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ATE224748T1 - Inhalationsvorrichtung für trockenpulver - Google Patents

Inhalationsvorrichtung für trockenpulver

Info

Publication number
ATE224748T1
ATE224748T1 AT95202927T AT95202927T ATE224748T1 AT E224748 T1 ATE224748 T1 AT E224748T1 AT 95202927 T AT95202927 T AT 95202927T AT 95202927 T AT95202927 T AT 95202927T AT E224748 T1 ATE224748 T1 AT E224748T1
Authority
AT
Austria
Prior art keywords
patient
inhalation device
aerosolisation
dry powder
deagglomeration
Prior art date
Application number
AT95202927T
Other languages
English (en)
Inventor
Peter D Hodson
David K Smith
Anthony C L Wass
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898909891A external-priority patent/GB8909891D0/en
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Application granted granted Critical
Publication of ATE224748T1 publication Critical patent/ATE224748T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0018Details of inhalators; Constructional features thereof with exhalation check valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0025Mouthpieces therefor with caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043Non-destructive separation of the package, e.g. peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0053Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
    • A61M15/0055Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being coiled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0093Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007Mechanical counters
    • A61M15/0071Mechanical counters having a display or indicator
    • A61M15/0078Mechanical counters having a display or indicator on a strip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/02Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0024Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with an on-off output signal, e.g. from a switch
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT95202927T 1989-04-28 1990-04-30 Inhalationsvorrichtung für trockenpulver ATE224748T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898909891A GB8909891D0 (en) 1989-04-28 1989-04-28 Device
GB909000261A GB9000261D0 (en) 1989-04-28 1990-01-05 Device

Publications (1)

Publication Number Publication Date
ATE224748T1 true ATE224748T1 (de) 2002-10-15

Family

ID=26295297

Family Applications (2)

Application Number Title Priority Date Filing Date
AT95202927T ATE224748T1 (de) 1989-04-28 1990-04-30 Inhalationsvorrichtung für trockenpulver
AT90907220T ATE138814T1 (de) 1989-04-28 1990-04-30 Inhalationsvorrichtung für trockenpulver

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT90907220T ATE138814T1 (de) 1989-04-28 1990-04-30 Inhalationsvorrichtung für trockenpulver

Country Status (10)

Country Link
US (2) US5655523A (de)
EP (2) EP0705614B1 (de)
JP (1) JPH05501505A (de)
AT (2) ATE224748T1 (de)
AU (1) AU643435B2 (de)
CA (1) CA2058764A1 (de)
DE (2) DE69027319T2 (de)
DK (1) DK0470154T3 (de)
ES (1) ES2087911T3 (de)
WO (1) WO1990013327A1 (de)

