ATE478602T1 - Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen - Google Patents
Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationenInfo
- Publication number
- ATE478602T1 ATE478602T1 AT05858653T AT05858653T ATE478602T1 AT E478602 T1 ATE478602 T1 AT E478602T1 AT 05858653 T AT05858653 T AT 05858653T AT 05858653 T AT05858653 T AT 05858653T AT E478602 T1 ATE478602 T1 AT E478602T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- receptor
- precursor
- polypeptide
- alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/321—Arterial hypertension
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63627504P | 2004-12-15 | 2004-12-15 | |
PCT/US2005/045805 WO2007053161A2 (en) | 2004-12-15 | 2005-12-15 | Nucleic acids and polypeptides useful for diagnosing and treating complications of pregnancy |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE478602T1 true ATE478602T1 (de) | 2010-09-15 |
Family
ID=38006337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05858653T ATE478602T1 (de) | 2004-12-15 | 2005-12-15 | Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen |
Country Status (12)
Country | Link |
---|---|
US (1) | US7955805B2 (de) |
EP (1) | EP1839057B1 (de) |
JP (1) | JP2008523816A (de) |
KR (1) | KR20070092737A (de) |
CN (1) | CN101299962A (de) |
AT (1) | ATE478602T1 (de) |
AU (1) | AU2005337873A1 (de) |
BR (1) | BRPI0519096A2 (de) |
CA (1) | CA2591142A1 (de) |
DE (1) | DE602005023216D1 (de) |
HK (1) | HK1115286A1 (de) |
WO (1) | WO2007053161A2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1804836B1 (de) | 2004-09-24 | 2010-11-17 | Beth Israel Deaconess Medical Center | Verfahren zur diagnose und behandlung von schwangerschaftsskomplikationen |
JP5009811B2 (ja) | 2004-12-21 | 2012-08-22 | イェール ユニバーシティ | 子癇前症の検出 |
US7230561B2 (en) * | 2005-01-27 | 2007-06-12 | Micron Technology, Inc. | Programmable integrating ramp generator and method of operating the same |
WO2006102498A2 (en) * | 2005-03-24 | 2006-09-28 | Beth Israel Deaconess Medical Center | Methods of diagnosing fetal trisomy 13 or a risk of fetal trisomy 13 during pregnancy |
WO2007030889A1 (en) * | 2005-09-15 | 2007-03-22 | Victor Voroteliak | Method of diagnosing pre-eclampsia |
US20090286271A1 (en) * | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
AU2008209319A1 (en) * | 2007-01-25 | 2008-07-31 | Crc For Asthma And Airways Ltd | Method of diagnosis |
US20110129845A1 (en) * | 2007-01-29 | 2011-06-02 | Crc For Asthma And Airways Ltd. | Method of diagnosis |
EP2037278A1 (de) * | 2007-09-11 | 2009-03-18 | F.Hoffmann-La Roche Ag | Gefäßmarker bei der Neumodellierung von Herzkrankheiten |
WO2010033553A2 (en) * | 2008-09-16 | 2010-03-25 | University Of Florida Research Foundation Inc. | Gene expression related to preeclampsia |
US9229009B2 (en) | 2008-10-31 | 2016-01-05 | Yale University | Methods and kits for detecting misfolded proteins |
ES2530574T3 (es) * | 2009-01-28 | 2015-03-03 | Ind Tech Res Inst | Biomarcadores asociados a la nefropatía |
EP2625524A4 (de) * | 2010-10-07 | 2014-05-07 | Astute Medical Inc | Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz |
ES2667013T3 (es) * | 2010-11-29 | 2018-05-09 | Mote Marine Laboratory, Inc. | Determinación de las características sexuales de peces usando hormonas peptídicas |
KR101114446B1 (ko) * | 2011-02-25 | 2012-02-24 | 건국대학교 산학협력단 | 프로테오믹스기법을 이용한 임신중독 특이 표지 단백질 및 진단방법 |
CN102192987B (zh) * | 2011-02-25 | 2014-04-02 | 复旦大学附属上海市第五人民医院 | 一种用于妊娠高血压疾病诊断的试剂盒 |
ES2614059T3 (es) | 2011-03-17 | 2017-05-29 | Cedars-Sinai Medical Center | Biomarcador de diagnóstico para predecir las mujeres en riesgo de parto prematuro |
AU2012346594B2 (en) * | 2011-11-30 | 2017-12-21 | Agency For Science, Technology And Research | GM1 ganglioside to Annexin V microparticle polypeptide ratio for biological monitoring |
AU2013207264A1 (en) * | 2012-01-06 | 2014-07-17 | Bg Medicine, Inc. | Use of galectin-3 for risk assessment and detection of preeclampsia and related conditions |
