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CN104547562A - 一种治疗肺结核的药物及其制备方法 - Google Patents

一种治疗肺结核的药物及其制备方法 Download PDF

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CN104547562A
CN104547562A CN201410739993.4A CN201410739993A CN104547562A CN 104547562 A CN104547562 A CN 104547562A CN 201410739993 A CN201410739993 A CN 201410739993A CN 104547562 A CN104547562 A CN 104547562A
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张仁勇
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Abstract

本发明公开了一种治疗肺结核的药物及其制备方法，由下述重量配比的原料药制得：天冬8-15份，麦冬12-18份，夏枯草10-15份，白花蛇舌草15-20份，黄芪30-50份，沉香15-25份，甘草3-5份，当归12-18份，川贝15-25份，陈皮8-15份，杏仁12-18份，茯苓15-20份，白术7-15份，川芎8-12份，桑白皮15-20份，五味子15-25份，半夏8-15份，白芨12-20份，知母8-15份，鸡内金7-15份，闹羊花3-8份。将上述各原料药按重量配比取样，清洗、干燥、消毒、粉碎即得。本发明药物具有起效快、疗效好、副作用小的特点。临床共156例使用，总有效率为95.5%，且用药方便快捷。

Description

一种治疗肺结核的药物及其制备方法
技术领域
本发明属于中药领域，具体涉及一种治疗肺结核的药物及该药物的制备方法。
背景技术
肺结核（pulmonary tuberculosis PTB）是由结核分枝杆菌引发的肺部感染性疾病。是严重威胁人类健康的疾病。结核分枝杆菌（简称结核菌，下同）的传染源主要是排菌的肺结核患者，通过呼吸道传播。健康人感染结核菌并不一定发病，只有在机体免疫力下降时才发病。世界卫生组织（WHO）统计表明，全世界每年发生结核病800～1000万，每年约有300万人死于结核病，是造成死亡人数最多的单一传染病。1993年WHO宣布“全球结核病紧急状态”， 认为结核病已成为全世界重要的公共卫生问题。我国是世界上结核疫情最严重的国家之一。
肺结核分为原发性肺结核（I型）、血行播散型肺结核（II型），浸润型肺结核（III型），慢纤维空洞型肺结核（IV型）、结核性胸膜炎（V型）等。
中国专利公开号为CN103142860A的文件中公开了“一种治疗肺结核的苗药”，该苗药由4味药材配制而成，其质量配比为:臭山羊20-25，白芨10-15，盘龙参10-15，夏枯草15-20。
中国专利公开号为CN1824175A的文件公开了“一种治疗肺结核的中药制剂”，该制剂由穿心莲、果上叶、青鱼胆草、岩白菜、夏枯草、岩豇豆、万寿竹、鱼腥草、朝天罐、鸢尾及拳参、茅草根、地榆、车前草等组成。
前述技术方案均涉及治疗肺结核病症的中药配方，除此之外，治疗肺结核目前大都采用西药治疗，疗程长，副作用大，复发率高且可能使患者对药物产生耐药性。
发明内容
本发明的目的在于公开一种起效快、疗效好、副作用小的治疗肺结核的药物。
本发明的另一目的在于提供该治疗肺结核的药物的制备方法。
本发明的一种治疗肺结核的药物，由下述重量配比的原料药制得：
天冬8-15份，麦冬12-18份，夏枯草10-15份，白花蛇舌草15-20份，黄芪30-50份，沉香15-25份，甘草3-5份，当归12-18份，川贝15-25份，陈皮8-15份，杏仁12-18份，茯苓15-20份，白术7-15份，川芎8-12份，桑白皮15-20份，五味子15-25份，半夏8-15份，白芨12-20份，知母8-15份，鸡内金7-15份，闹羊花3-8份。
上述各原料药的优选重量配比为：
天冬12份，麦冬14份，夏枯草13份，白花蛇舌草17份，黄芪40份，沉香20份，甘草4份，当归15份，川贝20份，陈皮12份，杏仁14份，茯苓17份，白术12份，川芎10份，桑白皮17份，五味子20份，半夏12份，白芨17份，知母13份，鸡内金13份，闹羊花6份。