Families Citing this family (278)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8909891D0 (en) * 1989-04-28 1989-06-14 Riker Laboratories Inc Device
ATE224748T1 (de) * 1989-04-28 2002-10-15 Riker Laboratories Inc Inhalationsvorrichtung für trockenpulver
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
SK280968B6 (sk) * 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
JP3307389B2 (ja) * 1990-06-28 2002-07-24 ベーリンガー インゲルハイム コマンディトゲゼルシャフト 粉末投与のための方法、装置及び担体
GB9016789D0 (en) * 1990-07-31 1990-09-12 Lilly Industries Ltd Medicament administering devices
GB9027255D0 (en) * 1990-12-17 1991-02-06 Minnesota Mining & Mfg Closure system for inhalers
FR2676929B1 (fr) * 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse Inhalateur de poudres.
WO1993000123A1 (en) * 1991-06-26 1993-01-07 Schering Corporation Inhalation device for powdered medicaments
HUT64242A (en) * 1991-08-15 1993-12-28 Bon Del Inhalator and method for inhaling
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
US5469843A (en) * 1991-11-12 1995-11-28 Minnesota Mining And Manufacturing Company Inhalation device
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
GB2273660B (en) * 1992-09-11 1996-07-17 Aid Medic Ltd Drug delivery arrangement
SK51695A3 (en) * 1992-10-19 1995-11-08 Dura Pharma Inc Dry powder medicament inhaler
SE9203570D0 (sv) * 1992-11-27 1992-11-27 Astra Ab Inhaler for multiple use
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US5441060A (en) * 1993-02-08 1995-08-15 Duke University Dry powder delivery system
EP0692990B1 (de) * 1993-04-06 1998-09-23 Minnesota Mining And Manufacturing Company Vorrichtung zum deagglomerieren für trockenpulverinhalatoren
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
GB9314614D0 (en) * 1993-07-14 1993-08-25 Minnesota Mining & Mfg Dry powder inhalers
GB9324391D0 (en) * 1993-11-26 1994-01-12 Minnesota Mining & Mfg Device for transmission of one-way torque
GB9326574D0 (en) * 1993-12-31 1994-03-02 King S College London Dry power inhalers
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
ES2316917T3 (es) * 1994-03-07 2009-04-16 Nektar Therapeutics Metodos y composiciones para suministro pulmonar de insulina.
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5647347A (en) * 1994-10-21 1997-07-15 Glaxo Wellcome Inc. Medicament carrier for dry powder inhalator
JP3308425B2 (ja) * 1995-03-10 2002-07-29 株式会社ユニシアジェックス 鼻腔用投薬器
SE9502800D0 (sv) * 1995-08-10 1995-08-10 Astra Ab Disposable inhaler
US6026809A (en) * 1996-01-25 2000-02-22 Microdose Technologies, Inc. Inhalation device
US5694920A (en) * 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
US5944012A (en) * 1996-03-25 1999-08-31 Pera; Ivo E. Method for dispensing antioxidant vitamins by inhalation background of the invention
IL126701A (en) * 1996-04-29 2001-08-08 Dura Pharma Inc Inhaler system for inhalation of a dry powder drug
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
GB2320489A (en) * 1996-12-20 1998-06-24 Norton Healthcare Ltd Inhaler dose counter
WO1998029110A2 (en) 1996-12-30 1998-07-09 Battelle Memorial Institute Formulation and method for treating neoplasms by inhalation
SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
SE9700937D0 (sv) 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
SE9700936D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
US5881720A (en) * 1997-04-29 1999-03-16 The Procter & Gamble Company Method of delivering halotherapy
NL1006058C2 (nl) * 1997-05-14 1998-11-17 R & D Injector Ag Doseerinrichting.
ZA989744B (en) * 1997-10-31 2000-04-26 Lilly Co Eli Method for administering acylated insulin.
FI105074B (fi) 1997-12-31 2000-06-15 Leiras Oy Farmaseuttisen formulaation valmistusmenetelmä
PL343276A1 (en) 1998-03-16 2001-08-13 Inhale Therapeutic Syst Aerosolized active agent delivery
US6152130A (en) * 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
US6142146A (en) * 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
NZ508663A (en) * 1998-06-12 2003-02-28 Microdose Technologies Inc A dry powder inhaler with a vibrator to deaggregate the powder and feedback control for controlling dosing
