Luchetti et al., 2004 - Google Patents
Scleroderma fibroblasts constitutively express the long pentraxin PTX3Luchetti et al., 2004
View PDF- Document ID
- 5017250867272787283
- Author
- Luchetti M
- Sambo P
- Majlingova P
- Baroni S
- Peri G
- Paroncini P
- Introna M
- Stoppacciaro A
- Mantovani A
- Gabrielli A
- Publication year
- Publication venue
- Clinical and experimental rheumatology
External Links
Snippet
Objective. PTX3 is a secreted molecule which consists of a C-terminal domain similar to classical pentraxins (eg C-reactive protein) and of an unrelated N-terminal domain. Unlike the classical pentraxins, PTX3 is expressed in response to IL-1 and TNF-but not to IL-6. The …
- 102100002855 PITX3 0 title abstract description 104
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
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