BG20596A3 - Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазини - Google Patents
Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазиниInfo
- Publication number
- BG20596A3 BG20596A3 BG026972A BG2697273A BG20596A3 BG 20596 A3 BG20596 A3 BG 20596A3 BG 026972 A BG026972 A BG 026972A BG 2697273 A BG2697273 A BG 2697273A BG 20596 A3 BG20596 A3 BG 20596A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- piperazines
- benzhydryl
- hydroxybenzyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2226767A DE2226767A1 (de) | 1972-06-02 | 1972-06-02 | N-benzhydryl-n'-p-hydroxybenzylpiperazin und verfahren zu seiner herstellung |
| DE19732312212 DE2312212A1 (de) | 1973-03-12 | 1973-03-12 | N-(p-chlorbenzhydryl)-n'-p-hydroxybenzyl-piperazin und verfahren zu seiner herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG20596A3 true BG20596A3 (bg) | 1975-12-05 |
Family
ID=25763357
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG023741A BG20595A3 (bg) | 1972-06-02 | 1973-05-29 | Методл за получаване на n-бензхидрил n-р-хидроксилбензил-пиперазини |
| BG026973A BG20371A3 (bg) | 1972-06-02 | 1973-05-29 | Метод за получаване на n-бензхидрил-n'-р- хидробензил-пиперазини |
| BG026972A BG20596A3 (bg) | 1972-06-02 | 1973-05-29 | Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазини |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG023741A BG20595A3 (bg) | 1972-06-02 | 1973-05-29 | Методл за получаване на n-бензхидрил n-р-хидроксилбензил-пиперазини |
| BG026973A BG20371A3 (bg) | 1972-06-02 | 1973-05-29 | Метод за получаване на n-бензхидрил-n'-р- хидробензил-пиперазини |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US3868377A (bg) |
| JP (1) | JPS4948687A (bg) |
| AR (5) | AR196936A1 (bg) |
| AT (3) | AT331802B (bg) |
| AU (1) | AU470393B2 (bg) |
| BG (3) | BG20595A3 (bg) |
| CA (1) | CA980347A (bg) |
| CH (4) | CH579064A5 (bg) |
| CS (4) | CS182234B2 (bg) |
| DD (1) | DD106644A5 (bg) |
| DK (1) | DK139751C (bg) |
| EG (1) | EG11434A (bg) |
| ES (3) | ES415465A1 (bg) |
| FI (1) | FI55656C (bg) |
| FR (1) | FR2186265B1 (bg) |
| GB (1) | GB1386916A (bg) |
| HU (1) | HU165312B (bg) |
| IE (1) | IE37717B1 (bg) |
| IL (1) | IL42384A (bg) |
| NL (1) | NL7306771A (bg) |
| NO (1) | NO138026C (bg) |
| PH (1) | PH9485A (bg) |
| PL (3) | PL91050B1 (bg) |
| RO (3) | RO68378A (bg) |
| SE (1) | SE396385B (bg) |
| SU (4) | SU507238A3 (bg) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59101475A (ja) * | 1982-12-02 | 1984-06-12 | Nippon Chemiphar Co Ltd | 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤 |
| HU186656B (en) * | 1982-12-28 | 1985-09-30 | Richter Gedeon Vegyeszet | Process for producing new benzhydryl-piperazine derivatives, acid additionak salts and pharmaceutical compositions containing them |
| GB8320701D0 (en) * | 1983-08-01 | 1983-09-01 | Wellcome Found | Chemotherapeutic agent |
| JPS60222472A (ja) * | 1984-03-30 | 1985-11-07 | Kanebo Ltd | 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物 |
| DE68916126T2 (de) * | 1988-08-05 | 1994-10-27 | Nippon Chemiphar Co | Optisch aktive Piperazin-Derivate. |
| FR2661176B1 (fr) * | 1990-04-20 | 1992-06-12 | Adir | Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive. |
| EP0682664B1 (en) * | 1993-12-08 | 2001-03-14 | Alcon Laboratories, Inc. | Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents |
| WO2009147389A2 (en) * | 2008-06-02 | 2009-12-10 | Cipla Limited | Processes for the synthesis of levocetirizine and intermediates for use therein |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2709169A (en) * | 1955-05-24 | X c chs | ||
| US3051710A (en) * | 1959-12-21 | 1962-08-28 | Lakeside Lab Inc | Glycolic acid amide derivatives of piperazine and use thereof |
-
1973
- 1973-05-15 NL NL7306771A patent/NL7306771A/xx not_active Application Discontinuation
- 1973-05-28 IE IE855/73A patent/IE37717B1/xx unknown
- 1973-05-29 RO RO7382539A patent/RO68378A/ro unknown
- 1973-05-29 BG BG023741A patent/BG20595A3/bg unknown
- 1973-05-29 BG BG026973A patent/BG20371A3/bg unknown
- 1973-05-29 CS CS7300003883A patent/CS182234B2/cs unknown
- 1973-05-29 CS CS3878A patent/CS178430B2/cs unknown
- 1973-05-29 RO RO7374944A patent/RO62900A/ro unknown
- 1973-05-29 RO RO7382540A patent/RO68379A/ro unknown
- 1973-05-29 CS CS7600004284A patent/CS182248B2/cs unknown
- 1973-05-29 US US364764A patent/US3868377A/en not_active Expired - Lifetime
- 1973-05-29 CS CS3877A patent/CS178429B2/cs unknown
- 1973-05-29 BG BG026972A patent/BG20596A3/bg unknown
- 1973-05-29 IL IL42384A patent/IL42384A/en unknown
- 1973-05-30 SE SE7307692A patent/SE396385B/xx unknown
- 1973-05-30 GB GB2571073A patent/GB1386916A/en not_active Expired
- 1973-05-31 AR AR248325A patent/AR196936A1/es active
- 1973-05-31 PL PL1973162986A patent/PL91050B1/pl unknown
- 1973-05-31 PL PL1973186639A patent/PL94759B1/pl unknown
- 1973-05-31 DD DD171224A patent/DD106644A5/xx unknown
- 1973-05-31 AR AR248326A patent/AR194688A1/es active
- 1973-05-31 AU AU56343/73A patent/AU470393B2/en not_active Expired
- 1973-05-31 SU SU1926939A patent/SU507238A3/ru active
- 1973-05-31 JP JP48060375A patent/JPS4948687A/ja active Pending
- 1973-05-31 CA CA172,824A patent/CA980347A/en not_active Expired
- 1973-05-31 SU SU1926942A patent/SU530644A3/ru active
- 1973-05-31 EG EG206/73A patent/EG11434A/xx active
- 1973-05-31 PL PL1973186638A patent/PL97129B1/pl unknown
- 1973-05-31 SU SU1926943A patent/SU508196A3/ru active
- 1973-05-31 AR AR248327A patent/AR201001A1/es active
- 1973-05-31 HU HUCA347A patent/HU165312B/hu unknown
- 1973-05-31 PH PH14678*UA patent/PH9485A/en unknown
- 1973-06-01 FI FI1797/73A patent/FI55656C/fi active
- 1973-06-01 AT AT483173A patent/AT331802B/de not_active IP Right Cessation
- 1973-06-01 NO NO2303/73A patent/NO138026C/no unknown
- 1973-06-01 AT AT483273A patent/AT331252B/de not_active IP Right Cessation
- 1973-06-01 ES ES73415465A patent/ES415465A1/es not_active Expired
- 1973-06-01 AT AT483073A patent/AT331801B/de not_active IP Right Cessation
- 1973-06-01 FR FR7319998A patent/FR2186265B1/fr not_active Expired
- 1973-06-01 DK DK304673A patent/DK139751C/da active
- 1973-06-01 ES ES415464A patent/ES415464A1/es not_active Expired
- 1973-06-01 ES ES415466A patent/ES415466A1/es not_active Expired
- 1973-06-04 CH CH802973A patent/CH579064A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH802873A patent/CH574949A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH803073A patent/CH593959A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH1193576A patent/CH594651A5/xx not_active IP Right Cessation
-
1974
- 1974-01-01 AR AR252417A patent/AR204987A1/es active
- 1974-02-18 AR AR252416A patent/AR200764A1/es active
- 1974-12-13 SU SU7402082532A patent/SU577995A3/ru active
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