US20080213778A1
(en)
|
1998-12-30 |
2008-09-04 |
Millennium Pharmaceuticals, Inc. |
Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses
|
US7041474B2
(en)
|
1998-12-30 |
2006-05-09 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid encoding human tango 509
|
ATE353365T1
(de)
|
1999-08-23 |
2007-02-15 |
Dana Farber Cancer Inst Inc |
Neue b7-4 moleküle und deren verwendungen
|
BR0013581A
(pt)
|
1999-08-23 |
2002-07-02 |
Dana Faber Cancer Inst Inc |
Pd-1, um receptor para b7-4, e usos para isto
|
WO2001039722A2
(en)
*
|
1999-11-30 |
2001-06-07 |
Mayo Foundation For Medical Education And Research |
B7-h1, a novel immunoregulatory molecule
|
US6803192B1
(en)
*
|
1999-11-30 |
2004-10-12 |
Mayo Foundation For Medical Education And Research |
B7-H1, a novel immunoregulatory molecule
|
US20010055593A1
(en)
*
|
2000-03-14 |
2001-12-27 |
Joseph Sypek |
Use of rapamycin and agents that inhibit B7 activity in immunomodulation
|
US20030031675A1
(en)
|
2000-06-06 |
2003-02-13 |
Mikesell Glen E. |
B7-related nucleic acids and polypeptides useful for immunomodulation
|
CA2412377A1
(en)
|
2000-06-06 |
2001-12-13 |
Bristol-Myers Squibb Company |
B7-related nucleic acids and polypeptides and their uses for immunomodulation
|
ES2402546T3
(es)
|
2000-06-28 |
2013-05-06 |
Genetics Institute, Llc |
Moléculas PD-L2: nuevos ligandos de PD-1 y usos de lso mismos
|
WO2002079499A1
(en)
|
2001-04-02 |
2002-10-10 |
Wyeth |
Pd-1, a receptor for b7-4, and uses therefor
|
AR036993A1
(es)
|
2001-04-02 |
2004-10-20 |
Wyeth Corp |
Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
|
AU2002258941A1
(en)
*
|
2001-04-20 |
2002-11-05 |
Mayo Foundation For Medical Education And Research |
Methods of enhancing cell responsiveness
|
DK2206517T3
(da)
|
2002-07-03 |
2023-11-06 |
Ono Pharmaceutical Co |
Immunpotentierende sammensætninger omfattende af anti-PD-L1-antistoffer
|
US7432351B1
(en)
|
2002-10-04 |
2008-10-07 |
Mayo Foundation For Medical Education And Research |
B7-H1 variants
|
US7449300B2
(en)
|
2002-11-21 |
2008-11-11 |
Mayo Foundation For Medical Education And Research |
Detection of antibodies specific for B7-H1 in subjects with diseases or pathological conditions mediated by activated T cells
|
CA2508660C
(en)
|
2002-12-23 |
2013-08-20 |
Wyeth |
Antibodies against pd-1 and uses therefor
|
MX2007004176A
(es)
|
2004-10-06 |
2007-06-15 |
Mayo Foundation |
B7-h1 y metodos de diagnosis, prognosis, y tratamiento de cancer.
