salty, sweet, is slightly cold.Return liver, kidney, heart channel.

[function cures mainly] nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, reinforcing the heart of nourishing blood.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, has a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and muscles and bones flaccidity is soft, has a guilty conscience forgetful.

Radix Rehmanniae Preparata:

[meridian distribution of property and flavor] property is sweet, tepor, enters liver, kidney channel.

[effect] nourishing the blood and yin, vital essence replenishing and marrow benifiting.

Fructus Corni: property is flat, sweet in the mouth, acid, function nourishing the liver and kidney, astringing YIN to stop sweating emergency treatment of collapse, is nourishing kidney yin key medicine, is mainly used in syndrome of yin deficiency of liver and kidney, is applicable to the soreness of the waist and knees caused by Liver and kidney two void, vertigo and tinnitus, sexual impotence, seminal emission, frequent micturition, the diseases such as incessant sweating due to debility.

Fructus Momordicae charantiae:

[meridian distribution of property and flavor] is bitter, cold.Return spleen, stomach, the heart, Liver Channel.

[effect] heat clearing away is dispelled heart-fire, removing toxic substances, improving eyesight, and QI invigorating benefit essence, quenches the thirst and relieve summer heat, control carbuncle.

Placenta Hominis:

[nature and flavor] are sweet salty, warm.

[function cures mainly] QI invigorating, nourishes blood, benefit essence.The diseases such as deficient, weakness and emaciation, hemoptysis asthma, consumptive fever hectic fever due to YIN-deficiency, seminal emission.

Rhizoma Polygonati:

[nature and flavor] are sweet, flat; Return lung, spleen, kidney channel.

[function cures mainly] nourishing kidney profit spleen, invigorating the spleen and replenishing QI.Deficiency of YIN chronic cough; Xeropulmonary cough; Insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; Tinnitus order is dark; Early whitening of beard and hair; Body void is won thin; Wind favus disease.

Radix Clematidis:

[meridian distribution of property and flavor] acrid in the mouth, salty, temperature.Return urinary bladder channel.

[function cures mainly] wind-damp dispelling, the meridian dredging, expectorant Ting, the loose hypochondriac lump.Control gout, insensitive impediment, chills and pain of the waist and kness, beriberi, tetanus.

Lycopodium casuarinoides Spring:

[nature and flavor] taste is micro-sweet, temperature.

[function cures mainly] relaxing muscles and tendons to promote blood circulation, wind-damp dispelling.For rheumatic arthritis, traumatic injury, menoxenia.

The Radix Angelicae Dahuricae:

[nature and flavor] are pungent, and temperature enters lung, spleen, stomach warp;

[effect] controls headache, supraorbital bone pain, toothache, and cold-damp is suffered from abdominal pain, skin pruritus, scabies.Expelling wind and cold, understand things pain-stopping, evacuation of pus of invigorating blood circulation, granulation promoting pain relieving, dampness leukorrhagia stopping.For mastalgia, swell and ache, have a headache, have a toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.Modern pharmacological research proves that the Radix Angelicae Dahuricae also has antiinflammatory, antipyretic-antalgic, active eliminating stagnation, can be used for controlling the effects such as mammary gland caking with other Chinese Medicine and Clavicular.

Flos Carthami:

[nature and flavor] are warm in nature, acrid in the mouth.

[function cures mainly] invigorates blood circulation latus rectum, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury, be suitable for various varicosis, peripheral neuritis, blood circulation, lower limb numbness or the congestion such as livid purple.

Flos Rosae Rugosae:

[meridian distribution of property and flavor] sweet, micro-hardship, temperature.Return liver, spleen channel.

[function cures mainly] promoting QI circulation for relieving depression, and blood, pain relieving.For stomachache due to hyperactive liver-QI attacking the stomach, lack of appetite vomiting and nausea, menoxenia, falls and flutters the pain of injury.

Radix Bupleuri:

Meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, lung meridian, spleen channel.

Function: expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.

Cure mainly: cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.

Fructus Toosendan has another name called Fructus Toosendan:

[nature and flavor] are cold in nature, bitter in the mouth,

[function] is the one of qi-activating drug; Mainly enter Liver Channel, catharsis liver-heat, promoting the circulation of QI to relieve pain, have the function except damp and hot, clearing away liver-fire, pain relieving, parasite killing.But also be make efficiently without the important source material of residual hazard free of contamination novel plant class pesticide.

Flos Chrysanthemi:

There is dispelling wind, heat clearing away, improving eyesight ,effect of removing toxic substances.The disease such as primary treatment headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.Modern pharmacological research shows, Flos Chrysanthemi has treatment coronary heart disease, reduces blood pressure, prevents hyperlipidemia, antibacterial, antiviral, antiinflammatory, anti-ageing multiple pharmacologically active of waiting for a long time.

