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BR9811971A - Processo para a preparação de glufosinato e de produtos intermediários para ele - Google Patents

Processo para a preparação de glufosinato e de produtos intermediários para ele

Info

Publication number
BR9811971A
BR9811971A BR9811971-0A BR9811971A BR9811971A BR 9811971 A BR9811971 A BR 9811971A BR 9811971 A BR9811971 A BR 9811971A BR 9811971 A BR9811971 A BR 9811971A
Authority
BR
Brazil
Prior art keywords
glufosinate
preparation
intermediate products
compounds
sym
Prior art date
Application number
BR9811971-0A
Other languages
English (en)
Other versions
BR9811971B1 (pt
Inventor
Lothar Willms
Original Assignee
Hoechst Schering Agrevo Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Schering Agrevo Gmbh filed Critical Hoechst Schering Agrevo Gmbh
Publication of BR9811971A publication Critical patent/BR9811971A/pt
Publication of BR9811971B1 publication Critical patent/BR9811971B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/12—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing acyclic or cycloaliphatic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657172—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and one oxygen atom being part of a (thio)phosphinic acid ester: (X = O, S)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32—Esters thereof
    • C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3211—Esters of acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO PARA A PREPARAçãO DE GLUFOSINATO E DE PRODUTOS INTERMEDIáRIOS PARA ELE''<D>. Glufosinato e o análogo de 2-metila do mesmo podem ser preparados em uma síntese de mais do que uma etapa a partir de compostos de metil-fósforo (II) com ceto-compostos (III) insaturados, por meio de adutos (IV), reação subseq³ente sob condições de uma Síntese de Strecke e hidrólise subseq³ente da aminonitrila (V): Etapa 1: (II) + (III) <sym> aduto IV; Etapa 2: aduto IV por exemplo NH~ 3~/NaCN/NH~ 4~CI <sym> (V); Etapa 3: hidrólise de (V) para formar glufosinato. Como adutos (IV) podem ser identificados diferentes compostos, em conformidade com as condições de processo e com os substratos.
BRPI9811971-0A 1997-08-20 1998-08-08 processo para a preparação de glufosinato, bem como composto intermediário e seu processo de preparação. BR9811971B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19736125A DE19736125A1 (de) 1997-08-20 1997-08-20 Verfahren zur Herstellung von Glufosinate und phosphorhaltige alpha-Aminonitrile als Zwischenprodukte
DE19736125.0 1997-08-20
PCT/EP1998/005053 WO1999009039A1 (de) 1997-08-20 1998-08-08 Verfahren zur herstellung von glufosinate und zwischenprodukte dafür

Publications (2)

Publication Number Publication Date
BR9811971A true BR9811971A (pt) 2000-08-15
BR9811971B1 BR9811971B1 (pt) 2010-12-28

Family

ID=7839559

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9811971-0A BR9811971B1 (pt) 1997-08-20 1998-08-08 processo para a preparação de glufosinato, bem como composto intermediário e seu processo de preparação.

Country Status (27)

Country Link
US (1) US6359162B1 (pt)
EP (1) EP1005475B1 (pt)
JP (1) JP4519316B2 (pt)
KR (1) KR100674326B1 (pt)
CN (1) CN1261442C (pt)
AR (1) AR015932A1 (pt)
AT (1) ATE258180T1 (pt)
AU (1) AU756471B2 (pt)
BR (1) BR9811971B1 (pt)
CA (1) CA2301181C (pt)
CO (1) CO5031316A1 (pt)
CZ (1) CZ2000593A3 (pt)
DE (2) DE19736125A1 (pt)
DK (1) DK1005475T3 (pt)
ES (1) ES2214727T3 (pt)
HU (1) HUP0003501A3 (pt)
IL (1) IL134633A0 (pt)
MY (1) MY132853A (pt)
PH (1) PH11998002119A1 (pt)
PL (1) PL191587B1 (pt)
PT (1) PT1005475E (pt)
RU (1) RU2275376C2 (pt)
TR (1) TR200000456T2 (pt)
TW (1) TW530063B (pt)
UA (1) UA66806C2 (pt)
WO (1) WO1999009039A1 (pt)
ZA (1) ZA987465B (pt)

