ATE229516T1 - Benzofuran-4-carboxamide - Google Patents

Benzofuran-4-carboxamide

Info

Publication number: ATE229516T1
Authority: AT; Austria
Prior art keywords: benzofuran; carboxamide; substituted; optionally; flourine
Prior art date: 1996-08-19

Application number

AT97942858T

Other languages

English (en)

Inventor

Wolf-Ruediger Ulrich

Dieter Flockerzi

Beate Schmidt

Ulrich Thibaut

Armin Hatzelmann

Christian Schudt

Rolf Beume

Dietrich Haefner

Hans-Peter Kley

Hermann Amschler

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-19

Filing date

1997-08-13

Publication date

2002-12-15

1997-08-13 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2002-12-15 Application granted granted Critical

2002-12-15 Publication of ATE229516T1 publication Critical patent/ATE229516T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Furan Compounds (AREA)
Table Devices Or Equipment (AREA)

AT97942858T 1996-08-19 1997-08-13 Benzofuran-4-carboxamide ATE229516T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19633052		1996-08-19
PCT/EP1997/004398 WO1998007715A1 (de)	1996-08-19	1997-08-13	Novel benzofuran-4-carboxamides

Publications (1)

Publication Number	Publication Date
ATE229516T1 true ATE229516T1 (de)	2002-12-15

Family

ID=7802799

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97942858T ATE229516T1 (de)	1996-08-19	1997-08-13	Benzofuran-4-carboxamide

Country Status (11)

Country	Link
US (1)	US6211203B1 (de)
EP (1)	EP0923568B9 (de)
JP (1)	JP4309475B2 (de)
AT (1)	ATE229516T1 (de)
AU (1)	AU4454597A (de)
CY (1)	CY2458B1 (de)
DE (1)	DE69717827T2 (de)
DK (1)	DK0923568T5 (de)
ES (1)	ES2188983T4 (de)
PT (1)	PT923568E (de)
WO (1)	WO1998007715A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP0100042A3 (en) *	1996-05-20	2003-01-28	Darwin Discovery Ltd Cambridge	Benzofuran carboxamides medicaments containing the same and their therapeutic use
JP2002502851A (ja) *	1998-02-09	2002-01-29	ダーウィン・ディスカバリー・リミテッド	ベンゾフラン−４−カルボキサミドとその治療的使用
TW555759B (en) *	1998-06-08	2003-10-01	Darwin Discovery Ltd	Heterocyclic compounds and their therapeutic use
WO1999064414A1 (de) *	1998-06-10	1999-12-16	Byk Gulden Lomberg Chemische Fabrik Gmbh	Benzamide mit tetrahydrofuranyloxy-substituenten als inhibitoren der phosphodiesterase 4
JP2002529444A (ja) *	1998-11-12	2002-09-10	アリアド・ファーマシューティカルズ・インコーポレイテッド	二環式シグナル伝達阻害剤、それを含む組成物とその用途
DE19924340A1 (de)	1999-05-27	2000-11-30	Basf Ag	Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
SI1212089T1 (sl)	1999-08-21	2006-08-31	Altana Pharma Ag	Sinergisticna kombinacija roflumilasta in salmeterola
GB0003257D0 (en)	2000-02-11	2000-04-05	Darwin Discovery Ltd	Heterocyclic compounds and their therapeutic use
EP2258359A3 (de)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
EP2275095A3 (de)	2005-08-26	2011-08-17	Braincells, Inc.	Neurogenese durch modulation des Muscarinrezeptors
US7985756B2 (en)	2005-10-21	2011-07-26	Braincells Inc.	Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
US7842713B2 (en) *	2006-04-20	2010-11-30	Pfizer Inc	Fused phenyl amido heterocyclic compounds
WO2007134077A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
CA2651813A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
JP2010502722A (ja)	2006-09-08	2010-01-28	ブレインセルス，インコーポレイティド	４−アシルアミノピリジン誘導体を含む組み合わせ
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
PE20110303A1 (es)	2008-09-11	2011-05-21	Pfizer	Derivados de heteroaril acetamidas como activadores de glucoquinasa
AR074760A1 (es) *	2008-12-18	2011-02-09	Metabolex Inc	Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
US20100216805A1 (en)	2009-02-25	2010-08-26	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
NZ595024A (en) *	2009-03-11	2013-01-25	Pfizer	Benzofuranyl derivatives used as glucokinase inhibitors
RU2446143C2 (ru) *	2010-05-19	2012-03-27	Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ)	Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
US8299117B2 (en)	2010-06-16	2012-10-30	Metabolex Inc.	GPR120 receptor agonists and uses thereof
EP2582674B1 (de) *	2010-06-16	2014-10-01	Cymabay Therapeutics, Inc.	Gpr120-rezeptoragonisten und ihre verwendung
EP2804603A1 (de)	2012-01-10	2014-11-26	President and Fellows of Harvard College	Betazellen-replikation für promoterverbindungen und verwendungsverfahren dafür
US11390614B2 (en)	2017-11-10	2022-07-19	Jiangsu Hengrui Medicine Co., Ltd.	Method for preparing benzofuran derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3093271B2 (ja) *	1993-07-02	2000-10-03	ビイクグルデンロンベルクヒェーミッシェファブリークゲゼルシャフトミットベシュレンクテルハフツング	フルオルアルコキシ置換のベンズアミド及び環状ヌクレオチドホスホジエステラーゼ阻害剤としてのその使用
SK281857B6 (sk) *	1994-07-22	2001-08-06	Byk Gulden Lomberg Chemische Fabrik Gmbh	Dihydrobenzofurány, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
JP4172817B2 (ja) *	1995-05-19	2008-10-29	協和醗酵工業株式会社	含酸素複素環化合物
US5773467A (en) *	1995-12-05	1998-06-30	Chiroscience, Ltd.	Benzofuran sulphonanmides
HUP0100042A3 (en) *	1996-05-20	2003-01-28	Darwin Discovery Ltd Cambridge	Benzofuran carboxamides medicaments containing the same and their therapeutic use