Caulis Bambusae In Taenia:

[nature and flavor] cold nature, sweet in the mouth.

[function cures mainly] removing heat-phlegm, relieves restlessness and prevents vomiting.Expectorant, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement is held under the arm for phlegm-heat cough, gallbladder fire.

Herba Lepidogrammitis rostratae:

[nature and flavor] micro-hardship; Sweet; Flat

[return through] lung; Small intestine meridian

[function cures mainly] clearing away heat and promoting diuresis; Cough-relieving; Relieving restlessness; Removing toxic substances and promoting subsidence of swelling.Main uroschesis; Drench the puckery pain of drop; Heat syndrome cough; Vexed; Skin infection swells and ache; Traumatic injury.

Flower of Radix Notoginseng:

[nature and flavor] are cool in nature, sweet in the mouth, micro-hardship.

[function] is mainly used in that heat clearing away, removing toxic substances, removing heat from blood, blood pressure lowering, tune fat, immunomodulating, blood circulation and channel invigorating, health preserving are anti-ageing, the active ingredient of anti-inflammatory analgesic action.There is significant suppressing the hyperactive liver, eliminate the phlegm, relieving asthma, sleeping, effect such as coronary dilating, antiallergic, eliminating toxin and beautifying the skin of easing pain.

Pedicellus et Pericarpium Trapae:

Property, sweet, puckery, flat, nontoxic.Sarcocarp rich in starch, in addition containing enriching glucose, protein, vitamin (B, C) etc.Have that clearing away summer-heat is antipyretic, QI invigorating stomach invigorating, only quench one's thirst, alcoholic intoxication, diuresis lactogenesis, the effect such as anticancer.Fresh Pedicellus et Pericarpium Trapae is eaten raw, heat of relieving summer heat, only excessive thirst, and vexed, the thirsty spontaneous perspiration of all summer-heat impairment of body fluid, fever of the body, inappetence person, can make dietetic therapy fruit; Pedicellus et Pericarpium Trapae prepared food is warm in nature, and gas in energy strengthening the spleen and stomach, benefit, the tired Mental fatigue of all deficiency of the spleen causing weakness of QI, body, anorexia, the meciless person of extremity should eat.Be applicable to the control of gastric ulcer, dysentery, the esophageal carcinoma, breast carcinoma, uterus carcinoma and other cancers.

Radix Sophorae Tonkinensis:

[meridian distribution of property and flavor]: bitter, cold.Enter the heart, lung, large intestine three warp;

[function] relieves inflammation or internal heat, removing toxic substances, detumescence, pain relieving.Function cures mainly: control retropharyngeal abscess, acute throat trouble, sore throat, gingival swelling and pain, dyspnea with fullness of the chest heat syndrome cough, jaundice, dysentery, haemorrhoids, and heat is swollen, tinea alba, scabies, Serpentis, worm, lyssodexis.

Fructus Lycii:

[nature and flavor] are sweet, flat, enter liver, stomach two warp, double enter lung meridian;

[function cures mainly] the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.Cure mainly: control apoplexy dizzy, asthenia, allly see blood disorder, cough blood, flaccidity, faint, contraction, disappear miasma, hinders dry, seminal emission, reddish and whitish turbid urine, beriberi, the arthroncus of knee.

Fructus Mori:

[nature and flavor] are sweet, are slightly cold; GUIXIN, liver, kidney channel.

[function cures mainly] controls hepatic and renal YIN deficiency, sends and takes off, constipation, and order is dark, tinnitus, former infections, articular instability.It is improved skin (comprising scalp) blood supply, nutrition skin, makes the effects such as the delicate and black hair of skin, and can slow down aging.Fructus Mori is that middle-aged and elderly people is healthy and strong U.S. face, antidotal good fruit and good medicine.Normal food Fructus Mori can improving eyesight, the symptom that relieving eye strain is dry and astringent.Fructus Mori has immunologic enhancement.Fructus Mori has effect of gain to spleen, has potentiation to hemolytic reaction, can prevent human body artery sclerosis, skeletal joint sclerosis, enhance metabolism; Fructus Mori can promote the growth of erythrocyte, prevents leukopenia, and has auxiliary curative effect to diseases such as treatment diabetes, anemia, hypertension, hyperlipidemia, coronary heart disease, neurasthenias.Fructus Mori has the effects such as promoting the production of body fluid to quench thirst, facilitating digestion, help defecation, and proper amount of edible can promote gastric secretion, stimulates enterokinesia and removes scorching.The traditional Chinese medical science is thought, Fructus Mori is sweet in flavor and cold in property, there is the liver and the kidney tonifying, intestine moistening of promoting the production of body fluid, the effect such as black hair improving eyesight.

