Nothing Special   »   [go: up one dir, main page]

ATE419832T1 - Stabile arzneimittellösung für druckdosierinhalatoren - Google Patents

Stabile arzneimittellösung für druckdosierinhalatoren

Info

Publication number
ATE419832T1
ATE419832T1 AT01112230T AT01112230T ATE419832T1 AT E419832 T1 ATE419832 T1 AT E419832T1 AT 01112230 T AT01112230 T AT 01112230T AT 01112230 T AT01112230 T AT 01112230T AT E419832 T1 ATE419832 T1 AT E419832T1
Authority
AT
Austria
Prior art keywords
pressure
medicinal solution
stable medicinal
dosage inhalers
inhalers
Prior art date
Application number
AT01112230T
Other languages
English (en)
Inventor
David Lewis
David Ganderton
Brian Meakin
Gaetano Brambilla
Alessandra Ferraris
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8163952&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE419832(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE419832T1 publication Critical patent/ATE419832T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01112230T 2000-05-22 2001-05-18 Stabile arzneimittellösung für druckdosierinhalatoren ATE419832T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2000/004635 WO2001089480A1 (en) 2000-05-22 2000-05-22 Stable pharmaceutical solution formulations for pressurised metered dose inhalers

Publications (1)

Publication Number Publication Date
ATE419832T1 true ATE419832T1 (de) 2009-01-15

Family

ID=8163952

Family Applications (4)

Application Number Title Priority Date Filing Date
AT10166800T ATE541563T1 (de) 2000-05-22 2001-05-18 Stabile arzneimittellösung für druckdosierinhalatoren
AT01112230T ATE419832T1 (de) 2000-05-22 2001-05-18 Stabile arzneimittellösung für druckdosierinhalatoren
AT04011423T ATE415945T1 (de) 2000-05-22 2001-05-18 Stabile arzneimittellösung für druckdosierinhalatoren
AT07004772T ATE502624T1 (de) 2000-05-22 2001-05-18 Stabile pharmazeutische lösungsformulierungen für unter druck stehende inhaliergeräte für die verabreichung abgemessener dosen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT10166800T ATE541563T1 (de) 2000-05-22 2001-05-18 Stabile arzneimittellösung für druckdosierinhalatoren

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT04011423T ATE415945T1 (de) 2000-05-22 2001-05-18 Stabile arzneimittellösung für druckdosierinhalatoren
AT07004772T ATE502624T1 (de) 2000-05-22 2001-05-18 Stabile pharmazeutische lösungsformulierungen für unter druck stehende inhaliergeräte für die verabreichung abgemessener dosen

Country Status (41)

