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CN104288476A - Buccal tablets for preventing altitude stress and preparation method thereof - Google Patents

Buccal tablets for preventing altitude stress and preparation method thereof Download PDF

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Publication number
CN104288476A
CN104288476A CN201410590331.5A CN201410590331A CN104288476A CN 104288476 A CN104288476 A CN 104288476A CN 201410590331 A CN201410590331 A CN 201410590331A CN 104288476 A CN104288476 A CN 104288476A
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parts
fructus
radix
hours
ethanol
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苗娥
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    • A61K36/185—Magnoliopsida (dicotyledons)
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Abstract

The invention relates to buccal tablets for preventing altitude stress and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine. The buccal tablets for preventing altitude stress comprises the following raw materials in parts by weight: 10-20 parts of rhodiola rosea, 8-15 parts of snow lotus herb, 3-8 parts of Chinese wolfberries, 6-10 parts of stigma croci, 3-7 parts of santalum album, 2-6 parts of lignum dalbergiae odoriferae, 2-6 parts of clove, 3-7 parts of fructus phyllanthi, 2-9 parts of strawberries, 5-11 parts of alpine radix codonopsis, 2-7 parts of radix glycyrrhizae, 3-5 parts of calculus bovis, 4-8 parts of moschus and 2-6 parts of indigo naturalis. According to the buccal tablets for preventing altitude stress provided by the invention, the various components supplement each other and are reasonable in compatibility, so that the buccal tablets can quickly eliminate symptoms of altitude stress, have the characteristics of having obvious curative effect, taking effect quickly and being not easy to relapse and is remarkable in curative effect in remitting symptoms of headache, palpitation, anhelation, appetite loss, lassitude, lack of power, dizziness, nausea, emesis and the like.

Description

A kind of buccal tablet preventing altitude sickness and preparation method thereof
 
Technical field
The present invention relates to a kind of buccal tablet preventing altitude sickness and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Altitude sickness, i.e. altitude sickness, refer to enter rapidly more than 3000 meters highlandss without the people of adaptive training, because partial pressure of oxygen in atmospheric pressure reduces, body reduces low-oxygen environment toleration, is difficult to adapt to and cause anoxia, causes a series of altitude maladjustment thus.The symptom of altitude sickness generally shows as: bitterly, nervous, tachypnea, loss of appetite, asthenia, weak, dizzy, Nausea and vomiting, abdominal distention, diarrhoea, pain uncomfortable in chest, insomnia, dim eyesight, drowsiness, dizzy, numb hand and foot, tic etc.Sign is increased heart rate, exaggerated respiration, blood pressure mile abnormality, face or edema of the limbs, die Blausucht etc.The poisonous side effect of medicine of the prevention altitude sickness of selling in the market is large, takes in advance and can cause excitatory state to human body, and effect is not remarkable.
Summary of the invention
The object of the invention is to solve the weak point that above-mentioned prior art exists, provide a kind of therapeutic effect significantly, the buccal tablet of the prevention altitude sickness of instant effect and preparation method thereof.
The present invention is achieved by the following technical solutions:
A kind of buccal tablet preventing altitude sickness, its special character is to be made up of following raw material by weight ratio: Radix Rhodiolae 10-20 part, Herba Saussureae Involueratae 8-15 part, Fructus Lycii 3-8 part, Stigma Croci 6-10 part, Lignum Santali Albi 3-7 part, Lignum Dalbergiae Odoriferae 2-6 part, Flos Caryophylli 2-6 part, Fructus Phyllanthi 3-7 part, Fructus Fragariae Ananssae 2-9 part, high mountain Radix Codonopsis 5-11 part, Radix Glycyrrhizae 2-7 part, Calculus Bovis 3-5 part, Moschus 4-8 part, Medulla Tetrapanacis 4-8 part, Radix Sophorae Tonkinensis 3-7 part, Rhizoma Belamcandae 4-8 part, Bulbus Fritillariae Thunbergii 4-8 part, Indigo Naturalis 2-6 part, Poria 2-6 part, Fructus Kochiae 2-6 part, Fructus Crataegi 5-12 part, steviosin 3-8 part, citric acid 3-8 part, Oleum menthae 4-9 part, cane sugar powder 8-18 part, ethanol 20-30 part, water 30-50 part,
Described a kind of buccal tablet preventing altitude sickness, is made up of the raw material of following optimal proportion by weight: Radix Rhodiolae 12 parts, Herba Saussureae Involueratae 12 parts, Fructus Lycii 5 parts, Stigma Croci 7 parts, 4 parts, Lignum Santali Albi, Lignum Dalbergiae Odoriferae 2 parts, Flos Caryophylli 2 parts, Fructus Phyllanthi 4 parts, Fructus Fragariae Ananssae 5 parts, high mountain Radix Codonopsis 8 parts, 3 parts, Radix Glycyrrhizae, Calculus Bovis 4 parts, 6 parts, Moschus, Medulla Tetrapanacis 6 parts, Radix Sophorae Tonkinensis 6 parts, Rhizoma Belamcandae 6 parts, Bulbus Fritillariae Thunbergii 6 parts, Indigo Naturalis 5 parts, 5 parts, Poria, the Fructus Kochiae 5 parts, Fructus Crataegi 8 parts, steviosin 4 parts, citric acid 4 parts, Oleum menthae 5 parts, cane sugar powder 8 parts, ethanol 20 parts, 50 parts, water;
Prevent a preparation method for the buccal tablet of altitude sickness, its special character is to comprise the following steps:
(1) Radix Rhodiolae, Herba Saussureae Involueratae, Fructus Lycii are decocted with water secondary, 2 hours for the first time, second time 1.5 hours, merge and decoct liquid twice and filter formation filtrate;
(2) step (1) filtrate is added ethanol to alcohol content 60-65%, leave standstill 24 hours, filter, decompression filtrate recycling ethanol, and be condensed into thick paste;
(3) Stigma Croci, Lignum Santali Albi, Lignum Dalbergiae Odoriferae, Flos Caryophylli, Fructus Phyllanthi, Fructus Fragariae Ananssae, high mountain Radix Codonopsis, Radix Glycyrrhizae, Calculus Bovis, Moschus, Medulla Tetrapanacis, Radix Sophorae Tonkinensis, Rhizoma Belamcandae, Bulbus Fritillariae Thunbergii, Indigo Naturalis Poria, the Fructus Kochiae, Fructus Crataegi are decocted with water 2 hours, filter and form filtrate;