Rhizoma Dioscoreae:

[nature and flavor] sweet in the mouth, property are flat, enter lung, spleen, kidney channel;

[function cures mainly] has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will are calmed the nerves, effect of life lengthening; Cure mainly that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI are dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity be weak, the red disease such as swollen, fat of frequent micturition of quenching one's thirst, seminal emission premature ejaculation, leukorrhagia nebulousurine, skin.

Cordyceps:

[nature and flavor] sweet in the mouth, property is put down.

[function] has the effect of nourishing YIN and moistening the lung, kidney invigorating and YANG supporting, so can adjust as nourishing the lung and kidney, hemostasis and phlegm, guarantor's lung, change dysentery, stop that consumptive disease is coughed etc. the food mended.Cordycep includes cordycepic acid.Vitamin B12, fat, albumen etc.Cordyceps property is sweet, Wen Ping, nontoxic, be famous strengthening by means of tonics medicine, conventional meat boiled dinner, has the effect that tonify deficiency is healthy and strong.Be applicable to treat caused spitting of blood such as insufficiency of lung-QI and deficiency of both the lung and kidney, pulmonary tuberculosis etc. or sputum mixed with blood, cough.Breathe hard, night sweat etc., also have good curative effect to impotence due to deficiency of the kidney, waist knee joint ache etc., the excellent tonic product of the person that is also oldaged physically weak.

One treats neurasthenic Chinese medicine preparation, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Scrophulariae 5-10 part, Cortex Phellodendri 5-10 part, Fructus Ligustri Lucidi 5-10 part, Colla Corii Asini 5-10 part, Carapax Et Plastrum Testudinis 5-10 part, Radix Rehmanniae Preparata 5-10 part, Fructus Corni 5-10 part, Fructus Momordicae charantiae 5-10 part, Placenta Hominis 5-10 part, Radix Clematidis 5-10 part, Lycopodium casuarinoides Spring 5-10 part, Spatholobus sinensis chum et T. Chen. 5-10 part, Radix Angelicae Dahuricae 5-10 part, Flos Carthami 5-10 part, Flos Rosae Rugosae 5-10 part, Radix Bupleuri 5-10 part, Fructus Toosendan 5-10 part, Flos Chrysanthemi 5-10 part, Caulis Bambusae In Taenia 5-10 part, Herba Lepidogrammitis rostratae 5-10 part, flower of Radix Notoginseng 5-10 part, Pedicellus et Pericarpium Trapae 5-10 part, Rhizoma Polygonati 5-10 part, Radix Sophorae Tonkinensis 5-10 part, Fructus Lycii 5-10 part, Fructus Mori 5-10 part, Rhizoma Dioscoreae 5-10 part.

One treats neurasthenic Chinese medicine preparation, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Scrophulariae 6-8 part, Cortex Phellodendri 6-8 part, Fructus Ligustri Lucidi 6-8 part, Colla Corii Asini 6-8 part, Carapax Et Plastrum Testudinis 6-8 part, Radix Rehmanniae Preparata 6-8 part, Fructus Corni 6-8 part, Fructus Momordicae charantiae 6-8 part, Placenta Hominis 6-8 part, Radix Clematidis 6-8 part, Lycopodium casuarinoides Spring 6-8 part, Spatholobus sinensis chum et T. Chen. 6-8 part, Radix Angelicae Dahuricae 6-8 part, Flos Carthami 6-8 part, Flos Rosae Rugosae 6-8 part, Radix Bupleuri 6-8 part, Fructus Toosendan 6-8 part, Flos Chrysanthemi 6-8 part, Caulis Bambusae In Taenia 6-8 part, Herba Lepidogrammitis rostratae 6-8 part, flower of Radix Notoginseng 6-8 part, Pedicellus et Pericarpium Trapae 6-8 part, Rhizoma Polygonati 6-8 part, Radix Sophorae Tonkinensis 6-8 part, Fructus Lycii 6-8 part, Fructus Mori 6-8 part, Rhizoma Dioscoreae 6-8 part.

One treats neurasthenic Chinese medicine preparation, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Scrophulariae 7 parts, Cortex Phellodendri 7 parts, Fructus Ligustri Lucidi 7 parts, 7 parts, Colla Corii Asini, Carapax Et Plastrum Testudinis 7 parts, Radix Rehmanniae Preparata 7 parts, Fructus Corni 7 parts, 7 parts, Fructus Momordicae charantiae, Placenta Hominis 7 parts, Radix Clematidis 7 parts, Lycopodium casuarinoides Spring 7 parts, Spatholobus sinensis chum et T. Chen. 7 parts, the Radix Angelicae Dahuricae 7 parts, 7 parts, Flos Carthami, Flos Rosae Rugosae 7 parts, Radix Bupleuri 7 parts, Fructus Toosendan 7 parts, Flos Chrysanthemi 7 parts, Caulis Bambusae In Taenia 7 parts, Herba Lepidogrammitis rostratae 7 parts, flower of Radix Notoginseng 7 parts, Pedicellus et Pericarpium Trapae 7 parts, Rhizoma Polygonati 7 parts, Radix Sophorae Tonkinensis 7 parts, Fructus Lycii 7 parts, 7 parts, Fructus Mori, Rhizoma Dioscoreae 7 parts.