Country Link
US (3) US6716414B2 (de)
EP (4) EP2223682B1 (de)
JP (1) JP5392880B2 (de)
CN (1) CN1213732C (de)
AR (1) AR029523A1 (de)
AT (4) ATE541563T1 (de)
AU (2) AU5070100A (de)
BE (1) BE2011C032I2 (de)
BG (1) BG65883B1 (de)
BR (1) BR0015884A (de)
CA (1) CA2411047C (de)
CY (6) CY1108833T1 (de)
CZ (1) CZ303833B6 (de)
DE (5) DE60137282D1 (de)
DK (4) DK1466594T3 (de)
DZ (1) DZ3358A1 (de)
EA (1) EA005179B1 (de)
EE (1) EE05167B1 (de)
ES (4) ES2320194T3 (de)
FR (1) FR11C0041I2 (de)
HK (1) HK1058900A1 (de)
HR (1) HRP20021025B1 (de)
HU (2) HU230804B1 (de)
IL (2) IL152955A0 (de)
JO (1) JO2310B1 (de)
LT (1) LTC1787639I2 (de)
LU (1) LU91875I2 (de)
ME (2) ME00220B (de)
MX (1) MXPA02011414A (de)
MY (2) MY143733A (de)
NL (1) NL300393I2 (de)
NO (3) NO342935B1 (de)
PE (1) PE20011323A1 (de)
PT (4) PT1787639E (de)
SA (1) SA01220126B1 (de)
SI (4) SI2223682T1 (de)
SK (1) SK286694B6 (de)
TN (1) TNSN01074A1 (de)
TW (1) TWI284047B (de)
UA (1) UA73986C2 (de)
WO (1) WO2001089480A1 (de)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
ATE286716T1 (de) * 1999-11-23 2005-01-15 Glaxo Group Ltd Pharmazeutische formulierungen enthaltend salmeterol
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
US20060257324A1 (en) 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
BR0015884A (pt) * 2000-05-22 2003-07-08 Chiesi Farma Spa Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados
PL360283A1 (en) * 2000-05-23 2004-09-06 Glaxo Group Limited Aerosol container for formulations of salmeterol xinafoate
FI20002177A0 (fi) * 2000-10-02 2000-10-02 Orion Yhtymae Oyj Uusi yhdistelmä astman hoitoon
EP1241113A1 (de) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhalator mit Mitteln um chemische Stabilität der darin enthaltenen medizinischen Aerosollösung zu verbessern
PT1372608E (pt) * 2001-03-30 2008-01-04 Jagotec Ag Formulações de aerossol médicas
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
SI1273292T1 (en) 2001-07-02 2004-12-31 Chiesi Farmaceutici S.P.A. Optimised formulation of tobramycin for aerosolization
US7906102B2 (en) 2001-10-03 2011-03-15 Vanderbilt University Ligands to radiation-induced molecules
US7306925B2 (en) 2001-11-09 2007-12-11 Vanderbilt University Phage antibodies to radiation-inducible neoantigens
EP1415647A1 (de) * 2002-10-23 2004-05-06 CHIESI FARMACEUTICI S.p.A. Langwirkende beta-2-Agonisten in ultrafeiner Formulierung
EP1340492A1 (de) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Aerosolformulierungen zur pulmonalen Verabreichung von Arzneimitteln mit systemischer Wirkung
DK3384931T3 (da) * 2002-03-01 2019-09-16 Chiesi Farm Spa Superfin formoterolformulering
US20040166065A1 (en) 2002-08-14 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation comprising an anticholinergic
PL375511A1 (en) * 2002-08-14 2005-11-28 Boehringer Ingelheim Pharma Gmbh & Co.Kg Aerosol formulation for inhalation containing an anticholinergic agent
US7244742B2 (en) * 2002-08-17 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co Kg Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic
EP1452179A1 (de) * 2003-02-27 2004-09-01 CHIESI FARMACEUTICI S.p.A. Neue Kombination von hochwirksamer langzeitiger Beta-2-Agonist und einem Corticosteroid
US20050003024A1 (en) * 2003-03-04 2005-01-06 The Procter & Gamble Company Regulation of mammalian hair growth
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
EP1651224B1 (de) * 2003-07-31 2011-10-05 Boehringer Ingelheim International GmbH Medikamente für inhalationen enthaltend ein anticholinergikum und ein betamimetikum
JP2007501194A (ja) * 2003-08-05 2007-01-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ステロイドとβ模倣薬を含む吸入用薬剤
CA2538997A1 (en) * 2003-09-15 2005-03-24 Vectura Limited Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
GB0323684D0 (en) 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
CN100457087C (zh) * 2004-02-27 2009-02-04 奇斯药制品公司 用于加压计量吸入器的稳定的药用溶液制剂
IL177103A0 (en) * 2004-02-27 2006-12-10 Chiesi Farma Spa Stable pharmaceutical solution formulations for pressurized metered dose inhalers
EP1595531A1 (de) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stabile Arzneimittellösung für Druckdosierinhalatoren
CA2565747A1 (en) * 2004-05-13 2005-12-01 Chiesi Farmaceutici S.P.A. Medicinal aerosol formulation products with improved chemical stability
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
KR101313959B1 (ko) * 2005-02-25 2013-10-02 키에시 파르마슈티시 엣스. 피. 에이. 금속이온 봉쇄제로 구성되는 압축계량된 도스 흡입기용약제 에어로졸 조성물
JP2008534611A (ja) * 2005-03-30 2008-08-28 シェーリング コーポレイション 抗コリン作用薬、コルチコステロイドおよび長時間作用性βアゴニストを合わせる薬物および方法
DE102005055960A1 (de) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
GB0525680D0 (en) 2005-12-16 2006-01-25 Peplin Ltd Therapeutic compositions
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
GB0613761D0 (en) * 2006-07-11 2006-08-23 Norton Healthcare Ltd A pharmaceutical formulation and method for the preparation thereof
EP1982709A1 (de) 2007-04-19 2008-10-22 CHIESI FARMACEUTICI S.p.A. Verwendung einer Zusammensetzung mit Formoterol und Beclomethason-Dipropionat zur Vorbeugung oder Behandlung von akutem Asthma
US8227027B2 (en) 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
EP2077132A1 (de) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung
GB0801876D0 (en) * 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
US20090208424A1 (en) * 2008-02-19 2009-08-20 Todd Maibach Compositions and methods for delivery of solution to the skin
US20100055045A1 (en) 2008-02-26 2010-03-04 William Gerhart Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations
EP3311820A1 (de) * 2008-02-26 2018-04-25 Sunovion Respiratory Development Inc. Verfahren und system zur behandlung der chronisch obstruktiver lungenerkrankung durch verabreichung zerstäubter anticholinergika
EP2100599A1 (de) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
EP2100598A1 (de) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
EP2355808A4 (de) * 2008-10-23 2012-04-25 Sunovion Pharmaceuticals Inc Arformoterol- und tiotropium-zusammensetzungen sowie verwendungsverfahren
EP2201934A1 (de) * 2008-12-23 2010-06-30 CHIESI FARMACEUTICI S.p.A. Tiotropium-Aerosolformulierungsprodukte mit verbesserter Chemikalienbeständigkeit
WO2010112358A2 (de) 2009-03-31 2010-10-07 Boehringer Ingelheim International Gmbh Verfahren zur beschichtung einer oberfläche eines bauteils
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
WO2011038872A1 (en) * 2009-10-02 2011-04-07 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol formulations of formoterol and beclometasone dipropionate
GB0918150D0 (en) * 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
CN104225735B (zh) 2009-11-25 2018-12-07 贝林格尔.英格海姆国际有限公司 喷雾器
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2512438B1 (de) 2009-12-16 2017-01-25 3M Innovative Properties Company Formulierungen und verfahren zur steuerung der mdi-partikelgrössenfreisetzung
BR112012015334A2 (pt) 2009-12-23 2016-03-15 Chiesi Farma Spa terapia combinada para doença pulmonar obstrutiva crônica
PL2515854T3 (pl) * 2009-12-23 2014-08-29 Chiesi Farm Spa Preparat w aerozolu do stosowania w pochp
AU2010334859A1 (en) * 2009-12-23 2012-07-12 Chiesi Farmaceutici S.P.A. Combination therapy for COPD
