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CN104547562A - Medicine for treating pulmonary tuberculosis and preparation method thereof - Google Patents

Medicine for treating pulmonary tuberculosis and preparation method thereof Download PDF

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Publication number
CN104547562A
CN104547562A CN201410739993.4A CN201410739993A CN104547562A CN 104547562 A CN104547562 A CN 104547562A CN 201410739993 A CN201410739993 A CN 201410739993A CN 104547562 A CN104547562 A CN 104547562A
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parts
medicine
rhizoma
radix
bletillae
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张仁勇
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
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    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835Aquilaria
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
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Abstract

The invention discloses a medicine for treating pulmonary tuberculosis and a preparation method thereof. The medicine is prepared from the following medicinal raw materials in parts by weight: 8-15 parts of asparagus fern, 12-18 parts of radix ophiopogonis, 10-15 parts of selfheal, 15-20 parts of spreading hedyotis herb, 30-50 parts of astragalus membranaceus, 15-25 parts of agarwood, 3-5 parts of licorice root, 12-18 parts of angelica sinensis, 15-25 parts of fritillaria cirrhosa, 8-15 parts of pericarpium citri reticulatae, 12-18 parts of apricot kernel, 15-20 parts of poria cocos, 7-15 parts of rhizoma atractylodis macrocephalae, 8-12 parts of ligusticum wallichii, 15-20 parts of cortex mori radicis, 15-25 parts of schisandra chinensis, 8-15 parts of pinellia ternate, 12-20 parts of bletilla striata, 8-15 parts of rhizoma anemarrhenae, 7-15 parts of endothelium corneum gigeriae galli and 3-8 parts of Chinese azalea flower. The raw materials are taken according to the weight proportion, washed, dried, sterilized and grinded to prepare the medicine. The medicine has the characteristics of quick response, good curative effect and small side effect. The medicine is applied to 156 cases in clinical application, the total effective rate is 95.5 percent, and the medicine is convenient and quick to use.

Description

One treats phthisical medicine and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of preparation method for the treatment of phthisical medicine and this medicine.
Background technology
Pulmonary tuberculosis ( pulmonary tuberculosis PTB) be the pneumonia infection disease caused by mycobacterium tuberculosis.It is the disease of serious threat human health.The lunger of the source of infection of mycobacterium tuberculosis (be called for short tulase, lower with) mainly discharge of bacteria, passes through respiratory infectious.Healthy People infects tulase and might not fall ill, and only just falls ill when immunity of organisms declines.The World Health Organization's statistics shows, tuberculosis 800 ~ 1,000 ten thousand occurs every year in the whole world, about has 3,000,000 people to die from tuberculosis every year, is the single infectious disease that the number of causing death is maximum.Within 1993, WHO announces " the global tuberculosis state of emergency ", thinks that tuberculosis has become the important public health problem in the whole world.China is one of country that tuberculosis epidemic situation is the most serious in the world.
Pulmonary tuberculosis is divided into primary pulmonary tuberculosis (I type), hematogenous disseminated pulmonary tuberculosis (II type), infiltrative pulmonary tuberculosis (type III), slowfiber cavernous pulmonary tuberculosis (IV type), tuberculous pleuritis (V-type) etc.
China Patent Publication No. is disclose in the file of CN103142860A " one treats phthisical Miao Ethnomedicine ", and this Miao Ethnomedicine is formulated by 4 taste medical materials, and its quality proportioning is: Radix orixae japonicae 20-25, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-15, Radix seu Herba Spiranthis Lanceae 10-15, Spica Prunellae 15-20.
China Patent Publication No. is that the file of CN1824175A discloses " one treats phthisical Chinese medicine preparation ", and said preparation is made up of Herba Andrographis, Herba Bulbophylli Odoratissim, Herba Tripterospermi japonici, Rhizoma Seu Herba Bergeniae, Spica Prunellae, Herba Lysionoti carnosae, cantonese fairy bells, Herba Houttuyniae, Radix Osbeckiae Crinitae, Rhizoma Iridis Tectori and Rhizoma Bistortae, root of couch grass, Radix Sanguisorbae, Herba Plantaginis etc.
Preceding solution all relates to the Chinese medicine formula for the treatment of pulmonary tuberculosis disease, and in addition, treatment pulmonary tuberculosis mostly adopts western medicine at present, and the course for the treatment of is long, and greatly, relapse rate is high and patient may be made drug resistant in side effect.
Summary of the invention
The object of the invention is to the phthisical medicine for the treatment of that open a kind of rapid-action, good effect, side effect are little.
Another object of the present invention is to the preparation method that the phthisical medicine of this treatment is provided.
One of the present invention treats phthisical medicine, is obtained by the crude drug of following weight proportioning:
Radix Asparagi 8-15 part, Radix Ophiopogonis 12-18 part, Spica Prunellae 10-15 part, Herba Hedyotidis Diffusae 15-20 part, Radix Astragali 30-50 part, Lignum Aquilariae Resinatum 15-25 part, Radix Glycyrrhizae 3-5 part, Radix Angelicae Sinensis 12-18 part, Bulbus Fritillariae Cirrhosae 15-25 part, Pericarpium Citri Reticulatae 8-15 part, Semen Armeniacae Amarum 12-18 part, Poria 15-20 part, Rhizoma Atractylodis Macrocephalae 7-15 part, Rhizoma Chuanxiong 8-12 part, Cortex Mori 15-20 part, Fructus Schisandrae Chinensis 15-25 part, Rhizoma Pinelliae 8-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 12-20 part, Rhizoma Anemarrhenae 8-15 part, Endothelium Corneum Gigeriae Galli 7-15 part, Flos Rhododendri Mollis 3-8 part.
The preferred weight proportioning of above-mentioned each crude drug is:
Radix Asparagi 12 parts, Radix Ophiopogonis 14 parts, Spica Prunellae 13 parts, Herba Hedyotidis Diffusae 17 parts, the Radix Astragali 40 parts, Lignum Aquilariae Resinatum 20 parts, 4 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 15 parts, Bulbus Fritillariae Cirrhosae 20 parts, Pericarpium Citri Reticulatae 12 parts, 14 parts, Semen Armeniacae Amarum, 17 parts, Poria, the Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Chuanxiong 10 parts, Cortex Mori 17 parts, Fructus Schisandrae Chinensis 20 parts, the Rhizoma Pinelliae 12 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 17 parts, the Rhizoma Anemarrhenae 13 parts, Endothelium Corneum Gigeriae Galli 13 parts, Flos Rhododendri Mollis 6 parts.
One of the present invention treats phthisical medicine, and wherein, conventional concocting method is adopted in the process of preparing Chinese medicine of each crude drug.
A kind of preparation method for the treatment of phthisical medicine of the present invention, comprises the following steps:
(1) screen crude drug, sample by weight ratio, cleaning, dry, sterilization;
(2) pulverize, cross 800-1000 mesh sieve, mix homogeneously.
The present invention compared with prior art, there is obvious beneficial effect, as can be known from the above technical solutions: the present invention selects Radix Asparagi, Radix Ophiopogonis, Spica Prunellae, Herba Hedyotidis Diffusae, the Radix Astragali, Lignum Aquilariae Resinatum, Radix Glycyrrhizae, Radix Angelicae Sinensis, Bulbus Fritillariae Cirrhosae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Chuanxiong, Cortex Mori, Fructus Schisandrae Chinensis, the Rhizoma Pinelliae, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Rhizoma Anemarrhenae, Endothelium Corneum Gigeriae Galli and Flos Rhododendri Mollis crude drug, treat pulmonary tuberculosis by the synergism of each medicine, therapeutic effect is good.Its expense is low, rapid-action, good effect, side effect is little, relapse rate is low, and medication is convenient and swift.Clinical totally 156 examples use, and the average effectiveness level for the treatment of aforementioned disorders is 95.5%.
Detailed description of the invention
The beneficial effect of medicine of the present invention is set forth further below by way of test example.
test example:the clinical observation of medicine of the present invention
Clinical data:
All cases 156 example, wherein, male 81 example, women 75 example, max age 72 years old, minimal ages 15 years old, 28 years old mean age.
Diagnostic criteria:
" disease of tcm Standardization of diagnosis and curative effect "
Therapeutic Method:
Oral drug powder of the present invention, every day 3 times, each 5g, 1 course for the treatment of on the 10th, 1-4 the course for the treatment of.
Criterion of therapeutical effect:
Effective: transference cure
Effective: symptom is obviously alleviated
Invalid: symptom is without improvement or increase the weight of.
Therapeutic outcome:
156 routine lungers use medicine of the present invention, effective 121 examples, effective 28 examples, invalid 7 examples; Obvious effective rate 77.5%, total effective rate 95.5%.
embodiment 1
One treats phthisical medicine, comprises the following steps:
(1) screen crude drug, take Radix Asparagi 8g, Radix Ophiopogonis 12g, Spica Prunellae 10g, Herba Hedyotidis Diffusae 15g, Radix Astragali 30g, Lignum Aquilariae Resinatum 15g, Radix Glycyrrhizae 3g, Radix Angelicae Sinensis 12g, Bulbus Fritillariae Cirrhosae 15g, Pericarpium Citri Reticulatae 8g, Semen Armeniacae Amarum 12g, Poria 15g, Rhizoma Atractylodis Macrocephalae 7g, Rhizoma Chuanxiong 8g, Cortex Mori 15g, Fructus Schisandrae Chinensis 15g, Rhizoma Pinelliae 8g, Pseudobulbus Bletillae (Rhizoma Bletillae) 12g, Rhizoma Anemarrhenae 8g, Endothelium Corneum Gigeriae Galli 7g, Flos Rhododendri Mollis 3g, cleaning, dry, sterilization;
(2) pulverize, cross 800 mesh sieves, mix homogeneously.
embodiment 2
One treats phthisical medicine, comprises the following steps:
(1) screen crude drug, take Radix Asparagi 15g, Radix Ophiopogonis 18g, Spica Prunellae 15g, Herba Hedyotidis Diffusae 20g, Radix Astragali 50g, Lignum Aquilariae Resinatum 25g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 18g, Bulbus Fritillariae Cirrhosae 25g, Pericarpium Citri Reticulatae 15g, Semen Armeniacae Amarum 18g, Poria 20g, Rhizoma Atractylodis Macrocephalae 15g, Rhizoma Chuanxiong 12g, Cortex Mori 20g, Fructus Schisandrae Chinensis 25g, Rhizoma Pinelliae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Rhizoma Anemarrhenae 15g, Endothelium Corneum Gigeriae Galli 15g, Flos Rhododendri Mollis 8g, cleaning, dry, sterilization;
(2) pulverize, cross 1000 mesh sieves, mix homogeneously.
embodiment 3
One treats phthisical medicine, comprises the following steps:
(1) screen crude drug, take Radix Asparagi 12g, Radix Ophiopogonis 14g, Spica Prunellae 13g, Herba Hedyotidis Diffusae 17g, Radix Astragali 40g, Lignum Aquilariae Resinatum 20g, Radix Glycyrrhizae 4g, Radix Angelicae Sinensis 15g, Bulbus Fritillariae Cirrhosae 20g, Pericarpium Citri Reticulatae 12g, Semen Armeniacae Amarum 14g, Poria 17g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Chuanxiong 10g, Cortex Mori 17g, Fructus Schisandrae Chinensis 20g, Rhizoma Pinelliae 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 17g, Rhizoma Anemarrhenae 13g, Endothelium Corneum Gigeriae Galli 13g, Flos Rhododendri Mollis 6g, cleaning, dry, sterilization;
(2) pulverize, cross 900 mesh sieves, mix homogeneously.
The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, anyly do not depart from technical solution of the present invention content, the any simple modification done above embodiment according to technical spirit of the present invention, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.

