BR112015022197A8 - uso de um composto para fabricação de um medicamento ou composição farmacêutica para o tratamento de cataplexia - Google Patents
uso de um composto para fabricação de um medicamento ou composição farmacêutica para o tratamento de cataplexia Download PDFInfo
- Publication number
- BR112015022197A8 BR112015022197A8 BR112015022197A BR112015022197A BR112015022197A8 BR 112015022197 A8 BR112015022197 A8 BR 112015022197A8 BR 112015022197 A BR112015022197 A BR 112015022197A BR 112015022197 A BR112015022197 A BR 112015022197A BR 112015022197 A8 BR112015022197 A8 BR 112015022197A8
- Authority
- BR
- Brazil
- Prior art keywords
- cataplexy
- medicament
- manufacture
- compound
- pharmaceutical composition
- Prior art date
Links
- 208000001573 Cataplexy Diseases 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
- A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/02—Carbamic acids; Salts of carbamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
treatment of cataplexy abstract the present invention relates to a method of treating cataplexy in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds. _____________________________________________________ resumo patente de invenção: "tratamento de cataplexia". a presente invenção se refere a um método para o tratamento de cataplexia em um indivíduo com necessidade do mesmo, compreendendo administrar ao indivíduo a uma quantidade terapeuticamente eficaz de determinados compostos carbamato.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361778998P | 2013-03-13 | 2013-03-13 | |
US61/778,998 | 2013-03-13 | ||
PCT/US2014/023969 WO2014164969A1 (en) | 2013-03-13 | 2014-03-12 | Treatment of cataplexy |
Publications (3)
Publication Number | Publication Date |
---|---|
BR112015022197A2 BR112015022197A2 (pt) | 2017-07-18 |
BR112015022197A8 true BR112015022197A8 (pt) | 2019-11-26 |
BR112015022197B1 BR112015022197B1 (pt) | 2022-06-07 |
Family
ID=51530017
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015022197-1A BR112015022197B1 (pt) | 2013-03-13 | 2014-03-12 | Uso de um composto para o tratamento de cataplexia |
Country Status (22)
Country | Link |
---|---|
US (6) | US9359290B2 (pt) |
EP (1) | EP2968208B1 (pt) |
JP (2) | JP6530741B2 (pt) |
KR (1) | KR102192554B1 (pt) |
CN (1) | CN105431142B (pt) |
AU (1) | AU2014248849B2 (pt) |
BR (1) | BR112015022197B1 (pt) |
CA (1) | CA2905457A1 (pt) |
DK (1) | DK2968208T3 (pt) |
ES (1) | ES2927675T3 (pt) |
HK (1) | HK1219236A1 (pt) |
HR (1) | HRP20221018T1 (pt) |
HU (1) | HUE060060T2 (pt) |
MX (1) | MX2015012644A (pt) |
MY (1) | MY177740A (pt) |
PH (1) | PH12015502075A1 (pt) |
PT (1) | PT2968208T (pt) |
RU (2) | RU2019114940A (pt) |
SG (1) | SG11201507121RA (pt) |
SI (1) | SI2968208T1 (pt) |
TW (2) | TWI663971B (pt) |
WO (1) | WO2014164969A1 (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101217949B (zh) * | 2005-06-08 | 2012-10-17 | 爱思开生物制药株式会社 | 治疗睡眠-清醒病症 |
US8741950B2 (en) | 2009-06-22 | 2014-06-03 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating or preventing fatigue |
EP2968208B1 (en) * | 2013-03-13 | 2022-07-20 | Jazz Pharmaceuticals Ireland Limited | Treatment of cataplexy |
WO2015010014A1 (en) | 2013-07-18 | 2015-01-22 | Jazz Pharmaceuticals International Iii Limited | Treatment for obesity |
US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US10195151B2 (en) * | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
MY197630A (en) | 2016-09-06 | 2023-06-29 | Sk Biopharmaceuticals Co Ltd | Solvate form of (r)-2-amino-3-phenylpropyl carbamate |