CN104634982B (zh) * | 2013-11-06 | 2016-08-17 | 中国科学院上海生命科学研究院 | Vegf-c在制备败血症及重症细菌感染诊断试剂中的用途 |
CN103760340B (zh) * | 2014-01-28 | 2016-11-23 | 成都创宜生物科技有限公司 | 以flrg作为标志物制备检测工具的应用及检测工具 |
US10324094B2 (en) | 2014-04-10 | 2019-06-18 | Yale University | Methods and compositions for detecting misfolded proteins |
RU2724013C2 (ru) | 2015-06-19 | 2020-06-18 | Сера Прогностикс, Инк. | Пары биологических маркеров для предсказания преждевременных родов |
CN106771266A (zh) * | 2017-01-12 | 2017-05-31 | 广州市丰华生物工程有限公司 | 抑制素a定量检测试剂盒及其制备方法 |
JP6895165B2 (ja) * | 2017-06-06 | 2021-06-30 | 知和 松浦 | α1−アンチキモトリプシンを含むバイオマーカー |
US20210325400A1 (en) * | 2020-04-16 | 2021-10-21 | Denali K. Dahl | Preeclampsia diagnostic devices, systems and methods |
CN111951969A (zh) * | 2020-08-05 | 2020-11-17 | 中翰盛泰生物技术股份有限公司 | Hbp在高危妊娠预测中的应用 |
CN114075281B (zh) * | 2021-11-16 | 2023-04-18 | 福州迈新生物技术开发有限公司 | 抗Inhibin-α蛋白单克隆抗体、细胞系及其制备方法和应用 |
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US5079171A (en) * | 1988-09-15 | 1992-01-07 | Adeza Biomedical Corporation | Determining pregnancy induced hypertension and eclampsia by immunoassay of cellular fibronectin |
US5240848A (en) * | 1988-11-21 | 1993-08-31 | Monsanto Company | Dna sequences encoding human vascular permeability factor having 189 amino acids |
US5238819A (en) * | 1988-12-14 | 1993-08-24 | The Regents Of The University Of California | Diagnostic assay for the detection of preeclampsia |
US5332671A (en) * | 1989-05-12 | 1994-07-26 | Genetech, Inc. | Production of vascular endothelial cell growth factor and DNA encoding same |
US5219739A (en) * | 1989-07-27 | 1993-06-15 | Scios Nova Inc. | DNA sequences encoding bVEGF120 and hVEGF121 and methods for the production of bovine and human vascular endothelial cell growth factors, bVEGF120 and hVEGF121 |
US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
US5660827A (en) * | 1992-03-05 | 1997-08-26 | Board Of Regents, The University Of Texas System | Antibodies that bind to endoglin |
WO1993021319A1 (en) | 1992-04-08 | 1993-10-28 | Cetus Oncology Corporation | HUMANIZED C-erbB-2 SPECIFIC ANTIBODIES |
US5712395A (en) * | 1992-11-13 | 1998-01-27 | Yissum Research Development Corp. | Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis |
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US6410322B1 (en) * | 1993-07-27 | 2002-06-25 | Hybridon Inc | Antisense oligonucleotide inhibition of vascular endothelial growth factor expression |
US5861499A (en) * | 1994-02-10 | 1999-01-19 | Imclone Systems Incorporated | Nucleic acid molecules encoding the variable or hypervariable region of a monoclonal antibody that binds to an extracellular domain |
US5543138A (en) * | 1994-03-10 | 1996-08-06 | Genetics Institute, Inc. | Methods of diagnosing and treating preeclampsia |
GB9512994D0 (en) * | 1995-06-26 | 1995-08-30 | Brf International | Method for quantitative measurement of an enzyme linked immunosorbent assay |
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US5830879A (en) * | 1995-10-02 | 1998-11-03 | St. Elizabeth's Medical Center Of Boston, Inc. | Treatment of vascular injury using vascular endothelial growth factor |
US6100071A (en) * | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
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JP4318752B2 (ja) * | 1996-05-31 | 2009-08-26 | ヘルス・リサーチ・インコーポレーテッド | 抗エンドグリンモノクローナル抗体および抗血管新生治療におけるその使用 |
US6620590B2 (en) * | 1996-07-11 | 2003-09-16 | Isis Innovation Limited | Diagnosis of pre-eclampsia |
EP0951298A1 (de) | 1996-12-23 | 1999-10-27 | Cambridge University Technical Services Limited | Diagnose und behandlung von pathologischen schwangerschaften |
EP0968430A1 (de) * | 1997-03-07 | 2000-01-05 | Mount Sinai Hospital Corporation | Verfahrens zur diagnose einer benötigten regulierung der trophoblastinvasion |
EP1417971A3 (de) | 1998-09-09 | 2004-06-30 | Scios Inc. | Verwendung eines angiogenen Faktors zur Behandlung von mikrovaskulären Angiopathien |
US7030083B2 (en) * | 1998-09-09 | 2006-04-18 | University Of Washington | Treatment of eclampsia and preeclampsia |