Treat a preparation method for neurasthenic Chinese medicine preparation, it is characterized in that: described Chinese medicine preparation dosage form is that the preparation method of capsule comprises:

Step a, puts into 10 times of water gagings by formula proportion by crude drug, heating and refluxing extraction 3 times, each 45 minutes ~ 1 hour, is merged by 3 extracting solution and leaves standstill;

Step b, by above-mentioned decompression filtrate recycling ethanol and to be concentrated into liquor strength be 0.4g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.06; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicated powder, incapsulate.

Usage and consumption: every day three times, one time four, warm water delivery service one week is a course for the treatment of.

Treat a preparation method for neurasthenic Chinese medicine preparation, it is characterized in that: described Chinese medicine preparation dosage form is that the preparation method of soup potus comprises:

1, getting Carapax Et Plastrum Testudinis according to formula proportion clays into power for subsequent use;

2, by formula proportion by Radix Scrophulariae, Cortex Phellodendri, Fructus Ligustri Lucidi, Colla Corii Asini, Radix Rehmanniae Preparata, Fructus Corni, Fructus Momordicae charantiae, Placenta Hominis, Radix Clematidis, Lycopodium casuarinoides Spring, Spatholobus sinensis chum et T. Chen., the Radix Angelicae Dahuricae, Flos Carthami, Flos Rosae Rugosae, Radix Bupleuri, Fructus Toosendan, Flos Chrysanthemi, Caulis Bambusae In Taenia, Herba Lepidogrammitis rostratae, flower of Radix Notoginseng, Pedicellus et Pericarpium Trapae, Rhizoma Polygonati, Radix Sophorae Tonkinensis, Fructus Lycii, Fructus Mori, Rhizoma Dioscoreae, clean, put into marmite and boil 15-20 minute in 150-180 DEG C, extract supernatant be cooled to room temperature (boil and carry three times), get boil for three times put on clear liquid mix homogeneously after for subsequent use;

3, in proportion the extracting solution after purification and Carapax Et Plastrum Testudinis powder for subsequent use are in harmonious proportion and are evenly bottled, the disinfecting container being placed in high temperature >=100 DEG C carries out disinfection, and gets product.

Usage and dosage: each 5-10ml, taking with warm water dilution, one week is a course for the treatment of.

Detailed description of the invention:

Embodiment 1, formula: Radix Scrophulariae 5g, Cortex Phellodendri 5g, Fructus Ligustri Lucidi 5g, Colla Corii Asini 5g, Carapax Et Plastrum Testudinis 5g, Radix Rehmanniae Preparata 5g, Fructus Corni 5g, Fructus Momordicae charantiae 5g, Placenta Hominis 5g, Radix Clematidis 5g, Lycopodium casuarinoides Spring 5g, Spatholobus sinensis chum et T. Chen. 5g, Radix Angelicae Dahuricae 5g, Flos Carthami 5g, Flos Rosae Rugosae 5g, Radix Bupleuri 5g, Fructus Toosendan 5g, Flos Chrysanthemi 5g, Caulis Bambusae In Taenia 5g, Herba Lepidogrammitis rostratae 5g, flower of Radix Notoginseng 5g, Pedicellus et Pericarpium Trapae 5g, Rhizoma Polygonati 5g, Radix Sophorae Tonkinensis 5g, Fructus Lycii 5g, Fructus Mori 5g, Rhizoma Dioscoreae 5g.

Preparation method comprises:

Step a, puts into 10 times of water gagings by formula proportion by crude drug, heating and refluxing extraction 3 times, each 45 minutes ~ 1 hour, is merged by 3 extracting solution and leaves standstill;

Step b, by above-mentioned decompression filtrate recycling ethanol and to be concentrated into liquor strength be 0.4g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.06; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicated powder, incapsulate.

Usage and consumption: every day three times, one time four, warm water delivery service one week is a course for the treatment of.