|
EP2161336B2
(de)
|
2005-05-09 |
2017-03-29 |
ONO Pharmaceutical Co., Ltd. |
Humane monoklonale Antikörper für den programmierten Tod 1 (PD-1) und Verfahren zur Behandlung von Krebs mit PD-1-Antikörpern allein oder in Kombination mit anderen Immunotherapeutika
|
KR101600225B1
(ko)
|
2005-06-08 |
2016-03-04 |
다나-파버 캔서 인스티튜트 인크. |
예정 세포사 1(pd-1) 경로를 억제함으로써 지속 감염 및 암을 치료하기 위한 방법 및 조성물
|
ES2547463T3
(es)
*
|
2005-06-17 |
2015-10-06 |
Merck Sharp & Dohme Corp. |
Moléculas de unión a ILT3 y usos de las mismas
|
PT1907424E
(pt)
|
2005-07-01 |
2015-10-09 |
Squibb & Sons Llc |
Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1)
|
NZ568015A
(en)
|
2005-12-08 |
2012-03-30 |
Medarex Inc |
Human monoclonal antibodies to O8E
|
EP2061504A4
(de)
*
|
2006-09-20 |
2010-01-27 |
Univ Johns Hopkins |
Kombinationstherapie für krebs und infektionskrankheiten mit anti-b7-h1-antikörpern
|
AU2007339897B2
(en)
*
|
2006-12-27 |
2013-02-14 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for the treatment of infections and tumors
|
ES2616355T3
(es)
|
2007-06-18 |
2017-06-12 |
Merck Sharp & Dohme B.V. |
Anticuerpos para el receptor humano de muerte programada PD-1
|
US8563314B2
(en)
*
|
2007-09-27 |
2013-10-22 |
Sangamo Biosciences, Inc. |
Methods and compositions for modulating PD1
|
US8062852B2
(en)
|
2007-10-01 |
2011-11-22 |
The Children's Hospital And Regional Medical Center |
Detection and treatment of autoimmune disorders
|
WO2009059328A2
(en)
*
|
2007-11-02 |
2009-05-07 |
The Johns Hopkins University |
Multi- component l2 vaccine for prevention of human papillomavirus infection
|
HUE028582T2
(en)
*
|
2008-11-28 |
2016-12-28 |
Univ Emory |
Method for determining the efficacy of PD-1 antagonists
|
KR20180089573A
(ko)
|
2008-12-09 |
2018-08-08 |
제넨테크, 인크. |
항-pd-l1 항체 및 t 세포 기능을 향상시키기 위한 그의 용도
|
EP2399934B1
(de)
*
|
2009-02-20 |
2017-09-06 |
The University of Tokyo |
Neuer monoklonaler antikörper und verwendung davon
|
WO2010102278A1
(en)
*
|
2009-03-06 |
2010-09-10 |
President And Fellows Of Harvard College |
Methods and compositions for the generation and maintenance of regulatory t cells
|
US8993731B2
(en)
|
2010-03-11 |
2015-03-31 |
Ucb Biopharma Sprl |
PD-1 antibody
|
TW201134488A
(en)
*
|
2010-03-11 |
2011-10-16 |
Ucb Pharma Sa |
PD-1 antibodies
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
US9783578B2
(en)
|
2010-06-25 |
2017-10-10 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
JP6072771B2
(ja)
|
2011-04-20 |
2017-02-01 |
メディミューン,エルエルシー |
B7−h1およびpd−1に結合する抗体およびその他の分子
|
EP2717895A1
(de)
|
2011-06-08 |
2014-04-16 |
Aurigene Discovery Technologies Limited |
Therapeutische verbindungen für immunmodulation
|
EP2537933A1
(de)
|
2011-06-24 |
2012-12-26 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Auf IL-15- und IL-15Ralpha-Sushi-Domäne basierende Immunozytokine
|
US9856320B2
(en)
|
2012-05-15 |
2018-01-02 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting PD-1/PD-L1 signaling
|
CN110079599B
(zh)
|
2013-03-15 |
2024-06-04 |
豪夫迈·罗氏有限公司 |
治疗pd-1和pd-l1相关疾患的生物标志物和方法
|
WO2014194293A1
(en)
|
2013-05-30 |
2014-12-04 |
Amplimmune, Inc. |
Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof
|
PT3702373T
(pt)
|
2013-09-13 |
2022-09-27 |
Beigene Switzerland Gmbh |
Anticorpos anti-pd1 e a sua utilização como agentes terapêuticos e de diagnóstico
|
LT3508502T
(lt)
|
2013-09-20 |
2023-07-10 |
Bristol-Myers Squibb Company |
Anti-lag-3 antikūnų ir anti-pd-1 antikūnų derinys, skirtas navikų gydymui
|
US10570204B2
(en)
|
2013-09-26 |
2020-02-25 |
The Medical College Of Wisconsin, Inc. |
Methods for treating hematologic cancers
|