SE512386C2 (sv) * 1998-07-30 2000-03-06 Microdrug Ag Förfarande och anordning för klassificering av elektrostatiskt laddat pulverformigt material
SE512433C2 (sv) * 1998-07-30 2000-03-13 Microdrug Ag Förfarande för finfördelning och elektrostatisk uppladdning av ett pulver avsett för administrering främst genom inhalation jämte anordning för matning, finfördelning och elektrostatisk uppladdning av ett pulver avsett för administrering främst genom inhalation
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
GB9825118D0 (en) * 1998-11-16 1999-01-13 Minnesota Mining & Mfg Breath-actuated aerosol dispensers
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US6752148B1 (en) * 1999-02-10 2004-06-22 Delsys Pharmaceutical Company Medicament dry powder inhaler dispensing device
EP2340865B1 (de) * 1999-03-03 2016-07-20 Optinose AS Nasales Verabreichungsgerät
AU3158700A (en) * 1999-03-12 2000-10-04 Glaxo Group Limited Metering valve
US6223744B1 (en) 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
US6923979B2 (en) * 1999-04-27 2005-08-02 Microdose Technologies, Inc. Method for depositing particles onto a substrate using an alternating electric field
SE516826C2 (sv) * 1999-06-18 2002-03-05 Shl Medical Ab Anordning i en inhalator med organ för aktivering och avaktivering av en kanister som svar på ett luftflöde
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US6428809B1 (en) 1999-08-18 2002-08-06 Microdose Technologies, Inc. Metering and packaging of controlled release medication
SE517806C2 (sv) * 1999-11-11 2002-07-16 Microdrug Ag Doseringsanordning för inhalator
DE19956260A1 (de) * 1999-11-23 2001-05-31 Inamed Gmbh Abscheidevorrichtung, insbesondere für Trockenpulvermedikamente in Aerosolform
EP1235606A1 (de) * 1999-12-11 2002-09-04 Glaxo Group Limited Medikamentspender
AR026914A1 (es) * 1999-12-11 2003-03-05 Glaxo Group Ltd Distribuidor de medicamento
GB9929486D0 (en) 1999-12-15 2000-02-09 Glaxo Group Ltd Inhalation delivery apparatus and method
US7080642B2 (en) * 1999-12-22 2006-07-25 3M Innovative Properties Company Refillable device with counting means
GB0003197D0 (en) * 2000-02-11 2000-04-05 Aid Medic Ltd Improvements in and relating to controlling drug delivery
US6971383B2 (en) * 2001-01-24 2005-12-06 University Of North Carolina At Chapel Hill Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods
FI20000810A0 (fi) * 2000-04-06 2000-04-06 Orion Yhtymae Oyj Jauheinhalaattori
US6748944B1 (en) * 2000-05-03 2004-06-15 Dellavecchia Michael Anthony Ultrasonic dosage device and method
AU2001263098A1 (en) 2000-05-12 2001-11-26 Iep Pharmaceutical Devices, Inc. Powder/liquid metering valve
GB0015034D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Inhalation device
CA2640679C (en) * 2000-07-24 2012-03-27 Clinical Designs Limited Dispenser with breath actuatable valve
DE10040528A1 (de) * 2000-08-18 2002-02-28 Pari Gmbh Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke
AUPR020400A0 (en) * 2000-09-19 2000-10-12 Glaxo Wellcome Australia Ltd Inhalation device
SE517225C2 (sv) * 2000-09-21 2002-05-14 Microdrug Ag Optimering av en elektrostatiskt doserad inhalator för torrt pulver
SE517228C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med andningsaktivering
SE517229C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Kontinuerlig inhalator för torrt pulver
JP2004512101A (ja) * 2000-10-20 2004-04-22 グラクソ グループ リミテッド 吸入器
GB0025749D0 (en) * 2000-10-20 2000-12-06 Glaxo Group Ltd Inhaler
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
US20100310477A1 (en) * 2000-11-28 2010-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Pharmaceutical compositions based on anticholingerics and additional active ingredients
EP2283817B1 (de) 2000-11-30 2016-05-18 Vectura Limited Herstellungsverfahren für Partikel zur Verwendung in einer Arrzneizusammensetzung
WO2002043700A2 (en) * 2000-11-30 2002-06-06 Vectura Limited Particles for use in a pharmaceutical composition
US8122880B2 (en) * 2000-12-18 2012-02-28 Palo Alto Research Center Incorporated Inhaler that uses focused acoustic waves to deliver a pharmaceutical product
ZA200306564B (en) * 2001-02-26 2004-10-15 Optinose As Nasal devices.