1997
- 1997-08-13 DE DE69717827T patent/DE69717827T2/de not_active Expired - Lifetime
- 1997-08-13 DK DK97942858T patent/DK0923568T5/da active
- 1997-08-13 AU AU44545/97A patent/AU4454597A/en not_active Abandoned
- 1997-08-13 JP JP51035698A patent/JP4309475B2/ja not_active Expired - Fee Related
- 1997-08-13 US US09/147,640 patent/US6211203B1/en not_active Expired - Lifetime
- 1997-08-13 WO PCT/EP1997/004398 patent/WO1998007715A1/de active Search and Examination
- 1997-08-13 EP EP97942858A patent/EP0923568B9/de not_active Expired - Lifetime
- 1997-08-13 PT PT97942858T patent/PT923568E/pt unknown
- 1997-08-13 AT AT97942858T patent/ATE229516T1/de not_active IP Right Cessation
- 1997-08-13 ES ES97942858T patent/ES2188983T4/es not_active Expired - Lifetime
2004
- 2004-06-08 CY CY0400046A patent/CY2458B1/xx unknown

Also Published As

Publication number	Publication date
DK0923568T5 (da)	2003-11-03
WO1998007715A1 (de)	1998-02-26
ES2188983T3 (es)	2003-07-01
EP0923568B1 (de)	2002-12-11
JP2000516932A (ja)	2000-12-19
CY2458B1 (en)	2005-06-03
ES2188983T4 (es)	2004-06-01
EP0923568A1 (de)	1999-06-23
JP4309475B2 (ja)	2009-08-05
DE69717827T2 (de)	2003-09-04
EP0923568B9 (de)	2003-08-13
DK0923568T3 (da)	2003-04-07
US6211203B1 (en)	2001-04-03
AU4454597A (en)	1998-03-06
PT923568E (pt)	2003-04-30
DE69717827D1 (de)	2003-01-23
WO1998007715A9 (de)	1999-04-29

Publication	Publication Date	Title
ATE229516T1 (de)	2002-12-15	Benzofuran-4-carboxamide
EA199700061A1 (ru)	1997-12-30	Способ получения силденафила
DE69618231D1 (de)	2002-01-31	TETRAHYDROIMIDAZOPYRIDOINDOLDIONE ALS cGMP SPEZIFISCHE PDE HEMMER
ES2193252T3 (es)	2003-11-01	Quinolonas y su uso terapeutico.
ATE260103T1 (de)	2004-03-15	Ortho-anthranilamide derivate als antikoagulantien
ATE215371T1 (de)	2002-04-15	Naphthyl substituierte benzimidazolderivate als antikoagulantien
IT8919316A0 (it)	1989-02-06	Benzoderivati di composti eterociclici contenenti azoto.
DE69722656D1 (de)	2003-07-10	Bicyclische arylcarboxamide und ihre therapeutische verwendung
DE59100597D1 (de)	1993-12-23	Verwendung von N-Alkyl-lactamen als Kristallisationsinhibitoren.
EP0932606A4 (de)	2000-01-19	Prenyl-transferase inhibitoren
ATE233252T1 (de)	2003-03-15	Substituierte dihydrobenzofurane als pde- hemmstoffe
ES2122258T3 (es)	1998-12-16	4-azaesteroides 15 sustituidos.
EA200200381A1 (ru)	2002-10-31	Тетрагидротиопиранфталазиноновые производные в качестве ингибиторов pde4
DE69632936D1 (de)	2004-08-26	Verwendung von Pyrrolverbindungen als Antifouling-Wirkstoff
ES2179254T3 (es)	2003-01-16	1-poliarilpirazoles plaguicidas.
DK0696278T3 (da)	1999-04-26	Herbicidtvirkende substituerede 1-phenyl- eller 1-pyridinylbenzotriazoler
NZ333854A (en)	2000-12-22	Intermediates for the preparation of 2-imidazoline-5-ones
DE59711147D1 (de)	2004-01-29	Neue Imidazo- und Oxazolopyridine als Phosphodiesterase Inhibitoren.
DE69025817D1 (de)	1996-04-18	3-Keto-HMG-CoA Reduktase-Inhibitoren
ES2173634T3 (es)	2002-10-16	Compuestos heterociclicos que presentan actividad inhibidora de mmp y tnf.
UY24326A1 (es)	2000-12-29	Nuevas piperidinas.
GR1001386B (el)	1993-10-29	Ετεροκυκλικές ενώσεις.
SU1746666A1 (ru)	1999-06-10	Замещенные 3-аминометиленпирролидин-2,4-дионы, обладающие противосудорожной активностью
SE9201524D0 (sv)	1992-05-14	Haalsaag/dosfraes, med automatisk urkast av borkaernan
SU1690242A1 (ru)	1999-08-10	Антифидант

Legal Events

Date	Code	Title	Description
2003-05-15	UEP	Publication of translation of european patent specification	Ref document number: 0923568 Country of ref document: EP
2010-05-15	REN	Ceased due to non-payment of the annual fee

Date

Code

Title

Description

2003-05-15

UEP

Publication of translation of european patent specification

Ref document number: 0923568

Country of ref document: EP

2010-05-15

REN

Ceased due to non-payment of the annual fee