Treatment model case:

Patient, 72 years old Lee is old too, is one very good to spirit in the past, an old man loquacious, becomes suddenly closely over the past half year and does not like motion, slow in one's movements stiff, little housework needs just can complete for a long time, does not also like initiatively speech, at every turn all with briefly low spoken response household.Facial expression is with low uncertainty, and eyes are stared sometimes, and trend is usually remained indifferent or apathetic to external world, and only when mentioning the my old man that she dies, just Tears sparkled in one's eyes for she, said that many things all can not do oneself, can not think how to do, brains blank out.Household thinks his heavy, thinks it is parkinson, old lady Li also often say oneself have uncomfortable, such as headache, dizziness, appetite reduction, weight loss, unable, urgent micturition frequent micturition uncomfortable in chest, tired out etc.But it is all normal for having done a lot of check result.Check through us and think that patient suffers from: depression in old age.Because old man's age is larger, we devise therapeutic scheme for the symptom of old lady Li, and by taking medicament of the present invention half a year, old lady's Li action recovers normal gradually, exchanges increase with household.Uncomfortable disappearance.

Embodiment 2, formula: Radix Scrophulariae 6g, Cortex Phellodendri 6g, Fructus Ligustri Lucidi 6g, Colla Corii Asini 6g, Carapax Et Plastrum Testudinis 6g, Radix Rehmanniae Preparata 6g, Fructus Corni 6g, Fructus Momordicae charantiae 6g, Placenta Hominis 6g, Radix Clematidis 6g, Lycopodium casuarinoides Spring 6g, Spatholobus sinensis chum et T. Chen. 6g, Radix Angelicae Dahuricae 6g, Flos Carthami 6g, Flos Rosae Rugosae 6g, Radix Bupleuri 6g, Fructus Toosendan 6g, Flos Chrysanthemi 6g, Caulis Bambusae In Taenia 6g, Herba Lepidogrammitis rostratae 6g, flower of Radix Notoginseng 6g, Pedicellus et Pericarpium Trapae 6g, Rhizoma Polygonati 6g, Radix Sophorae Tonkinensis 6g, Fructus Lycii 6g, Fructus Mori 6g, Rhizoma Dioscoreae 6g.

Preparation method comprises:

1. getting Carapax Et Plastrum Testudinis according to formula proportion clays into power for subsequent use;

2. press formula proportion by Radix Scrophulariae, Cortex Phellodendri, Fructus Ligustri Lucidi, Colla Corii Asini, Radix Rehmanniae Preparata, Fructus Corni, Fructus Momordicae charantiae, Placenta Hominis, Radix Clematidis, Lycopodium casuarinoides Spring, Spatholobus sinensis chum et T. Chen., the Radix Angelicae Dahuricae, Flos Carthami, Flos Rosae Rugosae, Radix Bupleuri, Fructus Toosendan, Flos Chrysanthemi, Caulis Bambusae In Taenia, Herba Lepidogrammitis rostratae, flower of Radix Notoginseng, Pedicellus et Pericarpium Trapae, Rhizoma Polygonati, Radix Sophorae Tonkinensis, Fructus Lycii, Fructus Mori, Rhizoma Dioscoreae, clean, put into marmite and boil 15-20 minute in 150-180 DEG C, extract supernatant be cooled to room temperature (boil and carry three times), get boil for three times put on clear liquid mix homogeneously after for subsequent use;

3. in proportion the extracting solution after purification and Carapax Et Plastrum Testudinis powder for subsequent use are in harmonious proportion and are evenly bottled, the disinfecting container being placed in high temperature >=100 DEG C carries out disinfection, and gets product.

Usage and dosage: each 5-10ml, taking with warm water dilution, one week is a course for the treatment of.

Treatment model case:

Sex: man, the age: 52 years old, has a delicate constitution, neurasthenia, and poor appetite, can't have dinner, after two courses for the treatment of of oral invention formulation, recovers normal, does not recur so far.

Embodiment 3, formula: Radix Scrophulariae 7g, Cortex Phellodendri 7g, Fructus Ligustri Lucidi 7g, Colla Corii Asini 7g, Carapax Et Plastrum Testudinis 7g, Radix Rehmanniae Preparata 7g, Fructus Corni 7g, Fructus Momordicae charantiae 7g, Placenta Hominis 7g, Radix Clematidis 7g, Lycopodium casuarinoides Spring 7g, Spatholobus sinensis chum et T. Chen. 7g, Radix Angelicae Dahuricae 7g, Flos Carthami 7g, Flos Rosae Rugosae 7g, Radix Bupleuri 7g, Fructus Toosendan 7g, Flos Chrysanthemi 7g, Caulis Bambusae In Taenia 7g, Herba Lepidogrammitis rostratae 7g, flower of Radix Notoginseng 7g, Pedicellus et Pericarpium Trapae 7g, Rhizoma Polygonati 7g, Radix Sophorae Tonkinensis 7g, Fructus Lycii 7g, Fructus Mori 7g, Rhizoma Dioscoreae 7g.

Preparation method is identical with embodiment 2.