JP5874724B2 (ja) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
WO2012010854A1 (en) 2010-07-23 2012-01-26 Cipla Limited Inhalation formulations comprising carmoterol in combination with a corticosteroid
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
EP2510928A1 (de) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013019730A1 (en) 2011-07-29 2013-02-07 The Washington University Antibodies to tip-1 and grp78
GB201200525D0 (en) 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
GB201200504D0 (en) * 2011-12-19 2012-02-22 Teva Branded Pharmaceutical Prod R & D Inc An inhaler
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP2835146B1 (de) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Zerstäuber
EP3030298B1 (de) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Vernebler
CN105848642A (zh) * 2013-12-30 2016-08-10 奇斯药制品公司 格隆溴铵和福莫特罗组合的稳定的加压气雾剂溶液组合物
DK3089735T3 (en) 2013-12-30 2018-09-17 Chiesi Farm Spa STABLE PRESSURE AEROSOL SOLUTION COMPOSITION OF GLYCOPYRRONIUM BROMIDE AND FORMOTEROL COMBINATION
EP3139984B1 (de) 2014-05-07 2021-04-28 Boehringer Ingelheim International GmbH Zerstäuber
CA2948072C (en) 2014-05-07 2023-06-27 Boehringer Ingelheim International Gmbh Nebulizer and container
DK3139979T3 (da) 2014-05-07 2023-10-09 Boehringer Ingelheim Int Enhed, forstøver og fremgangsmåde
US10034866B2 (en) 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
EP3172222A4 (de) 2014-07-24 2018-03-21 Washington University Gegen strahlungsinduzierte moleküle gerichtete zusammensetzungen und verfahren zur verwendung davon
CN104225739A (zh) * 2014-09-30 2014-12-24 四川普锐特医药科技有限责任公司 一种医用定量吸入气雾剂
EP3701940A1 (de) 2015-12-04 2020-09-02 Mexichem Fluor S.A. de C.V. Pharmazeutische zusammensetzung
US10098837B2 (en) 2016-07-28 2018-10-16 Chiesi Farmaceutici S.P.A. Combination therapy for COPD
WO2018148595A1 (en) 2017-02-10 2018-08-16 Washington University Antibodies to tip1 and methods of use thereof
EA202092976A1 (ru) 2018-06-04 2021-03-16 Люпин Инк. Устойчивые фармацевтические композиции для дозированных ингаляторов под давлением
WO2020152548A1 (en) * 2019-01-24 2020-07-30 Glenmark Pharmaceuticals Limited Stable aerosol inhalation compositions of formoterol
CN112137957B (zh) 2019-06-26 2022-07-29 长风药业股份有限公司 一种药用吸入气雾剂及其制备方法
AU2019477296A1 (en) 2019-12-02 2022-04-14 Chiesi Farmaceutici S.P.A. Stainles steel can for pressurised metered dose inhalers
KR20220133193A (ko) 2020-01-28 2022-10-04 키에시 파르마슈티시 엣스. 피. 에이. 완충된 약제학적 제제를 포함하는 가압 정량 흡입기
GB202001537D0 (en) * 2020-02-05 2020-03-18 Consort Medical Plc Pressurised dispensing container
GEP20247642B (en) 2020-02-20 2024-07-10 Chiesi Farm Spa Pressurised metered dose inhalers comprising buffered pharmaceutical formulation
US11642372B2 (en) * 2020-05-01 2023-05-09 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US11826382B2 (en) 2020-05-01 2023-11-28 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US12042514B2 (en) 2020-05-01 2024-07-23 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
MX2023001201A (es) 2020-07-31 2023-05-03 Chemo Res S L Terapia combinada para la administracion por inhalacion.
CN116419749A (zh) * 2020-10-09 2023-07-11 奇斯药制品公司 用于加压定量吸入器的药物制剂
GB2614901A (en) 2022-01-21 2023-07-26 Nanopharm Ltd Inhalable formulations
AU2023248361A1 (en) 2022-04-06 2024-10-10 Rapt Therapeutics, Inc. Chemokine receptor modulators and uses thereof
WO2023227782A1 (en) 2022-05-27 2023-11-30 Chiesi Farmaceutici S.P.A. A pharmaceutical formulation for pressurised metered dose inhaler
WO2023227783A1 (en) 2022-05-27 2023-11-30 Chiesi Farmaceutici S.P.A. A pharmaceutical formulation for pressurised metered dose inhaler

