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BR112021015719A2 - Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses - Google Patents

Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses

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Publication number
BR112021015719A2
BR112021015719A2 BR112021015719A BR112021015719A BR112021015719A2 BR 112021015719 A2 BR112021015719 A2 BR 112021015719A2 BR 112021015719 A BR112021015719 A BR 112021015719A BR 112021015719 A BR112021015719 A BR 112021015719A BR 112021015719 A2 BR112021015719 A2 BR 112021015719A2
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BR
Brazil
Prior art keywords
xylitol
meg
products
microorganisms
optionally
Prior art date
Application number
BR112021015719A
Other languages
English (en)
Inventor
Johannes Koch Daniel
Felipe Galzerani
Pederson Parizzi Lucas
Original Assignee
Braskem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braskem Sa filed Critical Braskem Sa
Publication of BR112021015719A2 publication Critical patent/BR112021015719A2/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
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    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
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    • C12P7/00—Preparation of oxygen-containing organic compounds
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
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    • C12P7/00—Preparation of oxygen-containing organic compounds
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01043—Phosphogluconate 2-dehydrogenase (1.1.1.43)
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    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
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    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008—Phosphate acetyltransferase (2.3.1.8)
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    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01011—6-Phosphofructokinase (2.7.1.11)
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    • C12Y207/02003—Phosphoglycerate kinase (2.7.2.3)
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    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
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    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
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    • C12Y504/02—Phosphotransferases (phosphomutases) (5.4.2)

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

microorganismos e métodos para produção de compostosoxigenados a partir de hexoses. a invenção refere-se a micro-organismos recombinantes úteis na biossíntese de monoetileno glicol (meg), ou opcionalmente meg e um coproduto ou mais coprodutos, a partir de uma matéria-prima ou mais matérias-primas de hexose. a presente invenção refere-se também a micro-organismos recombinantes úteis na biossíntese de ácido glicólico (ga) ou, opcionalmente, ga e um coproduto ou mais coprodutos, a partir de uma matéria-prima ou mais matérias-primas de hexose. a presente invenção refere-se a micro-organismos recombinantes úteis na biossíntese de xilitol, ou opcionalmente xilitol e um coproduto ou mais coprodutos, a partir de uma matéria-prima ou mais matérias-primas de hexose. são também providos métodos de produção de meg (ou ga ou xilitol), ou opcionalmente meg (ou ga ou xilitol) e um coproduto ou mais coprodutos, a partir de uma matéria-prima ou mais matérias-primas de hexose usando os micro-organismos recombinantes, bem como composições compreendendo os micro-organismos recombinantes e/ou os produtos meg (ou ga ou xilitol) ou, opcionalmente, meg (ou ga ou xilitol) e um coproduto ou mais coprodutos.
BR112021015719A 2019-02-20 2020-02-20 Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses BR112021015719A2 (pt)

Applications Claiming Priority (2)

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US201962808247P 2019-02-20 2019-02-20
PCT/BR2020/050052 WO2020168407A1 (en) 2019-02-20 2020-02-20 Microorganisms and methods for the production of oxygenated compounds from hexoses

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US (2) US12006526B2 (pt)
EP (1) EP3908663A1 (pt)
JP (1) JP7504112B2 (pt)
CN (1) CN113710807A (pt)
BR (1) BR112021015719A2 (pt)
WO (1) WO2020168407A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102233375B1 (ko) * 2018-12-11 2021-03-31 씨제이제일제당 주식회사 신규 싸이코스-6-인산의 탈인산화 효소, 이를 포함하는 싸이코스 생산용 조성물, 및 이를 이용한 싸이코스 제조방법
CN111593014B (zh) * 2020-06-24 2022-07-05 江南大学 联产1,3-丙二醇和d-1,2,4-丁三醇的方法
CN112210551A (zh) * 2020-10-15 2021-01-12 天津科技大学 一种d-阿洛酮糖-3-差向异构酶固定化酶制备方法
WO2022164752A1 (en) * 2021-01-28 2022-08-04 Pioneer Hi-Bred International, Inc. Clubroot resistance in brassica
CN113447585B (zh) * 2021-06-28 2022-03-15 中国食品药品检定研究院 基于液相色谱评价体外辅助生殖用液质量的方法
WO2023220546A1 (en) * 2022-05-09 2023-11-16 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of arabitol
CN118685438A (zh) * 2024-08-09 2024-09-24 微元合成生物技术(北京)有限公司 一种基于nad(h)辅因子循环系统合成d-木糖醇的方法及其专用工程菌