(4) step (3) filtrate is added ethanol to alcohol content 55-65%, leave standstill 24 hours, filter, decompression filtrate recycling ethanol, and be condensed into thick paste;
(5) step (2) thick paste is mixed with step (4) thick paste, add steviosin, citric acid, cane sugar powder, make granule;
(6) step (5) granule is mixed with Oleum menthae, tabletted.
Radix Rhodiolae: benefiting QI for activating blood circulation, promotes blood circulation and relievings asthma;
Herba Saussureae Involueratae: promoting blood circulation to restore menstrual flow, dispelling cold and removing dampness, strong muscle is supporing yang;
Fructus Lycii: sweet, flat, nourishing kidney, lung moistening;
Stigma Croci: invigorate blood circulation, blood stasis dispelling, tissue regeneration promoting, analgesia, stomach invigorating;
Lignum Santali Albi: acrid in the mouth, warm in nature, control trusted subordinate's pain, dysphagic vomiting, chest and diaphragm does not relax;
Lignum Dalbergiae Odoriferae: promoting flow of QI and blood, pain relieving, hemostasis;
Flos Caryophylli: sweet, pungent, hot greatly, warming the stomach, the kidney warming;
Fructus Phyllanthi: sweet, micro-puckery, cool.Relieving sore-throat by clearing away heat, nourishing the lung to arrest cough;
Fructus Fragariae Ananssae: nature and flavor are sweet, cool, the lung moistening and production of body fluid promoting, invigorating the spleen and regulating the stomach, inducing diuresis to remove edema, driving away summer heat;
High mountain Radix Codonopsis: Gan Ping, kind strengthening the spleen gas;
Radix Glycyrrhizae: sweet in the mouth, flat, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough;
Calculus Bovis: clear away heart-fire, eliminating phlegm, has one's ideas straightened out, cool liver, endogenous wind stopping, removing toxic substances;
Moschus: refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow;
Medulla Tetrapanacis: sweet in the mouth; Light; Cold nature, wet clearly diuretic;
Radix Sophorae Tonkinensis: relieve inflammation or internal heat, removing toxic substances, detumescence, pain relieving;
Rhizoma Belamcandae: for accumulation and obstruction of sputum, cough and asthma;
Bulbus Fritillariae Thunbergii: removing heat-phlegm, powder detoxifcation;
Indigo Naturalis: heat clearing away, blood cooling and ecchymoses removing, removing toxic substances, purging liver-fire, arresting convulsion;
Poria: promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming;
The Fructus Kochiae: clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.
A kind of buccal tablet preventing altitude sickness of the present invention, complement each other between each component, compatibility is reasonable, bring out the best in each other, altitude sickness symptom can be eliminated fast, the feature have evident in efficacy, instant effect, not easily recurring, especially to symptom Be very effective such as headache, nervous, tachypnea, loss of appetite, asthenia, weak, dizzy, Nausea and vomiting.
Detailed description of the invention
Below provide the specific embodiment of the present invention, be used for being described in further detail formation of the present invention.
Embodiment 1
The Chinese medicine of the present embodiment treatment asthma, is made up of following raw material by weight ratio: Radix Rhodiolae 10 parts, Herba Saussureae Involueratae 8 parts, Fructus Lycii 3 parts, Stigma Croci 6 parts, 3 parts, Lignum Santali Albi, Lignum Dalbergiae Odoriferae 2 parts, Flos Caryophylli 2 parts, Fructus Phyllanthi 3 parts, Fructus Fragariae Ananssae 2 parts, high mountain Radix Codonopsis 5 parts, 2 parts, Radix Glycyrrhizae, Calculus Bovis 3 parts, 4 parts, Moschus, Medulla Tetrapanacis 4 parts, Radix Sophorae Tonkinensis 3 parts, Rhizoma Belamcandae 4 parts, Bulbus Fritillariae Thunbergii 4 parts, Indigo Naturalis 2 parts, 2 parts, Poria, the Fructus Kochiae 2 parts, Fructus Crataegi 5 parts, steviosin 3 parts, citric acid 3 parts, Oleum menthae 4 parts, cane sugar powder 8 parts, ethanol 20 parts, 30 parts, water.