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EP2065391B1 (en) * 2006-09-20 2014-06-18 Meiji Seika Pharma Co., Ltd. Method for producing phosphorus-containing a-amino acid and production intermediate thereof
US8981142B2 (en) 2010-04-14 2015-03-17 Strategic Enzyme Applications, Inc. Process of producing phosphinothricin employing nitrilases
CN102372738B (zh) * 2010-08-14 2017-11-10 武汉工程大学 Lj反应在制备维蒂希试剂和草铵膦中的应用
TWI546311B (zh) 2011-09-30 2016-08-21 明治製菓藥業股份有限公司 固殺草ｐ游離酸之製造方法
CN102372739B (zh) * 2011-12-05 2017-06-16 河北威远生化农药有限公司 一种草铵膦的合成方法
CN102399239A (zh) * 2011-12-27 2012-04-04 江苏优士化学有限公司 一种草铵膦及类似物的合成方法
CN102399240A (zh) * 2011-12-27 2012-04-04 江苏优士化学有限公司 一种改进的草铵膦及类似物的合成方法
CN103183707B (zh) * 2011-12-30 2016-06-15 中化蓝天集团有限公司 一种草胺膦的制备方法
CN102584893B (zh) * 2012-02-07 2015-03-04 浙江工业大学 一种草铵膦的制备方法
CN103374030B (zh) * 2012-04-13 2016-03-23 浙江新安化工集团股份有限公司 一种制备草铵膦的方法及其中间体的制备方法
CN103483379A (zh) * 2013-09-26 2014-01-01 江苏辉丰农化股份有限公司 一种草铵膦酸的制备方法
AU2015261096B9 (en) 2014-05-13 2019-10-10 Basf Se Process for preparing phosphorus-containing cyanohydrins
CN104558033B (zh) * 2014-12-19 2016-05-18 浙江工业大学 一种l-草铵膦-n-羧酸酐及其制备和应用
BR112017023253B1 (pt) 2015-04-27 2022-09-13 Basf Se Combinações de herbicida que compreendem glufosinato e indaziflam
CN108026122B (zh) 2015-09-02 2021-03-09 拜耳作物科学股份公司 制备含磷氰醇酯的方法
JP2018529663A (ja) 2015-09-02 2018-10-11 バイエル・クロップサイエンス・アクチェンゲゼルシャフト リンを含んでいるシアノヒドリンエステルを製造する方法
KR20180048662A (ko) 2015-09-02 2018-05-10 바이엘 크롭사이언스 악티엔게젤샤프트 인 함유 시아노히드린 에스테르의 제조 방법
BR112018004247A2 (pt) 2015-09-02 2018-09-25 Bayer Cropscience Aktiengesellschaft método para produção de ésteres de cianidrina contendo fósforo.
JP6826110B2 (ja) 2015-09-29 2021-02-03 ビーエイエスエフ・ソシエタス・エウロパエアＢａｓｆ Ｓｅ ホスフィネート類を製造する方法
CN107236001A (zh) * 2016-04-06 2017-10-10 四川省乐山市福华通达农药科技有限公司 一种膦醛的合成方法
CN107417721B (zh) * 2016-05-24 2019-05-28 四川福思达生物技术开发有限责任公司 一种氢氰酸加成工艺
WO2018108797A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von l-glufosinat oder dessen salzen unter verwendung von ephedrin
WO2018108794A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von d-glufosinat oder dessen salzen unter verwendung von ephedrin
EP3392237B1 (de) 2017-04-21 2019-10-02 Evonik Degussa GmbH Verfahren zur herstellung von acroleincyanhydrinen
BR112020001209B1 (pt) 2017-07-21 2023-04-11 Basf Se Processos para preparar uma mistura e para preparar glufosinato e uso de uma mistura
WO2019121362A1 (de) 2017-12-19 2019-06-27 Basf Se VERFAHREN ZUR HERSTELLUNG VON PHOSPHORHALTIGEN α-AMINONITRILEN
CN109134534B (zh) * 2018-08-08 2020-09-08 江苏好收成韦恩农化股份有限公司 一种3,3-二烷氧基丙基甲基膦酸酯简易制备方法
KR102131687B1 (ko) * 2018-09-10 2020-07-08 주식회사 휴런 파킨슨 병 진단 장치 및 방법
BR112021013261B1 (pt) 2019-01-11 2024-02-20 Cj Cheiljedang Corporation Método para produzir l-glufosinato
CN111662324B (zh) * 2019-03-05 2023-02-24 利尔化学股份有限公司 一种制备l-草铵膦的方法
CN111662325B (zh) * 2019-03-05 2023-03-24 利尔化学股份有限公司 一种制备l-草铵膦的方法
CN111662326B (zh) * 2019-03-05 2023-03-24 利尔化学股份有限公司 一种制备l-草铵膦的方法
CN110003269B (zh) * 2019-04-29 2022-04-05 利尔化学股份有限公司 低能耗生产草铵膦的方法
CN110590836B (zh) * 2019-09-30 2022-07-26 江苏七洲绿色化工股份有限公司 一种草铵膦中间体的合成方法
CN112898338A (zh) * 2019-12-04 2021-06-04 利尔化学股份有限公司 草铵膦中间体及草铵膦的制备方法
CN111659330B (zh) * 2020-04-23 2021-05-07 河北威远生物化工有限公司 一种连续化生产草铵膦的工艺与设备
CN112358499A (zh) * 2020-11-12 2021-02-12 江苏春江润田农化有限公司 一种草铵膦的合成方法
CA3198877A1 (en) * 2021-07-20 2023-01-26 Min Xu Method for preparing glufosinate or analogues thereof
EP4151643A1 (en) 2021-09-16 2023-03-22 Evonik Operations GmbH Improved process for production of phosphoesters of glufosinate precursors
CN114163472B (zh) * 2021-11-27 2024-08-09 永农生物科学有限公司 醇溶剂下合成α-氨基腈的方法及草铵膦的合成方法
CN116041387B (zh) * 2022-11-17 2023-07-14 永农生物科学有限公司 一种草铵膦的制备方法
WO2024175643A1 (en) 2023-02-23 2024-08-29 Basf Se A process for preparing l-glufosinate from cyanhydrine or cyanhydrine derivatives