DE60101451T2 (de) 2001-03-05 2004-10-21 Pera Ivo E Inhaliergerät zur Verteilung von in einer Kapsel enthaltenen Medikamenten in Pulverform durch die Atemwege
US7025058B2 (en) 2001-04-26 2006-04-11 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
WO2002089879A1 (en) * 2001-05-10 2002-11-14 Vectura Delivery Devices Limited Inhalers
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US6805853B2 (en) 2001-11-09 2004-10-19 Alexza Molecular Delivery Corporation Delivery of diazepam through an inhalation route
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
ES2316571T3 (es) 2001-05-24 2009-04-16 Alexza Pharmaceuticals, Inc. Administracion de alprazolam, estazolam, midazolam o triazolam a traves de una via inhalatoria.
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
EP1392262A1 (de) * 2001-05-24 2004-03-03 Alexza Molecular Delivery Corporation Verabreichung von arzneimittel-estern durch inhalation
US20070087048A1 (en) * 2001-05-31 2007-04-19 Abrams Andrew L Oral dosage combination pharmaceutical packaging
US20020189615A1 (en) * 2001-06-13 2002-12-19 Henry Adam S. Inhaler with dose control
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
GB0204328D0 (en) * 2002-02-25 2002-04-10 Fyne Dynamics Ltd Flow indicator
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
BR0303652A (pt) 2002-03-22 2004-07-13 Clinical Designs Ltd Acessório de lata
SE524957C2 (sv) * 2002-04-12 2004-11-02 Microdrug Ag Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament
SE524990C2 (sv) 2002-04-12 2004-11-09 Microdrug Ag Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver
SE525027C2 (sv) * 2002-04-12 2004-11-16 Microdrug Ag Anordning utgörande en pulverlufthyvel
ATE310514T1 (de) * 2002-04-19 2005-12-15 Yissum Res Dev Co Beta-agonisten-verbindungen mit stickoxid- donatoren-gruppen und reaktionsfähige sauerstoffspezies-fängergruppen und ihre verwendung bei der behandlung von atemwegsstörungen
GB0209526D0 (en) * 2002-04-26 2002-06-05 Glaxo Group Ltd Medicament dispenser
GB0209528D0 (en) * 2002-04-26 2002-06-05 Glaxo Group Ltd Medicament dispenser
US6889690B2 (en) 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US6985798B2 (en) 2002-05-10 2006-01-10 Oriel Therapeutics, Inc. Dry powder dose filling systems and related methods
US7118010B2 (en) * 2002-05-10 2006-10-10 Oriel Therapeutics, Inc. Apparatus, systems and related methods for dispensing and /or evaluating dry powders
US7677411B2 (en) * 2002-05-10 2010-03-16 Oriel Therapeutics, Inc. Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
CA2531055C (en) * 2002-06-27 2011-12-06 Oriel Therapeutics, Inc. Dry powder dose filling systems and related methods
EP3308772B8 (de) * 2002-06-28 2021-03-17 Civitas Therapeutics, Inc. Epinephrin zur inhalation
WO2004037843A2 (en) * 2002-10-25 2004-05-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
AU2002952683A0 (en) * 2002-11-15 2002-11-28 Commonwealth Scientific And Industrial Research Organisation Apparatus for delivering dry aerosols to the respiratory tract
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
GB0304000D0 (en) * 2003-02-21 2003-03-26 Clinical Designs Ltd Dispenser
JP2004290592A (ja) * 2003-03-28 2004-10-21 Canon Inc 液滴吐出装置
GB0311570D0 (en) * 2003-05-20 2003-06-25 Optinose As Delivery device and method
US20050079166A1 (en) 2003-05-21 2005-04-14 Alexza Molecular Delivery Corporation Self-contained heating unit and drug-supply unit employing same
JP4739207B2 (ja) 2003-08-29 2011-08-03 ダイアックス コーポレーション ポリペグ化されたプロテアーゼインヒビター
WO2005025506A2 (en) * 2003-09-10 2005-03-24 Map Pharmaceuticals, Inc. Aerosol formulations for delivery of dihydroergotamine to the systemic circulation via pulmonary inhalation
ES2289221T3 (es) * 2003-10-06 2008-02-01 BANG & OLUFSEN MEDICOM A/S Inhalador.
US7451761B2 (en) * 2003-10-27 2008-11-18 Oriel Therapeutics, Inc. Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
WO2005041848A2 (en) 2003-10-27 2005-05-12 Oriel Therapeutics, Inc. Dry powder drug containment system packages with tabs, inhalers and associated methods
GB0327112D0 (en) * 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0328859D0 (en) 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
US7607435B2 (en) * 2004-01-21 2009-10-27 Battelle Memorial Institute Gas or liquid flow sensor