Family Cites Families (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361306A (en) 1966-03-31 1968-01-02 Merck & Co Inc Aerosol unit dispensing uniform amounts of a medically active ingredient
US3622053A (en) 1969-12-10 1971-11-23 Schering Corp Aerosol inhaler with flip-up nozzle
MX3864E (es) 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
US4185100A (en) 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US4499108A (en) * 1983-06-08 1985-02-12 Schering Corporation Stable pleasant-tasting albuterol sulfate pharmaceutical formulations
GB8334494D0 (en) * 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
IT1196142B (it) 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
US5192528A (en) 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
IL97065A (en) 1990-02-02 1994-01-25 Fisons Plc Repellent preparations for aerosol
CA2098298A1 (en) 1990-12-19 1992-06-20 Susan M. Milosovich Aerosol formulations
US6006745A (en) * 1990-12-21 1999-12-28 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
EP0504112A3 (en) 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
US5874063A (en) * 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
HU214476B (hu) 1991-05-21 1998-03-30 Abbott Laboratories Aerosol inhaláló eszköz
WO1993004718A1 (de) 1991-08-29 1993-03-18 Sroka, Peter-Christian Medizinisches gerät zur inhalation von dosier-aerosolen
NZ244439A (en) 1991-09-25 1994-01-26 Fisons Plc Pressurised aerosol compositions comprising hydrofluoroalkane, dispersed
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
JP3908269B2 (ja) 1991-12-18 2007-04-25 スリーエム カンパニー 懸濁エアゾール製剤
DE4230876A1 (de) 1992-03-17 1993-09-23 Asta Medica Ag Druckgaspackungen unter verwendung von polyoxyethylen-glyceryl-oleaten
GB2288978B (en) 1992-12-09 1997-04-09 Boehringer Ingelheim Pharma Hydrocarbon inhalant solutions stabilised by organic or inorganic acids
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
WO1994014490A1 (de) 1992-12-23 1994-07-07 Bernhard Hugemann Verfestigter arzneistoffvorrat für die mechanische erzeugung inhalierbarer wirkstoffpartikel
JP3987963B2 (ja) * 1993-03-17 2007-10-10 スリーエム カンパニー エステルー，アミド−又はメルカプトエステル−誘導分散促進剤を含むエーロゾル配合物
EP0689423B1 (de) 1993-03-17 1997-09-17 Minnesota Mining And Manufacturing Company Aerosolzubereitung, enthaltend ein aus einem diol-disäure-derivat abgeleitetes dispergiermittel
US6596260B1 (en) 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
AU680967B2 (en) 1993-12-20 1997-08-14 Minnesota Mining And Manufacturing Company Flunisolide aerosol formulations
GB9425160D0 (en) * 1994-12-10 1995-02-08 Glaxo Group Ltd Medicaments
IL116460A (en) * 1994-12-22 2003-10-31 Astra Ab Aerosol drug formulations for inhalation and method for their preparation
GB9426252D0 (en) * 1994-12-24 1995-02-22 Glaxo Group Ltd Pharmaceutical composition
DE4446891A1 (de) 1994-12-27 1996-07-04 Falk Pharma Gmbh Stabile wäßrige Budesonid-Lösung
US5653961A (en) * 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
CN1217654C (zh) 1995-04-14 2005-09-07 史密丝克莱恩比彻姆公司 舒喘宁的计定剂量吸入器
JP3573213B2 (ja) * 1995-04-14 2004-10-06 グラクソ、ウェルカム、インコーポレーテッド ベクロメタゾンジプロピオネート用計量投与用吸入器
CN1113675C (zh) 1995-04-14 2003-07-09 葛兰素惠尔康公司 丙酸福地卡松的计定剂量吸入器
SK284447B6 (sk) 1995-04-14 2005-04-01 Glaxo Wellcome Inc. Merací dávkovací inhalátor
US6135628A (en) * 1995-10-13 2000-10-24 Boehringer Ingelheim Pharmceuticals, Inc. Method and apparatus for homogenizing aerosol formulations
GB9612297D0 (en) 1996-06-11 1996-08-14 Minnesota Mining & Mfg Medicinal aerosol formulations
AU3453897A (en) 1996-07-08 1998-02-02 Rhone-Poulenc Rorer Limited Medicinal cyclosporin-a aerosol solution formulation