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JPS5484529A (en) * 1977-12-19 1979-07-05 Meiji Seika Kaisha Ltd Production of d,l-2-amino-4-methylphosphinobutyric acid
DE2849003A1 (de) * 1978-11-11 1980-08-21 Hoechst Ag Phosphorhaltige cyanhydrinderivate und verfahren zu ihrer herstellung
DE3508573A1 (de) 1985-03-11 1986-09-11 Hoechst Ag, 6230 Frankfurt Phosphorhaltige (alpha)-aminonitrile und verfahren zu ihrer herstellung
JP2615777B2 (ja) 1987-05-26 1997-06-04 日産化学工業株式会社 ホスフィニルアミノ酸誘導体の製造方法

Also Published As

Publication number Publication date
AR015932A1 (es) 2001-05-30
CA2301181A1 (en) 1999-02-25
CN1267305A (zh) 2000-09-20
UA66806C2 (uk) 2004-06-15
MY132853A (en) 2007-10-31
TW530063B (en) 2003-05-01
DE59810636D1 (de) 2004-02-26
CN1261442C (zh) 2006-06-28
PL338855A1 (en) 2000-11-20
DK1005475T3 (da) 2004-05-17
PH11998002119A1 (en) 2003-10-10
AU9259898A (en) 1999-03-08
CO5031316A1 (es) 2001-04-27
WO1999009039A1 (de) 1999-02-25
TR200000456T2 (tr) 2000-07-21
EP1005475A1 (de) 2000-06-07
CA2301181C (en) 2008-08-05
ES2214727T3 (es) 2004-09-16
KR20010023069A (ko) 2001-03-26
HUP0003501A2 (en) 2001-03-28
US6359162B1 (en) 2002-03-19
PT1005475E (pt) 2004-06-30
AU756471B2 (en) 2003-01-16
RU2275376C2 (ru) 2006-04-27
DE19736125A1 (de) 1999-02-25
JP4519316B2 (ja) 2010-08-04
CZ2000593A3 (cs) 2000-06-14
ATE258180T1 (de) 2004-02-15
PL191587B1 (pl) 2006-06-30
EP1005475B1 (de) 2004-01-21
BR9811971B1 (pt) 2010-12-28
ZA987465B (en) 1999-02-22
KR100674326B1 (ko) 2007-01-24
HUP0003501A3 (en) 2002-01-28
IL134633A0 (en) 2001-04-30
JP2001515084A (ja) 2001-09-18

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