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW313589B (pt) 1991-12-12 1997-08-21 Wacker Chemie Gmbh
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
JP4066543B2 (ja) 1998-01-12 2008-03-26 味の素株式会社 発酵法によるｌ−セリンの製造法
WO2005113759A2 (en) 2004-05-19 2005-12-01 Biotechnology Research And Development Corporation Microbial production of xylitol via a hexose phosphate and a pentose phosphate intermediate
WO2007140816A1 (en) * 2006-06-09 2007-12-13 Metabolic Explorer Glycolic acid production by fermentation from renewable resources
WO2007144018A1 (en) 2006-06-12 2007-12-21 Metabolic Explorer Ethanolamine production by fermentation
DE102006027683A1 (de) 2006-06-14 2007-12-20 Siemens Ag Verfahren und Vorrichtung zur Vernetzung einer automatisierten Anlage
KR20110117131A (ko) 2008-12-31 2011-10-26 메타볼릭 익스플로러 디올의 제조 방법
EP2233562A1 (en) 2009-03-24 2010-09-29 Metabolic Explorer Method for producing high amount of glycolic acid by fermentation
EP2459711B1 (en) 2009-07-30 2016-04-06 Metabolic Explorer Mutant YqhD enzyme for the production of a biochemical by fermentation
WO2011130378A1 (en) 2010-04-13 2011-10-20 Genomatica, Inc. Microorganisms and methods for the production of ethylene glycol
CA2813868A1 (en) 2010-10-19 2012-04-26 Global Bioenergies Production of alkenes by combined enzymatic conversion of 3-hydroxyalkanoic acids
SG11201401249PA (en) * 2011-10-07 2014-05-29 Danisco Us Inc Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene
KR101351879B1 (ko) 2012-02-06 2014-01-22 명지대학교 산학협력단 에탄―１，２―디올 생산 미생물 및 이를 이용한 에탄―１，２―디올 생산 방법
US20130316416A1 (en) 2012-02-23 2013-11-28 Massachusetts Institute Of Technology Engineering microbes and metabolic pathways for the production of ethylene glycol
WO2014049382A2 (en) 2012-09-26 2014-04-03 Metabolic Explorer Ethylenediamine fermentative production by a recombinant microorganism
CN104178443B (zh) 2013-05-24 2017-04-12 中国科学院天津工业生物技术研究所 生产丁二酸的重组大肠杆菌及其应用
EP3019604B1 (en) 2013-07-09 2020-08-26 Global Bioenergies Mevalonate diphosphate decarboxylase variants
WO2015042588A1 (en) 2013-09-23 2015-03-26 Braskem S.A. Engineered enzyme having acetoacetyl-coa hydrolase activity, microorganisms comprising same, and methods of using same
FR3028529B1 (fr) * 2014-11-19 2016-12-30 Inst Nat De La Rech Agronomique Inra Procede de production d'au moins un metabolite d'interet par transformation d'un pentose dans un microorganisme
AU2017231728B2 (en) 2016-03-09 2021-12-16 Braskem S.A. Microorganisms and methods for the co-production of ethylene glycol and three carbon compounds
US20200048662A1 (en) * 2016-10-11 2020-02-13 Braskem S.A. Microorganisms and methods for the co-production of ethylene glycol and isobutene
EP3354742A1 (en) * 2017-01-26 2018-08-01 Metabolic Explorer Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid

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JP7504112B2 (ja) 2024-06-21
JP2022521904A (ja) 2022-04-13
US20200283806A1 (en) 2020-09-10
WO2020168407A1 (en) 2020-08-27
US12006526B2 (en) 2024-06-11
US20240392329A1 (en) 2024-11-28
CN113710807A (zh) 2021-11-26
EP3908663A1 (en) 2021-11-17

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