BR112014016197A8 - derivado de paroxetina - Google Patents
derivado de paroxetinaInfo
- Publication number
- BR112014016197A8 BR112014016197A8 BR112014016197A BR112014016197A BR112014016197A8 BR 112014016197 A8 BR112014016197 A8 BR 112014016197A8 BR 112014016197 A BR112014016197 A BR 112014016197A BR 112014016197 A BR112014016197 A BR 112014016197A BR 112014016197 A8 BR112014016197 A8 BR 112014016197A8
- Authority
- BR
- Brazil
- Prior art keywords
- paroxetine
- derivative
- paroxetine derivative
- retains
- abstract
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
resumo derivado de paroxetina um composto representado pela fórmula (1) ou um seu sal farmacologicamente aceitável retém os principais efeitos benéficos da paroxetina tendo ao mesmo tempo uma ação inibidora de cyp melhorada. em que r1 é um átomo de hidrogênio ou um grupo alquila c1-6.]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261592896P | 2012-01-31 | 2012-01-31 | |
| PCT/JP2013/051858 WO2013115163A1 (ja) | 2012-01-31 | 2013-01-29 | パロキセチン誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014016197A2 BR112014016197A2 (pt) | 2017-06-13 |
| BR112014016197A8 true BR112014016197A8 (pt) | 2017-07-04 |
Family
ID=48870749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014016197A BR112014016197A8 (pt) | 2012-01-31 | 2013-01-29 | derivado de paroxetina |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8933100B2 (pt) |
| EP (1) | EP2810942B1 (pt) |
| JP (1) | JP6055784B2 (pt) |
| KR (1) | KR101950057B1 (pt) |
| CN (1) | CN104039777B (pt) |
| AR (1) | AR089837A1 (pt) |
| AU (1) | AU2013216123B2 (pt) |
| BR (1) | BR112014016197A8 (pt) |
| CA (1) | CA2861479C (pt) |
| ES (1) | ES2576082T3 (pt) |
| IL (1) | IL233327A (pt) |
| IN (1) | IN2014CN04922A (pt) |
| MX (1) | MX355654B (pt) |
| RU (1) | RU2616610C2 (pt) |
| TW (1) | TW201334783A (pt) |
| WO (1) | WO2013115163A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE058819T2 (hu) * | 2015-09-02 | 2022-09-28 | Trevena Inc | 6-tagú aza-heterociklusos delta-opioid receptort moduláló vegyületek, felhasználásuk és elõállításuk módszerei |
| EP3582783B1 (en) | 2017-02-17 | 2023-06-07 | Trevena, Inc. | 7-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same |
| CN111533682B (zh) * | 2020-05-29 | 2022-03-01 | 清华大学 | 帕罗西汀及其类似物的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| KR100543614B1 (ko) * | 1997-06-10 | 2006-01-20 | 신톤 비.브이. | 4-페닐피페리딘 화합물 |
| IT1308629B1 (it) * | 1999-02-23 | 2002-01-09 | Recordati Chem Pharm | Processo per la produzione di paroxetina. |
| ES2396365T3 (es) * | 2005-07-29 | 2013-02-21 | Concert Pharmaceuticals Inc. | Nuevos derivados de benzo[D][1,3]-dioxol deuterados como inhibidores de la recaptación de serotonina |
| US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
-
2013
- 2013-01-29 CN CN201380005183.XA patent/CN104039777B/zh not_active Expired - Fee Related
- 2013-01-29 EP EP13744409.7A patent/EP2810942B1/en not_active Not-in-force
- 2013-01-29 BR BR112014016197A patent/BR112014016197A8/pt active Search and Examination
- 2013-01-29 AR ARP130100262A patent/AR089837A1/es unknown
- 2013-01-29 KR KR1020147021114A patent/KR101950057B1/ko active IP Right Grant
- 2013-01-29 CA CA2861479A patent/CA2861479C/en not_active Expired - Fee Related
- 2013-01-29 IN IN4922CHN2014 patent/IN2014CN04922A/en unknown
- 2013-01-29 ES ES13744409.7T patent/ES2576082T3/es active Active
- 2013-01-29 AU AU2013216123A patent/AU2013216123B2/en not_active Ceased
- 2013-01-29 JP JP2013556400A patent/JP6055784B2/ja not_active Expired - Fee Related
- 2013-01-29 MX MX2014007620A patent/MX355654B/es active IP Right Grant
- 2013-01-29 TW TW102103327A patent/TW201334783A/zh unknown
- 2013-01-29 WO PCT/JP2013/051858 patent/WO2013115163A1/ja active Application Filing
- 2013-01-29 US US13/752,638 patent/US8933100B2/en not_active Expired - Fee Related
- 2013-01-29 RU RU2014126321A patent/RU2616610C2/ru not_active IP Right Cessation
-
2014
- 2014-06-23 IL IL233327A patent/IL233327A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140117454A (ko) | 2014-10-07 |
| CA2861479C (en) | 2017-10-10 |
| EP2810942A4 (en) | 2015-07-01 |
| MX2014007620A (es) | 2014-09-15 |
| BR112014016197A2 (pt) | 2017-06-13 |
| RU2616610C2 (ru) | 2017-04-18 |
| WO2013115163A1 (ja) | 2013-08-08 |
| CN104039777B (zh) | 2016-03-02 |
| AU2013216123A1 (en) | 2014-07-17 |
| ES2576082T3 (es) | 2016-07-05 |
| EP2810942A1 (en) | 2014-12-10 |
| IL233327A (en) | 2016-03-31 |
| KR101950057B1 (ko) | 2019-02-19 |
| JPWO2013115163A1 (ja) | 2015-05-11 |
| AR089837A1 (es) | 2014-09-17 |
| IN2014CN04922A (pt) | 2015-09-18 |
| US8933100B2 (en) | 2015-01-13 |
| JP6055784B2 (ja) | 2016-12-27 |
| MX355654B (es) | 2018-04-26 |
| RU2014126321A (ru) | 2016-03-20 |
| IL233327A0 (en) | 2014-08-31 |
| TW201334783A (zh) | 2013-09-01 |
| AU2013216123B2 (en) | 2016-10-20 |
| US20130197033A1 (en) | 2013-08-01 |
| CA2861479A1 (en) | 2013-08-08 |
| CN104039777A (zh) | 2014-09-10 |
| EP2810942B1 (en) | 2016-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |