Nothing Special   »   [go: up one dir, main page]

BR0107699A - Processo de extração sem o uso de solventes e lipìdeos obtidos - Google Patents

Processo de extração sem o uso de solventes e lipìdeos obtidos

Info

Publication number
BR0107699A
BR0107699A BR0107699-0A BR0107699A BR0107699A BR 0107699 A BR0107699 A BR 0107699A BR 0107699 A BR0107699 A BR 0107699A BR 0107699 A BR0107699 A BR 0107699A
Authority
BR
Brazil
Prior art keywords
lipid
layer
extraction process
heavy
organic solvent
Prior art date
Application number
BR0107699-0A
Other languages
English (en)
Other versions
BR0107699B1 (pt
Inventor
George T Veeder Iii
Brian S Engelhardt
Swithin Patrick Adu-Peasah
Craig M Ruecker
Original Assignee
Omegatech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22647287&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0107699(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Omegatech Inc filed Critical Omegatech Inc
Publication of BR0107699A publication Critical patent/BR0107699A/pt
Publication of BR0107699B1 publication Critical patent/BR0107699B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/006—Refining fats or fatty oils by extraction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/02—Pretreatment
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/001—Refining fats or fatty oils by a combination of two or more of the means hereafter
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

"PROCESSO DE EXTRAçãO SEM O USO DE SOLVENTE E LIPìDIOS OBTIDOS". O presente resumo refere-se a uma patente de invenção para um processo de extração de lipídios de microorganismos, sem o uso de qualquer volume significativo de solvente orgânico não-polar, compreendendo, substancialmente: (a) o lisado de células de microorganismos para a produção de uma mistura celular lisada; (b) o tratamento da mistura celular lisada para produzir uma mistura de fase separada compreendendo uma camada pesada e uma camada leve, onde a referida camada pesada compreende uma solução aquosa e a referida camada leve compreende o referido lipídio; (c) a separação da referida camada pesada da referida camada; e (d) a obtenção do referido lipídio a partir da camada leve; e o lipídio obtido sendo substancialmente derivado de microorganismos com menos que 0,2 ppm de solvente orgânico residual não-polar.
BRPI0107699-0B1A 2000-01-19 2001-01-19 Processo de extração livre de solvente BR0107699B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17712500P 2000-01-19 2000-01-19
US60/177,125 2000-01-19
PCT/US2001/001806 WO2001053512A1 (en) 2000-01-19 2001-01-19 Solventless extraction process

Publications (2)

Publication Number Publication Date
BR0107699A true BR0107699A (pt) 2003-01-14
BR0107699B1 BR0107699B1 (pt) 2014-05-27

Family

ID=22647287

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0107699-0B1A BR0107699B1 (pt) 2000-01-19 2001-01-19 Processo de extração livre de solvente

Country Status (24)

Country Link
US (8) US6750048B2 (pt)
EP (4) EP2295594B1 (pt)
JP (5) JP4020642B2 (pt)
KR (8) KR101429236B1 (pt)
CN (1) CN100460513C (pt)
AT (1) ATE485385T1 (pt)
AU (7) AU780619B2 (pt)
BR (1) BR0107699B1 (pt)
CA (2) CA2772540A1 (pt)
CZ (1) CZ303446B6 (pt)
DE (1) DE60143287D1 (pt)
DK (1) DK1252324T3 (pt)
ES (3) ES2735987T3 (pt)
HK (1) HK1050716A1 (pt)
HU (1) HUP0300556A3 (pt)
IL (5) IL150772A0 (pt)
MX (4) MX350779B (pt)
NO (2) NO20023449L (pt)
NZ (1) NZ520287A (pt)
PL (1) PL356587A1 (pt)
PT (1) PT1252324E (pt)
RU (1) RU2336307C2 (pt)
WO (1) WO2001053512A1 (pt)
ZA (1) ZA200205790B (pt)

Families Citing this family (204)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078051B1 (en) 1998-08-11 2006-07-18 Natural Asa Conjugated linoleic acid alkyl esters in feedstuffs and food
AU764699B2 (en) 1998-03-17 2003-08-28 Conlinco, Inc. Conjugated linoleic acid compositions
US7776353B1 (en) 1998-03-17 2010-08-17 Aker Biomarine Asa Conjugated linoleic acid compositions
US7101914B2 (en) 1998-05-04 2006-09-05 Natural Asa Isomer enriched conjugated linoleic acid compositions
NZ520287A (en) 2000-01-19 2004-01-30 Martek Biosciences Corp Solventless extraction process
WO2001077271A2 (en) * 2000-04-06 2001-10-18 Conlinco, Inc. Conjugated linoleic acid compositions
EP1274320A2 (en) 2000-04-18 2003-01-15 Natural AS Conjugated linoleic acid powder
EP1178118A1 (en) * 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
US6677470B2 (en) 2001-11-20 2004-01-13 Natural Asa Functional acylglycerides
WO2003049832A1 (en) * 2001-12-12 2003-06-19 Martek Biosciences Boulder Corp. Extraction and winterization of lipids from oilseed and microbial sources
EP2921155B1 (en) 2002-05-03 2020-01-08 DSM IP Assets B.V. Methods for producing high-quality lipids by enzymatic liberation from biomass
US6743931B2 (en) 2002-09-24 2004-06-01 Natural Asa Conjugated linoleic acid compositions
WO2005035775A1 (en) 2003-10-02 2005-04-21 Martek Biosciences Corporation Production of high levels of dha in microalgae using modified amounts of chloride and potassium
US7566570B2 (en) 2004-01-26 2009-07-28 Martek Biosciences Corporation Method for the separation of phospholipids from phospholipid-containing materials
CN101218352B (zh) 2005-03-18 2013-09-04 米克罗比亚公司 产油酵母和真菌中类胡萝卜素的产生
US8048652B2 (en) * 2005-05-12 2011-11-01 Martek Biosciences Corporation Biomass hydrolysate and uses and production thereof
ES2729976T3 (es) * 2005-06-07 2019-11-07 Dsm Nutritional Products Ag Microorganismos eucariotas para la producción de lípidos y antioxidantes
MX300085B (es) 2005-07-01 2012-06-08 Martek Biosciences Corp Producto oleoso que contiene acido graso poli-insaturado y usos y produccion del mismo.
US8298548B2 (en) 2007-07-18 2012-10-30 Solazyme, Inc. Compositions for improving the health and appearance of skin
US8277849B2 (en) 2006-01-19 2012-10-02 Solazyme, Inc. Microalgae-derived compositions for improving the health and appearance of skin
US20100242345A1 (en) * 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
US8110670B2 (en) * 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
EP2044208A4 (en) * 2006-07-05 2012-02-22 Photonz Corp Ltd PRODUCTION OF EPA AND ULTRA PURE POLAR LIPIDS FROM A BROADLY HETERATROPHE CULTURE
JP4854418B2 (ja) * 2006-07-28 2012-01-18 花王株式会社 ドデカヒドロ−３ａ，６，６，９ａ−テトラメチルナフト［２，１−ｂ］フラン原料の製造方法
WO2008129358A2 (en) * 2006-08-01 2008-10-30 Ocean Nutrition Canada Ltd. Oil producing microbes and methods of modification thereof
WO2008042338A2 (en) 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US8262776B2 (en) * 2006-10-13 2012-09-11 General Atomics Photosynthetic carbon dioxide sequestration and pollution abatement
US8088614B2 (en) * 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
HUE028692T2 (en) * 2007-04-03 2016-12-28 Du Pont Multi-uses and their use in the production of polyunsaturated fatty acids
US8476059B2 (en) 2007-06-01 2013-07-02 Solazyme, Inc. Sucrose feedstock utilization for oil-based fuel manufacturing
WO2008155410A1 (en) * 2007-06-21 2008-12-24 Novozymes A/S Production of lipids containing poly-unsaturated fatty acids
JP2010532418A (ja) * 2007-06-29 2010-10-07 マーテック バイオサイエンシーズ コーポレーション 多価不飽和脂肪酸のエステルの製造方法および精製方法
CN101874117A (zh) * 2007-09-12 2010-10-27 马太克生物科学公司 生物油及其制备与应用
WO2009042950A1 (en) * 2007-09-27 2009-04-02 Ls9, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
US8343753B2 (en) * 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
CA2704371A1 (en) * 2007-11-01 2009-05-07 Wake Forest University School Of Medicine Compositions and methods for prevention and treatment of mammalian diseases
WO2009149470A1 (en) 2008-06-06 2009-12-10 Aurora Biofuels, Inc. Vcp-based vectors for algal cell transformation
US20100022393A1 (en) * 2008-07-24 2010-01-28 Bertrand Vick Glyphosate applications in aquaculture
WO2010036334A1 (en) * 2008-09-23 2010-04-01 LiveFuels, Inc. Systems and methods for producing biofuels from algae
US20100236137A1 (en) * 2008-09-23 2010-09-23 LiveFuels, Inc. Systems and methods for producing eicosapentaenoic acid and docosahexaenoic acid from algae
US20100303989A1 (en) 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US20100297325A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Egg Products Containing Microalgae
US9896642B2 (en) 2008-10-14 2018-02-20 Corbion Biotech, Inc. Methods of microbial oil extraction and separation
US20100303961A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Methods of Inducing Satiety
US20100303957A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. Edible Oil and Processes for Its Production from Microalgae
US8927522B2 (en) 2008-10-14 2015-01-06 Solazyme, Inc. Microalgal polysaccharide compositions
BRPI0920280B8 (pt) * 2008-10-14 2022-11-16 Corbion Biotech Inc Composição alimentícia, e, método para fabricar uma composição alimentícia
US20100297323A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Gluten-free Foods Containing Microalgae
US20100297295A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Microalgae-Based Beverages
US20100297331A1 (en) * 2008-10-14 2010-11-25 Solazyme, Inc. Reduced Fat Foods Containing High-Lipid Microalgae with Improved Sensory Properties
US20100303990A1 (en) * 2008-10-14 2010-12-02 Solazyme, Inc. High Protein and High Fiber Algal Food Materials
US8809037B2 (en) 2008-10-24 2014-08-19 Bioprocessh20 Llc Systems, apparatuses and methods for treating wastewater
WO2010054322A1 (en) 2008-11-07 2010-05-14 Solazyme, Inc. Cosmetic compositions comprising microalgal components
WO2010059598A1 (en) * 2008-11-18 2010-05-27 LiveFuels, Inc. Methods for producing fish with high lipid content
CA3037322A1 (en) 2008-11-28 2010-06-03 Corbion Biotech, Inc. Production of tailored oils in heterotrophic microorganisms
WO2010077694A1 (en) * 2008-12-08 2010-07-08 Sapphire Energy, Inc. Removal of nitrogen from a chlorophyll or pheophytin containing biomass
US8940340B2 (en) * 2009-01-22 2015-01-27 Aurora Algae, Inc. Systems and methods for maintaining the dominance of Nannochloropsis in an algae cultivation system
EP2939671A1 (en) 2009-02-02 2015-11-04 DSM IP Assets B.V. Methods for improving cognitive function and decreasing heart rate
US8143051B2 (en) * 2009-02-04 2012-03-27 Aurora Algae, Inc. Systems and methods for maintaining the dominance and increasing the biomass production of nannochloropsis in an algae cultivation system
SE534278C2 (sv) * 2009-02-17 2011-06-28 Alfa Laval Corp Ab Ett kontinuerligt förfarande för isolering av oljor från alger eller mikroorganismer
WO2010107415A1 (en) 2009-03-19 2010-09-23 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8207363B2 (en) * 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8476060B2 (en) * 2009-04-13 2013-07-02 Board Of Regents, The University Of Texas System Process for separating lipids from a biomass
WO2010121094A1 (en) 2009-04-17 2010-10-21 Livefuels. Inc. Systems and methods for culturing algae with bivalves
US20100297749A1 (en) * 2009-04-21 2010-11-25 Sapphire Energy, Inc. Methods and systems for biofuel production
EP2421944B1 (en) * 2009-04-22 2015-06-17 Robert Fulton Fluidizable algae-based powdered fuel and methods for making and using same
EP2425007A4 (en) 2009-04-27 2013-01-02 Ls9 Inc PREPARATION OF FATTY ACID ESTERS
US9187778B2 (en) 2009-05-04 2015-11-17 Aurora Algae, Inc. Efficient light harvesting
WO2010138620A1 (en) 2009-05-26 2010-12-02 Solazyme, Inc. Fractionation of oil-bearing microbial biomass
US8865468B2 (en) * 2009-10-19 2014-10-21 Aurora Algae, Inc. Homologous recombination in an algal nuclear genome
US8809046B2 (en) 2011-04-28 2014-08-19 Aurora Algae, Inc. Algal elongases
US8865452B2 (en) * 2009-06-15 2014-10-21 Aurora Algae, Inc. Systems and methods for extracting lipids from wet algal biomass
US8769867B2 (en) * 2009-06-16 2014-07-08 Aurora Algae, Inc. Systems, methods, and media for circulating fluid in an algae cultivation pond
US9101942B2 (en) * 2009-06-16 2015-08-11 Aurora Algae, Inc. Clarification of suspensions
US8747930B2 (en) * 2009-06-29 2014-06-10 Aurora Algae, Inc. Siliceous particles
US20100325948A1 (en) * 2009-06-29 2010-12-30 Mehran Parsheh Systems, methods, and media for circulating and carbonating fluid in an algae cultivation pond
CN101585759B (zh) * 2009-07-08 2012-05-23 内蒙古金达威药业有限公司 从双鞭甲藻发酵液中提取dha不饱和脂肪酸的方法
WO2011006144A1 (en) 2009-07-10 2011-01-13 Martek Biosciences Corporation Methods of treating and preventing neurological disorders using docosahexaenoic acid
WO2011011463A2 (en) * 2009-07-20 2011-01-27 Aurora Biofuels, Inc. Manipulation of an alternative respiratory pathway in photo-autotrophs
US20110082205A1 (en) 2009-10-01 2011-04-07 Panker Cynthia A Docosahexaenoic Acid Gel Caps
US8765983B2 (en) * 2009-10-30 2014-07-01 Aurora Algae, Inc. Systems and methods for extracting lipids from and dehydrating wet algal biomass
US8748160B2 (en) * 2009-12-04 2014-06-10 Aurora Alage, Inc. Backward-facing step
US20110195449A1 (en) 2009-12-28 2011-08-11 Martek Biosciences Corporation Recombinant Thraustochytrids that Grow on Sucrose, and Compositions, Methods of Making, and Uses Thereof
CN102906270B (zh) * 2009-12-28 2016-06-22 Dsmip资产公司 在木糖上生长的重组破囊壶菌和其组合物、制备方法及用途
EA031136B1 (ru) * 2010-01-19 2018-11-30 ДСМ АйПи АССЕТС Б.В. Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции жирных кислот и способы их получения и применения
US8303818B2 (en) * 2010-06-24 2012-11-06 Streamline Automation, Llc Method and apparatus using an active ionic liquid for algae biofuel harvest and extraction
US8313648B2 (en) 2010-04-06 2012-11-20 Heliae Development, Llc Methods of and systems for producing biofuels from algal oil
WO2011127127A2 (en) 2010-04-06 2011-10-13 Arizona Board Of Regents For And On Behalf Of Arizona State University Extraction with fractionation of oil and co-products from oleaginous material
US8475660B2 (en) 2010-04-06 2013-07-02 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US8211308B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of polar lipids by a two solvent method
BR112012025584A2 (pt) 2010-04-06 2015-09-22 Heliae Dev Llc extração seletiva de proteínas de algas de água doce
US8115022B2 (en) 2010-04-06 2012-02-14 Heliae Development, Llc Methods of producing biofuels, chlorophylls and carotenoids
US8273248B1 (en) 2010-04-06 2012-09-25 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
US8202425B2 (en) 2010-04-06 2012-06-19 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
US8211309B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of proteins by a two solvent method
US8308951B1 (en) 2010-04-06 2012-11-13 Heliae Development, Llc Extraction of proteins by a two solvent method
US10125331B2 (en) * 2010-04-29 2018-11-13 Advanced Energy Development Renewable oil refining processes
SG10201504197SA (en) 2010-05-28 2015-06-29 Solazyme Inc Food Compositions Comprising Tailored Oils
EP2576801B1 (en) * 2010-06-01 2019-10-02 DSM IP Assets B.V. Extraction of lipid from cells and products therefrom
NL2004832C2 (en) * 2010-06-07 2011-12-08 Evodos B V Separating biomass from an aqueous medium.
SG185578A1 (en) 2010-06-14 2013-01-30 Io Mega Holding Corp Methods for the production of algae derived oils
US8906236B2 (en) 2010-07-26 2014-12-09 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds and nutrients from biomass
BR112013002003A2 (pt) 2010-07-26 2019-09-24 Sapphire Energy Inc processo para recuperação de compostos oleaginosos de biomassa
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
CN103180422A (zh) 2010-09-21 2013-06-26 国际壳牌研究有限公司 含微生物油和微生物物质的混合物的分离方法
KR101964886B1 (ko) 2010-11-03 2019-04-03 테라비아 홀딩스 인코포레이티드 유동점이 낮은 미생물 오일, 이 오일로 제조된 유전성 유체 및 관련 방법
US20120329138A1 (en) 2010-12-23 2012-12-27 Shell Oil Company Process for separation of a mixture containing a microbial substance and a liquid
US8722359B2 (en) 2011-01-21 2014-05-13 Aurora Algae, Inc. Genes for enhanced lipid metabolism for accumulation of lipids
CN102617431B (zh) * 2011-01-28 2013-09-25 天津滨海索尔特生物技术中心有限公司 用无机碱提取盐藻中的β-胡萝卜素的方法
AU2012212079B2 (en) 2011-02-02 2016-07-28 Corbion Biotech, Inc. Tailored oils produced from recombinant oleaginous microorganisms
MX2013009431A (es) * 2011-02-16 2014-07-30 Solix Biosystems Inc Composiciones y metodos para extraccion por lixiviacion de microorganismos.
US8926844B2 (en) 2011-03-29 2015-01-06 Aurora Algae, Inc. Systems and methods for processing algae cultivation fluid
US8569530B2 (en) 2011-04-01 2013-10-29 Aurora Algae, Inc. Conversion of saponifiable lipids into fatty esters
JP2014519810A (ja) 2011-04-28 2014-08-21 オーロラ アルギー，インコーポレイテッド 藻類のデサチュラーゼ
US8752329B2 (en) 2011-04-29 2014-06-17 Aurora Algae, Inc. Optimization of circulation of fluid in an algae cultivation pond
US8846352B2 (en) 2011-05-06 2014-09-30 Solazyme, Inc. Genetically engineered microorganisms that metabolize xylose
US9487716B2 (en) 2011-05-06 2016-11-08 LiveFuels, Inc. Sourcing phosphorus and other nutrients from the ocean via ocean thermal energy conversion systems
US20140099684A1 (en) * 2011-05-26 2014-04-10 Council Of Scientific & Industrial Research Engine worthy fatty acid methyl ester (biodiesel) from naturally occuring marine microalgal mats and marine microalgae cultured in open salt pans together with value addition of co-products
FR2975705B1 (fr) 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
US8365462B2 (en) 2011-05-31 2013-02-05 Heliae Development, Llc V-Trough photobioreactor systems
USD679965S1 (en) 2011-06-10 2013-04-16 Heliae Development, Llc Aquaculture vessel
USD682637S1 (en) 2011-06-10 2013-05-21 Heliae Development, Llc Aquaculture vessel
USD661164S1 (en) 2011-06-10 2012-06-05 Heliae Development, Llc Aquaculture vessel
MX351174B (es) 2011-07-21 2017-10-04 Dsm Ip Assets Bv Microorganismos que producen acido eicosapentaenoico, composiciones de acidos grasos,y metodos para prepararlos y usos de los mismos.
MX342216B (es) 2011-07-21 2016-09-20 Dsm Ip Assets Bv Composiciones de acidos grasos.
WO2013024174A1 (en) 2011-08-18 2013-02-21 Dsm Ip Assets B.V. Dha triglyceride, dha free fatty acid, and dha ethyl ester emulsions, and methods of treating spinal cord injury
KR20240035899A (ko) 2011-11-01 2024-03-18 디에스엠 아이피 어셋츠 비.브이. 산화적으로 안정한 다중불포화된 지방산 함유 오일
WO2013075116A2 (en) 2011-11-17 2013-05-23 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
CN103131529B (zh) * 2011-11-23 2016-02-24 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
CN110358686A (zh) 2012-04-18 2019-10-22 柯碧恩生物技术公司 定制油
WO2013166065A1 (en) 2012-04-30 2013-11-07 Aurora Algae, Inc. ACP Promoter
CN103421595A (zh) * 2012-05-25 2013-12-04 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
WO2014004999A1 (en) * 2012-06-29 2014-01-03 BP Biofuels UK Limited Process for separation of renewable materials from microorganisms
CN103589503B (zh) * 2012-08-13 2015-09-30 丰益(上海)生物技术研发中心有限公司 一种高效提取微生物油脂的方法
KR101470078B1 (ko) * 2012-08-21 2014-12-08 현대자동차주식회사 이산화탄소 포집ㆍ고정ㆍ전환을 통한 온실가스 감축 및 부가가치화 방법
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
US9567615B2 (en) 2013-01-29 2017-02-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
US9816079B2 (en) 2013-01-29 2017-11-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
EP2953480B1 (de) * 2013-02-05 2020-06-03 Evonik Operations GmbH Verbesserung der bioverfügbarkeit von wertstoffen aus mikroorganismen
EP2762009A1 (de) * 2013-02-05 2014-08-06 Evonik Industries AG Verbesserung der Bioverfügbarkeit von Wertstoffen aus Mikroorganismen
EP2970926B1 (en) 2013-03-13 2018-01-31 DSM Nutritional Products AG Engineering microorganisms
US9266973B2 (en) 2013-03-15 2016-02-23 Aurora Algae, Inc. Systems and methods for utilizing and recovering chitosan to process biological material
US9290749B2 (en) 2013-03-15 2016-03-22 Solazyme, Inc. Thioesterases and cells for production of tailored oils
US9783836B2 (en) 2013-03-15 2017-10-10 Terravia Holdings, Inc. Thioesterases and cells for production of tailored oils
US9597280B2 (en) 2013-05-15 2017-03-21 Terravia Holdings, Inc. Cosmetic compositions comprising microalgal oil
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
JP6517196B2 (ja) 2013-10-04 2019-05-22 テラヴィア ホールディングス， インコーポレイテッド 調整油
KR102143001B1 (ko) 2013-11-01 2020-08-11 에스케이이노베이션 주식회사 초음속 분산기를 이용한 유질 미생물 파쇄 공정 및 이를 이용한 바이오 오일의 제조방법
PL3082793T3 (pl) 2013-12-20 2020-10-05 Dsm Ip Assets B.V. Sposoby otrzymywania oleju drobnoustrojowego z komórek drobnoustrojowych
CN105849242A (zh) 2013-12-20 2016-08-10 玛拉可再生能源公司 从微生物中回收油的方法
JP2017504318A (ja) 2013-12-20 2017-02-09 ディーエスエム アイピー アセッツ ビー．ブイ． 微生物細胞から微生物油を入手するための方法
SG11201605066WA (en) * 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
US11001782B2 (en) * 2013-12-20 2021-05-11 Dsm Nutritional Products Ag Methods of recovering oil from microorganisms
AR098895A1 (es) 2013-12-20 2016-06-22 Dsm Ip Assets Bv Proceso para obtener aceite microbiano a partir de células microbianas
TWI708836B (zh) 2013-12-20 2020-11-01 荷蘭商Ｄｓｍ智慧財產有限公司 用於從微生物細胞獲得微生物油之方法（二）
US9969990B2 (en) 2014-07-10 2018-05-15 Corbion Biotech, Inc. Ketoacyl ACP synthase genes and uses thereof
WO2016014968A1 (en) 2014-07-24 2016-01-28 Solazyme, Inc. Variant thioesterases and methods of use
CN107208103A (zh) 2014-09-18 2017-09-26 泰拉瑞亚控股公司 酰基‑acp硫酯酶及其突变体
WO2016050556A1 (de) 2014-10-02 2016-04-07 Evonik Degussa Gmbh Verfahren zur anzucht von tieren
ES2870093T3 (es) 2014-10-02 2021-10-26 Evonik Operations Gmbh Biomasa que contiene PUFA con estabilidad celular elevada y su empleo para la producción de piensos
CN106793798A (zh) 2014-10-02 2017-05-31 赢创德固赛有限公司 具有高抗磨损性和高水稳定性的含pufa的饲料
DK3200606T3 (da) 2014-10-02 2021-06-21 Evonik Operations Gmbh Fremgangsmåde til fremstilling af et fodermiddel, der indeholder pufa'er, ved ekstrusion af en biomasse, der indeholder pufa'er, af typen labyrinthulomycetes
CN107106628B (zh) 2014-12-22 2021-01-12 荷兰联合利华有限公司 毛发组合物
KR20160096478A (ko) * 2015-02-05 2016-08-16 주식회사 이코원 탄소 발열 모듈 및 이를 이용한 탄소 발열 튀김기
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
JP6814148B2 (ja) 2015-03-31 2021-01-13 フレゼニウス カービ ドイチュラント ゲーエムベーハー 非経口投与用のエマルション
US20160298104A1 (en) * 2015-04-07 2016-10-13 Decant Treatment Systems, Llc Method for electrical treatment of fluid medium containing biological matter and a system for its implementation
EP3297606B1 (en) 2015-05-22 2020-07-22 Fresenius Kabi Deutschland GmbH Vitamin a for parenteral administration
WO2016188876A1 (en) 2015-05-22 2016-12-01 Fresenius Kabi Deutschland Gmbh Vitamin a for parenteral administration
US9951326B2 (en) 2015-07-13 2018-04-24 MARA Renewables Corporation Enhancing microbial metabolism of C5 organic carbon
ITUB20152958A1 (it) 2015-08-06 2017-02-06 Eni Spa Metodo per concentrare una sospensione cellulare comprendente una biomassa mucillaginosa di lieviti oleaginosi.
KR102680258B1 (ko) * 2016-04-18 2024-07-02 서울바이오시스 주식회사 공기 청정기
WO2017194683A1 (en) 2016-05-12 2017-11-16 Dsm Ip Assets B.V. Method of increasing omega-3 polyunsaturated fatty acids production in microalgae
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
US11419350B2 (en) 2016-07-01 2022-08-23 Corbion Biotech, Inc. Feed ingredients comprising lysed microbial cells
BR112019000435A2 (pt) 2016-07-13 2019-04-30 Evonik Degussa Gmbh método para separar lipídios de uma biomassa contendo lipídios lisados
AU2017296386B2 (en) * 2016-07-13 2021-11-18 Dsm Ip Assets B.V. Method for extracting a microbial oil comprising polyunsaturated fatty acids from a fermentation broth containing oleaginous microorganisms
US11406614B2 (en) 2016-10-11 2022-08-09 Fresenius Kabi Deutschland Gmbh Composition comprising EPA and DHA for an enhanced efficacy of anticancer agents
CA3048289C (en) * 2016-12-27 2023-09-26 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
WO2018122057A1 (en) * 2016-12-27 2018-07-05 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
US11814665B2 (en) 2017-08-17 2023-11-14 Evonik Operations Gmbh Enhanced production of lipids by limitation of at least two limiting nutrient sources
WO2019034354A1 (en) 2017-08-17 2019-02-21 Evonik Degussa Gmbh ENHANCED PRODUCTION OF LIPIDS BY LIMITING AT LEAST TWO SOURCES OF NUTRIENT LIMITING
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019122030A1 (en) * 2017-12-22 2019-06-27 Dsm Ip Assets B.V. Method of separating lipids from a lysed lipids containing biomass
WO2019191545A1 (en) * 2018-03-30 2019-10-03 Dsm Ip Assets B.V. Method of reducing emulsion by broth washing
CN112004935B (zh) * 2018-03-30 2024-05-14 帝斯曼知识产权资产管理有限公司 获得微生物油的方法和通过维持低的碳水化合物浓度来减少乳液的方法
CA3101855C (en) 2018-05-15 2023-06-20 Evonik Operations Gmbh Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
WO2019219396A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
US20210290526A1 (en) 2018-07-03 2021-09-23 Fresenius Kabi Deutschland Gmbh Lipid emulsion for parenteral administration
FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
FR3085962B1 (fr) 2018-09-14 2021-06-18 Fermentalg Procede d'extracton d'une huile riche en pufa
BR112021008842A2 (pt) 2018-11-09 2021-08-17 Evonik Operations Gmbh método para produzir uma biomassa com um teor aumentado de ácidos graxos poli-insaturados
EP3877535A1 (de) * 2018-11-09 2021-09-15 Evonik Operations GmbH Verfahren zur herstellung einer leicht aufschliessbaren biomasse mit erhöhtem gehalt an polyungesättigten fettsäuren
CN113543653A (zh) 2018-12-14 2021-10-22 帝斯曼知识产权资产管理有限公司 具有增强的适口性的含有多不饱和脂肪酸的食品成分及其制造方法
EP4076384B1 (de) 2019-12-20 2024-11-13 Fresenius Kabi Austria GmbH Verfahren zur herstellung von öl-in-wasser-emulsionen
CN111235035A (zh) * 2019-12-30 2020-06-05 嘉必优生物技术（武汉）股份有限公司 一种裂殖壶菌突变株及其用于制备二十二碳六烯酸油脂的方法和应用
FR3111912A1 (fr) 2020-06-24 2021-12-31 Fermentalg Procédé de culture de microorganismes pour l’accumulation de lipides
FR3130842A1 (fr) 2021-12-22 2023-06-23 CarbonWorks Procede de captation des phytotoxines dans un reacteur biologique
WO2023175141A1 (en) * 2022-03-18 2023-09-21 Purac Biochem B.V. Method for reducing fermentation broth viscosity
WO2023220060A1 (en) * 2022-05-11 2023-11-16 C16 Biosciences, Inc. Enzymatic lysis for extraction of bioproducts from yeast
WO2024119170A2 (en) 2022-12-02 2024-06-06 Dsm Ip Assets B.V. Fermentatively-produced retinoid containing compositions, and the methdos of making and using the same
KR20240109876A (ko) * 2023-01-05 2024-07-12 주식회사 밤비콜라 커피박을 이용한 칸디다 봄비콜라의 배양방법 및 이로부터의 배양물

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2753362A (en) 1951-05-18 1956-07-03 Standard Brands Inc Process of extracting lipids from plant and animal tissue
GB808128A (en) * 1955-12-01 1959-01-28 Nat Res Dev A method of increasing the fatty contents of such micro-organisms as yeasts, bacteria and moulds
US3089821A (en) 1959-10-28 1963-05-14 Merck & Co Inc Process for the preparation of lipids
DE2056896B2 (de) * 1970-02-18 1979-12-06 Veb Schwermaschinenbau Kombinat Ernst Thaelmann Magdeburg, Ddr 3011 Magdeburg Verfahren zur gleichzeitigen Gewinnung von Fett und Protein aus pflanzlichen, ölhaltigen Rohstoffen und Zwischenprodukten
US3878232A (en) * 1970-09-28 1975-04-15 Staley Mfg Co A E Extraction process to improve the quality and yield of crude vegetable oils
US4504473A (en) * 1982-06-30 1985-03-12 Ribi Immunochem Research, Inc. Pyridine soluble extract of a microorganism
DE3248167A1 (de) * 1982-12-27 1984-06-28 Wintershall Ag, 3100 Celle Trehaloselipidtetraester
US4792418A (en) 1985-08-14 1988-12-20 Century Laboratories, Inc. Method of extraction and purification of polyunsaturated fatty acids from natural sources
JPS6244170A (ja) 1985-08-19 1987-02-26 Agency Of Ind Science & Technol モルテイエレラ属糸状菌体の超臨界流体による抽出方法
US4680314A (en) 1985-08-30 1987-07-14 Microbio Resources, Inc. Process for producing a naturally-derived carotene/oil composition by direct extraction from algae
JPH0634730B2 (ja) * 1986-06-16 1994-05-11 鐘淵化学工業株式会社 パルミトレイン酸の製造法
DK199887D0 (da) 1987-04-15 1987-04-15 Danisco Bioteknologi As Gaerstamme
FR2621327B1 (fr) 1987-10-06 1990-01-05 Commissariat Energie Atomique Procede de production et d'extraction de polysaccharides a partir d'une culture de porphyridium cruentum et dispositif pour la mise en oeuvre du procede
JPH0198494A (ja) 1987-10-09 1989-04-17 Agency Of Ind Science & Technol バイオリアクター
US6451567B1 (en) 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5340594A (en) 1988-09-07 1994-08-23 Omegatech Inc. Food product having high concentrations of omega-3 highly unsaturated fatty acids
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5173409A (en) 1989-12-08 1992-12-22 Ecogen Inc. Recovery of bt endotoxin protein from lysed cell mixtures
FR2656874B1 (fr) * 1990-01-11 1992-04-03 Commissariat Energie Atomique Procede de production et d'extraction d'anti-oxydants a partir d'une culture de micro-organismes et photobioreacteur pour la mise en óoeuvre de ce procede.
US5407957A (en) 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US5658767A (en) * 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
US6270828B1 (en) 1993-11-12 2001-08-07 Cargrill Incorporated Canola variety producing a seed with reduced glucosinolates and linolenic acid yielding an oil with low sulfur, improved sensory characteristics and increased oxidative stability
FR2686619B1 (fr) * 1992-01-28 1995-07-13 Commissariat Energie Atomique Procede de production selective de lipides poly-insatures a partir d'une culture de micro-algues du type porphyridium et cuve utilisee dans ce procede.
US5476787A (en) 1992-04-24 1995-12-19 Director-General Of Agency Of Industrial Science And Technology Method of removing nitrogen impurities from water using hydrocarbon-producing microalga
DE4219360C2 (de) * 1992-06-12 1994-07-28 Milupa Ag Verfahren zur Gewinnung von Lipiden mit einem hohen Anteil von langkettig-hochungesättigten Fettsäuren
JPH072724A (ja) * 1993-03-24 1995-01-06 Nippon Sanso Kk １３ｃ標識アラキドン酸とその誘導体及び製造方法
JPH06340577A (ja) * 1993-03-24 1994-12-13 Nippon Sanso Kk １３ｃ標識イコサペンタエン酸とその誘導体及び製造方法
FR2719222B1 (fr) * 1994-05-02 1996-06-21 Rocher Yves Biolog Vegetale Vésicules lipidiques, leur procédé de fabrication et leurs applications.
US5928696A (en) * 1994-08-16 1999-07-27 Dr. Frische Gmbh Process for extracting native products which are not water-soluble from native substance mixtures by centrifugal force
US5583019A (en) 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
JP2764572B2 (ja) * 1995-04-17 1998-06-11 工業技術院長 ドコサヘキサエン酸生産能を有する新規微生物及びそれを用いたドコサヘキサエン酸の製造方法
WO1996033263A1 (fr) 1995-04-17 1996-10-24 JAPAN, represented by DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY Nouveaux micro-organismes capables de produire des acides gras hautement insatures et procede de production d'acides gras hautement insatures utilisant ces micro-organismes
EP0741183B1 (fr) * 1995-05-04 1999-03-24 Societe Des Produits Nestle S.A. Procédé de fractionnement d'acides gras
GB9514649D0 (en) 1995-07-18 1995-09-13 Zeneca Ltd Extraction of triglycerides from microorganisms
JP3985035B2 (ja) * 1995-09-14 2007-10-03 独立行政法人産業技術総合研究所 （ｎ−６）系ドコサペンタエン酸含有油脂ならびに該油脂の製造方法および用途
US6255505B1 (en) 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
EP0969086A1 (en) 1996-07-03 2000-01-05 Sagami Chemical Research Center Microorganisms producing docosahexaenoic acid and process for the production of docosahexaenoic acid
AU723553C (en) 1996-07-23 2005-04-14 Nagase & Co., Ltd. Process for preparing docosahexaenoic acid and docosapentaenoic acid
US5951875A (en) 1996-12-20 1999-09-14 Eastman Chemical Company Adsorptive bubble separation methods and systems for dewatering suspensions of microalgae and extracting components therefrom
EP0972844B1 (en) * 1997-03-04 2008-09-17 Suntory Limited Process for preparing highly unsaturated fatty acid and lipid containing highly unsaturated fatty acid
WO1998050574A1 (en) * 1997-05-02 1998-11-12 Dsm N.V. Isolation of carotenoid crystals from microbial biomass
EP1905309A1 (en) 1997-05-27 2008-04-02 SemBioSys Genetics Inc. Uses of oil bodies
US7585645B2 (en) 1997-05-27 2009-09-08 Sembiosys Genetics Inc. Thioredoxin and thioredoxin reductase containing oil body based products
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
JP3836231B2 (ja) * 1997-10-17 2006-10-25 日本化学飼料株式会社 ホタテガイ中腸腺から得られる高度不飽和脂肪酸含有油及びその製造方法
WO1999025157A1 (fr) 1997-11-12 1999-05-20 Mitsubishi Denki Kabushiki Kaisha Dispositif electroluminescent et structure destinee au blindage de celui-ci
JP2000041684A (ja) 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なｄ−アミノアシラーゼおよびその製造方法、並びに該ｄ−アミノアシラーゼを利用したｄ−アミノ酸の製造方法
FR2782921B1 (fr) 1998-09-09 2002-09-20 Dior Christian Parfums Extrait lipidique de l'algue skeletonema, procede de preparation et utilisation dans des domaines cosmetique et pharmaceutique, notamment dermatologique
US6166231A (en) 1998-12-15 2000-12-26 Martek Biosciences Corporation Two phase extraction of oil from biomass
JP2000245492A (ja) 1999-03-02 2000-09-12 Kyowa Hakko Kogyo Co Ltd 微生物抽出脂質
US6344349B1 (en) 1999-12-06 2002-02-05 Decant Technologies Llc Process and system for electrical extraction of intracellular matter from biological matter
NZ520287A (en) 2000-01-19 2004-01-30 Martek Biosciences Corp Solventless extraction process
CA2398053C (en) 2000-04-12 2011-02-01 Westfalia Separator Industry Gmbh Method for the fractionation of oil and polar lipid-containing native raw materials
DE10018213A1 (de) 2000-04-12 2001-10-25 Westfalia Separator Ind Gmbh Verfahren zur Fraktionierung von öl-und lecithinhaltigen nativen Rohstoffen
EP1178118A1 (en) * 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
US20060060520A1 (en) 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
AU2002323409A1 (en) 2001-08-24 2003-03-10 Martek Biosciences Boulder Corporation Products containing highly unsaturated fatty acids for use by women and their children during stages of preconception, pregnancy and lactation/post-partum
WO2003049832A1 (en) 2001-12-12 2003-06-19 Martek Biosciences Boulder Corp. Extraction and winterization of lipids from oilseed and microbial sources
EP2921155B1 (en) 2002-05-03 2020-01-08 DSM IP Assets B.V. Methods for producing high-quality lipids by enzymatic liberation from biomass
EP1513922B2 (en) 2002-06-19 2015-09-23 DSM IP Assets B.V. Pasteurisation process for microbial cells and microbial oil
WO2005035775A1 (en) 2003-10-02 2005-04-21 Martek Biosciences Corporation Production of high levels of dha in microalgae using modified amounts of chloride and potassium
EP1731616A4 (en) 2004-03-01 2011-08-17 Suntory Holdings Ltd PROCESS FOR THE PRODUCTION OF PHOSPHOLIPID CONTAINING LONG CHAIN POLYUNSATURATED FATTY ACID AS A COMPONENT AND USE THEREOF
KR20070015178A (ko) 2004-04-27 2007-02-01 백스터 인터내셔널 인코포레이티드 교반-탱크 반응기 시스템
EP1597976B1 (en) 2004-05-21 2013-01-30 Nestec S.A. Use of polyol esters of fatty acids in aerated frozen confection with improved nutritional attributes
DE102004062141A1 (de) 2004-12-23 2006-07-06 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Verfahren zur Herstellung eines Rohöls aus Gemischen von Mikroorganismen und Pflanzen, das so hergestellte Öl sowie die spezifischen Verwendungen des so hergestellten und gegebenenfalls zusätzlich raffinierten Öls
DE102005003624A1 (de) 2005-01-26 2006-07-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Herstellung und Anwendung eines antioxidativ wirksamen Extraktes aus Crypthecodinium sp.
NZ563125A (en) 2005-06-03 2009-11-27 Mcfarlane Marketing Aust Pty L Lipid extract of mussels and method for preparation thereof
ES2729976T3 (es) 2005-06-07 2019-11-07 Dsm Nutritional Products Ag Microorganismos eucariotas para la producción de lípidos y antioxidantes
MX300085B (es) 2005-07-01 2012-06-08 Martek Biosciences Corp Producto oleoso que contiene acido graso poli-insaturado y usos y produccion del mismo.
US7527734B1 (en) 2005-11-15 2009-05-05 Shepherd Samuel L Rapid non-equilibrium decompression of microorganism-containing waste streams
US20090221705A1 (en) 2006-02-07 2009-09-03 Pal Rongved Omega 3
EP2044208A4 (en) 2006-07-05 2012-02-22 Photonz Corp Ltd PRODUCTION OF EPA AND ULTRA PURE POLAR LIPIDS FROM A BROADLY HETERATROPHE CULTURE
EP1887011A1 (en) 2006-08-09 2008-02-13 Thermphos Trading GmbH Alpha amino acid phosphonic acid compounds, method of preparation and use thereof
US8367395B2 (en) 2006-09-28 2013-02-05 Dsm Ip Assets B.V. Production of sterols in oleaginous yeast and fungi
US20080083352A1 (en) 2006-10-10 2008-04-10 Ernest Peter Tovani Vehicle Table System
KR100810314B1 (ko) 2006-10-11 2008-03-04 삼성전자주식회사 휴대 단말기의 키 입력 장치
US8088614B2 (en) 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
MX2009005723A (es) 2006-12-01 2009-09-28 Univ North Carolina State Proceso para la conversion de biomasa a co mbustible.
US20100227042A1 (en) 2006-12-22 2010-09-09 Christopher Penet Enzyme-Assisted De-Emulsification of Aqueous Lipid Extracts
CA2702247A1 (en) 2007-06-14 2008-12-18 Nickolaos Mitropoulos Algae growth for biofuels
US20100226977A1 (en) 2007-08-29 2010-09-09 Aker Biomarine Asa Low viscosity phospholipid compositions
CN101874117A (zh) 2007-09-12 2010-10-27 马太克生物科学公司 生物油及其制备与应用
JP4594998B2 (ja) * 2008-05-21 2010-12-08 株式会社日立製作所 エレベーターかごの速度検出装置の検査方法。
ITMI20081203A1 (it) 2008-06-30 2010-01-01 Eni Spa Procedimento per l'estrazione di acidi grassi da biomassa algale
EP2145942A1 (de) 2008-07-15 2010-01-20 Lonza Ltd. Verfahren zur Isolierung von Ölen aus Zellen und Biomasse
WO2010017243A1 (en) 2008-08-04 2010-02-11 Kai Bioenergy Continuous cultivation, harvesting, and oil extraction of photosynthetic cultures
EP3196313B1 (en) 2008-10-02 2021-03-03 Nieves Gonzalez Ramon Microalgae extract containing omega3-polyunsaturated fatty acids and method for extracting oil from micro-organisms
BRPI0920280B8 (pt) 2008-10-14 2022-11-16 Corbion Biotech Inc Composição alimentícia, e, método para fabricar uma composição alimentícia
SE534278C2 (sv) 2009-02-17 2011-06-28 Alfa Laval Corp Ab Ett kontinuerligt förfarande för isolering av oljor från alger eller mikroorganismer
US9296985B2 (en) 2009-03-10 2016-03-29 Valicor, Inc. Algae biomass fractionation
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8476060B2 (en) 2009-04-13 2013-07-02 Board Of Regents, The University Of Texas System Process for separating lipids from a biomass
WO2010138620A1 (en) 2009-05-26 2010-12-02 Solazyme, Inc. Fractionation of oil-bearing microbial biomass
KR101659765B1 (ko) 2009-09-28 2016-09-27 삼성전자주식회사 다중 모드 휴대용 단말기에서 전력 소모를 줄이기 위한 장치 및 방법
WO2011130576A1 (en) 2010-04-14 2011-10-20 Solazyme, Inc. Oleaginous yeast food compositions
EP2576801B1 (en) 2010-06-01 2019-10-02 DSM IP Assets B.V. Extraction of lipid from cells and products therefrom
SG185578A1 (en) 2010-06-14 2013-01-30 Io Mega Holding Corp Methods for the production of algae derived oils
BR112013002003A2 (pt) 2010-07-26 2019-09-24 Sapphire Energy Inc processo para recuperação de compostos oleaginosos de biomassa
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
EP2600957A4 (en) 2010-08-06 2017-11-08 ICM, Inc. Bio-oil recovery systems and methods
US20120040428A1 (en) 2010-08-13 2012-02-16 Paul Reep Procedure for extracting of lipids from algae without cell sacrifice
US20120129244A1 (en) 2010-10-17 2012-05-24 Michael Phillip Green Systems, methods and apparatuses for dewatering, flocculating and harvesting algae cells
CN101985637B (zh) 2010-11-02 2014-05-07 嘉必优生物工程（武汉）有限公司 一种微生物油脂的提取方法
EP2450425B1 (en) 2010-11-08 2014-05-14 Neste Oil Oyj A method for lipid extraction from biomass
WO2012109642A1 (en) 2011-02-12 2012-08-16 Phycal, Inc. Aqueous extraction methods for high lipid microorganisms
CN103649313B (zh) 2011-03-07 2017-10-24 Dsm营养产品股份公司 工程化破囊壶菌属微生物
WO2012125611A2 (en) 2011-03-15 2012-09-20 Iowa State University Research Foundation Oil extraction from microalgae
FR2975705B1 (fr) 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
CN102433215A (zh) 2011-09-22 2012-05-02 厦门汇盛生物有限公司 一种从真菌或藻类中物理破壁提取油脂的方法
CN102388988B (zh) 2011-11-08 2013-01-23 中国农业科学院油料作物研究所 一种微生物油的分提方法
WO2013075116A2 (en) 2011-11-17 2013-05-23 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
WO2013156720A2 (fr) 2012-04-16 2013-10-24 Roquette Freres Procédé de raffinage du squalène produit par microalgues
WO2014004999A1 (en) 2012-06-29 2014-01-03 BP Biofuels UK Limited Process for separation of renewable materials from microorganisms
AR098895A1 (es) 2013-12-20 2016-06-22 Dsm Ip Assets Bv Proceso para obtener aceite microbiano a partir de células microbianas
SG11201605066WA (en) 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
TWI708836B (zh) 2013-12-20 2020-11-01 荷蘭商Ｄｓｍ智慧財產有限公司 用於從微生物細胞獲得微生物油之方法（二）
US11001782B2 (en) 2013-12-20 2021-05-11 Dsm Nutritional Products Ag Methods of recovering oil from microorganisms
PL3082793T3 (pl) 2013-12-20 2020-10-05 Dsm Ip Assets B.V. Sposoby otrzymywania oleju drobnoustrojowego z komórek drobnoustrojowych
CN105849242A (zh) 2013-12-20 2016-08-10 玛拉可再生能源公司 从微生物中回收油的方法
SG10201911379QA (en) 2013-12-20 2020-01-30 Dsm Ip Assets Bv Process for extracting lipids for use in production of biofuels
JP2017504318A (ja) 2013-12-20 2017-02-09 ディーエスエム アイピー アセッツ ビー．ブイ． 微生物細胞から微生物油を入手するための方法
EP4303288A3 (en) 2014-07-07 2024-03-06 Nuseed Global Innovation Ltd Processes for producing industrial products from plant lipids

Also Published As

Publication number Publication date
KR20100051131A (ko) 2010-05-14
JP2013099365A (ja) 2013-05-23
US7351558B2 (en) 2008-04-01
AU2005202980C1 (en) 2009-04-02
EP1252324A4 (en) 2005-02-09
AU2005202980B2 (en) 2008-07-10
AU2012200890B2 (en) 2014-07-31
CZ303446B6 (cs) 2012-09-19
PL356587A1 (en) 2004-06-28
EP2295594A1 (en) 2011-03-16
AU2005202980A1 (en) 2005-08-04
WO2001053512A1 (en) 2001-07-26
MX275361B (en) 2010-04-21
US20190256797A1 (en) 2019-08-22
AU2016203318A1 (en) 2016-06-09
CA2397655C (en) 2012-06-05
IL150772A (en) 2010-06-16
KR20110000592A (ko) 2011-01-03
MXPA02007092A (es) 2003-02-24
MX350779B (es) 2017-09-18
KR101429236B1 (ko) 2014-08-12
EP2295594B1 (en) 2018-04-04
IL201756A (en) 2011-06-30
US20020001833A1 (en) 2002-01-03
KR20150020609A (ko) 2015-02-26
US7662598B2 (en) 2010-02-16
RU2336307C2 (ru) 2008-10-20
NO20023449L (no) 2002-09-17
CN1416469A (zh) 2003-05-07
IL206960A0 (en) 2010-12-30
JP2015133969A (ja) 2015-07-27
HUP0300556A3 (en) 2010-03-29
US20080044875A1 (en) 2008-02-21
KR101180462B1 (ko) 2012-09-06
CN100460513C (zh) 2009-02-11
KR20080007279A (ko) 2008-01-17
US7781193B2 (en) 2010-08-24
JP5722536B2 (ja) 2015-05-20
US9738851B2 (en) 2017-08-22
ES2352001T3 (es) 2011-02-14
US20080044876A1 (en) 2008-02-21
JP2010051328A (ja) 2010-03-11
NO20023449D0 (no) 2002-07-18
AU2012200890A1 (en) 2012-03-08
MX232239B (es) 2005-11-18
US20080038800A1 (en) 2008-02-14
EP2295595B1 (en) 2019-05-01
PT1252324E (pt) 2010-12-16
DE60143287D1 (de) 2010-12-02
JP5756137B2 (ja) 2015-07-29
CN101463371A (zh) 2009-06-24
CA2772540A1 (en) 2001-07-26
AU2019226124A1 (en) 2019-09-26
AU2014203384A1 (en) 2014-07-10
AU2963601A (en) 2001-07-31
JP2005278650A (ja) 2005-10-13
KR20140079870A (ko) 2014-06-27
KR100995575B1 (ko) 2010-11-19
US20140212936A1 (en) 2014-07-31
EP1252324B1 (en) 2010-10-20
AU2014203384B2 (en) 2016-03-03
NO20110858L (no) 2002-09-17
ATE485385T1 (de) 2010-11-15
AU2018200956A1 (en) 2018-03-01
RU2002119551A (ru) 2004-02-20
HK1050716A1 (en) 2003-07-04
JP2003520046A (ja) 2003-07-02
EP2302065A1 (en) 2011-03-30
US20170298288A1 (en) 2017-10-19
IL150772A0 (en) 2003-02-12
ZA200205790B (en) 2003-07-28
US6750048B2 (en) 2004-06-15
HUP0300556A2 (hu) 2003-06-28
KR101591834B1 (ko) 2016-02-18
KR20030013367A (ko) 2003-02-14
ES2735987T3 (es) 2019-12-23
MX297659B (en) 2012-03-29
EP1252324A1 (en) 2002-10-30
CA2397655A1 (en) 2001-07-26
US20040229325A1 (en) 2004-11-18
IL206961A (en) 2011-11-30
US10329515B2 (en) 2019-06-25
KR20120070588A (ko) 2012-06-29
KR20130032395A (ko) 2013-04-01
EP2295595A1 (en) 2011-03-16
KR101429238B1 (ko) 2014-08-12
BR0107699B1 (pt) 2014-05-27
NZ520287A (en) 2004-01-30
DK1252324T3 (da) 2010-12-20
ES2675517T3 (es) 2018-07-11
AU780619B2 (en) 2005-04-07
JP4020642B2 (ja) 2007-12-12
JP4537887B2 (ja) 2010-09-08

Similar Documents

Publication Publication Date Title
BR0107699A (pt) Processo de extração sem o uso de solventes e lipìdeos obtidos
BR0107832A (pt) Processo de extração sem o uso de solvente e lipìdios obtidos
BRPI0410680A (pt) processo para a recuperação de 1,3-propanodiol de um caldo de fermentação
CO5630034A1 (es) Metodo para producir esteres de alquilo
BR0313251A (pt) Métodos de extração de polìmero
Rodríguez-López et al. Extraction, separation and characterization of lipopeptides and phospholipids from corn steep water
PT1246633E (pt) Processo de extraccao dos insaponificaveis dos oleos vegetais por meio de cloro-1-butano
PE6297A1 (es) Un metodo de identificar un producto de petroleo que contiene un marcador de base reactiva
BR0101228A (pt) Ormoceres, processo para a sua preparação, assimcomo aplicação
ES2157166B1 (es) Procedimiento para la obtencion de licopeno.
IL194315A (en) A process for isolating and stabilizing low molecular weight aminoglycans from eggshell debris
EP1894973A4 (en) PROCESS FOR PRODUCING A PVP-FULLERENE COMPLEX AND AQUEOUS SOLUTION OF THIS COMPLEX
EP1424341A3 (en) Production method for purine nucleotide derivative disodium crystals and alcohol removing method
BR9808011A (pt) Processo para a purificação de caprolactama
KR960034173A (ko) 2,2,6,6-테트라메틸피페리딘-4-온의 메틸화 방법
BR0112064A (pt) Processo para a preparação de derivados da quinolina
AR046701A1 (es) Procedimiento para el tratamiento de residuos pesados que contienen sodio y combustible obtenido de este modo
BRPI0518808A2 (pt) composto hidroxi-aromÁtico, processo para sua preparaÇço, e uso do composto
BR0309622A (pt) Composições aquosas lìquidas de derivados de ciclodextrina reativos e um processo de acabamento que usa a referida composição
PE20100240A1 (es) Metodo para producir una composicion que comprende la epotilona (1s, 3s, 7s, 10r,11s,12s,16r)7, 11hidroxi-3-(2-metil-benzotiazol-5-il)-10-(prop-2-1-il)-8,8-12,16-tetrametil-4,17dioxabiciclo[14.1.0]heptade can-5,9-diona
BRPI0506222A (pt) aperfeiçoamento em processo de produção de caulim grosseiro com elevada alvura e baixa viscosidade para a utilização como revestimento
TW200602497A (en) Solventless extraction process
DE69912824T2 (de) Papierprodukte und verfahren zu deren herstellung
BR0215504A (pt) Processo para a produção de açúcares de soja e o produto produzido a partir do mesmo
BR102023006427A8 (pt) Processo para produzir um produto de proteína

Legal Events

Date Code Title Description
B25F Entry of change of name and/or headquarter and transfer of application, patent and certif. of addition of invention: change of name on requirement

Owner name: OMEGATECH, INC. (US)

Free format text: A FIM DE ATENDER A ALTERACAO DE NOME REQUERIDA NA PETICAO NO 066989/RJ DE 03/12/2003, FAVOR REAPRESENTAR DOCUMENTO DE ALTERACAO DE NOME COM A DEVIDA LEGALIZACAO CONSULAR.

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: OMEGATECH, INC. (US)

Free format text: REFERENTE A RPI 1854 COD. (25.6) DE 18/07/2006, POR TER SIDO INDEVIDO.

B25D Requested change of name of applicant approved

Owner name: MARTEK BIOSCIENCES BOULDER CORPORATION (US)

Free format text: ALTERADO DE: OMEGATECH, INC.

B25A Requested transfer of rights approved

Owner name: MARTEK BIOSCIENCES CORPORATION (US)

Free format text: TRANSFERIDO DE: MARTEK BIOSCIENCES BOULDER CORPORATION

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B25A Requested transfer of rights approved

Owner name: DSM IP ASSETS B.V. (NL)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/05/2014, OBSERVADAS AS CONDICOES LEGAIS.