本发明的一种治疗肺结核的药物，其中，各原料药的炮制采常规炮制方法。
本发明的一种治疗肺结核的药物的制备方法，包括以下步骤：
（1）筛选原料药，按重量配比取样，清洗、干燥、消毒；
（2）粉碎，过800-1000目筛，混合均匀即可。
本发明与现有技术相比，具有明显的有益效果，从以上技术方案可知：本发明选用天冬、麦冬、夏枯草、白花蛇舌草、黄芪、沉香、甘草、当归、川贝、陈皮、杏仁、茯苓、白术、川芎、桑白皮、五味子、半夏、白芨、知母、鸡内金及闹羊花原料药，通过各药物的协同作用来治疗肺结核，治疗效果佳。其费用低、起效快、疗效好、副作用小、复发率低，且用药方便快捷。临床共156例使用，治疗前述病症的平均有效率为95.5%。
具体实施方式
以下通过试验例来进一步阐述本发明所述药物的有益效果。
试验例：本发明药物的临床观察
临床资料：
全部病例156例，其中，男性81例，女性75例，最大年龄72岁，最小年龄15岁，平均年龄28岁。
诊断标准：
《中医病症诊断疗效标准》
治疗方法：
口服本发明药物散剂，每日3次，每次5g，10日1个疗程，1-4个疗程即可。
 疗效标准：
显效：症状消失
有效：症状明显缓解
无效：症状无改善或加重。
治疗结果：
156例肺结核患者使用本发明药物，显效121例，有效28例，无效7例；显效率77.5%,总有效率95.5%。
实施例1
一种治疗肺结核的药物，包括以下步骤：
（1）筛选原料药，称取天冬8g，麦冬12g，夏枯草10g，白花蛇舌草15g，黄芪30g，沉香15g，甘草3g，当归12g，川贝15g，陈皮8g，杏仁12g，茯苓15g，白术7g，川芎8g，桑白皮15g，五味子15g，半夏8g，白芨12g，知母8g，鸡内金7g，闹羊花3g，清洗、干燥、消毒；
（2）粉碎，过800目筛，混合均匀即可。
实施例2
一种治疗肺结核的药物，包括以下步骤：
（1）筛选原料药，称取天冬15g，麦冬18g，夏枯草15g，白花蛇舌草20g，黄芪50g，沉香25g，甘草5g，当归18g，川贝25g，陈皮15g，杏仁18g，茯苓20g，白术15g，川芎12g，桑白皮20g，五味子25g，半夏15g，白芨20g，知母15g，鸡内金15g，闹羊花8g，清洗、干燥、消毒；
（2）粉碎，过1000目筛，混合均匀即可。
实施例3
一种治疗肺结核的药物，包括以下步骤：
（1）筛选原料药，称取天冬12g，麦冬14g，夏枯草13g，白花蛇舌草17g，黄芪40g，沉香20g，甘草4g，当归15g，川贝20g，陈皮12g，杏仁14g，茯苓17g，白术12g，川芎10g，桑白皮17g，五味子20g，半夏12g，白芨17g，知母13g，鸡内金13g，闹羊花6g，清洗、干燥、消毒；
（2）粉碎，过900目筛，混合均匀即可。
以上所述，仅是本发明的较佳实施例而已，并非对本发明作任何形式上的限制，任何未脱离本发明技术方案内容，依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与修饰，均仍属于本发明技术方案的范围内。

Claims (3)

1.一种治疗肺结核的药物，由下述重量配比的原料药制得：天冬8-15份，麦冬12-18份，夏枯草10-15份，白花蛇舌草15-20份，黄芪30-50份，沉香15-25份，甘草3-5份，当归12-18份，川贝15-25份，陈皮8-15份，杏仁12-18份，茯苓15-20份，白术7-15份，川芎8-12份，桑白皮15-20份，五味子15-25份，半夏8-15份，白芨12-20份，知母8-15份，鸡内金7-15份，闹羊花3-8份。
2.如权利要求1所述的一种治疗肺结核的药物，其特征在于：由下述重量配比的原料药制得：天冬12份，麦冬14份，夏枯草13份，白花蛇舌草17份，黄芪40份，沉香20份，甘草4份，当归15份，川贝20份，陈皮12份，杏仁14份，茯苓17份，白术12份，川芎10份，桑白皮17份，五味子20份，半夏12份，白芨17份，知母13份，鸡内金13份，闹羊花6份。
3.如权利要求1或2所述的一种治疗肺结核的药物的制备方法，包括以下步骤：
（1）筛选原料药，按重量配比取样，清洗、干燥、消毒；
（2）粉碎，过800-1000目筛，混合均匀即可。
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