WO1998003533A1 (en) 1996-07-24 1998-01-29 Oligos Etc. And Oligos Therapeutics, Inc. Antisense oligonucleotides as antibacterial agents
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
GB9620187D0 (en) 1996-09-27 1996-11-13 Minnesota Mining & Mfg Medicinal aerosol formulations
ES2244008T3 (es) * 1996-12-04 2005-12-01 Link Products Limited Composiciones farmaceuticas y dispositivos para su administracion.
US6413496B1 (en) 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
JP2001511160A (ja) * 1997-02-05 2001-08-07 ヤゴ リサーチ アクチェンゲゼルシャフト 医学用エアゾール配合物
US6126919A (en) * 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US5891419A (en) 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe flunisolide aerosol formulations for oral inhalation
US6000537A (en) * 1997-06-10 1999-12-14 U.S. Philips Corporation Housing with readable side walls for a disc-shaped information carrier
GB2326334A (en) * 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US6324827B1 (en) * 1997-07-01 2001-12-04 Bp Corporation North America Inc. Method of generating power in a dry low NOx combustion system
BR7702049U (pt) 1997-09-05 1999-09-14 Chiesi Farma Spa Bico pulverizador para utilização em inalador oral para medicamentos aerossóis
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
WO1999036095A1 (en) * 1998-01-13 1999-07-22 Astrazeneca Uk Limited PHARMACEUTICAL COMPOSITIONS COMPRISING A COMPOUND HAVING DOPAMINE (D2) RECEPTOR AGONIST ACTIVITY AND A COMPOUND (B) HAVING β2-ADRENORECEPTOR AGONIST ACTIVITY
US6045784A (en) 1998-05-07 2000-04-04 The Procter & Gamble Company Aerosol package compositions containing fluorinated hydrocarbon propellants
SE9802073D0 (sv) 1998-06-11 1998-06-11 Astra Ab New use
ATE253896T1 (de) * 1998-06-18 2003-11-15 Boehringer Ingelheim Pharma Zwei oder mehrere wirkstoffe enthaltende pharmazeutische aerosolformulierungen
US6451285B2 (en) * 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
US6241969B1 (en) 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
WO2000006121A1 (de) 1998-07-24 2000-02-10 Jago Research Ag Medizinische aerosolformulierungen
WO2000007567A1 (de) * 1998-08-04 2000-02-17 Jago Research Ag Medizinische aerosolformulierungen
US6136294C1 (en) * 1998-09-22 2002-09-24 Aeropharm Technology Inc Amino acid stabilized medical aerosol formulation
DE19847969A1 (de) 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Lagerfähig flüssige Formulierung mit Formoterol
JP3636430B2 (ja) * 1998-10-17 2005-04-06 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト フォルモテロールを含む貯蔵可能な活性物質濃縮物
ATE382386T1 (de) * 1998-11-13 2008-01-15 Jagotec Ag Multidosis-trockenpulverinhalator mit pulverreservoir
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
US6290930B1 (en) 1998-12-18 2001-09-18 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
GB9902689D0 (en) * 1999-02-08 1999-03-31 Novartis Ag Organic compounds
DK1158958T3 (da) 1999-03-05 2007-10-08 Chiesi Farma Spa Forbedret pulverformulering til inhalering
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
JP2003518484A (ja) 1999-12-24 2003-06-10 グラクソ グループ リミテッド サルメテロールおよびプロピオン酸フルチカゾンの医薬用エアゾル製剤
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
BR0015884A (pt) 2000-05-22 2003-07-08 Chiesi Farma Spa Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados
DK3384931T3 (da) * 2002-03-01 2019-09-16 Chiesi Farm Spa Superfin formoterolformulering
EP1340492A1 (de) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Aerosolformulierungen zur pulmonalen Verabreichung von Arzneimitteln mit systemischer Wirkung
EP1595531A1 (de) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stabile Arzneimittellösung für Druckdosierinhalatoren