SG11201903076QA (en) | 2016-10-06 | 2019-05-30 | Jazz Pharmaceuticals International Iii Ltd | Carbamoyl phenylalaninol compounds and uses therof |
JP2020528075A (ja) | 2017-06-02 | 2020-09-17 | ジャズ ファーマシューティカルズ アイルランド リミテッド | 過度の眠気を処置するための方法および組成物 |
US11413264B2 (en) | 2017-07-31 | 2022-08-16 | Jazz Pharmaceuticals Ireland Limited | Carbamoyl phenylalaninol analogs and uses thereof |
CN111328282A (zh) * | 2017-09-12 | 2020-06-23 | 奥维德医疗公司 | 加波沙朵在治疗发作性睡病中的用途 |
US20210106522A1 (en) | 2018-01-29 | 2021-04-15 | Cognos Therapeutics, Inc. | Intratumoral delivery of bortezomib |
US20190381056A1 (en) | 2018-06-17 | 2019-12-19 | Axsome Therapeutics, Inc. | Compositions for delivery of reboxetine |
WO2021113163A1 (en) * | 2019-12-03 | 2021-06-10 | Axsome Therapeutics, Inc. | Use of reboxetine to treat nervous system disorders |
US11020402B2 (en) | 2018-10-15 | 2021-06-01 | Axsome Therapeutics, Inc. | Use of reboxetine to treat narcolepsy |
WO2020081461A1 (en) * | 2018-10-15 | 2020-04-23 | Axsome Therapeutics, Inc. | Use of reboxetine to treat narcolepsy |
US20200147093A1 (en) | 2018-10-15 | 2020-05-14 | Axsome Therapeutics, Inc. | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
JP7553453B2 (ja) | 2019-03-01 | 2024-09-18 | フラメル アイルランド リミテッド | 食事摂取状態における改善された薬物動態を有するガンマ-ヒドロキシ酪酸塩組成物 |
CN114746097A (zh) * | 2019-12-03 | 2022-07-12 | 艾克萨姆治疗公司 | 瑞波西汀治疗神经系统障碍的用途 |
US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
KR102390194B1 (ko) | 2020-08-03 | 2022-04-25 | 셀라이온바이오메드 주식회사 | 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물 |
US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
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US178429A (en) * | 1876-06-06 | Improvement in hulling-machines | ||
JPS58156351A (ja) * | 1982-03-11 | 1983-09-17 | Sumitomo Chem Co Ltd | メタクリル酸合成触媒の再生方法 |
CZ285762B6 (cs) | 1993-06-10 | 1999-11-17 | Eli Lilly And Company | Farmaceutický prostředek vhodný pro prevenci dávení a zvracení a pro ošetřování sexuální dysfunkce savců a jeho použití |
KR100197892B1 (ko) | 1994-09-09 | 1999-06-15 | 남창우 | 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법 |
US5756817C1 (en) | 1995-02-11 | 2001-04-17 | Sk Corp | O-carbamoyl-phenylananinol compounds their pharmaceutically useful salts and process for preparing the same |
KR0173862B1 (ko) | 1995-02-11 | 1999-04-01 | 조규향 | O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
KR0173863B1 (ko) | 1995-04-10 | 1999-04-01 | 조규향 | 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
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US6204245B1 (en) * | 1999-09-17 | 2001-03-20 | The Regents Of The University Of California | Treatment of narcolepsy with immunosuppressants |
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GB0109103D0 (en) * | 2001-04-11 | 2001-05-30 | Pfizer Ltd | Novel compounds |
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CN1960981A (zh) * | 2004-03-31 | 2007-05-09 | 詹森药业有限公司 | 作为组胺h3受体调节剂的非咪唑杂环化合物 |
JP2008512386A (ja) * | 2004-09-07 | 2008-04-24 | オーファン メディカル,インコーポレイティド | 改良型ghb組成物 |
MX2007005172A (es) | 2004-10-28 | 2007-06-22 | Sk Corp | Terapia adjunta para la depresion. |
CN101217949B (zh) * | 2005-06-08 | 2012-10-17 | 爱思开生物制药株式会社 | 治疗睡眠-清醒病症 |
KR101335942B1 (ko) | 2005-06-22 | 2013-12-04 | 에스케이바이오팜 주식회사 | 성기능 장애의 치료 |
BRPI0520451A2 (pt) | 2005-07-26 | 2009-05-12 | Janssen Pharmaceutica Nv | métodos para tratamento de distúrbios associados a substáncias quìmicas |
FR2903904A1 (fr) * | 2006-07-21 | 2008-01-25 | Bioprojet Soc Civ Ile | Association de modafinil et d'un antagoniste ou agoniste inverse du recepteur h3 |