Treatment model case: patient marquis so-and-so, women, 28 years old.In bank's work after graduating from university, bright and new beautiful before people, but bank's promotion pressure is very large, neurasthenia, usually has a sleepless night, and one to evening, lie on a bed and how also cannot sleep peacefully, almost every day is all panda eye, goes to work with large eye pouch, work also often has and makes mistakes, and poor appetite, can't have dinner, oral Chinese medicine preparation of the present invention one the symptom course for the treatment of is obviously improved, and sleep is good, and the mental status has been got well, after consolidated again a course for the treatment of, so far not recurrence.

Embodiment 4, formula: Radix Scrophulariae 8g, Cortex Phellodendri 8g, Fructus Ligustri Lucidi 8g, Colla Corii Asini 8g, Carapax Et Plastrum Testudinis 8g, Radix Rehmanniae Preparata 8g, Fructus Corni 8g, Fructus Momordicae charantiae 8g, Placenta Hominis 8g, Radix Clematidis 8g, Lycopodium casuarinoides Spring 8g, Spatholobus sinensis chum et T. Chen. 8g, Radix Angelicae Dahuricae 8g, Flos Carthami 8g, Flos Rosae Rugosae 8g, Radix Bupleuri 8g, Fructus Toosendan 8g, Flos Chrysanthemi 8g, Caulis Bambusae In Taenia 8g, Herba Lepidogrammitis rostratae 8g, flower of Radix Notoginseng 8g, Pedicellus et Pericarpium Trapae 8g, Rhizoma Polygonati 8g, Radix Sophorae Tonkinensis 8g, Fructus Lycii 8g, Fructus Mori 8g, Rhizoma Dioscoreae 8g.

Preparation method comprises:

Step a, puts into 10 times of water gagings by formula proportion by crude drug, heating and refluxing extraction 3 times, each 45 minutes ~ 1 hour, is merged by 3 extracting solution and leaves standstill;

Step b, by above-mentioned decompression filtrate recycling ethanol and to be concentrated into liquor strength be 0.4g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.06; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicated powder, incapsulate.

Usage and consumption: every day three times, one time four, warm water delivery service one week is a course for the treatment of.

Treatment model case: female Hao patient women, 37 years old, driving school staff, neurasthenia, feels fatigue throughout the year, weak, forgetful, brain is usually felt to swell, and what problem slice, thin piece brain does not have yet to have gone to hospital to clap, and doctor allows and has a good rest, treatment: oral Chinese medicine preparation of the present invention, treat patient's transference cure after 15 days, after consolidate one month again, do not recur so far.

Embodiment 5, formula:

Radix Scrophulariae 10g, Cortex Phellodendri 10g, Fructus Ligustri Lucidi 10g, Colla Corii Asini 10g, Carapax Et Plastrum Testudinis 10g, Radix Rehmanniae Preparata 10g, Fructus Corni 10g, Fructus Momordicae charantiae 10g, Placenta Hominis 10g, Radix Clematidis 10g, Lycopodium casuarinoides Spring 10g, Spatholobus sinensis chum et T. Chen. 10g, Radix Angelicae Dahuricae 10g, Flos Carthami 10g, Flos Rosae Rugosae 10g, Radix Bupleuri 10g, Fructus Toosendan 10g, Flos Chrysanthemi 10g, Caulis Bambusae In Taenia 10g, Herba Lepidogrammitis rostratae 10g, flower of Radix Notoginseng 10g, Pedicellus et Pericarpium Trapae 10g, Rhizoma Polygonati 10g, Radix Sophorae Tonkinensis 10g, Fructus Lycii 10g, Fructus Mori 10g, Rhizoma Dioscoreae 10g.

Preparation method comprises:

Step a, puts into 10 times of water gagings by formula proportion by crude drug, heating and refluxing extraction 3 times, each 45 minutes ~ 1 hour, is merged by 3 extracting solution and leaves standstill;

Step b, by above-mentioned decompression filtrate recycling ethanol and to be concentrated into liquor strength be 0.4g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.06; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicated powder, incapsulate.

Usage and consumption: every day three times, one time four, warm water delivery service one week is a course for the treatment of.

Model case: Zhang, 66 years old, is diagnosed as neurasthenia, poor sleeping quality, poor appetite, fatigue and weak, and oral Chinese medicine preparation of the present invention 20 days symptoms are obviously improved, after consolidated again one month, rehabilitation, does not recur so far.

Pharmacological toxicity is tested

1, acute toxicity test

Application mice carries out acute toxicity testing and shows: Mouse oral gavage Chinese medicine preparation of the present invention, under 488.8g crude drug/kg dosage, after administration, mice occurs that light activity reduces, 1 hours recovers normal, Continuous Observation 7 days after administration, none animal dead, its overall health of patients, diet, take the photograph water, urine and body weight increase all normal, experimental result shows: the maximum dosage-feeding of Mouse oral gavage Traditional Chinese medicine preparation capsule agent of the present invention is 488.8g crude drug/kg/d (LD50 > 488.8g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.1g crude drug/kg/d; By weighing machine, the dosis tolerata of mouse stomach Chinese medicine preparation of the present invention is 4888 times of clinical patient.Point out this medicine acute toxicity low, clinical drug safety.