GB2410192B (en) * 2004-01-23 2005-12-07 Eg Technology Ltd An inhaler
US7624733B2 (en) * 2004-02-09 2009-12-01 Oriel Therapeutics, Inc. Inhalers with extendable/retractable forward member and associated methods of dispensing inhalant substances
AU2005244942A1 (en) * 2004-05-19 2005-12-01 Wyeth Modulation of immunoglobulin production and atopic disorders
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
CN100569310C (zh) * 2004-08-02 2009-12-16 佳能株式会社 吸入设备
KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
ES2540886T3 (es) 2004-08-23 2015-07-14 Mannkind Corporation Sales de dicetopiperazina para la administración de fármacos
WO2006031712A2 (en) * 2004-09-13 2006-03-23 Oriel Therapeutics, Inc. Tubular dry powder drug containment systems, associated inhalers and methods
WO2006031775A2 (en) * 2004-09-13 2006-03-23 Oriel Therapeutics, Inc. Dry powder inhalers that inhibit agglomeration, related devices and methods
GB0425758D0 (en) 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
GB0507100D0 (en) * 2005-04-08 2005-05-11 Team Holdings Uk Ltd Improvements in or relating to inhalers
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
PT2594272T (pt) 2005-05-18 2018-07-31 Horizon Orphan Llc Fluoroquinolonas aerossolizadas e suas utilizações
IL175664A0 (en) * 2006-05-16 2006-09-05 Aespira Ltd Dry-powder inhaler
PT1915397E (pt) * 2005-08-19 2015-04-30 Univ Pennsylvania Anticorpos antagonistas contra gdf-8 e utilizações no tratamento de ela e outros distúrbios associados a gdf-8
EP1934805A4 (de) * 2005-08-25 2017-01-11 Oriel Therapeutics, Inc. Medikamentenbehältersysteme mit sticks, diesbezügliche kits, trockenpulver-inhalierer und verfahren
CN104324366B (zh) 2005-09-14 2016-10-05 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
WO2007053878A1 (en) 2005-11-08 2007-05-18 Resmed Ltd Nasal assembly
US7832397B2 (en) 2005-12-28 2010-11-16 Philip Morris Usa Inc. Aerosol powder delivery device
US7987845B2 (en) 2006-01-31 2011-08-02 Oriel Therapeutics, Inc. Dry powder inhalers having spiral travel paths, unit dose microcartridges with dry powder, related devices and methods
GB0602980D0 (en) * 2006-02-14 2006-03-29 Optinose As Delivery device and method
CA2642745A1 (en) * 2006-02-20 2007-08-30 Boehringer Ingelheim International Gmbh Inhaler
GB2433207B (en) * 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
ES2647080T3 (es) 2006-02-22 2017-12-19 Mannkind Corporation Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo
CA2642229C (en) 2006-02-24 2015-05-12 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the jak pathway
US8127763B2 (en) * 2006-03-03 2012-03-06 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
GB0605723D0 (en) 2006-03-23 2006-05-03 3M Innovative Properties Co Powder filling processes
PT2001537E (pt) * 2006-04-05 2011-05-11 Microdose Therapeutx Inc Dispositivo de inala??o com doseamento vari?vel
WO2008008281A2 (en) 2006-07-07 2008-01-17 Proteus Biomedical, Inc. Smart parenteral administration system
FR2904229B1 (fr) * 2006-07-25 2008-10-10 Valois Sas Dispositif de distribution de produit fluide.
FR2904228B1 (fr) * 2006-07-25 2009-05-29 Valois Sas Dispositif de distribution de produit fluide.
DE102006044755A1 (de) * 2006-09-20 2008-04-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102006044756A1 (de) * 2006-09-20 2008-04-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
EP2086618A2 (de) * 2006-11-19 2009-08-12 Aespira Ltd. Trockenpulverinhalator
FR2909643B1 (fr) * 2006-12-11 2011-03-04 Valois Sas Dispositif de distribution de produit fluide
PL2425820T3 (pl) * 2007-02-11 2015-08-31 Map Pharmaceuticals Inc Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych
EP2121088B1 (de) 2007-03-09 2016-07-13 Alexza Pharmaceuticals, Inc. Erhitzungseinheit zur verwendung in einer arzneimittelabgabevorrichtung
US11224704B2 (en) * 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
EP2011535A1 (de) * 2007-07-06 2009-01-07 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalator
US8261738B2 (en) * 2007-07-24 2012-09-11 Respironics Respiratory Drug Delivery (Uk) Ltd. Apparatus and method for maintaining consistency for aerosol drug delivery treatments