DE202014010499U1
(de)
|
2013-12-17 |
2015-10-20 |
Kymab Limited |
Targeting von humaner PCSK9 zur Cholesterinbehandlung
|
RU2761663C2
(ru)
|
2013-12-20 |
2021-12-13 |
Интервет Интернэшнл Б.В. |
Антитела к pd-1 собак
|
HRP20220214T1
(hr)
|
2014-01-15 |
2022-04-29 |
Kadmon Corporation, Llc |
Imunomodulacijska sredstva
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
EP3149042B1
(de)
|
2014-05-29 |
2019-08-28 |
Spring Bioscience Corporation |
Pd-l1-antikörper und verwendungen davon
|
JP6449338B2
(ja)
|
2014-06-06 |
2019-01-09 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
グルココルチコイド誘導腫瘍壊死因子受容体(gitr)に対する抗体およびその使用
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
TWI687438B
(zh)
|
2014-07-03 |
2020-03-11 |
英屬開曼群島商百濟神州生物科技有限公司 |
抗pd-l1抗體及其作為治療及診斷之用途
|
JP6760919B2
(ja)
|
2014-07-09 |
2020-09-23 |
バーディー バイオファーマシューティカルズ インコーポレイテッド |
腫瘍を治療するための抗pd−l1組み合わせ
|
SG11201700207WA
(en)
|
2014-07-11 |
2017-02-27 |
Genentech Inc |
Anti-pd-l1 antibodies and diagnostic uses thereof
|
AU2015292678B2
(en)
|
2014-07-22 |
2020-10-22 |
Cb Therapeutics, Inc. |
Anti-PD-1 antibodies
|
SG10201901057UA
(en)
|
2014-08-05 |
2019-03-28 |
Cb Therapeutics Inc |
Anti-pd-l1 antibodies
|
CN112546238A
(zh)
|
2014-09-01 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
WO2016040892A1
(en)
|
2014-09-13 |
2016-03-17 |
Novartis Ag |
Combination therapies
|
TWI716362B
(zh)
|
2014-10-14 |
2021-01-21 |
瑞士商諾華公司 |
針對pd-l1之抗體分子及其用途
|
MX2017006323A
(es)
|
2014-11-21 |
2017-08-21 |
Bristol Myers Squibb Co |
Anticuerpos que comprenden regiones constantes pesadas modificadas.
|
CA2968357A1
(en)
|
2014-11-21 |
2016-05-26 |
Bristol-Myers Squibb Company |
Antibodies against cd73 and uses thereof
|
EP3234193B1
(de)
|
2014-12-19 |
2020-07-15 |
Massachusetts Institute of Technology |
Molekulare biomarker für krebsimmuntherapie
|
TN2017000267A1
(en)
|
2014-12-23 |
2018-10-19 |
Bristol Myers Squibb Co |
Antibodies to tigit
|
ES2791950T3
(es)
|
2015-02-03 |
2020-11-06 |
Ventana Med Syst Inc |
Ensayo histoquímico para evaluar la expresión del ligando de muerte programada 1 (PD-L1)
|
WO2016127052A1
(en)
|
2015-02-05 |
2016-08-11 |
Bristol-Myers Squibb Company |
Cxcl11 and smica as predictive biomarkers for efficacy of anti-ctla4 immunotherapy
|
EP3265090A4
(de)
|
2015-03-06 |
2018-08-01 |
Beyondspring Pharmaceuticals Inc. |
Verfahren zur behandlung von krebs im zusammenhang mit einer ras-mutation
|
SG11201707128TA
(en)
|
2015-03-06 |
2017-09-28 |
Beyondspring Pharmaceuticals Inc |
Method of treating a brain tumor
|
JP6826055B2
(ja)
|
2015-03-13 |
2021-02-03 |
サイトメックス セラピューティクス インコーポレイテッド |
抗pdl1抗体、活性化可能抗pdl1抗体、およびその使用方法
|
ES2936317T3
(es)
|
2015-05-29 |
2023-03-16 |
Bristol Myers Squibb Co |
Anticuerpos contra OX40 y usos de los mismos
|
WO2016196218A1
(en)
|
2015-05-31 |
2016-12-08 |
Curegenix Corporation |
Combination compositions for immunotherapy
|
TW201709929A
(zh)
|
2015-06-12 |
2017-03-16 |
宏觀基因股份有限公司 |
治療癌症的聯合療法
|
EP3313886A1
(de)
|
2015-06-29 |
2018-05-02 |
The Rockefeller University |
Antikörper gegen cd40 mit erhöhter agonistischer aktivität
|
AU2016294440B2
(en)
|
2015-07-13 |
2022-10-13 |
Cytomx Therapeutics, Inc |
Anti-PD-1 antibodies, activatable anti-PD-1 antibodies, and methods of use thereof
|
EP3334726B1
(de)
|
2015-07-13 |
2022-03-16 |
Beyondspring Pharmaceuticals, Inc. |
Pinabulin-zusammensetzungen
|
CN107847574B
(zh)
|
2015-07-30 |
2023-05-23 |
宏观基因有限公司 |
Pd-1结合分子和其使用方法
|
AR105654A1
(es)
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
MX2018004177A
(es)
|
2015-10-08 |
2018-09-11 |
Macrogenics Inc |
Terapia de combinacion para el tratamiento de cancer.