2, long term toxicity test

Select SD rat, give the Chinese medicine preparation of the present invention of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive kills 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the body weight change of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology with drug withdrawal.Result of the test shows: invention formulation is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and matched group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range, without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, rat is had no significant effect in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) administration in continuous 90 days according to result of the test Chinese medicine preparation of the present invention, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.

3, animal local excitation test:

The allergic reaction on guinea pigs of invention formulation and capsule Rat-rectum medication irritation test.Result shows: skin anaphylactic test, high dose group 0.8g (medicated powder)/kg, low dose group 0.1g (medicated powder)/kg, be equivalent to 20 times, 2.5 times that intend clinical people's consumption [0.04g (medicated powder)/kg] respectively, through percutaneous drug delivery, be showed no animal and produce allergy; Rectal application irritation test high dose group 5.0g (medicated powder)/kg, low dose group 3.2g (medicated powder)/kg, be equivalent to 125,80 times that intend clinical people's consumption respectively, mucous membrane of rectum is observed all without phenomenons such as hyperemia, edema in official hour, histopathologic examination compares no significant difference with blank group, have no and occur obvious irritative response, often organize its overall health of patients of Some Animals of retention, body weight, breathing, circulation, central nervous system and extremity are movable, equal Non Apparent Abnormality reaction.

Clinical data

1 object and method

1.1 subject patient 200 examples, are divided into matched group 5O example at random, man 35 example, female 15 example, treatment group 150 example, man 90 example, female 60 example, two groups of ages all 18-80 year between.

1.2 diagnostic criterias are with reference to clinical manifestation:

Have a delicate constitution, malnutrition, lethargy, fatigue and weak, appetite reduce, sleep disorder.

1.3 Therapeutic Method treatment groups: take capsule of the present invention, natural gift three times are taken, 4 tablets/time, seven days courses for the treatment of.

Matched group: transfusion: liquid of glucose, oral multi-vitamin, the oral Western medicine of calming the nerves that composes oneself;

1.4 efficacy assessment standards (1) clinical recovery: clinical symptoms, sign disappear, functional activity recovers normal, checks that indices recovers.

(2) effective: symptom obviously alleviates.(3) effective: symptom alleviates slightly.(4) invalid: clinical symptoms, sign are without change.

I.5 statistical procedures uses SPSS12.0 software to carry out statistical analysis, and ask that mean compares employing one factor analysis of variance for each group, group is asked and compared employing between two.Inspection.P<0.05 is that difference has significance.

2 results

Matched group recovery from illness 22 example, accounts for 44%; Effective 11 examples, account for 22%; Effective 8 examples, account for 16%; No effect 9, accounts for 18%, total effective rate 82%.Treatment group recovery from illness 98 example, accounts for 65.33%; Effective 32 examples, account for 21.33%; Effective 15 examples, account for 10%; Invalid 5 examples, account for 3.33%.Total effective rate accounts for 96.66%.Significance (P<O.05) is had through checking two groups of differences.

All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (5)

1. the neurasthenic Chinese medicine preparation for the treatment of, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Scrophulariae 5-10 part, Cortex Phellodendri 5-10 part, Fructus Ligustri Lucidi 5-10 part, Colla Corii Asini 5-10 part, Carapax Et Plastrum Testudinis 5-10 part, Radix Rehmanniae Preparata 5-10 part, Fructus Corni 5-10 part, Fructus Momordicae charantiae 5-10 part, Placenta Hominis 5-10 part, Radix Clematidis 5-10 part, Lycopodium casuarinoides Spring 5-10 part, Spatholobus sinensis chum et T. Chen. 5-10 part, Radix Angelicae Dahuricae 5-10 part, Flos Carthami 5-10 part, Flos Rosae Rugosae 5-10 part, Radix Bupleuri 5-10 part, Fructus Toosendan 5-10 part, Flos Chrysanthemi 5-10 part, Caulis Bambusae In Taenia 5-10 part, Herba Lepidogrammitis rostratae 5-10 part, flower of Radix Notoginseng 5-10 part, Pedicellus et Pericarpium Trapae 5-10 part, Rhizoma Polygonati 5-10 part, Radix Sophorae Tonkinensis 5-10 part, Fructus Lycii 5-10 part, Fructus Mori 5-10 part, Rhizoma Dioscoreae 5-10 part.