US20090087483A1 (en) * 2007-09-27 2009-04-02 Sison Raymundo A Oral dosage combination pharmaceutical packaging
WO2009046215A2 (en) * 2007-10-02 2009-04-09 Lab International Srl Safety and abuse deterrent improved device
US8439033B2 (en) 2007-10-09 2013-05-14 Microdose Therapeutx, Inc. Inhalation device
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
PE20091163A1 (es) 2007-11-01 2009-08-09 Wyeth Corp Anticuerpos para gdf8
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
PT2230934E (pt) 2007-12-14 2012-11-20 Aerodesigns Inc Distribuir produtos alimentares aerossolizáveis
SG10201610381XA (en) * 2008-03-27 2017-01-27 Mannkind Corp A dry powder inhalation system
FR2930164B1 (fr) * 2008-04-16 2011-10-07 Valois Sas Dispositif de distribution de produit fluide.
IL191190A0 (en) * 2008-05-01 2009-08-03 Dan Adler Dry powder inhaler
DK2293833T3 (en) 2008-06-13 2016-05-23 Mannkind Corp DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
WO2010019656A1 (en) * 2008-08-12 2010-02-18 Wyeth Humanized anti-rage antibody
CN102325532B (zh) 2008-10-07 2015-06-17 Mpex医药有限公司 用于减轻肺部炎症的左氧氟沙星吸入剂
NZ607408A (en) 2008-10-07 2014-10-31 Mpex Pharmaceuticals Inc Aerosol fluoroquinolone formulations for improved pharmacokinetics
GB201020130D0 (en) * 2010-11-26 2011-01-12 Vectura Delivery Devices Ltd Inhaler
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US10387621B2 (en) 2009-01-16 2019-08-20 Cerner Innovation, Inc. Matching of vibratory inhalers to patient vocal tract for optimization of particle dispersion
PE20110924A1 (es) 2009-01-23 2011-12-24 Rigel Pharmaceuticals Inc Derivados de 2, 4-diamino-pirimidina n2, n4-disustituidos como inhibidores de jak3
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
US9125999B2 (en) 2009-05-18 2015-09-08 Adamis Pharmaceuticals Corporation Dry powder inhaler dose counters
EP2432535B1 (de) * 2009-05-18 2017-09-20 Adamis Pharmaceuticals Corporation Trockenpulverinhalatoren
SG176738A1 (en) 2009-06-12 2012-01-30 Mannkind Corp Diketopiperazine microparticles with defined specific surface areas
WO2010151804A1 (en) * 2009-06-26 2010-12-29 Map Pharmaceuticals, Inc. Administration of dihydroergotamine mesylate particles using a metered dose inhaler
EP2470167A4 (de) 2009-08-27 2013-08-14 Stc Unm Verfahren und system zur dosierung und beschichtung von inhalationspulvern auf trägerpartikel
WO2011029059A1 (en) 2009-09-04 2011-03-10 Mpex Pharmaceuticals, Inc. Use of aerosolized levofloxacin for treating cystic fibrosis
EP2496295A1 (de) 2009-11-03 2012-09-12 MannKind Corporation Vorrichtung und verfahren zur simulation von einatmungsanstrengungen
AU2010319328A1 (en) 2009-11-12 2012-05-31 Stc.Unm Dry powder inhaler with flutter dispersion member
DK2515977T3 (en) 2009-12-26 2018-04-16 Inspiro Medical Ltd DEVICE FOR DELIVERY OF DRY POWDER
EP2521584B1 (de) 2010-01-05 2018-10-17 MicroDose Therapeutx, Inc. Inhalationsvorrichtung
EP2528601A1 (de) 2010-01-26 2012-12-05 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Zusammensetzungen und verfahren zur prävention und behandlung von lungenhochdruck
BR112012019212A2 (pt) 2010-02-01 2017-06-13 Proteus Digital Health Inc sistema de coleta de dados
MY169700A (en) 2010-02-01 2019-05-13 Proteus Digital Health Inc Data gathering system
JP2013529124A (ja) * 2010-03-09 2013-07-18 エスティーシー. ユーエヌエム 表面を微小粒子でドライコーティングする装置および方法
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
FR2962343B1 (fr) * 2010-07-07 2012-08-03 Valois Sas Inhalateur de poudre seche.
ES2646748T3 (es) 2010-12-07 2017-12-15 Respira Therapeutics, Inc. Inhalador de polvo seco
EP2670242B1 (de) 2011-01-31 2022-03-16 Avalyn Pharma Inc. Aerosolförmige pirfenidon- und pyridonanalogverbindungen und verwendungen davon
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
US8834411B2 (en) * 2011-04-06 2014-09-16 Mystic Pharmaceuticals, Inc. Medical devices for dispensing powders
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
US8877967B2 (en) 2012-03-23 2014-11-04 Oxigene, Inc. Compositions and methods for inhibition of cathepsins
NZ702269A (en) 2012-06-15 2017-07-28 Pfizer Improved antagonist antibodies against gdf-8 and uses therefor
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送系统和方法