Also Published As

Publication number Publication date
CY2009009I1 (el) 2014-04-09
HUP0302007A2 (hu) 2003-09-29
DK1787639T3 (da) 2011-05-09
CY1108833T1 (el) 2014-07-02
BG65883B1 (bg) 2010-04-30
EP1157689B1 (de) 2009-01-07
EA200201058A1 (ru) 2003-04-24
EA005179B1 (ru) 2004-12-30
CN1452479A (zh) 2003-10-29
PT1157689E (pt) 2009-03-23
NL300393I1 (en) 2009-09-01
SK16522002A3 (sk) 2003-04-01
EP1787639A2 (de) 2007-05-23
PT1466594E (pt) 2009-02-13
US20060083693A1 (en) 2006-04-20
EP2223682B1 (de) 2012-01-18
EP1466594A3 (de) 2004-12-01
US20040047809A1 (en) 2004-03-11
DE60136864D1 (de) 2009-01-15
HK1058900A1 (en) 2004-06-11
NO342935B1 (no) 2018-09-03
DE60137282D1 (de) 2009-02-26
ATE502624T1 (de) 2011-04-15
LU91875I2 (fr) 2011-11-21
ME00220B (me) 2010-10-10
CY1108968T1 (el) 2014-04-09
EP2223682A1 (de) 2010-09-01
BE2011C032I2 (de) 2020-08-20
CY1113028T1 (el) 2016-04-13
PL359149A1 (en) 2004-08-23
EE05167B1 (et) 2009-06-15
CY2011014I1 (el) 2015-10-07
UA73986C2 (uk) 2005-10-17
HU230804B1 (hu) 2018-06-28
MXPA02011414A (es) 2003-06-06
TWI284047B (en) 2007-07-21
DE122009000035I1 (de) 2009-11-05
EP1157689A1 (de) 2001-11-28
EE200200649A (et) 2004-06-15
HUP0302007A3 (en) 2006-07-28
FR11C0041I2 (fr) 2015-09-04
DK2223682T3 (da) 2012-03-19
HUS1800032I1 (hu) 2018-08-28
MY127145A (en) 2006-11-30
NO20025568L (no) 2002-11-20
NO2019003I1 (no) 2019-01-16
DK1157689T3 (da) 2009-03-16
PT1787639E (pt) 2011-06-08
DK1466594T3 (da) 2009-03-02
LTC1787639I2 (lt) 2021-05-25
AR029523A1 (es) 2003-07-02
IL152955A0 (en) 2003-06-24
EP1466594A2 (de) 2004-10-13
JO2310B1 (en) 2005-09-12
LTPA2011011I1 (lt) 2019-08-26
NO20025568D0 (no) 2002-11-20
BR0015884A (pt) 2003-07-08
PT2223682E (pt) 2012-03-22
CY1111570T1 (el) 2015-10-07
JP5392880B2 (ja) 2014-01-22
ATE541563T1 (de) 2012-02-15
JP2003534266A (ja) 2003-11-18
IL152955A (en) 2010-02-17
TNSN01074A1 (fr) 2005-11-10
CZ303833B6 (cs) 2013-05-22
AU2000250701B2 (en) 2004-07-01
CN1213732C (zh) 2005-08-10
CA2411047C (en) 2009-08-04
DE60144304D1 (de) 2011-05-05
HRP20021025A2 (en) 2004-02-29
DZ3358A1 (fr) 2001-11-29
FR11C0041I1 (de) 2011-04-11
HRP20021025B1 (hr) 2013-11-22
CY2011014I2 (el) 2015-10-07
WO2001089480A1 (en) 2001-11-29
ES2359991T3 (es) 2011-05-30
MEP32108A (en) 2010-10-10
DE122011100049I1 (de) 2012-01-19
MY143733A (en) 2011-07-15
NL300393I2 (en) 2010-02-01
SI1787639T1 (sl) 2011-07-29
US6716414B2 (en) 2004-04-06
PE20011323A1 (es) 2002-01-22
EP1787639A3 (de) 2009-02-25
SI1157689T1 (sl) 2009-06-30
US20020025299A1 (en) 2002-02-28
ES2318217T3 (es) 2009-05-01
ES2320194T3 (es) 2009-05-20
ATE415945T1 (de) 2008-12-15
SA01220126B1 (ar) 2007-04-03
BG107256A (bg) 2003-06-30
AU2000250701A1 (en) 2002-02-21
SK286694B6 (sk) 2009-03-05
US7018618B2 (en) 2006-03-28
NO2019030I1 (no) 2019-07-11
EP1787639B1 (de) 2011-03-23
AU5070100A (en) 2001-12-03
ES2380790T3 (es) 2012-05-18
CZ20023835A3 (cs) 2003-04-16
EP1466594B1 (de) 2008-12-03
SI1466594T1 (sl) 2009-06-30
CY2009009I2 (el) 2014-04-09
CA2411047A1 (en) 2001-11-29
SI2223682T1 (sl) 2012-04-30

Similar Documents

Publication Publication Date Title
ATE541563T1 (de) Stabile arzneimittellösung für druckdosierinhalatoren
DE60130156D1 (de) Inhalator
DE60115699D1 (de) Spender für medikament
DE60141149D1 (de) Medizinisches Inhalations-Gerät
DE60225431D1 (de) Dialysekatheter
DE10192161T1 (de) Medizinischer Führungsdraht
NO20011383L (no) Inhalator
DE50114549D1 (de) Mechanisch stabile darreichungsformen, enthaltend ubichinone
DE50100715D1 (de) Inhalationsvernebler
NO20031597L (no) Medisinske aerosolformuleringer
ATE299859T1 (de) Therapeutisch verwendbare diphenyletherverbindungen
FR2810555B1 (fr) Catheter reutilisable
DE50108753D1 (de) Medizinisches instrument
DE60032946D1 (de) Katheter
DK1407780T3 (da) Farmaceutisk stabile hæmostatiske præparater
DE50102878D1 (de) Medizinisches instrument
DE10196460T1 (de) Selbstzerstör-Spritze
ES1047859Y (es) Dispositivo inhalador nasal.
DK1267974T3 (da) Inhalationsapparat
ES1046532Y (es) Inhalador perfeccionado
DE10295185D2 (de) Anästhesiespritze
DK1330280T3 (da) Lægemiddelinhalator
FI20002119A (fi) Väline nenäverenvuodon hoidossa
DE60232853D1 (de) Nasale Beatmungskanüle
NO20024301D0 (no) Engangspustemaske