2. one according to claim 1 treats neurasthenic Chinese medicine preparation, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Scrophulariae 6-8 part, Cortex Phellodendri 6-8 part, Fructus Ligustri Lucidi 6-8 part, Colla Corii Asini 6-8 part, Carapax Et Plastrum Testudinis 6-8 part, Radix Rehmanniae Preparata 6-8 part, Fructus Corni 6-8 part, Fructus Momordicae charantiae 6-8 part, Placenta Hominis 6-8 part, Radix Clematidis 6-8 part, Lycopodium casuarinoides Spring 6-8 part, Spatholobus sinensis chum et T. Chen. 6-8 part, Radix Angelicae Dahuricae 6-8 part, Flos Carthami 6-8 part, Flos Rosae Rugosae 6-8 part, Radix Bupleuri 6-8 part, Fructus Toosendan 6-8 part, Flos Chrysanthemi 6-8 part, Caulis Bambusae In Taenia 6-8 part, Herba Lepidogrammitis rostratae 6-8 part, flower of Radix Notoginseng 6-8 part, Pedicellus et Pericarpium Trapae 6-8 part, Rhizoma Polygonati 6-8 part, Radix Sophorae Tonkinensis 6-8 part, Fructus Lycii 6-8 part, Fructus Mori 6-8 part, Rhizoma Dioscoreae 6-8 part.

3. one according to claim 1 treats neurasthenic Chinese medicine preparation, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Scrophulariae 7 parts, Cortex Phellodendri 7 parts, Fructus Ligustri Lucidi 7 parts, 7 parts, Colla Corii Asini, Carapax Et Plastrum Testudinis 7 parts, Radix Rehmanniae Preparata 7 parts, Fructus Corni 7 parts, 7 parts, Fructus Momordicae charantiae, Placenta Hominis 7 parts, Radix Clematidis 7 parts, Lycopodium casuarinoides Spring 7 parts, Spatholobus sinensis chum et T. Chen. 7 parts, the Radix Angelicae Dahuricae 7 parts, 7 parts, Flos Carthami, Flos Rosae Rugosae 7 parts, Radix Bupleuri 7 parts, Fructus Toosendan 7 parts, Flos Chrysanthemi 7 parts, Caulis Bambusae In Taenia 7 parts, Herba Lepidogrammitis rostratae 7 parts, flower of Radix Notoginseng 7 parts, Pedicellus et Pericarpium Trapae 7 parts, Rhizoma Polygonati 7 parts, Radix Sophorae Tonkinensis 7 parts, Fructus Lycii 7 parts, 7 parts, Fructus Mori, Rhizoma Dioscoreae 7 parts.

4. a kind of preparation method for the treatment of neurasthenic Chinese medicine preparation according to claim 1-3 any one, is characterized in that: described Chinese medicine preparation dosage form is that the preparation method of capsule comprises:

Step a, puts into 10 times of water gagings by formula proportion by crude drug, heating and refluxing extraction 3 times, each 45 minutes ~ 1 hour, is merged by 3 extracting solution and leaves standstill;

Step b, by above-mentioned decompression filtrate recycling ethanol and to be concentrated into liquor strength be 0.4g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.06; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicated powder, incapsulate.

5. a kind of preparation method for the treatment of neurasthenic Chinese medicine preparation according to claim 1-3 any one, is characterized in that: described Chinese medicine preparation dosage form is that the preparation method of soup potus comprises:

1. getting Carapax Et Plastrum Testudinis according to formula proportion clays into power for subsequent use;

2. press formula proportion by Radix Scrophulariae, Cortex Phellodendri, Fructus Ligustri Lucidi, Colla Corii Asini, Radix Rehmanniae Preparata, Fructus Corni, Fructus Momordicae charantiae, Placenta Hominis, Radix Clematidis, Lycopodium casuarinoides Spring, Spatholobus sinensis chum et T. Chen., the Radix Angelicae Dahuricae, Flos Carthami, Flos Rosae Rugosae, Radix Bupleuri, Fructus Toosendan, Flos Chrysanthemi, Caulis Bambusae In Taenia, Herba Lepidogrammitis rostratae, flower of Radix Notoginseng, Pedicellus et Pericarpium Trapae, Rhizoma Polygonati, Radix Sophorae Tonkinensis, Fructus Lycii, Fructus Mori, Rhizoma Dioscoreae, clean, put into marmite and boil 15-20 minute in 150-180 DEG C, extract supernatant be cooled to room temperature (boil and carry three times), get boil for three times put on clear liquid mix homogeneously after for subsequent use;

3. in proportion the extracting solution after purification and Carapax Et Plastrum Testudinis powder for subsequent use are in harmonious proportion and are evenly bottled, the disinfecting container being placed in high temperature >=100 DEG C carries out disinfection, and gets product.