MX354365B (es) 2012-07-19 2018-02-28 Adamis Pharmaceuticals Corp Aparato alimentador de polvo.
US10058530B2 (en) 2012-10-25 2018-08-28 The General Hospital Corporation Combination therapies for the treatment of Alzheimer's disease and related disorders
CA2889446C (en) 2012-10-25 2021-05-11 The General Hospital Corporation Combination therapies for the treatment of alzheimer's disease and related disorders
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
US10421729B2 (en) 2013-03-15 2019-09-24 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX2015016102A (es) * 2013-05-23 2016-08-08 Aztherapies Inc Metodos para la liberacion de cromolina.
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
WO2015017728A1 (en) 2013-07-31 2015-02-05 Windward Pharma, Inc. Aerosol tyrosine kinase inhibitor compounds and uses thereof
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
WO2015034709A1 (en) 2013-09-04 2015-03-12 3M Innovative Properties Company Dry-powder inhaler and method
CA2928028A1 (en) 2013-10-22 2015-04-30 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
CA2936330C (en) 2014-01-10 2023-01-03 Genoa Pharmaceuticals Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
NO2709641T3 (de) 2014-03-10 2018-05-12
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
CN106714880B (zh) 2014-08-28 2021-12-03 诺顿(沃特福特)有限公司 呼吸驱动吸入器的依从性监控模块
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
DE102014116694A1 (de) 2014-11-14 2016-05-19 Bluestone Technology GmbH Verfahren und Vorrichtung zur kontrollierten Abgabe von Partikeln
EP3244952A4 (de) 2015-01-14 2018-11-14 Respira Therapeutics, Inc. Pulverdispersionsverfahren und -vorrichtungen
CN106031809A (zh) * 2015-03-12 2016-10-19 昆山科技大学 药雾吸入辅助器结构
US10986819B2 (en) * 2015-06-14 2021-04-27 Tobe Influence Innovation Ltd. Apparatus for disinfestation of beehives and method for controlling same
TR201900331T4 (tr) * 2015-06-29 2019-02-21 Philip Morris Products Sa Bir aerosol - üretici sistem için kartuş.
ES2745552T3 (es) 2015-07-20 2020-03-02 Pearl Therapeutics Inc Sistemas de administración de aerosol
US10688260B2 (en) 2015-09-24 2020-06-23 Mystic Pharmaceuticals, Inc. Devices and systems for air assisted dry powder administration
WO2017079397A1 (en) * 2015-11-05 2017-05-11 Otitopic Inc. Dry powder inhalation device
EP3432955B1 (de) * 2016-03-24 2021-01-27 Trudell Medical International Beatmungssystem mit elektronischem indikator
JP2019516485A (ja) 2016-05-19 2019-06-20 マンカインド コーポレイション 吸入を検出および監視するための機器、システム、および方法
CN109922800B (zh) 2016-08-31 2023-06-13 通用医疗公司 与神经退行性疾病相关的神经炎症中的巨噬细胞/小胶质细胞
CN109045428B (zh) * 2016-10-03 2021-06-29 捷普科技(上海)有限公司 药剂分配器
GB201706505D0 (en) 2017-04-25 2017-06-07 3M Innovative Properties Co Medicinal inhaler drive mechanism
KR20200010391A (ko) * 2017-05-26 2020-01-30 마이크로도스 테라퍼스, 인코포레이티드 합성 분사를 이용하는 흡입기
CN107233659B (zh) * 2017-05-31 2020-05-19 麦递途医疗科技(上海)有限公司 一种占位给药装置
US11452825B2 (en) 2017-05-31 2022-09-27 Philip Morris Products S.A. Inhaler article with occluded airflow element
WO2019017995A1 (en) 2017-07-20 2019-01-24 Aztherapies, Inc. FORMULATIONS OF CROMOLYNE SODIUM POWDER AND IBUPROFEN
WO2020010049A1 (en) 2018-07-02 2020-01-09 The General Hospital Corporation POWDERED FORMULATIONS OF CROMOLYN SODIUM AND α-LACTOSE
US20220000880A1 (en) 2018-11-01 2022-01-06 Rigel Pharmaceuticals, Inc. Method and composition embodiments for treating acute myeloid leukemia
WO2020243612A1 (en) 2019-05-29 2020-12-03 Rigel Pharmaceuticals, Inc. Method of preventing and treating thrombosis
JP2022543843A (ja) 2019-08-08 2022-10-14 ライジェル ファーマシューティカルズ, インコーポレイテッド サイトカイン放出症候群を治療するための化合物及び方法
CN114286679A (zh) 2019-08-14 2022-04-05 里格尔药品股份有限公司 阻断或改善细胞因子释放综合征的方法
US11911558B2 (en) 2019-09-03 2024-02-27 Trudell Medical International Medical device with energy harvesting system
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
CN118319733A (zh) * 2021-06-01 2024-07-12 高会莉 基于中药雾化的妇科臭氧治疗装置
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
WO2023183377A1 (en) 2022-03-23 2023-09-28 Rigel Pharmaceuticals, Inc. Pyrimid-2-yl-pyrazole compounds as irak inhibitors
CN117258088B (zh) * 2023-11-14 2024-01-16 佛山市南海区第五人民医院(佛山市南海区大沥医院) 一种用于儿科肺炎雾化吸入治疗设备