|
US11702477B2
(en)
|
2015-11-06 |
2023-07-18 |
Orionis Biosciences BV |
Bi-functional chimeric proteins and uses thereof
|
WO2017087678A2
(en)
|
2015-11-19 |
2017-05-26 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
EA201891178A1
(ru)
|
2015-12-14 |
2019-01-31 |
Макродженикс, Инк. |
Биспецифичные молекулы, обладающие иммунореактивностью в отношении pd-1 и ctla-4, и способы их применения
|
CN116063492A
(zh)
|
2015-12-15 |
2023-05-05 |
昂科医药 |
嵌合和人源化抗人类ctla4单克隆抗体和其用途
|
US11091556B2
(en)
|
2015-12-18 |
2021-08-17 |
Intervet Inc. |
Caninized human antibodies to human IL-4R alpha
|
WO2017112775A1
(en)
|
2015-12-22 |
2017-06-29 |
Regeneron Pharmaceuticals, Inc. |
Combination of anti-pd-1 antibodies and bispecific anti-cd20/anti-cd3 antibodies to treat cancer
|
EP3998281A1
(de)
|
2016-02-05 |
2022-05-18 |
Orionis Biosciences BV |
Cd8-bindemittel
|
MX2018009413A
(es)
|
2016-02-08 |
2019-05-15 |
Beyondspring Pharmaceuticals Inc |
Composiciones que contienen tucaresol o sus analogos.
|
MX2018010473A
(es)
|
2016-03-04 |
2018-09-28 |
Squibb Bristol Myers Co |
Terapia de combinacion con anticuerpos anti cumulo de diferenciacion 73 (cd73).
|
SG11201808821WA
(en)
|
2016-04-18 |
2018-11-29 |
Celldex Therapeutics Inc |
Agonistic antibodies that bind human cd40 and uses thereof
|
CN109563141A
(zh)
|
2016-05-13 |
2019-04-02 |
奥里尼斯生物科学公司 |
对非细胞结构的治疗性靶向
|
WO2017194783A1
(en)
|
2016-05-13 |
2017-11-16 |
Orionis Biosciences Nv |
Targeted mutant interferon-beta and uses thereof
|
TWI755395B
(zh)
|
2016-05-13 |
2022-02-21 |
美商再生元醫藥公司 |
抗-pd-1抗體與輻射治療癌症之組合
|
US10994033B2
(en)
|
2016-06-01 |
2021-05-04 |
Bristol-Myers Squibb Company |
Imaging methods using 18F-radiolabeled biologics
|
EP4253419A3
(de)
|
2016-06-02 |
2024-05-22 |
Ultimovacs ASA |
Impfstoff in kombination mit einen antagonist eines immun-checkpoint-hemmers zur verwendung in der krebsbehandlung
|
KR20240091084A
(ko)
|
2016-06-06 |
2024-06-21 |
비욘드스프링 파마수티컬스, 인코포레이티드. |
호중구감소증을 줄이는 조성물 및 방법
|
AU2017293423B2
(en)
|
2016-07-05 |
2023-05-25 |
Beigene, Ltd. |
Combination of a PD-1 antagonist and a RAF inhibitor for treating cancer
|
CN117683135A
(zh)
|
2016-07-14 |
2024-03-12 |
百时美施贵宝公司 |
针对tim3的抗体及其用途
|
EP3500299B1
(de)
|
2016-08-19 |
2023-12-13 |
BeiGene Switzerland GmbH |
Kombination von zanubrutinib mit einem anti-cd20 oder anti-pd-1 antikörper zur verwendung in der behandlung von krebs
|
IL306104A
(en)
|
2016-09-14 |
2023-11-01 |
Abbvie Biotherapeutics Inc |
Antibodies against (CD27) PD-1
|
EP3529264B1
(de)
|
2016-10-24 |
2022-03-09 |
Orionis Biosciences BV |
Zielgerichtetes mutantes interferon-gamma und verwendungen davon
|
WO2018129381A1
(en)
|
2017-01-06 |
2018-07-12 |
Beyondspring Pharmaceuticals, Inc. |
Tubulin binding compounds and therapeutic use thereof
|
CN110461847B
(zh)
|
2017-01-25 |
2022-06-07 |
百济神州有限公司 |
(S)-7-(1-(丁-2-炔酰基)哌啶-4-基)-2-(4-苯氧基苯基)-4,5,6,7-四氢吡唑并[1,5-a]嘧啶-3-甲酰胺的结晶形式、其制备及用途
|
SG11201907023UA
(en)
|
2017-02-01 |
2019-08-27 |
Beyondspring Pharmaceuticals Inc |