AU2007313017A1 (en) | 2006-10-13 | 2008-04-24 | Janssen Pharmaceutica, N.V. | Phenylalkylamino carbamate compositions |
JP2010510175A (ja) * | 2006-11-10 | 2010-04-02 | ディメリックス・バイオサイエンス・ピーティーワイ・リミテッド | 甲状腺刺激ホルモン放出ホルモン受容体−オレキシン受容体のヘテロダイマー/オリゴマー |
US8741950B2 (en) * | 2009-06-22 | 2014-06-03 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating or preventing fatigue |
US8232315B2 (en) | 2009-06-26 | 2012-07-31 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating drug addiction and improving addiction-related behavior |
CN102762201B (zh) | 2009-11-06 | 2013-12-18 | 爱思开生物制药株式会社 | 注意力缺陷/多动症的治疗方法 |
US8927602B2 (en) | 2009-11-06 | 2015-01-06 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating fibromyalgia syndrome |
US8623913B2 (en) | 2010-06-30 | 2014-01-07 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating restless legs syndrome |
US9610274B2 (en) | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
EP2968208B1 (en) * | 2013-03-13 | 2022-07-20 | Jazz Pharmaceuticals Ireland Limited | Treatment of cataplexy |
-
2014
- 2014-03-12 EP EP14778088.6A patent/EP2968208B1/en active Active
- 2014-03-12 TW TW103108612A patent/TWI663971B/zh active
- 2014-03-12 RU RU2019114940A patent/RU2019114940A/ru not_active Application Discontinuation
- 2014-03-12 DK DK14778088.6T patent/DK2968208T3/da active
- 2014-03-12 SG SG11201507121RA patent/SG11201507121RA/en unknown
- 2014-03-12 KR KR1020157027978A patent/KR102192554B1/ko active IP Right Grant
- 2014-03-12 WO PCT/US2014/023969 patent/WO2014164969A1/en active Application Filing
- 2014-03-12 MX MX2015012644A patent/MX2015012644A/es unknown
- 2014-03-12 HU HUE14778088A patent/HUE060060T2/hu unknown
- 2014-03-12 TW TW108107074A patent/TWI684450B/zh active
- 2014-03-12 CN CN201480027152.9A patent/CN105431142B/zh active Active
- 2014-03-12 AU AU2014248849A patent/AU2014248849B2/en active Active
- 2014-03-12 HR HRP20221018TT patent/HRP20221018T1/hr unknown
- 2014-03-12 US US14/205,423 patent/US9359290B2/en active Active
- 2014-03-12 CA CA2905457A patent/CA2905457A1/en not_active Abandoned
- 2014-03-12 PT PT147780886T patent/PT2968208T/pt unknown
- 2014-03-12 ES ES14778088T patent/ES2927675T3/es active Active
- 2014-03-12 SI SI201431991T patent/SI2968208T1/sl unknown
- 2014-03-12 RU RU2015143610A patent/RU2689984C2/ru active
- 2014-03-12 JP JP2016501395A patent/JP6530741B2/ja active Active
- 2014-03-12 BR BR112015022197-1A patent/BR112015022197B1/pt active IP Right Grant
- 2014-03-12 MY MYPI2015703166A patent/MY177740A/en unknown
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2015
- 2015-09-11 PH PH12015502075A patent/PH12015502075A1/en unknown
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2016
- 2016-05-09 US US15/149,478 patent/US9585863B2/en active Active
- 2016-06-23 HK HK16107350.1A patent/HK1219236A1/zh unknown
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2017
- 2017-01-30 US US15/419,133 patent/US10259780B2/en active Active
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2019
- 2019-03-20 US US16/359,446 patent/US11072579B2/en active Active
- 2019-05-17 JP JP2019093823A patent/JP2019147830A/ja active Pending
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2021
- 2021-07-23 US US17/383,707 patent/US11713292B2/en active Active
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2023
- 2023-06-19 US US18/337,299 patent/US20230416195A1/en active Pending
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