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898649A (en) 1958-05-06 1962-06-14 Benger Lab Ltd Improvements in and relating to the application of finely divided material
US3187748A (en) * 1963-04-29 1965-06-08 Merck And Company Inc Inhalation-actuated aerosol device
US3456644A (en) * 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
US3456645A (en) * 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
US3456646A (en) * 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
US3565070A (en) * 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
BE758834A (fr) * 1969-11-13 1971-05-12 Riker Laboratoires Inc Distributeur d'aerosol actionne par inhalation
GB1383761A (en) * 1971-02-25 1974-02-12 Woodcraft Dc Inhalation device for use with an aerosol container
US3732864A (en) * 1971-06-07 1973-05-15 Schering Corp Inhalation coordinated aerosol dispensing device
NO134730L (de) * 1971-07-19 1900-01-01
GB1413285A (en) * 1971-11-25 1975-11-12 Bespak Industries Ltd Aerosol devices
US3777742A (en) * 1972-09-18 1973-12-11 Barber Colman Co Tantalum insufflator
GB1479283A (en) 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
US3971377A (en) 1974-06-10 1976-07-27 Alza Corporation Medicament dispensing process for inhalation therapy
US3915165A (en) * 1974-09-13 1975-10-28 Minnesota Mining & Mfg Intratracheal injection system for animals
US3948264A (en) * 1975-05-21 1976-04-06 Mead Johnson & Company Inhalation device
US4109656A (en) * 1977-02-07 1978-08-29 Sybron Corporation Apparatus for use with insufflators
US4147166A (en) 1977-05-02 1979-04-03 American Cyanamid Company Oral inhalator powder dispenser
DE2831553A1 (de) * 1978-07-18 1980-01-31 Siemens Ag Verfahren zur ultraschall-fluessigkeitszerstaeubung
DE2837040C2 (de) * 1978-08-24 1982-10-21 Siemens AG, 1000 Berlin und 8000 München Flüssigkeitstransportsystem für ein Inhalationsgerät
NL8020393A (de) * 1979-10-30 1981-09-01 Riker Laboratories, Inc. Te Loughborough, Groot-Brittannie.
GB2061735B (en) * 1979-10-30 1983-11-30 Riker Laboratories Inc Breath actuated device for administration of powdered medicaments by inhalation
EP0045419B1 (de) * 1980-08-04 1984-10-17 FISONS plc Inhalationsvorrichtung zum Verabreichen von Medikamenten
DE3037917A1 (de) * 1980-10-08 1982-05-13 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Inhaliergeraet
DE3040641A1 (de) * 1980-10-29 1982-05-27 C.H. Boehringer Sohn, 6507 Ingelheim Mundrohr fuer dosieraerosol-geraete
ATE23272T1 (de) * 1981-07-08 1986-11-15 Draco Ab Pulverinhalator.
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
JPS5876038A (ja) * 1981-10-28 1983-05-09 高森 正之 殺虫剤や芳香剤の蒸発装置
FR2516387A1 (fr) * 1981-11-16 1983-05-20 Fabre Sa Pierre Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication
GB2122903B (en) * 1982-06-22 1986-11-05 Masayuki Takamori Vaporizers for vaporisable substances and support media for substances usable therewith
US4576157A (en) * 1983-10-24 1986-03-18 Raghuprasad Puthalath K Oral inhalation apparatus
GB8328808D0 (en) * 1983-10-28 1983-11-30 Riker Laboratories Inc Inhalation responsive dispensers
US4648393A (en) * 1984-11-02 1987-03-10 Ackrad Laboratories, Inc. Breath activated medication spray
US4592348A (en) * 1984-12-17 1986-06-03 Waters Iv William C Aerosol inhaler
US4712460A (en) * 1985-11-18 1987-12-15 Biotrack, Inc. Integrated drug dosage form and metering system
JPS62204756A (ja) * 1986-03-04 1987-09-09 大研医工株式会社 薬剤揮散方法および装置
FR2598918B1 (fr) * 1986-05-23 1988-08-05 Lille Ii Universite Droit Sant Dispositif permettant l'insufflation dans les voies respiratoires d'une poudre radio-opaque a l'etat finement divise
IT1219937B (it) * 1987-05-12 1990-05-24 Glaxo Inc Apparecchio per inalazione
US5031610A (en) * 1987-05-12 1991-07-16 Glaxo Inc. Inhalation device
US5119806A (en) * 1987-05-12 1992-06-09 Glaxo Inc. Inhalation device
DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
ATE224748T1 (de) * 1989-04-28 2002-10-15 Riker Laboratories Inc Inhalationsvorrichtung für trockenpulver
GB8909891D0 (en) * 1989-04-28 1989-06-14 Riker Laboratories Inc Device
GB8919131D0 (en) * 1989-08-23 1989-10-04 Riker Laboratories Inc Inhaler
US5113855A (en) * 1990-02-14 1992-05-19 Newhouse Michael T Powder inhaler
US5060643A (en) * 1990-08-07 1991-10-29 Tenax Corporation Breath-activated inhalation device
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
DE4027390C2 (de) * 1990-08-30 1994-11-03 Boehringer Ingelheim Kg Treibgasfreies Inhalationsgerät
DE4027391A1 (de) * 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5027808A (en) * 1990-10-31 1991-07-02 Tenax Corporation Breath-activated inhalation device
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
FR2700279B1 (fr) * 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
FR2718968B1 (fr) * 1994-04-20 1996-07-26 Valois Sa Insert délimitant une chambre de dosage d'un inhalateur.
FR2738153B1 (fr) * 1995-09-04 1998-01-02 Valois Appareil d'inhalation destine a distribuer des doses precises et reproductibles de produit pulverulent

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AU5539590A (en) 1990-11-29
DE69034007T2 (de) 2003-05-08
US5655523A (en) 1997-08-12
DK0470154T3 (da) 1996-10-21
EP0470154A1 (de) 1992-02-12
AU643435B2 (en) 1993-11-18
DE69027319D1 (de) 1996-07-11
WO1990013327A1 (en) 1990-11-15
CA2058764A1 (en) 1990-10-29
DE69027319T2 (de) 1996-11-21
EP0705614B1 (de) 2002-09-25
US6012454A (en) 2000-01-11
JPH05501505A (ja) 1993-03-25
DE69034007D1 (de) 2002-10-31
EP0705614A1 (de) 1996-04-10
EP0470154B1 (de) 1996-06-05
ES2087911T3 (es) 1996-08-01
ATE138814T1 (de) 1996-06-15

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