Method of reducing neutropenia
|
KR102642385B1
(ko)
|
2017-02-06 |
2024-03-04 |
오리오니스 바이오사이언시스 엔브이 |
표적화된 키메라 단백질 및 이의 용도
|
CN110573172A
(zh)
|
2017-02-06 |
2019-12-13 |
奥里尼斯生物科学有限公司 |
靶向的工程化干扰素及其用途
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
US11760777B2
(en)
|
2017-04-26 |
2023-09-19 |
Bristol-Myers Squibb Company |
Methods of antibody production that minimize disulfide bond reduction
|
KR20200006115A
(ko)
|
2017-05-16 |
2020-01-17 |
브리스톨-마이어스 스큅 컴퍼니 |
항-gitr 효능제 항체에 의한 암의 치료
|
US20200299400A1
(en)
|
2017-05-25 |
2020-09-24 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
BR112019021847A2
(pt)
|
2017-05-30 |
2020-06-02 |
Bristol-Myers Squibb Company |
Composições compreendendo um anticorpo anti-lag-3 ou um anticorpo anti-lag-3 e um anticorpo anti-pd-1 ou anti-pd-l1
|
LT3631454T
(lt)
|
2017-05-30 |
2023-11-27 |
Bristol-Myers Squibb Company |
Lag-3 atžvilgiu teigiamų navikų gydymas
|
BR112019018759A2
(pt)
|
2017-05-30 |
2020-05-05 |
Bristol-Myers Squibb Company |
composições compreendendo uma combinação de um anticorpo anti-lag-3, um inibidor da via pd-1, e um agente imunoterápico
|
WO2018222949A1
(en)
|
2017-06-01 |
2018-12-06 |
Cytomx Therapeutics, Inc. |
Activatable anti-pdl1 antibodies, and methods of use thereof
|
AU2018290532A1
(en)
|
2017-06-26 |
2019-11-21 |
Beigene, Ltd. |
Immunotherapy for hepatocellular carcinoma
|
EP3645040A4
(de)
|
2017-06-27 |
2021-05-05 |
Neuracle Science Co., Ltd |
Verwendung von anti-fam19a5-antikörpern zur krebsbehandlung
|
EP3694552A1
(de)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap-antikörper und verwendungen davon
|
EP3704159A1
(de)
|
2017-11-01 |
2020-09-09 |
Bristol-Myers Squibb Company |
Immunstimulatorische agonistische antikörper zur verwendung bei der krebsbehandlung
|
CN111801334B
(zh)
|
2017-11-29 |
2023-06-09 |
百济神州瑞士有限责任公司 |
使用包含btk抑制剂的组合治疗惰性或侵袭性b-细胞淋巴瘤
|
KR20200103761A
(ko)
|
2017-12-27 |
2020-09-02 |
브리스톨-마이어스 스큅 컴퍼니 |
항-cd40 항체 및 그의 용도
|
AU2019207812A1
(en)
|
2018-01-12 |
2020-07-23 |
Bristol-Myers Squibb Company |
Combination therapy with anti-IL-8 antibodies and anti-PD-1 antibodies for treating cancer
|
EP3737700A1
(de)
|
2018-01-12 |
2020-11-18 |
Bristol-Myers Squibb Company |
Antikörper gegen tim3 und verwendungen davon
|
AU2019210332A1
(en)
|
2018-01-22 |
2020-09-10 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
BR112020014960A2
(pt)
|
2018-01-24 |
2020-12-22 |
Beyondspring Pharmaceuticals, Inc. |
Composição e método para redução de trombocitopenia
|
US20200405806A1
(en)
|
2018-02-08 |
2020-12-31 |
Bristol-Myers Squibb Company |
Combination of a tetanus toxoid, anti-ox40 antibody and/or anti-pd-1 antibody to treat tumors
|
JP7474709B2
(ja)
|
2018-02-27 |
2024-04-25 |
インサイト・コーポレイション |
A2a/a2b阻害剤としてのイミダゾピリミジン及びトリアゾロピリミジン
|
MX2020009786A
(es)
|
2018-03-21 |
2020-10-12 |
Five Prime Therapeutics Inc |
Anticuerpos de union a supresor de la activacion de celulas t que contiene el dominio variable de inmunoglobulina (vista) a ph acido.
