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ATE472540T1 - Als h3-liganden geeignete 3- oder 4- monosubstituierte phenol- und thiophenol-derivate - Google Patents

Als h3-liganden geeignete 3- oder 4- monosubstituierte phenol- und thiophenol-derivate

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Publication number
ATE472540T1
ATE472540T1 AT05718521T AT05718521T ATE472540T1 AT E472540 T1 ATE472540 T1 AT E472540T1 AT 05718521 T AT05718521 T AT 05718521T AT 05718521 T AT05718521 T AT 05718521T AT E472540 T1 ATE472540 T1 AT E472540T1
Authority
AT
Austria
Prior art keywords
ligands
derivatives suitable
thiophenol derivatives
monosubstituted phenol
monosubstituted
Prior art date
Application number
AT05718521T
Other languages
English (en)
Inventor
P Bernardelli
A M Cronin
A Denis
S M Denton
H Jacobelli
M I Kemp
E Lorthiois
F Rousseau
D Serradeil-Civit
F Vergne
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP04291187A external-priority patent/EP1593679A1/de
Priority claimed from GB0504564A external-priority patent/GB0504564D0/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE472540T1 publication Critical patent/ATE472540T1/de

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    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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AT05718521T 2004-05-07 2005-04-19 Als h3-liganden geeignete 3- oder 4- monosubstituierte phenol- und thiophenol-derivate ATE472540T1 (de)

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EP04291187A EP1593679A1 (de) 2004-05-07 2004-05-07 Als H3-Liganden geeignete 3- oder 4-monosubstituierte Phenol-Derivate
GB0504564A GB0504564D0 (en) 2005-03-04 2005-03-04 New compounds
PCT/IB2005/001114 WO2005108384A1 (en) 2004-05-07 2005-04-19 3- or 4-monosubstituted phenol and thiophenol derivatives useful as h3 ligands

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CN101553217A (zh) 2005-07-06 2009-10-07 塞普拉科公司 艾司佐匹克隆与反式4－(3,4－二氯苯基)－1,2,3,4－四氢－n－甲基－1－萘胺或反式4－(3,4－二氯苯基)－1,2,3,4－四氢－1－萘胺的组合以及治疗绝经期和心境障碍、焦虑症和认知障碍的方法
WO2007045989A1 (en) * 2005-10-20 2007-04-26 Pfizer Limited Pyridyl derivatives useful as h3 ligands
CA2636275C (en) 2006-01-06 2013-02-12 Sepracor Inc. Tetralone-based monoamine reuptake inhibitors
BRPI0706365A2 (pt) 2006-01-06 2011-03-22 Sepracor Inc Cicloalquilaminas como inibidores da recaptação de monoamina
PT2013835E (pt) 2006-03-31 2016-01-06 Sunovion Pharmaceuticals Inc Preparação de amidas and aminas quirais
AU2007236115A1 (en) 2006-04-11 2007-10-18 Novartis Ag Organic compounds
US9108948B2 (en) * 2006-06-23 2015-08-18 Abbvie Inc. Cyclopropyl amine derivatives
NZ611323A (en) * 2006-06-23 2014-10-31 Abbvie Bahamas Ltd Cyclopropyl amine derivatives as histamin h3 receptor modulators
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
BRPI0718874A2 (pt) * 2006-12-22 2015-06-23 Novartis Ag Compostos orgânicos
US7902252B2 (en) 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
BRPI0811639A2 (pt) 2007-05-31 2014-09-30 Sepracor Inc Cicloaquilaminas fenil substituídas como inibidores da recaptação de monoamina
TW201039822A (en) 2009-02-06 2010-11-16 Taisho Pharmaceutical Co Ltd Dihydroquinolinone derivatives
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WO2014095534A1 (en) * 2012-12-19 2014-06-26 Basf Se New substituted triazoles and imidazoles and their use as fungicides
US9365511B2 (en) * 2013-01-09 2016-06-14 Arena Pharmaceuticals, Inc. Biphenyl-ethyl-pyrrolidine derivatives as histamine H3 receptor modulators for the treatment of cognitive disorders
TWI663159B (zh) * 2013-12-10 2019-06-21 美商健臻公司 原肌球蛋白相關之激酶（ｔｒｋ）抑制劑
TWI696621B (zh) 2014-12-18 2020-06-21 美商健臻公司 原肌球蛋白相關激酶（ｔｒｋ）抑制劑之醫藥調配物
CN113336715B (zh) * 2021-08-04 2021-11-23 山东海利尔化工有限公司 一种含二氧戊环的三唑类化合物及其中间体的制备方法

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CN1950351A (zh) 2007-04-18
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EA011161B1 (ru) 2009-02-27
RS51403B (en) 2011-02-28
WO2005108384A1 (en) 2005-11-17
CN1950351B (zh) 2012-01-18
PE20060237A1 (es) 2006-04-01
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ES2346665T3 (es) 2010-10-19
MXPA06012819A (es) 2007-01-26
SV2006002107A (es) 2006-06-26
AU2005240846A1 (en) 2005-11-17
UY28883A1 (es) 2005-12-30
AP2006003772A0 (en) 2006-10-31
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JP2008050365A (ja) 2008-03-06
IL178433A0 (en) 2007-02-11
PL1747210T3 (pl) 2010-11-30
BRPI0510664B1 (pt) 2020-04-07
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DK1747210T3 (da) 2010-09-27
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KR20060133091A (ko) 2006-12-22
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