US6677300B1 (en) * | 1998-09-09 | 2004-01-13 | Scios, Inc. | Treatment of microvascular angiopathies |
US6245577B1 (en) * | 1998-09-11 | 2001-06-12 | Midland Bioproducts Corporation | IgG antibody testing method |
EP1016726A1 (de) * | 1998-12-30 | 2000-07-05 | Introgene B.V. | Gentherapie zur Förderung der Angiogenesis |
GB0008269D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
GB0026823D0 (en) * | 2000-11-02 | 2000-12-20 | King S College London | Diagnosis of pre-eclampsia |
WO2002070535A1 (en) * | 2001-03-01 | 2002-09-12 | Isis Pharmaceuticals, Inc. | Antisense modulation of recql5 expression |
EP1466016A2 (de) * | 2002-01-09 | 2004-10-13 | Riken Institute Of Physical And Chemical Research | Krebsprofile |
US7335362B2 (en) | 2002-07-19 | 2008-02-26 | Beth Israel Deaconess Medical Center | Methods of treating pre-eclampsia or eclampsia |
OA12890A (en) * | 2002-07-19 | 2006-10-13 | Beth Israel Hospital | Methods of diagnosing and treating pre-eclampsia or eclampsia. |
US7435419B2 (en) | 2002-07-19 | 2008-10-14 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating pre-eclampsia or eclampsia |
TW200413725A (en) * | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Method for diagnosing non-small cell lung cancers |
CN101245376A (zh) * | 2003-01-17 | 2008-08-20 | 香港中文大学 | 作为妊娠相关病症的诊断标志物的循环mRNA |
US20050266409A1 (en) | 2003-02-04 | 2005-12-01 | Wyeth | Compositions and methods for diagnosing, preventing, and treating cancers |
US7191068B2 (en) * | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
DE10333105B3 (de) * | 2003-07-21 | 2005-05-25 | OCé PRINTING SYSTEMS GMBH | Einrichtung zur Einstellung der Spannung einer Materialbahn, die durch eine die Materialbahn bearbeitende Prozessstation bewegt wird |
WO2005017192A2 (en) * | 2003-08-14 | 2005-02-24 | The General Hospital Corporation | Screening for gestational disorders |
US7344892B2 (en) * | 2003-09-23 | 2008-03-18 | Beth Israel Deaconess Medical Center, Inc. | Screening for gestational disorders |
EP1804836B1 (de) | 2004-09-24 | 2010-11-17 | Beth Israel Deaconess Medical Center | Verfahren zur diagnose und behandlung von schwangerschaftsskomplikationen |
US7740849B2 (en) * | 2004-09-24 | 2010-06-22 | Beth Israel Deaconess Medical Center | Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders |
JP5009811B2 (ja) * | 2004-12-21 | 2012-08-22 | イェール ユニバーシティ | 子癇前症の検出 |
WO2008030283A1 (en) | 2006-05-31 | 2008-03-13 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating complications of pregnancy |
-
2005
- 2005-12-15 AT AT05858653T patent/ATE478602T1/de not_active IP Right Cessation
- 2005-12-15 JP JP2007546973A patent/JP2008523816A/ja active Pending
- 2005-12-15 WO PCT/US2005/045805 patent/WO2007053161A2/en active Application Filing
- 2005-12-15 DE DE602005023216T patent/DE602005023216D1/de active Active
- 2005-12-15 EP EP05858653A patent/EP1839057B1/de active Active
- 2005-12-15 KR KR1020077016078A patent/KR20070092737A/ko not_active Application Discontinuation
- 2005-12-15 US US11/300,928 patent/US7955805B2/en active Active
- 2005-12-15 BR BRPI0519096-7A patent/BRPI0519096A2/pt not_active IP Right Cessation
- 2005-12-15 AU AU2005337873A patent/AU2005337873A1/en not_active Abandoned
- 2005-12-15 CA CA002591142A patent/CA2591142A1/en not_active Abandoned
- 2005-12-15 CN CNA2005800483839A patent/CN101299962A/zh active Pending
-
2008
- 2008-04-02 HK HK08103714.1A patent/HK1115286A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20060166277A1 (en) | 2006-07-27 |
EP1839057B1 (de) | 2010-08-25 |
BRPI0519096A2 (pt) | 2008-12-23 |
WO2007053161A3 (en) | 2007-11-29 |
US7955805B2 (en) | 2011-06-07 |
EP1839057A2 (de) | 2007-10-03 |
JP2008523816A (ja) | 2008-07-10 |
CN101299962A (zh) | 2008-11-05 |
AU2005337873A1 (en) | 2007-05-10 |
WO2007053161A2 (en) | 2007-05-10 |
DE602005023216D1 (de) | 2010-10-07 |
HK1115286A1 (en) | 2008-11-28 |
EP1839057A4 (de) | 2008-12-31 |
KR20070092737A (ko) | 2007-09-13 |
CA2591142A1 (en) | 2007-05-10 |
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