|
JP2021521182A
(ja)
|
2018-04-12 |
2021-08-26 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Cd73アンタゴニストとpd−1/pd−l1軸アンタゴニストの組み合わせ治療
|
US20210198374A1
(en)
|
2018-04-17 |
2021-07-01 |
Celldex Therapeutics, Inc. |
Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs
|
MA52940A
(fr)
|
2018-05-18 |
2021-04-28 |
Incyte Corp |
Dérivés de pyrimidine fusionnés utilisés en tant qu'inhibiteurs de a2a/a2b
|
CA3104467A1
(en)
|
2018-06-20 |
2019-12-26 |
Incyte Corporation |
Anti-pd-1 antibodies and uses thereof
|
AU2019297361B2
(en)
|
2018-07-05 |
2024-06-27 |
Incyte Corporation |
Fused pyrazine derivatives as A2A / A2B inhibitors
|
CN113056483A
(zh)
|
2018-07-09 |
2021-06-29 |
戊瑞治疗有限公司 |
结合到ilt4的抗体
|
TW202028235A
(zh)
|
2018-07-11 |
2020-08-01 |
美商戊瑞治療有限公司 |
於酸性ph結合至含免疫球蛋白v域之t細胞活化抑制子(vista)之抗體
|
US20210277135A1
(en)
|
2018-07-13 |
2021-09-09 |
Bristol-Myers Squibb Company |
Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a method of treating a cancer or a solid tumor
|
BR112021000727A2
(pt)
|
2018-07-20 |
2021-04-13 |
Surface Oncology, Inc. |
Composições anti-cd112r e métodos
|
EP3826660A1
(de)
|
2018-07-26 |
2021-06-02 |
Bristol-Myers Squibb Company |
Lag-3-kombinationstherapie zur behandlung von krebs
|
WO2020033791A1
(en)
|
2018-08-09 |
2020-02-13 |
Verseau Therapeutics, Inc. |
Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof
|
JP2022504839A
(ja)
|
2018-10-10 |
2022-01-13 |
ティロス・セラピューティクス・インコーポレイテッド |
抗lap抗体変異体及びその使用
|
US11046769B2
(en)
|
2018-11-13 |
2021-06-29 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
TW202028222A
(zh)
|
2018-11-14 |
2020-08-01 |
美商Ionis製藥公司 |
Foxp3表現之調節劑
|
KR20210093950A
(ko)
|
2018-11-16 |
2021-07-28 |
네오이뮨텍, 인코퍼레이티드 |
Il-7 단백질 및 면역 관문 저해제의 조합으로 종양을 치료하는 방법
|
EP3887397A1
(de)
|
2018-11-28 |
2021-10-06 |
Bristol-Myers Squibb Company |
Antikörper mit modifizierten schweren konstanten regionen
|
TWI829857B
(zh)
|
2019-01-29 |
2024-01-21 |
美商英塞特公司 |
作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
KR20220081977A
(ko)
|
2019-09-18 |
2022-06-16 |
몰레큘러 템플레이츠, 인코퍼레이션. |
시가 독소 a 서브유닛 스캐폴드를 포함하는 pd-l1 결합분자(pd-l1 binding molecules comprising shiga toxin a subunit scaffolds)
|
WO2021055816A1
(en)
|
2019-09-18 |
2021-03-25 |
Molecular Templates, Inc. |
Pd-l1 binding molecules comprising shiga toxin a subunit scaffolds
|
CA3149719A1
(en)
|
2019-09-19 |
2021-03-25 |
Bristol-Myers Squibb Company |
Antibodies binding to vista at acidic ph
|
WO2021064567A1
(en)
|
2019-09-30 |
2021-04-08 |
Astrazeneca Ab |
Combination treatment for cancer
|
WO2021090146A1
(en)
|
2019-11-04 |
2021-05-14 |
Astrazeneca Ab |
Combination therapy for treating cancer
|
EP4058465A1
(de)
|
2019-11-14 |
2022-09-21 |
Cohbar Inc. |
Cxcr4-antagonistenpeptide
|
EP4070113A4
(de)
|
2019-12-04 |
2023-12-20 |
Biora Therapeutics, Inc. |
Beurteilung von präeklampsie unter verwendung von tests für freien und dissoziierten plazentalen wachstumsfaktor
|
CA3166549A1
(en)
|
2020-01-03 |
2021-07-08 |
Incyte Corporation |
Combination therapy comprising a2a/a2b and pd-1/pd-l1 inhibitors