Embodiment 2
A kind of buccal tablet preventing altitude sickness of the present embodiment, is made up of following raw material by weight ratio: Radix Rhodiolae 20 parts, Herba Saussureae Involueratae 15 parts, Fructus Lycii 8 parts, Stigma Croci 10 parts, 7 parts, Lignum Santali Albi, Lignum Dalbergiae Odoriferae 6 parts, Flos Caryophylli 6 parts, Fructus Phyllanthi 7 parts, Fructus Fragariae Ananssae 9 parts, high mountain Radix Codonopsis 11 parts, 7 parts, Radix Glycyrrhizae, Calculus Bovis 5 parts, 8 parts, Moschus, Medulla Tetrapanacis 8 parts, Radix Sophorae Tonkinensis 7 parts, Rhizoma Belamcandae 8 parts, Bulbus Fritillariae Thunbergii 8 parts, Indigo Naturalis 6 parts, 6 parts, Poria, the Fructus Kochiae 6 parts, Fructus Crataegi 12 parts, steviosin 8 parts, citric acid 8 parts, Oleum menthae 9 parts, cane sugar powder 18 parts, ethanol 30 parts, 50 parts, water.
Embodiment 3
A kind of buccal tablet preventing altitude sickness of the present embodiment, is made up of the raw material of following optimal proportion by weight: Radix Rhodiolae 12 parts, Herba Saussureae Involueratae 12 parts, Fructus Lycii 5 parts, Stigma Croci 7 parts, 4 parts, Lignum Santali Albi, Lignum Dalbergiae Odoriferae 2 parts, Flos Caryophylli 2 parts, Fructus Phyllanthi 4 parts, Fructus Fragariae Ananssae 5 parts, high mountain Radix Codonopsis 8 parts, 3 parts, Radix Glycyrrhizae, Calculus Bovis 4 parts, 6 parts, Moschus, Medulla Tetrapanacis 6 parts, Radix Sophorae Tonkinensis 6 parts, Rhizoma Belamcandae 6 parts, Bulbus Fritillariae Thunbergii 6 parts, Indigo Naturalis 5 parts, 5 parts, Poria, the Fructus Kochiae 5 parts, Fructus Crataegi 8 parts, steviosin 4 parts, citric acid 4 parts, Oleum menthae 5 parts, cane sugar powder 8 parts, ethanol 20 parts, 50 parts, water.
The preparation method of the buccal tablet of above embodiment prevention altitude sickness, comprises the following steps:
(1) Radix Rhodiolae, Herba Saussureae Involueratae, Fructus Lycii are decocted with water secondary, 2 hours for the first time, second time 1.5 hours, merge and decoct liquid twice and filter formation filtrate;
(2) step (1) filtrate is added ethanol to alcohol content 65%, leave standstill 24 hours, filter, decompression filtrate recycling ethanol, and be condensed into thick paste;
(3) Stigma Croci, Lignum Santali Albi, Lignum Dalbergiae Odoriferae, Flos Caryophylli, Fructus Phyllanthi, Fructus Fragariae Ananssae, high mountain Radix Codonopsis, Radix Glycyrrhizae, Calculus Bovis, Moschus, Medulla Tetrapanacis, Radix Sophorae Tonkinensis, Rhizoma Belamcandae, Bulbus Fritillariae Thunbergii, Indigo Naturalis Poria, the Fructus Kochiae, Fructus Crataegi are decocted with water 2 hours, filter and form filtrate;
(4) step (3) filtrate is added ethanol to alcohol content 65%, leave standstill 24 hours, filter.Decompression filtrate recycling ethanol, and be condensed into thick paste;
(5) step (2) thick paste is mixed with step (4) thick paste, add steviosin, citric acid, cane sugar powder, make granule;
(6) step (5) granule is mixed with Oleum menthae, tabletted.
Clinical trial: by patient according to extent, common symptom has the criterions of therapeutical effect such as headache, nervous, tachypnea, loss of appetite, asthenia, weak, dizzy, Nausea and vomiting:
Effective: all transference cures;
Take a turn for the better: most of symptom makes moderate progress;
Invalid: without any effect after treatment;
It is below therapeutic effect
Extent Case load Effective number of cases Improvement number of cases Invalid number of cases Total effective rate
Mild reaction 80 70 8 2 97.5%
Moderate is reacted 80 65 10 5 93.75%
Severe reaction 80 61 13 6 92.5%