Claims (3)

1. treat a phthisical medicine, obtained by the crude drug of following weight proportioning: Radix Asparagi 8-15 part, Radix Ophiopogonis 12-18 part, Spica Prunellae 10-15 part, Herba Hedyotidis Diffusae 15-20 part, Radix Astragali 30-50 part, Lignum Aquilariae Resinatum 15-25 part, Radix Glycyrrhizae 3-5 part, Radix Angelicae Sinensis 12-18 part, Bulbus Fritillariae Cirrhosae 15-25 part, Pericarpium Citri Reticulatae 8-15 part, Semen Armeniacae Amarum 12-18 part, Poria 15-20 part, Rhizoma Atractylodis Macrocephalae 7-15 part, Rhizoma Chuanxiong 8-12 part, Cortex Mori 15-20 part, Fructus Schisandrae Chinensis 15-25 part, Rhizoma Pinelliae 8-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 12-20 part, Rhizoma Anemarrhenae 8-15 part, Endothelium Corneum Gigeriae Galli 7-15 part, Flos Rhododendri Mollis 3-8 part.
2. one as claimed in claim 1 treats phthisical medicine, it is characterized in that: obtained by the crude drug of following weight proportioning: Radix Asparagi 12 parts, Radix Ophiopogonis 14 parts, Spica Prunellae 13 parts, Herba Hedyotidis Diffusae 17 parts, the Radix Astragali 40 parts, Lignum Aquilariae Resinatum 20 parts, 4 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 15 parts, Bulbus Fritillariae Cirrhosae 20 parts, Pericarpium Citri Reticulatae 12 parts, 14 parts, Semen Armeniacae Amarum, 17 parts, Poria, the Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Chuanxiong 10 parts, Cortex Mori 17 parts, Fructus Schisandrae Chinensis 20 parts, the Rhizoma Pinelliae 12 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 17 parts, the Rhizoma Anemarrhenae 13 parts, Endothelium Corneum Gigeriae Galli 13 parts, Flos Rhododendri Mollis 6 parts.
3. a kind of preparation method for the treatment of phthisical medicine as claimed in claim 1 or 2, comprises the following steps:
(1) screen crude drug, sample by weight ratio, cleaning, dry, sterilization;
(2) pulverize, cross 800-1000 mesh sieve, mix homogeneously.
CN201410739993.4A 2014-12-08 2014-12-08 Medicine for treating pulmonary tuberculosis and preparation method thereof Pending CN104547562A (en)

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Application publication date: 20150429