|
IL295093A
(en)
|
2020-01-30 |
2022-09-01 |
Ona Therapeutics S L |
Combined treatment for cancer and cancer metastases
|
EP4114445A1
(de)
|
2020-03-06 |
2023-01-11 |
Ona Therapeutics S.L. |
Anti-cd36-antikörper und ihre verwendung zur behandlung von krebs
|
CN115485302A
(zh)
|
2020-03-09 |
2022-12-16 |
百时美施贵宝公司 |
具有增强的激动剂活性的针对cd40的抗体
|
EP4132971A1
(de)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinitätsgereifte anti-lap-antikörper und verwendungen davon
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
IL298993A
(en)
|
2020-07-07 |
2023-02-01 |
BioNTech SE |
Therapeutic RNA for HPV positive cancer
|
WO2022036079A1
(en)
|
2020-08-13 |
2022-02-17 |
Bristol-Myers Squibb Company |
Methods of redirecting of il-2 to target cells of interest
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
JP2024502005A
(ja)
|
2020-12-29 |
2024-01-17 |
インサイト・コーポレイション |
A2a/a2b阻害剤、pd-1/pd-l1阻害剤、及び抗cd73抗体を含む併用療法
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
KR20240046323A
(ko)
|
2021-07-13 |
2024-04-08 |
비온테크 에스이 |
암에 대한 병용 요법에 있어서 cd40 및 cd137에 대한 다중특이 결합제
|
KR20240042476A
(ko)
|
2021-07-30 |
2024-04-02 |
오엔에이 테라퓨틱스 에스.엘. |
항-cd36 항체 및 암을 치료하기 위한 이의 용도
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
JP2024540106A
(ja)
|
2021-10-28 |
2024-10-31 |
ライエル・イミュノファーマ・インコーポレイテッド |
免疫細胞を培養するための方法
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
KR20240130705A
(ko)
|
2021-12-30 |
2024-08-29 |
네오이뮨텍, 인코퍼레이티드 |
Il-7 단백질 및 vegf 길항제의 조합으로 종양을 치료하는 방법
|
AU2023230110A1
(en)
|
2022-03-08 |
2024-10-24 |
Alentis Therapeutics Ag |
Use of anti-claudin-1 antibodies to increase t cell availability
|
WO2023192478A1
(en)
|
2022-04-01 |
2023-10-05 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
WO2024011109A2
(en)
*
|
2022-07-06 |
2024-01-11 |
Adverum Biotechnologies, Inc. |
Compositions and methods for treatment of achromotopsia
|
WO2024089418A1
(en)
|
2022-10-24 |
2024-05-02 |
Cancer Research Technology Limited |
Tumour sensitisation to checkpoint inhibitors with redox status modifier
|
WO2024089417A1
(en)
|
2022-10-24 |
2024-05-02 |
Memorial Sloan-Kettering Cancer Center |
Tumour stratification for responsiveness to an immune checkpoint inhibitor
|
WO2024102722A1
(en)
|
2022-11-07 |
2024-05-16 |
Neoimmunetech, Inc. |
Methods of treating a tumor with an unmethylated mgmt promoter
|
WO2024116140A1
(en)
|
2022-12-01 |
2024-06-06 |
Medimmune Limited |
Combination therapy for treatment of cancer comprising anti-pd-l1 and anti-cd73 antibodies
|
WO2024115725A1
(en)
|
2022-12-01 |
2024-06-06 |
BioNTech SE |
Multispecific antibody against cd40 and cd137 in combination therapy with anti-pd1 ab and chemotherapy
|
WO2024126457A1
(en)
|
2022-12-14 |
2024-06-20 |
Astellas Pharma Europe Bv |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and immune checkpoint inhibitors
|
WO2024150177A1
(en)
|
2023-01-11 |
2024-07-18 |
Advesya |
Treatment methods for solid tumors
|
WO2024150017A1
(en)
|
2023-01-13 |
2024-07-18 |
Akrivia Biomedics Limited |
Method of profiling diseases
|