Claims (3)

1. one kind is prevented the buccal tablet of altitude sickness, it is characterized in that being made up of following raw material by weight ratio: Radix Rhodiolae 10-20 part, Herba Saussureae Involueratae 8-15 part, Fructus Lycii 3-8 part, Stigma Croci 6-10 part, Lignum Santali Albi 3-7 part, Lignum Dalbergiae Odoriferae 2-6 part, Flos Caryophylli 2-6 part, Fructus Phyllanthi 3-7 part, Fructus Fragariae Ananssae 2-9 part, high mountain Radix Codonopsis 5-11 part, Radix Glycyrrhizae 2-7 part, Calculus Bovis 3-5 part, Moschus 4-8 part, Medulla Tetrapanacis 4-8 part, Radix Sophorae Tonkinensis 3-7 part, Rhizoma Belamcandae 4-8 part, Bulbus Fritillariae Thunbergii 4-8 part, Indigo Naturalis 2-6 part, Poria 2-6 part, Fructus Kochiae 2-6 part, Fructus Crataegi 5-12 part, steviosin 3-8 part, citric acid 3-8 part, Oleum menthae 4-9 part, cane sugar powder 8-18 part, ethanol 20-30 part, water 30-50 part.
2. a kind of buccal tablet preventing altitude sickness according to claim 1, it is characterized in that being made up of the raw material of following optimal proportion by weight: Radix Rhodiolae 12 parts, Herba Saussureae Involueratae 12 parts, Fructus Lycii 5 parts, Stigma Croci 7 parts, 4 parts, Lignum Santali Albi, Lignum Dalbergiae Odoriferae 2 parts, Flos Caryophylli 2 parts, Fructus Phyllanthi 4 parts, Fructus Fragariae Ananssae 5 parts, high mountain Radix Codonopsis 8 parts, 3 parts, Radix Glycyrrhizae, Calculus Bovis 4 parts, 6 parts, Moschus, Medulla Tetrapanacis 6 parts, Radix Sophorae Tonkinensis 6 parts, Rhizoma Belamcandae 6 parts, Bulbus Fritillariae Thunbergii 6 parts, Indigo Naturalis 5 parts, 5 parts, Poria, the Fructus Kochiae 5 parts, Fructus Crataegi 8 parts, steviosin 4 parts, citric acid 4 parts, Oleum menthae 5 parts, cane sugar powder 8 parts, ethanol 20 parts, 50 parts, water.
3. a kind of preparation method of preventing the buccal tablet of altitude sickness described in claim 1 or 2, is characterized in that comprising the following steps:
(1) Radix Rhodiolae, Herba Saussureae Involueratae, Fructus Lycii are decocted with water secondary, 2 hours for the first time, second time 1.5 hours, merge and decoct liquid twice and filter formation filtrate;
(2) step (1) filtrate is added ethanol to alcohol content 60-65%, leave standstill 24 hours, filter, decompression filtrate recycling ethanol, and be condensed into thick paste;
(3) Stigma Croci, Lignum Santali Albi, Lignum Dalbergiae Odoriferae, Flos Caryophylli, Fructus Phyllanthi, Fructus Fragariae Ananssae, high mountain Radix Codonopsis, Radix Glycyrrhizae, Calculus Bovis, Moschus, Medulla Tetrapanacis, Radix Sophorae Tonkinensis, Rhizoma Belamcandae, Bulbus Fritillariae Thunbergii, Indigo Naturalis Poria, the Fructus Kochiae, Fructus Crataegi are decocted with water 2 hours, filter and form filtrate;
(4) step (3) filtrate is added ethanol to alcohol content 55-65%, leave standstill 24 hours, filter, decompression filtrate recycling ethanol, and be condensed into thick paste;
(5) step (2) thick paste is mixed with step (4) thick paste, add steviosin, citric acid, cane sugar powder, make granule;
(6) step (5) granule is mixed with Oleum menthae, tabletted.
CN201410590331.5A 2014-10-29 2014-10-29 Buccal tablets for preventing altitude stress and preparation method thereof Pending CN104288476A (en)

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Publication number Priority date Publication date Assignee Title
CN104667205A (en) * 2015-03-31 2015-06-03 张丽 Oral liquid for preventing altitude stress
WO2020062913A1 (en) 2018-09-25 2020-04-02 中国人民解放军总医院 Medical use of prostacyclin receptor agonist
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